Class information for:
Level 1: PICHIA PASTORIS//AOX1 PROMOTER//GAP PROMOTER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7325 1381 36.2 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
128 3       BIOTECHNOLOGY & APPLIED MICROBIOLOGY//CELLULASE//XYLANASE 67277
1945 2             PICHIA PASTORIS//TANNASE//YARROWIA LIPOLYTICA 5743
7325 1                   PICHIA PASTORIS//AOX1 PROMOTER//GAP PROMOTER 1381

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PICHIA PASTORIS authKW 3658081 44% 27% 614
2 AOX1 PROMOTER authKW 336204 2% 72% 21
3 GAP PROMOTER authKW 306970 1% 73% 19
4 HANSENULA POLYMORPHA authKW 287246 4% 23% 57
5 METHANOL INDUCTION authKW 276362 1% 83% 15
6 IND BIOTECHNOL METAB ENGN address 215697 1% 51% 19
7 HETEROLOGOUS PROTEIN PRODUCTION authKW 161169 2% 30% 24
8 METHYLOTROPHIC YEAST authKW 159130 3% 20% 36
9 P PASTORIS authKW 117347 1% 28% 19
10 PAOX1 authKW 110547 0% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biotechnology & Applied Microbiology 42383 73% 0% 1008
2 Mycology 3683 7% 0% 93
3 Biochemical Research Methods 1644 12% 0% 169
4 Microbiology 1592 15% 0% 211
5 Biochemistry & Molecular Biology 1360 29% 0% 398
6 Engineering, Chemical 239 7% 0% 95
7 Food Science & Technology 168 5% 0% 71
8 Genetics & Heredity 72 4% 0% 62
9 Biophysics 26 3% 0% 38
10 Agricultural Engineering 15 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IND BIOTECHNOL METAB ENGN 215697 1% 51% 19
2 GLYCOFI 108840 1% 62% 8
3 BIOL PROC DEV IL 92111 1% 42% 10
4 AREA BIOCHEM ENGN 84949 1% 27% 14
5 BIOPROC ENGN ANALYT TECH 66322 0% 50% 6
6 SHANGHAI MUNICIPAL AGRI GENET BREEDING 61411 0% 56% 5
7 BIOL DISCOVERY 59433 1% 24% 11
8 BIOCHEM REACT ENGN 53055 0% 40% 6
9 COLBURN 259 50532 0% 57% 4
10 SEZ UNIT 49745 0% 75% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MICROBIAL CELL FACTORIES 66960 5% 5% 64
2 PROTEIN EXPRESSION AND PURIFICATION 30530 6% 2% 80
3 YEAST 28008 4% 2% 60
4 JOURNAL OF BIOTECHNOLOGY 14967 5% 1% 67
5 FEMS YEAST RESEARCH 12837 2% 2% 30
6 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 10129 6% 1% 80
7 BIOTECHNOLOGY AND BIOENGINEERING 7190 4% 1% 62
8 JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 6527 2% 1% 29
9 BIOTECHNOLOGY PROGRESS 6480 3% 1% 37
10 BIOTECHNOLOGY LETTERS 5618 4% 1% 49

