Class information for:
Level 1: CELL FREE DNA//CIRCULATING DNA//CIRCULATING CELL FREE DNA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6372 1493 37.5 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
563 3       DNA METHYLATION//EPIGENETICS//METHYLATION 17086
382 2             DNA METHYLATION//EPIGENETICS//METHYLATION 17086
6372 1                   CELL FREE DNA//CIRCULATING DNA//CIRCULATING CELL FREE DNA 1493

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL FREE DNA authKW 1733418 11% 51% 167
2 CIRCULATING DNA authKW 1311266 6% 70% 92
3 CIRCULATING CELL FREE DNA authKW 694585 3% 77% 44
4 PLASMA DNA authKW 502660 3% 47% 52
5 CFDNA authKW 393038 2% 62% 31
6 CIRCULATING NUCLEIC ACIDS authKW 347949 2% 52% 33
7 CIRCULATING TUMOR DNA authKW 339391 3% 44% 38
8 LIQUID BIOPSY authKW 218509 3% 25% 43
9 CIRCULATING FREE DNA authKW 174264 1% 61% 14
10 FREE CIRCULATING DNA authKW 157308 1% 77% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medical Laboratory Technology 13928 16% 0% 241
2 Oncology 9547 42% 0% 623
3 Medicine, Research & Experimental 902 10% 0% 152
4 Pathology 413 5% 0% 80
5 Biochemistry & Molecular Biology 217 14% 0% 216
6 Medicine, Legal 139 1% 0% 17
7 Critical Care Medicine 135 2% 0% 33
8 Cell Biology 124 7% 0% 101
9 Multidisciplinary Sciences 85 2% 0% 23
10 Biotechnology & Applied Microbiology 83 5% 0% 70

