Class information for:
Level 1: PLASMID STABILITY//HIGH CELL DENSITY CULTIVATION//RECOMBINANT ESCHERICHIA COLI

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3838 1898 30.0 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
18 4 THERMODYNAMICS//ENERGY & FUELS//ENGINEERING, CHEMICAL 531182
283 3       POWDER TECHNOLOGY//ENGINEERING, CHEMICAL//FLUIDIZATION 42723
1005 2             STIRRED TANK//STIRRED VESSEL//MIXING 10375
3838 1                   PLASMID STABILITY//HIGH CELL DENSITY CULTIVATION//RECOMBINANT ESCHERICHIA COLI 1898

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PLASMID STABILITY authKW 291873 3% 28% 66
2 HIGH CELL DENSITY CULTIVATION authKW 233538 2% 44% 33
3 RECOMBINANT ESCHERICHIA COLI authKW 205336 2% 27% 47
4 RECOMBINANT FERMENTATION authKW 151026 1% 72% 13
5 FED BATCH authKW 125032 4% 12% 67
6 BIOTECHNOLOGY AND BIOENGINEERING journal 111085 15% 2% 284
7 ESCHERICHIA COLI authKW 110269 17% 2% 314
8 ACETATE EXCRETION authKW 96519 0% 100% 6
9 SWEDISH BIOPROC TECHNOL address 96519 0% 100% 6
10 SUC2 PROMOTER authKW 93589 0% 73% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biotechnology & Applied Microbiology 68067 79% 0% 1495
2 Engineering, Chemical 2190 15% 0% 289
3 Microbiology 1058 11% 0% 211
4 Food Science & Technology 774 8% 0% 159
5 Biochemical Research Methods 472 6% 0% 117
6 Biochemistry & Molecular Biology 153 12% 0% 231
7 Genetics & Heredity 29 3% 0% 60
8 Engineering, Environmental 13 1% 0% 24
9 Automation & Control Systems 8 1% 0% 16
10 Agricultural Engineering 5 0% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SWEDISH BIOPROC TECHNOL 96519 0% 100% 6
2 AUTOMAT CONTROL TECHNOL 51475 0% 80% 4
3 ESCOLA TECN SUPER ENGN ENGN QUIM 48259 0% 100% 3
4 UNITAT BIOCATALISI LICADA ASSOCIADA IQAC 36193 0% 75% 3
5 SHANDONG BINZHOU ANIM PROPOLIS VACCINE DEV 32173 0% 100% 2
6 SHANDONG BINZHOU DEV PROMOT LIVESTOCK 32173 0% 100% 2
7 BIOCHEM PROC ENGN RU 28953 0% 60% 3
8 BIOPROC SCALE UP IL 28594 0% 44% 4
9 AUTOMAT CONTROL SYST 25929 1% 16% 10
10 SHANDONG BINZHOU ANIM SCI VET MED 24127 0% 50% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTECHNOLOGY AND BIOENGINEERING 111085 15% 2% 284
2 JOURNAL OF BIOTECHNOLOGY 33846 6% 2% 118
3 BIOTECHNOLOGY PROGRESS 30589 5% 2% 94
4 BIOTECHNOLOGY LETTERS 27682 7% 1% 127
5 BIOPROCESS AND BIOSYSTEMS ENGINEERING 16152 2% 2% 43
6 MICROBIAL CELL FACTORIES 13709 2% 3% 34
7 BIOPROCESS ENGINEERING 13653 2% 3% 32
8 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 13428 6% 1% 108
9 BIOTECHNOLOGY TECHNIQUES 11885 2% 2% 33
10 JOURNAL OF FERMENTATION AND BIOENGINEERING 8371 2% 2% 34

