Class information for:
Level 1: AMINOGLYCOSIDES//16S RRNA METHYLASE//AMINOGLYCOSIDE RESISTANCE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7007 1417 41.6 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
233 3       JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLUOROQUINOLONES 48717
2527 2             AMINOGLYCOSIDES//AMINOGLYCOSIDE ANTIBIOTICS//2 DEOXYSTREPTAMINE 3812
7007 1                   AMINOGLYCOSIDES//16S RRNA METHYLASE//AMINOGLYCOSIDE RESISTANCE 1417

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMINOGLYCOSIDES authKW 584618 14% 13% 205
2 16S RRNA METHYLASE authKW 226798 1% 53% 20
3 AMINOGLYCOSIDE RESISTANCE authKW 198016 2% 37% 25
4 RNA RECOGNITION authKW 196191 3% 23% 39
5 AMINOGLYCOSIDE MODIFYING ENZYMES authKW 121187 1% 38% 15
6 AMINOGLYCOSIDE ANTIBIOTICS authKW 114867 2% 17% 32
7 NEAMINE authKW 113348 1% 48% 11
8 RIBOSOMAL A SITE authKW 87980 0% 58% 7
9 16S RRNA METHYLTRANSFERASE authKW 76953 0% 71% 5
10 RMTB authKW 75410 0% 50% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 4459 17% 0% 242
2 Biochemistry & Molecular Biology 3147 41% 0% 574
3 Chemistry, Organic 2721 21% 0% 295
4 Microbiology 2618 19% 0% 268
5 Pharmacology & Pharmacy 808 16% 0% 228
6 Chemistry, Multidisciplinary 374 13% 0% 188
7 Infectious Diseases 280 5% 0% 70
8 Biophysics 218 6% 0% 79
9 Biochemical Research Methods 88 4% 0% 51
10 Biotechnology & Applied Microbiology 81 5% 0% 67

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEM BIOL DOCTORAL PROGRAM 68597 1% 29% 11
2 UMR 5063ICMG FR 2607 57458 0% 67% 4
3 IBIS THER EUT 45896 0% 30% 7
4 CHEM BIOL NAT PROD DESIGNED MOL 41432 0% 38% 5
5 EXCELLENCE STRUCT BIOL 34048 0% 23% 7
6 EDITH JOSEPH FI ER ENZYME INHIBITORS 29826 0% 23% 6
7 CREAT BIOFUNCT MOL 28729 0% 67% 2
8 ROGER ADAMS 361 28729 0% 67% 2
9 PHARMACOCHIM MOLICMG FR 2607 27701 0% 43% 3
10 RNA BIOCHEM 26515 0% 31% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 10142 7% 0% 106
2 CHEMBIOCHEM 7316 3% 1% 39
3 MEDCHEMCOMM 5144 1% 1% 18
4 CHEMISTRY & BIOLOGY 4241 2% 1% 23
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3985 5% 0% 69
6 ACS CHEMICAL BIOLOGY 3587 1% 1% 19
7 BIOCHEMISTRY 3309 6% 0% 92
8 JOURNAL OF ANTIBIOTICS 3065 2% 0% 31
9 BIOORGANIC & MEDICINAL CHEMISTRY 2595 3% 0% 40
10 CARBOHYDRATE RESEARCH 1200 2% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMINOGLYCOSIDES 584618 14% 13% 205 Search AMINOGLYCOSIDES Search AMINOGLYCOSIDES
2 16S RRNA METHYLASE 226798 1% 53% 20 Search 16S+RRNA+METHYLASE Search 16S+RRNA+METHYLASE
3 AMINOGLYCOSIDE RESISTANCE 198016 2% 37% 25 Search AMINOGLYCOSIDE+RESISTANCE Search AMINOGLYCOSIDE+RESISTANCE
4 RNA RECOGNITION 196191 3% 23% 39 Search RNA+RECOGNITION Search RNA+RECOGNITION
5 AMINOGLYCOSIDE MODIFYING ENZYMES 121187 1% 38% 15 Search AMINOGLYCOSIDE+MODIFYING+ENZYMES Search AMINOGLYCOSIDE+MODIFYING+ENZYMES
6 AMINOGLYCOSIDE ANTIBIOTICS 114867 2% 17% 32 Search AMINOGLYCOSIDE+ANTIBIOTICS Search AMINOGLYCOSIDE+ANTIBIOTICS
7 NEAMINE 113348 1% 48% 11 Search NEAMINE Search NEAMINE
8 RIBOSOMAL A SITE 87980 0% 58% 7 Search RIBOSOMAL+A+SITE Search RIBOSOMAL+A+SITE
9 16S RRNA METHYLTRANSFERASE 76953 0% 71% 5 Search 16S+RRNA+METHYLTRANSFERASE Search 16S+RRNA+METHYLTRANSFERASE
10 RMTB 75410 0% 50% 7 Search RMTB Search RMTB

