Class information for:
Level 1: CREM//CREB//ICER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8733 1223 45.4 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
1709 2             C FOS//EGR 1//IMMEDIATE EARLY GENE 6679
8733 1                   CREM//CREB//ICER 1223

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CREM authKW 790793 5% 57% 56
2 CREB authKW 620871 18% 11% 220
3 ICER authKW 138858 2% 25% 22
4 CRE BINDING PROTEIN authKW 135923 1% 78% 7
5 ATF2 authKW 129498 2% 25% 21
6 CAMP RESPONSE ELEMENT BINDING PROTEIN authKW 113120 3% 13% 34
7 INDUCIBLE CAMP EARLY REPRESSOR authKW 101939 1% 58% 7
8 CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN authKW 88329 2% 19% 19
9 SECT ENDOCRINOL 111H address 79890 0% 80% 4
10 CAMP RESPONSIVE ELEMENT MODULATOR authKW 78015 0% 63% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 3268 27% 0% 335
2 Biochemistry & Molecular Biology 2957 42% 0% 514
3 Neurosciences 1170 20% 0% 243
4 Endocrinology & Metabolism 712 10% 0% 127
5 Oncology 259 10% 0% 117
6 Developmental Biology 188 3% 0% 35
7 Andrology 184 1% 0% 10
8 Genetics & Heredity 168 6% 0% 77
9 Reproductive Biology 120 2% 0% 28
10 Biophysics 91 4% 0% 52

