Class information for:
Level 1: L ASPARAGINASE//ASPARAGINASE//PEG ASPARAGINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8348 1263 32.2 60%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
128 3       BIOTECHNOLOGY & APPLIED MICROBIOLOGY//CELLULASE//XYLANASE 67277
2664 2             L ASPARAGINASE//ASPARAGINASE//SOLID STATE FERMENTATION 3431
8348 1                   L ASPARAGINASE//ASPARAGINASE//PEG ASPARAGINASE 1263

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 L ASPARAGINASE authKW 5103772 23% 71% 296
2 ASPARAGINASE authKW 2646333 13% 64% 170
3 PEG ASPARAGINASE authKW 396688 2% 86% 19
4 ERWINIA ASPARAGINASE authKW 290103 1% 100% 12
5 ACUTE LYMPHOBLASTIC LEUKEMIA authKW 185102 13% 5% 160
6 PEGASPARGASE authKW 175481 1% 52% 14
7 ANTI ASPARAGINASE ANTIBODY authKW 145051 0% 100% 6
8 ASPARAGINE SYNTHETASE authKW 113385 2% 22% 21
9 ASPARAGINASE II authKW 108785 0% 75% 6
10 ASPARAGINASE ACTIVITY authKW 96701 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 9750 27% 0% 342
2 Oncology 2841 26% 0% 325
3 Pediatrics 2520 16% 0% 203
4 Biotechnology & Applied Microbiology 846 12% 0% 154
5 Biochemistry & Molecular Biology 338 18% 0% 223
6 Microbiology 244 7% 0% 91
7 Peripheral Vascular Diseases 68 3% 0% 37
8 Biochemical Research Methods 62 3% 0% 42
9 Pharmacology & Pharmacy 56 7% 0% 84
10 Biophysics 45 3% 0% 42

