Class information for:
Level 1: SOMATIC HYPERMUTATION//ACTIVATION INDUCED CYTIDINE DEAMINASE//CLASS SWITCH RECOMBINATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7148 1400 53.6 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
183 2             IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//SOMATIC HYPERMUTATION 21863
7148 1                   SOMATIC HYPERMUTATION//ACTIVATION INDUCED CYTIDINE DEAMINASE//CLASS SWITCH RECOMBINATION 1400

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOMATIC HYPERMUTATION authKW 1545660 13% 40% 178
2 ACTIVATION INDUCED CYTIDINE DEAMINASE authKW 1196129 6% 63% 87
3 CLASS SWITCH RECOMBINATION authKW 890375 6% 46% 89
4 IMMUNOL GENOM MED address 523614 3% 51% 47
5 ACTIVATION INDUCED DEAMINASE authKW 438407 2% 72% 28
6 AID authKW 359909 6% 19% 86
7 ACTIVATION INDUCED CYTIDINE DEAMINASE AID authKW 253772 1% 73% 16
8 HYPERMUTATION authKW 171205 3% 22% 35
9 DNA EDITING address 167759 1% 77% 10
10 MED CHEM MOL BIOL address 130844 1% 50% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 21106 58% 0% 816
2 Cell Biology 2107 21% 0% 296
3 Biochemistry & Molecular Biology 1753 32% 0% 445
4 Medicine, Research & Experimental 1100 11% 0% 160
5 Genetics & Heredity 497 9% 0% 128
6 Hematology 153 4% 0% 56
7 Oncology 77 6% 0% 85
8 Biology 69 3% 0% 38
9 Toxicology 52 3% 0% 37
10 Allergy 16 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMMUNOL GENOM MED 523614 3% 51% 47
2 DNA EDITING 167759 1% 77% 10
3 MED CHEM MOL BIOL 130844 1% 50% 12
4 SOMAT HYPERMUTAT GRP 87237 0% 100% 4
5 IMMUNE ERS 84111 1% 43% 9
6 DNA HYPERMUTAT CANC GRP 77888 0% 71% 5
7 DNA EDITING IMMUN EPIGENET 68150 0% 63% 5
8 IMMUNOL DISCOVERY GRP 65428 0% 100% 3
9 YOSHIDA SAKYO KU 63079 1% 32% 9
10 LYMPHOCYTE BIOL 52750 1% 17% 14

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF EXPERIMENTAL MEDICINE 23912 8% 1% 116
2 MOLECULAR IMMUNOLOGY 12631 5% 1% 64
3 ADVANCES IN IMMUNOLOGY 9290 1% 3% 16
4 NATURE IMMUNOLOGY 8272 2% 1% 29
5 DNA REPAIR 7775 2% 1% 27
6 JOURNAL OF IMMUNOLOGY 6358 9% 0% 126
7 IMMUNITY 4947 2% 1% 28
8 INTERNATIONAL IMMUNOLOGY 4847 2% 1% 30
9 EUROPEAN JOURNAL OF IMMUNOLOGY 4086 4% 0% 50
10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2509 8% 0% 107