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT ENDOCRINOL 111H 79890 0% 80% 4
2 JONSSON COMPREHENS CANC PEDIAT 49932 0% 100% 2
3 INSERMU18411 RUE HUMANN 33287 0% 67% 2
4 NEURAL CIRCUIT BEHAV 33287 0% 67% 2
5 DIFFERENTIAT TRANSCRIPT 29950 0% 20% 6
6 MOL MECH SYN T PLAST 28083 0% 38% 3
7 PEPTIDE BIOL S 25757 1% 13% 8
8 A1S1 24966 0% 100% 1
9 ABRAHAM RIBICOFF IL PSYCHIAT PHARMA 24966 0% 100% 1
10 ANIM MARINE BIO OURCES SCI REPROD PH 24966 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR ENDOCRINOLOGY 5707 3% 1% 36
2 MOLECULAR AND CELLULAR BIOLOGY 2109 4% 0% 44
3 LEARNING & MEMORY 1883 1% 1% 11
4 JOURNAL OF BIOLOGICAL CHEMISTRY 1686 9% 0% 105
5 ONCOGENE 1040 2% 0% 28
6 NEURON 961 1% 0% 18
7 JOURNAL OF NEUROCHEMISTRY 895 2% 0% 28
8 MOLECULAR BRAIN RESEARCH 776 1% 0% 12
9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 583 4% 0% 50
10 NEUROBIOLOGY OF LEARNING AND MEMORY 554 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CREM 790793 5% 57% 56 Search CREM Search CREM
2 CREB 620871 18% 11% 220 Search CREB Search CREB
3 ICER 138858 2% 25% 22 Search ICER Search ICER
4 CRE BINDING PROTEIN 135923 1% 78% 7 Search CRE+BINDING+PROTEIN Search CRE+BINDING+PROTEIN
5 ATF2 129498 2% 25% 21 Search ATF2 Search ATF2
6 CAMP RESPONSE ELEMENT BINDING PROTEIN 113120 3% 13% 34 Search CAMP+RESPONSE+ELEMENT+BINDING+PROTEIN Search CAMP+RESPONSE+ELEMENT+BINDING+PROTEIN
7 INDUCIBLE CAMP EARLY REPRESSOR 101939 1% 58% 7 Search INDUCIBLE+CAMP+EARLY+REPRESSOR Search INDUCIBLE+CAMP+EARLY+REPRESSOR
8 CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN 88329 2% 19% 19 Search CYCLIC+AMP+RESPONSE+ELEMENT+BINDING+PROTEIN Search CYCLIC+AMP+RESPONSE+ELEMENT+BINDING+PROTEIN
9 CAMP RESPONSIVE ELEMENT MODULATOR 78015 0% 63% 5 Search CAMP+RESPONSIVE+ELEMENT+MODULATOR Search CAMP+RESPONSIVE+ELEMENT+MODULATOR
10 CREM 1 74898 0% 100% 3 Search CREM+1 Search CREM+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MAYR, B , MONTMINY, M , (2001) TRANSCRIPTIONAL REGULATION BY THE PHOSPHORYLATION-DEPENDENT FACTOR CREB.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 2. ISSUE 8. P. 599-609 57 55% 1439
2 SHAYWITZ, AJ , GREENBERG, ME , (1999) CREB: A STIMULUS-INDUCED TRANSCRIPTION FACTOR ACTIVATED BY A DIVERSE ARRAY OF EXTRACELLULAR SIGNALS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 68. ISSUE . P. 821-861 81 40% 1342
3 LONZE, BE , GINTY, DD , (2002) FUNCTION AND REGULATION OF CREB FAMILY TRANSCRIPTION FACTORS IN THE NERVOUS SYSTEM.NEURON. VOL. 35. ISSUE 4. P. 605-623 67 36% 1192
4 BORLIKOVA, G , ENDO, S , (2009) INDUCIBLE CAMP EARLY REPRESSOR (ICER) AND BRAIN FUNCTIONS.MOLECULAR NEUROBIOLOGY. VOL. 40. ISSUE 1. P. 73 -86 61 57% 33
5 BARCO, A , MARIE, H , (2011) GENETIC APPROACHES TO INVESTIGATE THE ROLE OF CREB IN NEURONAL PLASTICITY AND MEMORY.MOLECULAR NEUROBIOLOGY. VOL. 44. ISSUE 3. P. 330 -349 67 42% 43
6 SAKAMOTO, K , KARELINA, K , OBRIETAN, K , (2011) CREB: A MULTIFACETED REGULATOR OF NEURONAL PLASTICITY AND PROTECTION.JOURNAL OF NEUROCHEMISTRY. VOL. 116. ISSUE 1. P. 1 -9 48 42% 126
7 DE CESARE, D , SASSONE-CORSI, P , (2000) TRANSCRIPTIONAL REGULATION BY CYCLIC AMP-RESPONSIVE FACTORS.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 64. VOL. 64. ISSUE . P. 343-369 55 57% 150
8 MONTMINY, M , (1997) TRANSCRIPTIONAL REGULATION BY CYCLIC AMP.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 66. ISSUE . P. 807-822 40 52% 716
9 SASSONECORSI, P , (1995) TRANSCRIPTION FACTORS RESPONSIVE TO CAMP.ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. VOL. 11. ISSUE . P. 355-377 44 65% 274
10 BRIAND, LA , LEE, BG , LELAY, J , KAESTNER, KH , BLENDY, JA , (2015) SERINE 133 PHOSPHORYLATION IS NOT REQUIRED FOR HIPPOCAMPAL CREB-MEDIATED TRANSCRIPTION AND BEHAVIOR.LEARNING & MEMORY. VOL. 22. ISSUE 2. P. 109 -115 33 65% 1

Classes with closest relation at Level 1


Rank Class id link
1 28466 CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1
2 35063 ATF5//ACTIVATING TRANSCRIPTION FACTOR 5//BATF2
3 21300 ATF3//ACTIVATING TRANSCRIPTION FACTOR 3//ACTIVATING TRANSCRIPTION FACTOR 3 ATF3
4 34876 GLIOBLASTOMA CELL STRAIN//UPA PROMOTER//CELL CYCLE PREVALENCE
5 4454 AP 1//FRA 1//JUN
6 27495 UM SYLVESTER BRAMAN FAMILY BREAST CANC//GCN4P//DNA PROMOTER ELEMENTS TRE AND CRE
7 16660 COFFIN LOWRY SYNDROME//RSK2//PHOSPHOHISTONE H3
8 33462 DELTA FOSB//FISHBERG NEUROSCI//FOSB
9 6272 IMMEDIATE EARLY GENE//C FOS//FOS
10 19466 E2A GENE//RAT INSULIN II GENE//UNITE DIABETOL CLIN

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