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIM PHYSIOL VEGETALE 83501 0% 58% 7
2 SYSDIAG UMR3145 54532 0% 67% 4
3 MED KLIN MS ONKOL HAMATOL 42600 0% 42% 5
4 CANC GERIATR 2150B 40901 0% 100% 2
5 CNRS SNC5014 40901 0% 100% 2
6 DM RF 40901 0% 100% 2
7 DURHAM VA MED MED SERV 40901 0% 100% 2
8 ENVIRONM HLTH MOL CARCINOGENESIS 40901 0% 100% 2
9 SERV CHIRURG DIGESTU1071 40901 0% 100% 2
10 SERV VIROL HEPATITE SIDA 40901 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 7063 8% 0% 118
2 CLINICAL CHEMISTRY 4992 4% 0% 54
3 EXPERT REVIEW OF MOLECULAR DIAGNOSTICS 4495 1% 1% 15
4 CLINICAL CANCER RESEARCH 4097 4% 0% 55
5 JOURNAL OF MOLECULAR DIAGNOSTICS 3492 1% 1% 14
6 MOLECULAR ONCOLOGY 3295 1% 1% 11
7 CLINICA CHIMICA ACTA 2220 2% 0% 35
8 EXPERT OPINION ON BIOLOGICAL THERAPY 2175 1% 1% 15
9 INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS 1827 1% 1% 9
10 CLINICAL BIOCHEMISTRY 1563 1% 0% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CELL FREE DNA 1733418 11% 51% 167 Search CELL+FREE+DNA Search CELL+FREE+DNA
2 CIRCULATING DNA 1311266 6% 70% 92 Search CIRCULATING+DNA Search CIRCULATING+DNA
3 CIRCULATING CELL FREE DNA 694585 3% 77% 44 Search CIRCULATING+CELL+FREE+DNA Search CIRCULATING+CELL+FREE+DNA
4 PLASMA DNA 502660 3% 47% 52 Search PLASMA+DNA Search PLASMA+DNA
5 CFDNA 393038 2% 62% 31 Search CFDNA Search CFDNA
6 CIRCULATING NUCLEIC ACIDS 347949 2% 52% 33 Search CIRCULATING+NUCLEIC+ACIDS Search CIRCULATING+NUCLEIC+ACIDS
7 CIRCULATING TUMOR DNA 339391 3% 44% 38 Search CIRCULATING+TUMOR+DNA Search CIRCULATING+TUMOR+DNA
8 LIQUID BIOPSY 218509 3% 25% 43 Search LIQUID+BIOPSY Search LIQUID+BIOPSY
9 CIRCULATING FREE DNA 174264 1% 61% 14 Search CIRCULATING+FREE+DNA Search CIRCULATING+FREE+DNA
10 FREE CIRCULATING DNA 157308 1% 77% 10 Search FREE+CIRCULATING+DNA Search FREE+CIRCULATING+DNA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FLEISCHHACKER, M , SCHMIDT, B , (2007) CIRCULATING NUCLEIC ACIDS (CNAS) AND CANCER - A SURVEY.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1775. ISSUE 1. P. 181 -232 196 53% 314
2 JUNG, K , FLEISCHHACKER, M , RABIEN, A , (2010) CELL-FREE DNA IN THE BLOOD AS A SOLID TUMOR BIOMARKER-A CRITICAL APPRAISAL OF THE LITERATURE.CLINICA CHIMICA ACTA. VOL. 411. ISSUE 21-22. P. 1611-1624 147 71% 113
3 SCHWARZENBACH, H , HOON, DSB , PANTEL, K , (2011) CELL-FREE NUCLEIC ACIDS AS BIOMARKERS IN CANCER PATIENTS.NATURE REVIEWS CANCER. VOL. 11. ISSUE 6. P. 426 -437 81 49% 606
4 ELSHIMALI, YI , KHADDOUR, H , SARKISSYAN, M , WU, YY , VADGAMA, JV , (2013) THE CLINICAL UTILIZATION OF CIRCULATING CELL FREE DNA (CCFDNA) IN BLOOD OF CANCER PATIENTS.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 14. ISSUE 9. P. 18925-18958 113 60% 48
5 GONZALEZ-MASIA, JA , GARCIA-OLMO, D , GARCIA-OLMO, DC , (2013) CIRCULATING NUCLEIC ACIDS IN PLASMA AND SERUM (CNAPS): APPLICATIONS IN ONCOLOGY.ONCOTARGETS AND THERAPY. VOL. 6. ISSUE . P. 819-832 102 64% 27
6 VLASSOV, VV , LAKTIONOV, PP , RYKOVA, EY , (2010) CIRCULATING NUCLEIC ACIDS AS A POTENTIAL SOURCE FOR CANCER BIOMARKERS.CURRENT MOLECULAR MEDICINE. VOL. 10. ISSUE 2. P. 142 -165 120 57% 61
7 MARZESE, DM , HIROSE, H , HOON, DSB , (2013) DIAGNOSTIC AND PROGNOSTIC VALUE OF CIRCULATING TUMOR-RELATED DNA IN CANCER PATIENTS.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 13. ISSUE 8. P. 827 -844 100 58% 24
8 HEITZER, E , ULZ, P , GEIGL, JB , (2015) CIRCULATING TUMOR DNA AS A LIQUID BIOPSY FOR CANCER.CLINICAL CHEMISTRY. VOL. 61. ISSUE 1. P. 112 -123 46 66% 75
9 QIN, Z , LJUBIMOV, VA , ZHOU, CQ , TONG, YG , LIANG, JM , (2016) CELL-FREE CIRCULATING TUMOR DNA IN CANCER.CHINESE JOURNAL OF CANCER. VOL. 35. ISSUE . P. - 69 66% 3
10 ESPOSITO, A , BARDELLI, A , CRISCITIELLO, C , COLOMBO, N , GELAO, L , FUMAGALLI, L , MINCHELLA, I , LOCATELLI, M , GOLDHIRSCH, A , CURIGLIANO, G , (2014) MONITORING TUMOR-DERIVED CELL-FREE DNA IN PATIENTS WITH SOLID TUMORS: CLINICAL PERSPECTIVES AND RESEARCH OPPORTUNITIES.CANCER TREATMENT REVIEWS. VOL. 40. ISSUE 5. P. 648 -655 61 68% 31

Classes with closest relation at Level 1


Rank Class id link
1 21195 STOOL DNA//FECAL RNA//STOOL DNA TESTING
2 14360 GSTP1//UNIDAD DOCENTE BIOQUIM BIOL MOL//DNA METHYLATION
3 4030 CELL FREE FETAL DNA//NON INVASIVE PRENATAL DIAGNOSIS//FETAL DNA
4 27163 MOL DIAGNOST RD//P16INK4A METHYLATION//TRIPLE COMBINATION ARRAY
5 27287 DIGITAL PCR//DROPLET DIGITAL PCR//ACTIVITY BASED BIOMARKERS
6 34402 AFP MRNA//ALPHA FETOPROTEIN MRNA//AFP MESSENGER RNA
7 15761 LUNG CANC PROGRAM//HYPERMETHYLATION//MILTON J DANCE HEAD NECK
8 29102 M65//M30//CYTOKERATIN 18
9 13330 NEUTROPHIL EXTRACELLULAR TRAPS//NETOSIS//NEUTROPHIL EXTRACELLULAR TRAPS NETS
10 624 CIRCULATING TUMOR CELLS//DISSEMINATED TUMOR CELLS//CIRCULATING TUMOUR CELLS

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