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALL BFM STUDY 54393 0% 75% 3
2 MICROBIOL SERV DEV PROD 48350 0% 100% 2
3 PEDIAT ONCOL BIOSTAT COMPUTAT BIOL 32232 0% 67% 2
4 AC CIATEJ AC UNIDAD SU TE 24175 0% 100% 1
5 ACT HEMATOL ONCOL 24175 0% 100% 1
6 AL HAWEEJA TECH 24175 0% 100% 1
7 ANDHRA PRADESH IIIT 24175 0% 100% 1
8 AREA SUPPORT MED BATTAL 111THTEXAS ARMY GUA 24175 0% 100% 1
9 BIOL SCI CELLULAR BIOL 24175 0% 100% 1
10 BIOQUIM TECHNOL FARMACEUT 24175 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIATRIC BLOOD & CANCER 11272 4% 1% 46
2 JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY 8125 3% 1% 35
3 KLINISCHE PADIATRIE 3605 2% 1% 20
4 PEDIATRIC HEMATOLOGY AND ONCOLOGY 3022 1% 1% 16
5 AMERICAN JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY 1960 1% 1% 9
6 MEDICAL AND PEDIATRIC ONCOLOGY 1872 1% 1% 14
7 LEUKEMIA & LYMPHOMA 1505 2% 0% 22
8 BRITISH JOURNAL OF HAEMATOLOGY 1464 2% 0% 29
9 CANCER TREATMENT REPORTS 1308 1% 1% 11
10 PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 1053 0% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 L ASPARAGINASE 5103772 23% 71% 296 Search L+ASPARAGINASE Search L+ASPARAGINASE
2 ASPARAGINASE 2646333 13% 64% 170 Search ASPARAGINASE Search ASPARAGINASE
3 PEG ASPARAGINASE 396688 2% 86% 19 Search PEG+ASPARAGINASE Search PEG+ASPARAGINASE
4 ERWINIA ASPARAGINASE 290103 1% 100% 12 Search ERWINIA+ASPARAGINASE Search ERWINIA+ASPARAGINASE
5 ACUTE LYMPHOBLASTIC LEUKEMIA 185102 13% 5% 160 Search ACUTE+LYMPHOBLASTIC+LEUKEMIA Search ACUTE+LYMPHOBLASTIC+LEUKEMIA
6 PEGASPARGASE 175481 1% 52% 14 Search PEGASPARGASE Search PEGASPARGASE
7 ANTI ASPARAGINASE ANTIBODY 145051 0% 100% 6 Search ANTI+ASPARAGINASE+ANTIBODY Search ANTI+ASPARAGINASE+ANTIBODY
8 ASPARAGINE SYNTHETASE 113385 2% 22% 21 Search ASPARAGINE+SYNTHETASE Search ASPARAGINE+SYNTHETASE
9 ASPARAGINASE II 108785 0% 75% 6 Search ASPARAGINASE+II Search ASPARAGINASE+II
10 ASPARAGINASE ACTIVITY 96701 0% 100% 4 Search ASPARAGINASE+ACTIVITY Search ASPARAGINASE+ACTIVITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ALI, U , NAVEED, M , ULLAH, A , ALI, K , SHAH, SA , FAHAD, S , MUMTAZ, AS , (2016) L-ASPARAGINASE AS A CRITICAL COMPONENT TO COMBAT ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A NOVEL APPROACH TO TARGET ALL.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 771. ISSUE . P. 199 -210 77 88% 6
2 BATOOL, T , MAKKY, EA , JALAL, M , YUSOFF, MM , (2016) A COMPREHENSIVE REVIEW ON L-ASPARAGINASE AND ITS APPLICATIONS.APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. VOL. 178. ISSUE 5. P. 900 -923 70 86% 7
3 DE STEFANO, V , ZA, T , CIMINELLO, A , BETTI, S , ROSSI, E , (2015) HAEMOSTATIC ALTERATIONS INDUCED BY TREATMENT WITH ASPARAGINASES AND CLINICAL CONSEQUENCES.THROMBOSIS AND HAEMOSTASIS. VOL. 113. ISSUE 2. P. 247 -261 97 92% 1
4 HIJIYA, N , VAN DER SLUIS, IM , (2016) ASPARAGINASE-ASSOCIATED TOXICITY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA.LEUKEMIA & LYMPHOMA. VOL. 57. ISSUE 4. P. 748 -757 77 80% 3
5 LOPES, AM , DE OLIVEIRA-NASCIMENTO, L , RIBEIRO, A , TAIRUM, CA , BREYER, CA , DE OLIVEIRA, MA , MONTEIRO, G , DE SOUZA-MOTTA, CM , MAGALHAES, PD , AVENDANO, JGF , ET AL (2017) THERAPEUTIC L-ASPARAGINASE: UPSTREAM, DOWNSTREAM AND BEYOND.CRITICAL REVIEWS IN BIOTECHNOLOGY. VOL. 37. ISSUE 1. P. 82 -99 93 75% 0
6 ZUO, SH , ZHANG, T , JIANG, B , MU, WM , (2015) RECENT RESEARCH PROGRESS ON MICROBIAL L-ASPARAGINASES.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 99. ISSUE 3. P. 1069 -1079 62 83% 14
7 SHRIVASTAVA, A , KHAN, AA , KHURSHID, M , KALAM, MA , JAIN, SK , SINGHAL, PK , (2016) RECENT DEVELOPMENTS IN L-ASPARAGINASE DISCOVERY AND ITS POTENTIAL AS ANTICANCER AGENT.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 100. ISSUE . P. 1 -10 55 83% 5
8 VERMA, N , KUMAR, K , KAUR, G , ANAND, S , (2007) L-ASPARAGINASE: A PROMISING CHEMOTHERAPEUTIC AGENT.CRITICAL REVIEWS IN BIOTECHNOLOGY. VOL. 27. ISSUE 1. P. 45 -62 94 65% 67
9 FIGUEIREDO, L , COLE, PD , DRACHTMAN, RA , (2016) ASPARAGINASE ERWINIA CHRYSANTHEMI AS A COMPONENT OF A MULTI-AGENT CHEMOTHERAPEUTIC REGIMEN FOR THE TREATMENT OF PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA WHO HAVE DEVELOPED HYPERSENSITIVITY TO E. COLI-DERIVED ASPARAGINASE.EXPERT REVIEW OF HEMATOLOGY. VOL. 9. ISSUE 3. P. 227 -234 52 83% 3
10 STOCK, W , DOUER, D , DEANGELO, DJ , ARELLANO, M , ADVANI, A , DAMON, L , KOVACSOVICS, T , LITZOW, M , RYTTING, M , BORTHAKUR, G , ET AL (2011) PREVENTION AND MANAGEMENT OF ASPARAGINASE/PEGASPARAGINASE-ASSOCIATED TOXICITIES IN ADULTS AND OLDER ADOLESCENTS: RECOMMENDATIONS OF AN EXPERT PANEL.LEUKEMIA & LYMPHOMA. VOL. 52. ISSUE 12. P. 2237 -2253 67 77% 36

Classes with closest relation at Level 1


Rank Class id link
1 35213 L GLUTAMINASE//MICROCOCCUS LUTEUS K 3//GLUTAMINASE
2 27062 ASPARTYLGLUCOSAMINURIA//GLYCOSYLASPARAGINASE//ASPARTYLGLUCOSAMINIDASE
3 22619 ASPARAGINE SYNTHETASE//ENERGY AND SILAGE MAIZE//ENSILAGED MAIZE
4 6990 ACUTE LYMPHOBLASTIC LEUKEMIA//TESTICULAR RELAPSE//TESTICULAR LEUKEMIA
5 9234 ACUTE LYMPHOBLASTIC LEUKEMIA//PHILADELPHIA CHROMOSOME//ADULT ACUTE LYMPHOBLASTIC LEUKEMIA
6 20765 LEUKOSTASIS//HYPERLEUKOCYTOSIS//LEUCOSTASIS
7 5899 RENAL VEIN THROMBOSIS//NEONATAL THROMBOSIS//DEVELOPMENTAL HAEMOSTASIS
8 7258 PEGYLATION//MONOMETHOXYPOLYETHYLENE GLYCOL//PEGYLATED PROTEINS
9 23814 ARGININE DEIMINASE//ARGININE DEPRIVATION//ARGININOSUCCINATE SYNTHETASE
10 20800 HYPERSENSITIVITY REACTION//HYPERSENSITIVITY//RAPID DESENSITIZATION

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