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHANDRIKA, NT , GARNEAU-TSODIKOVA, S , (2016) A REVIEW OF PATENTS (2011-2015) TOWARDS COMBATING RESISTANCE TO AND TOXICITY OF AMINOGLYCOSIDES.MEDCHEMCOMM. VOL. 7. ISSUE 1. P. 50 -68 114 55% 5
2 LABBY, KJ , GARNEAU-TSODIKOVA, S , (2013) STRATEGIES TO OVERCOME THE ACTION OF AMINOGLYCOSIDE-MODIFYING ENZYMES FOR TREATING RESISTANT BACTERIAL INFECTIONS.FUTURE MEDICINAL CHEMISTRY. VOL. 5. ISSUE 11. P. 1285-1309 108 71% 19
3 BERA, S , MONDAL, D , PALIT, S , SCHWEIZER, F , (2016) STRUCTURAL MODIFICATIONS OF THE NEOMYCIN CLASS OF AMINOGLYCOSIDES.MEDCHEMCOMM. VOL. 7. ISSUE 8. P. 1499 -1534 99 74% 0
4 HOUGHTON, JL , GREEN, KD , CHEN, WJ , GARNEAU-TSODIKOVA, S , (2010) THE FUTURE OF AMINOGLYCOSIDES: THE END OR RENAISSANCE?.CHEMBIOCHEM. VOL. 11. ISSUE 7. P. 880 -902 96 64% 64
5 GARNEAU-TSODIKOVA, S , LABBY, KJ , (2016) MECHANISMS OF RESISTANCE TO AMINOGLYCOSIDE ANTIBIOTICS: OVERVIEW AND PERSPECTIVES.MEDCHEMCOMM. VOL. 7. ISSUE 1. P. 11 -27 90 40% 6
6 JIN, Y , WATKINS, D , DEGTYAREVA, NN , GREEN, KD , SPANO, MN , GARNEAU-TSODIKOVA, S , ARYA, DP , (2016) ARGININE-LINKED NEOMYCIN B DIMERS: SYNTHESIS, RRNA BINDING, AND RESISTANCE ENZYME ACTIVITY.MEDCHEMCOMM. VOL. 7. ISSUE 1. P. 164 -169 42 91% 2
7 ROMANOWSKA, J , REUTER, N , TRYLSKA, J , (2013) COMPARING AMINOGLYCOSIDE BINDING SITES IN BACTERIAL RIBOSOMAL RNA AND AMINOGLYCOSIDE MODIFYING ENZYMES.PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. VOL. 81. ISSUE 1. P. 63-80 66 67% 9
8 FOSSO, MY , LI, YJ , GARNEAU-TSODIKOVA, S , (2014) NEW TRENDS IN THE USE OF AMINOGLYCOSIDES.MEDCHEMCOMM. VOL. 5. ISSUE 8. P. 1075 -1091 93 45% 10
9 ZHOU, J , WANG, G , ZHANG, LH , YE, XS , (2007) MODIFICATIONS OF AMINOGOCOSIDE ANTIBIOTICS TARGETING RNA.MEDICINAL RESEARCH REVIEWS. VOL. 27. ISSUE 3. P. 279-316 76 66% 38
10 THOMAS, JR , HERGENROTHER, PJ , (2008) TARGETING RNA WITH SMALL MOLECULES.CHEMICAL REVIEWS. VOL. 108. ISSUE 4. P. 1171 -1224 107 31% 292

Classes with closest relation at Level 1


Rank Class id link
1 30447 5 N N DIMETHYLAMILORIDE//BASELINE MIC CREEP//BENZAMIL HCL
2 19677 ISEPAMICIN//AACC2//DEV OURCES PLANT
3 21261 2 DEOXY SCYLLO INOSOSE SYNTHASE//BUTIROSIN//STREPTOMYCES KANAMYCETICUS
4 12082 RIBOSWITCH//CANC UK NUCLE ACID STRUCT GRP//RNA SWITCH
5 360 RIBOSOME//PEPTIDYL TRANSFERASE//AG RIBOSOMEN
6 22341 AVIBACTAM//CEFTOLOZANE TAZOBACTAM//CEFTAZIDIME AVIBACTAM
7 4242 TAT//TAT PROTEIN//HIV 1 TAT
8 12194 REV//RRE//REV PROTEIN
9 23453 ABASIC SITE//REGULATORY BIOORGAN CHEM//CHIM BIOORGANLEDSS
10 25252 ISOTHERMAL TITRATION CALORIMETRY//ITC//CALORIMETRIC ENTHALPY

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