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PICHIA PASTORIS 3658081 44% 27% 614 Search PICHIA+PASTORIS Search PICHIA+PASTORIS
2 AOX1 PROMOTER 336204 2% 72% 21 Search AOX1+PROMOTER Search AOX1+PROMOTER
3 GAP PROMOTER 306970 1% 73% 19 Search GAP+PROMOTER Search GAP+PROMOTER
4 HANSENULA POLYMORPHA 287246 4% 23% 57 Search HANSENULA+POLYMORPHA Search HANSENULA+POLYMORPHA
5 METHANOL INDUCTION 276362 1% 83% 15 Search METHANOL+INDUCTION Search METHANOL+INDUCTION
6 HETEROLOGOUS PROTEIN PRODUCTION 161169 2% 30% 24 Search HETEROLOGOUS+PROTEIN+PRODUCTION Search HETEROLOGOUS+PROTEIN+PRODUCTION
7 METHYLOTROPHIC YEAST 159130 3% 20% 36 Search METHYLOTROPHIC+YEAST Search METHYLOTROPHIC+YEAST
8 P PASTORIS 117347 1% 28% 19 Search P+PASTORIS Search P+PASTORIS
9 PAOX1 110547 0% 100% 5 Search PAOX1 Search PAOX1
10 PORCINE INTERFERON ALPHA 99489 0% 75% 6 Search PORCINE+INTERFERON+ALPHA Search PORCINE+INTERFERON+ALPHA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 POTVIN, G , AHMAD, A , ZHANG, ZS , (2012) BIOPROCESS ENGINEERING ASPECTS OF HETEROLOGOUS PROTEIN PRODUCTION IN PICHIA PASTORIS: A REVIEW.BIOCHEMICAL ENGINEERING JOURNAL. VOL. 64. ISSUE . P. 91 -105 119 73% 63
2 AHMAD, M , HIRZ, M , PICHLER, H , SCHWAB, H , (2014) PROTEIN EXPRESSION IN PICHIA PASTORIS: RECENT ACHIEVEMENTS AND PERSPECTIVES FOR HETEROLOGOUS PROTEIN PRODUCTION.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 98. ISSUE 12. P. 5301 -5317 88 67% 80
3 CALIK, P , ATA, O , GUNES, H , MASSAHI, A , BOY, E , KESKIN, A , OZTURK, S , ZERZE, GH , OZDAMAR, TH , (2015) RECOMBINANT PROTEIN PRODUCTION IN PICHIA PASTORIS UNDER GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE PROMOTER: FROM CARBON SOURCE METABOLISM TO BIOREACTOR OPERATION PARAMETERS.BIOCHEMICAL ENGINEERING JOURNAL. VOL. 95. ISSUE . P. 20 -36 102 73% 10
4 LOOSER, V , BRUHLMANN, B , BUMBAK, F , STENGER, C , COSTA, M , CAMATTARI, A , FOTIADIS, D , KOVAR, K , (2015) CULTIVATION STRATEGIES TO ENHANCE PRODUCTIVITY OF PICHIA PASTORIS: A REVIEW.BIOTECHNOLOGY ADVANCES. VOL. 33. ISSUE 6. P. 1177 -1193 82 75% 10
5 COS, O , RAMON, R , MONTESINOS, JL , VALERO, F , (2006) OPERATIONAL STRATEGIES, MONITORING AND CONTROL OF HETEROLOGOUS PROTEIN PRODUCTION IN THE METHYLOTROPHIC YEAST PICHIA PASTORIS UNDER DIFFERENT PROMOTERS: A REVIEW.MICROBIAL CELL FACTORIES. VOL. 5. ISSUE . P. - 73 85% 110
6 GASSER, B , PRIELHOFER, R , MARX, H , MAURER, M , NOCON, J , STEIGER, M , PUXBAUM, V , SAUER, M , MATTANOVICH, D , (2013) PICHIA PASTORIS: PROTEIN PRODUCTION HOST AND MODEL ORGANISM FOR BIOMEDICAL RESEARCH.FUTURE MICROBIOLOGY. VOL. 8. ISSUE 2. P. 191-208 78 63% 41
7 GAO, MJ , SHI, ZP , (2013) PROCESS CONTROL AND OPTIMIZATION FOR HETEROLOGOUS PROTEIN PRODUCTION BY METHYLOTROPHIC PICHIA PASTORIS.CHINESE JOURNAL OF CHEMICAL ENGINEERING. VOL. 21. ISSUE 2. P. 216-226 64 86% 11
8 KANG, Z , HUANG, H , ZHANG, YF , DU, GC , CHEN, J , (2017) RECENT ADVANCES OF MOLECULAR TOOLBOX CONSTRUCTION EXPAND PICHIA PASTORIS IN SYNTHETIC BIOLOGY APPLICATIONS.WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY. VOL. 33. ISSUE 1. P. - 59 69% 0
9 GONCALVES, AM , PEDRO, AQ , MAIA, C , SOUSA, F , QUEIROZ, JA , PASSARINHA, LA , (2013) PICHIA PASTORIS: A RECOMBINANT MICROFACTORY FOR ANTIBODIES AND HUMAN MEMBRANE PROTEINS.JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 23. ISSUE 5. P. 587-601 55 73% 14
10 PAULOVA, L , HYKA, P , BRANSKA, B , MELZOCH, K , KOVAR, K , (2012) USE OF A MIXTURE OF GLUCOSE AND METHANOL AS SUBSTRATES FOR THE PRODUCTION OF RECOMBINANT TRYPSINOGEN IN CONTINUOUS CULTURES WITH PICHIA PASTORIS MUT(+).JOURNAL OF BIOTECHNOLOGY. VOL. 157. ISSUE 1. P. 180-188 51 82% 12

Classes with closest relation at Level 1


Rank Class id link
1 36009 ARXULA ADENINIVORANS//AUXOTROPHIC SELECTION MARKER//APHO1
2 19532 METHYLOTROPHIC YEAST//ALCOHOL OXIDASE//PICHIA METHANOLICA
3 13617 2 MU M PLASMID//2 MU M CIRCLE//YEP VECTOR
4 19824 NUCLEOTIDE SUGAR TRANSPORTER//UDP GALACTOSE TRANSPORTER//CMP SIALIC ACID TRANSPORTER
5 17898 AMYLOLYTIC YEAST//SCHWANNIOMYCES OCCIDENTALIS//EXTRACELLULAR GLUCOAMYLASE
6 26233 PLECTASIN//JIANGSU SUPERMOL MED MAT PLICAT//FUSION EXPRESSION
7 20614 YARROWIA LIPOLYTICA//GAMMA DECALACTONE//XPR2
8 15795 AMPHIPOLS//UMR 7099//MEMBRANE PROTEIN
9 17023 CELL SURFACE DISPLAY//SURFACE DISPLAY//CELL SURFACE ENGINEERING
10 3838 PLASMID STABILITY//HIGH CELL DENSITY CULTIVATION//RECOMBINANT ESCHERICHIA COLI

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