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SOMATIC HYPERMUTATION 1545660 13% 40% 178 Search SOMATIC+HYPERMUTATION Search SOMATIC+HYPERMUTATION
2 ACTIVATION INDUCED CYTIDINE DEAMINASE 1196129 6% 63% 87 Search ACTIVATION+INDUCED+CYTIDINE+DEAMINASE Search ACTIVATION+INDUCED+CYTIDINE+DEAMINASE
3 CLASS SWITCH RECOMBINATION 890375 6% 46% 89 Search CLASS+SWITCH+RECOMBINATION Search CLASS+SWITCH+RECOMBINATION
4 ACTIVATION INDUCED DEAMINASE 438407 2% 72% 28 Search ACTIVATION+INDUCED+DEAMINASE Search ACTIVATION+INDUCED+DEAMINASE
5 AID 359909 6% 19% 86 Search AID Search AID
6 ACTIVATION INDUCED CYTIDINE DEAMINASE AID 253772 1% 73% 16 Search ACTIVATION+INDUCED+CYTIDINE+DEAMINASE+AID Search ACTIVATION+INDUCED+CYTIDINE+DEAMINASE+AID
7 HYPERMUTATION 171205 3% 22% 35 Search HYPERMUTATION Search HYPERMUTATION
8 SOMATIC HYPERMUTATION SHM 118736 1% 78% 7 Search SOMATIC+HYPERMUTATION+SHM Search SOMATIC+HYPERMUTATION+SHM
9 CLASS SWITCH DNA RECOMBINATION CSR 109047 0% 100% 5 Search CLASS+SWITCH+DNA+RECOMBINATION+CSR Search CLASS+SWITCH+DNA+RECOMBINATION+CSR
10 ACTIVATION INDUCED DEAMINASE AID 98139 0% 75% 6 Search ACTIVATION+INDUCED+DEAMINASE+AID Search ACTIVATION+INDUCED+DEAMINASE+AID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MATTHEWS, AJ , ZHENG, SM , DIMENNA, LJ , CHAUDHURI, J , (2014) REGULATION OF IMMUNOGLOBULIN CLASS-SWITCH RECOMBINATION: CHOREOGRAPHY OF NONCODING TRANSCRIPTION, TARGETED DNA DEAMINATION, AND LONG-RANGE DNA REPAIR.ADVANCES IN IMMUNOLOGY, VOL 122. VOL. 122. ISSUE . P. 1 -57 190 68% 14
2 MAUL, RW , GEARHART, PJ , (2010) AID AND SOMATIC HYPERMUTATION.ADVANCES IN IMMUNOLOGY, VOL 105. VOL. 105. ISSUE . P. 159 -191 155 78% 77
3 DI NOLA, JM , NEUBERGER, MS , (2007) MOLECULAR MECHANISMS OF ANTIBODY SOMATIC HYPERMUTATION.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 76. ISSUE . P. 1-22 105 83% 449
4 PELED, JU , KUANG, FL , IGLESIAS-USSEL, MD , ROA, S , KALIS, SL , GOODMAN, ME , SCHARFF, MD , (2008) THE BIOCHEMISTRY OF SOMATIC HYPERMUTATION.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 26. ISSUE . P. 481-511 124 82% 226
5 CASELLAS, R , BASU, U , YEWDELL, WT , CHAUDHURI, J , ROBBIANI, D , DI NOIA, JM , (2016) MUTATIONS, KATAEGIS AND TRANSLOCATIONS IN B CELLS: UNDERSTANDING AID PROMISCUOUS ACTIVITY.NATURE REVIEWS IMMUNOLOGY. VOL. 16. ISSUE 3. P. 164 -176 100 75% 4
6 VUONG, BQ , CHAUDHURI, J , (2012) COMBINATORIAL MECHANISMS REGULATING AID-DEPENDENT DNA DEAMINATION: INTERACTING PROTEINS AND POST-TRANSLATIONAL MODIFICATIONS.SEMINARS IN IMMUNOLOGY. VOL. 24. ISSUE 4. P. 264-272 110 85% 11
7 STORB, U , (2014) WHY DOES SOMATIC HYPERMUTATION BY AID REQUIRE TRANSCRIPTION OF ITS TARGET GENES?.ADVANCES IN IMMUNOLOGY, VOL 122. VOL. 122. ISSUE . P. 253-277 100 83% 14
8 WANG, JH , (2013) THE ROLE OF ACTIVATION-INDUCED DEAMINASE IN ANTIBODY DIVERSIFICATION AND GENOMIC INSTABILITY.IMMUNOLOGIC RESEARCH. VOL. 55. ISSUE 1-3. P. 287-297 117 74% 3
9 ORTHWEIN, A , DI NOIA, JM , (2012) ACTIVATION INDUCED DEAMINASE: HOW MUCH AND WHERE?.SEMINARS IN IMMUNOLOGY. VOL. 24. ISSUE 4. P. 246-254 100 81% 15
10 BARRETO, VM , MAGOR, BG , (2011) ACTIVATION-INDUCED CYTIDINE DEAMINASE STRUCTURE AND FUNCTIONS: A SPECIES COMPARATIVE VIEW.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. VOL. 35. ISSUE 9. P. 991-1007 127 66% 12

Classes with closest relation at Level 1


Rank Class id link
1 8715 ISOTYPE SWITCHING//CLASS SWITCHING//GERMLINE TRANSCRIPTS
2 9090 VIF//APOBEC3G//APOBEC3
3 11197 FOLLICULAR DENDRITIC CELLS//GERMINAL CENTER//CENTROCYTES
4 5392 TRANSLESION SYNTHESIS//TRANSLESION DNA SYNTHESIS//DNA DAMAGE TOLERANCE
5 6004 RIBS//MOLECULAR IMMUNOLOGY//DEXTRAN B512
6 6667 VDJ RECOMBINATION//RAG2//RAG1
7 19522 REPLICATION FORK BARRIER//FORK ARREST//REPLICATION TERMINATOR PROTEIN
8 18474 IMGT//UPR CNRS 1142//REPERTOIRE SEQUENCING
9 26623 PRISTANE//PLASMACYTOMAGENESIS//ABL MYC
10 6059 V H GENE//IMMUNOGLOBULIN GENES//CROSS REACTIVE IDIOTYPE

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