Class information for:
Level 1: 4 HYDROXYNONENAL//4 HYDROXY 2 NONENAL//HNE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7185 1395 45.7 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
456 3       VIRGIN OLIVE OIL//OLIVE OIL//HYDROXYTYROSOL 25234
1344 2             4 HYDROXYNONENAL//ACROLEIN//LIPID OXIDATION 8319
7185 1                   4 HYDROXYNONENAL//4 HYDROXY 2 NONENAL//HNE 1395

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 4 HYDROXYNONENAL authKW 2245520 18% 42% 245
2 4 HYDROXY 2 NONENAL authKW 790554 7% 35% 102
3 HNE authKW 302620 3% 37% 37
4 4 HNE authKW 209912 2% 36% 27
5 HYDROXYNONENAL authKW 206707 2% 34% 28
6 4 HYDROXY 2E NONENAL authKW 198975 1% 91% 10
7 4 HYDROXY 2 HEXENAL authKW 165517 1% 69% 11
8 FOOD BIODYNAM address 141442 3% 16% 41
9 LIPID PEROXIDATION authKW 136099 21% 2% 299
10 4 HYDROXYNONENAL HNE authKW 131313 1% 50% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4635 48% 0% 674
2 Toxicology 3096 15% 0% 204
3 Endocrinology & Metabolism 1094 12% 0% 165
4 Chemistry, Medicinal 948 8% 0% 117
5 Biophysics 559 8% 0% 115
6 Biochemical Research Methods 440 7% 0% 95
7 Cell Biology 243 9% 0% 122
8 Pharmacology & Pharmacy 207 10% 0% 135
9 Chemistry, Analytical 186 6% 0% 90
10 Chemistry, Multidisciplinary 96 9% 0% 119