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PLASMID STABILITY 291873 3% 28% 66 Search PLASMID+STABILITY Search PLASMID+STABILITY
2 HIGH CELL DENSITY CULTIVATION 233538 2% 44% 33 Search HIGH+CELL+DENSITY+CULTIVATION Search HIGH+CELL+DENSITY+CULTIVATION
3 RECOMBINANT ESCHERICHIA COLI 205336 2% 27% 47 Search RECOMBINANT+ESCHERICHIA+COLI Search RECOMBINANT+ESCHERICHIA+COLI
4 RECOMBINANT FERMENTATION 151026 1% 72% 13 Search RECOMBINANT+FERMENTATION Search RECOMBINANT+FERMENTATION
5 FED BATCH 125032 4% 12% 67 Search FED+BATCH Search FED+BATCH
6 ESCHERICHIA COLI 110269 17% 2% 314 Search ESCHERICHIA+COLI Search ESCHERICHIA+COLI
7 ACETATE EXCRETION 96519 0% 100% 6 Search ACETATE+EXCRETION Search ACETATE+EXCRETION
8 SUC2 PROMOTER 93589 0% 73% 8 Search SUC2+PROMOTER Search SUC2+PROMOTER
9 RECOMBINANT PROTEIN PRODUCTION 86609 2% 14% 38 Search RECOMBINANT+PROTEIN+PRODUCTION Search RECOMBINANT+PROTEIN+PRODUCTION
10 PLASMID INSTABILITY 81090 1% 46% 11 Search PLASMID+INSTABILITY Search PLASMID+INSTABILITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CARNEIRO, S , FERREIRA, EC , ROCHA, I , (2013) METABOLIC RESPONSES TO RECOMBINANT BIOPROCESSES IN ESCHERICHIA COLI.JOURNAL OF BIOTECHNOLOGY. VOL. 164. ISSUE 3. P. 396-408 69 49% 25
2 SHILOACH, J , FASS, R , (2005) GROWING E-COLI TO HIGH CELL DENSITY - A HISTORICAL PERSPECTIVE ON METHOD DEVELOPMENT.BIOTECHNOLOGY ADVANCES. VOL. 23. ISSUE 5. P. 345-357 40 87% 181
3 LEE, SY , (1996) HIGH CELL-DENSITY CULTURE OF ESCHERICHIA COLI.TRENDS IN BIOTECHNOLOGY. VOL. 14. ISSUE 3. P. 98-105 47 75% 446
4 EITEMAN, MA , ALTMAN, E , (2006) OVERCOMING ACETATE IN ESCHERICHIA COLI RECOMBINANT PROTEIN FERMENTATIONS.TRENDS IN BIOTECHNOLOGY. VOL. 24. ISSUE 11. P. 530-536 46 68% 143
5 WAEGEMAN, H , SOETAERT, W , (2011) INCREASING RECOMBINANT PROTEIN PRODUCTION IN ESCHERICHIA COLI THROUGH METABOLIC AND GENETIC ENGINEERING.JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. VOL. 38. ISSUE 12. P. 1891-1910 71 41% 19
6 TRIPATHI, NK , SATHYASEELAN, K , JANA, AM , RAO, PVL , (2009) HIGH YIELD PRODUCTION OF HETEROLOGOUS PROTEINS WITH ESCHERICHIA COLI.DEFENCE SCIENCE JOURNAL. VOL. 59. ISSUE 2. P. 137 -146 39 66% 28
7 DE MEY, M , DE MAESENEIRE, S , SOETAERT, W , VANDAMME, E , (2007) MINIMIZING ACETATE FORMATION IN E-COLI FERMENTATIONS.JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. VOL. 34. ISSUE 11. P. 689 -700 47 52% 47
8 RUIZ, J , GONZALEZ, G , DE MAS, C , LOPEZ-SANTIN, J , (2011) A SEMIEMPIRICAL MODEL TO CONTROL THE PRODUCTION OF A RECOMBINANT ALDOLASE IN HIGH CELL DENSITY CULTURES OF ESCHERICHIA COLI.BIOCHEMICAL ENGINEERING JOURNAL. VOL. 55. ISSUE 2. P. 82 -91 29 83% 1
9 ZHANG, Z , MOOYOUNG, M , CHISTI, Y , (1996) PLASMID STABILITY IN RECOMBINANT SACCHAROMYCES CEREVISIAE.BIOTECHNOLOGY ADVANCES. VOL. 14. ISSUE 4. P. 401-435 49 68% 54
10 FAULKNER, E , BARRETT, M , OKOR, S , KIERAN, P , CASEY, E , PARADISI, F , ENGEL, P , GLENNON, B , (2006) USE OF FED-BATCH CULTIVATION FOR ACHIEVING HIGH CELL DENSITIES FOR THE PILOT-SCALE PRODUCTION OF A RECOMBINANT PROTEIN (PHENYLALANINE DEHYDROGENASE) IN ESCHERICHIA COLI.BIOTECHNOLOGY PROGRESS. VOL. 22. ISSUE 3. P. 889-897 30 86% 8

Classes with closest relation at Level 1


Rank Class id link
1 32857 PENICILLIN PROCESS//FLAVOBACTERIUM DEHYDROGENANS//ABASIDIA COERULEA
2 14520 SCALE DOWN//SHAKE FLASK//AVT BIOCHEM ENGN
3 25773 CYBERNETIC MODEL//SUBSTITUTABLE SUBSTRATES//DYNAMIC METABOLIC MODEL
4 12929 STACKED NEURAL NETWORKS//EXTRACTIVE ALCOHOLIC FERMENTATION//ALCOHOLIC FERMENTATION PROCESS
5 8183 INCLUSION BODIES//PROTEIN REFOLDING//REFOLDING
6 27673 7 AVE COLONEL ROCHE//ALCOHOLIC DRINK PRODUCTION//BIOCHEM CAMPUSVEJ 55
7 10673 BIOPROCESS MONITORING//2D FLUORESCENCE SPECTROSCOPY//SPEKE OPERAT
8 12652 PLASMID PURIFICATION//PLASMID DNA//SUPERCOILED PLASMID DNA
9 8170 PLASMID//REPLICATION CONTROL//PLASMID R6K
10 18228 VTB ENZYMTECHNOL//BACILLUS SUBTILIS//CSSRS

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