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FOOD BIODYNAM 141442 3% 16% 41
2 SUSTAINABLE ORGAN CHEM 65662 0% 100% 3
3 DIPARTIMENTO MED SPERIMENTALE ONCOL PATOL GEN 43775 0% 100% 2
4 PHARMACEUT SCI HLTH SCI 521 YADA 43775 0% 100% 2
5 ST LUIGI GONZAGA HOSP 43775 0% 100% 2
6 PHYSIOTHER Y GERONTOL 34192 0% 31% 5
7 EXPT MED ONCOL 28220 1% 7% 18
8 DIPARTIMENTO MED ONCOL SPERIMENTALE 25756 1% 8% 15
9 OXIDAT ST S 24629 1% 8% 14
10 ADV FOOD STUDIES BIOCHEM NUTR 21887 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMICAL RESEARCH IN TOXICOLOGY 39566 7% 2% 97
2 FREE RADICAL BIOLOGY AND MEDICINE 37920 9% 1% 122
3 REDOX BIOLOGY 14926 1% 4% 18
4 FREE RADICAL RESEARCH 9502 3% 1% 36
5 CELL BIOCHEMISTRY AND FUNCTION 7639 2% 1% 26
6 REDOX REPORT 3926 1% 1% 13
7 CHEMICO-BIOLOGICAL INTERACTIONS 3440 2% 1% 30
8 BIOFACTORS 2974 1% 1% 14
9 INTERNATIONAL JOURNAL OF TISSUE REACTIONS-EXPERIMENTAL AND CLINICAL ASPECTS 1933 1% 1% 9
10 IRCS MEDICAL SCIENCE-BIOCHEMISTRY 1481 1% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 4 HYDROXYNONENAL 2245520 18% 42% 245 Search 4+HYDROXYNONENAL Search 4+HYDROXYNONENAL
2 4 HYDROXY 2 NONENAL 790554 7% 35% 102 Search 4+HYDROXY+2+NONENAL Search 4+HYDROXY+2+NONENAL
3 HNE 302620 3% 37% 37 Search HNE Search HNE
4 4 HNE 209912 2% 36% 27 Search 4+HNE Search 4+HNE
5 HYDROXYNONENAL 206707 2% 34% 28 Search HYDROXYNONENAL Search HYDROXYNONENAL
6 4 HYDROXY 2E NONENAL 198975 1% 91% 10 Search 4+HYDROXY+2E+NONENAL Search 4+HYDROXY+2E+NONENAL
7 4 HYDROXY 2 HEXENAL 165517 1% 69% 11 Search 4+HYDROXY+2+HEXENAL Search 4+HYDROXY+2+HEXENAL
8 LIPID PEROXIDATION 136099 21% 2% 299 Search LIPID+PEROXIDATION Search LIPID+PEROXIDATION
9 4 HYDROXYNONENAL HNE 131313 1% 50% 12 Search 4+HYDROXYNONENAL+HNE Search 4+HYDROXYNONENAL+HNE
10 4 HYDROXYHEXENAL 128742 1% 59% 10 Search 4+HYDROXYHEXENAL Search 4+HYDROXYHEXENAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 POLI, G , SCHAUR, RJ , SIEMS, WG , LEONARDUZZI, G , (2008) 4-HYDROXYNONENAL: A MEMBRANE LIPID OXIDATION PRODUCT OF MEDICINAL INTEREST.MEDICINAL RESEARCH REVIEWS. VOL. 28. ISSUE 4. P. 569-631 209 54% 192
2 MILKOVIC, L , GASPAROVIC, AC , ZARKOVIC, N , (2015) OVERVIEW ON MAJOR LIPID PEROXIDATION BIOACTIVE FACTOR 4-HYDROXYNONENAL AS PLURIPOTENT GROWTH-REGULATING FACTOR.FREE RADICAL RESEARCH. VOL. 49. ISSUE 7. P. 850 -860 82 79% 7
3 PAROLA, M , BELLOMO, G , ROBINO, G , BARRERA, G , DIANZANI, MU , (1999) 4-HYDROXYNONENAL AS A BIOLOGICAL SIGNAL: MOLECULAR BASIS AND PATHOPHYSIOLOGICAL IMPLICATIONS.ANTIOXIDANTS & REDOX SIGNALING. VOL. 1. ISSUE 3. P. 255 -U21 130 56% 159
4 DALLEAU, S , BARADAT, M , GUERAUD, F , HUC, L , (2013) CELL DEATH AND DISEASES RELATED TO OXIDATIVE STRESS: 4-HYDROXYNONENAL (HNE) IN THE BALANCE.CELL DEATH AND DIFFERENTIATION. VOL. 20. ISSUE 12. P. 1615-1630 79 54% 62
5 SPICKETT, CM , (2013) THE LIPID PEROXIDATION PRODUCT 4-HYDROXY-2-NONENAL: ADVANCES IN CHEMISTRY AND ANALYSIS.REDOX BIOLOGY. VOL. 1. ISSUE 1. P. 145-152 62 76% 40
6 UCHIDA, K , (2003) 4-HYDROXY-2-NONENAL: A PRODUCT AND MEDIATOR OF OXIDATIVE STRESS.PROGRESS IN LIPID RESEARCH. VOL. 42. ISSUE 4. P. 318-343 73 56% 654
7 AYALA, A , MUNOZ, MF , ARGUELLES, S , (2014) LIPID PEROXIDATION: PRODUCTION, METABOLISM, AND SIGNALING MECHANISMS OF MALONDIALDEHYDE AND 4-HYDROXY-2-NONENAL.OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. VOL. . ISSUE . P. - 107 28% 104
8 DUBININA, EE , DADALI, VA , (2010) ROLE OF 4-HYDROXY-TRANS-2-NONENAL IN CELL FUNCTIONS.BIOCHEMISTRY-MOSCOW. VOL. 75. ISSUE 9. P. 1069-1087 82 57% 26
9 GUERAUD, F , ATALAY, M , BRESGEN, N , CIPAK, A , ECKL, PM , HUC, L , JOUANIN, I , SIEMS, W , UCHIDA, K , (2010) CHEMISTRY AND BIOCHEMISTRY OF LIPID PEROXIDATION PRODUCTS.FREE RADICAL RESEARCH. VOL. 44. ISSUE 10. P. 1098-1124 95 36% 155
10 CSALA, M , KARDON, T , LEGEZA, B , LIZAK, B , MANDL, J , MARGITTAI, E , PUSKAS, F , SZARAZ, P , SZELENYI, P , BANHEGYI, G , (2015) ON THE ROLE OF 4-HYDROXYNONENAL IN HEALTH AND DISEASE.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1852. ISSUE 5. P. 826 -838 79 42% 16

Classes with closest relation at Level 1


Rank Class id link
1 18310 ACROLEIN//AMINE PHARMA//PROTEIN CONJUGATED ACROLEIN
2 31206 CARBONYL AMINE REACTIONS//OXIDIZED LIPID PROTEIN REACTIONS//NONENZYMATIC BROWNING
3 12584 ETHENO DNA ADDUCTS//ETHENO ADDUCTS//TOXICOL CANC RISK TORS
4 14853 MALONALDEHYDE//MALONDIALDEHYDE//LIPOFUSCIN LIKE PIGMENTS
5 17028 OXIDIZED PHOSPHOLIPIDS//LEVUGLANDIN//ISOKETALS
6 36572 9 HYDROXYSTEARIC ACID//9 HSA//ENDOGENOUS LIPID PEROXIDATION PRODUCTS
7 9023 PROTEIN OXIDATION//METAL CATALYZED OXIDATION//CLIN PHYS MED
8 22400 OXIDIZED FRYING OIL//OXIDIZED FAT//THERMALLY OXIDIZED OIL
9 11513 ALDEHYDE DEHYDROGENASE//ALDH3A1//MOL TOXICOL ENVIRONM HLTH SCI PROGRAM
10 19665 PLASMALOGEN//ALPHA HYDROXYALDEHYDES//PHOSPHATIDYLETHANOLAMINE PLASMALOGEN

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