Class information for:
Level 1: CANCER ASSOCIATED FIBROBLASTS//JEFFERSON STEM CELL BIOL REGENERAT MED//MANCHESTER BREAST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7275 1387 54.0 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
296 3       BREAST//BREAST CANCER//LYMPHEDEMA 41323
2107 2             LYMPHANGIOGENESIS//VEGF C//PODOPLANIN 5136
7275 1                   CANCER ASSOCIATED FIBROBLASTS//JEFFERSON STEM CELL BIOL REGENERAT MED//MANCHESTER BREAST 1387

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER ASSOCIATED FIBROBLASTS authKW 2470730 15% 52% 214
2 JEFFERSON STEM CELL BIOL REGENERAT MED address 722327 3% 75% 44
3 MANCHESTER BREAST address 478821 3% 51% 43
4 TUMOR STROMA authKW 452357 6% 26% 78
5 CARCINOMA ASSOCIATED FIBROBLASTS authKW 436731 3% 54% 37
6 NEMOSIS authKW 265735 1% 93% 13
7 BREAKTHROUGH BREAST CANC UNIT address 261584 4% 24% 49
8 CAFS authKW 259849 2% 54% 22
9 CANC ENABLING SCI TECHNOLMANCHESTER H address 221970 1% 92% 11
10 STROMA authKW 217734 8% 9% 106

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 18926 60% 0% 830
2 Cell Biology 3837 28% 0% 386
3 Pathology 1173 9% 0% 122
4 Medicine, Research & Experimental 173 5% 0% 74
5 Biochemistry & Molecular Biology 77 11% 0% 153
6 Developmental Biology 62 2% 0% 24
7 Genetics & Heredity 58 4% 0% 58
8 Dentistry, Oral Surgery & Medicine 56 2% 0% 30
9 Cell & Tissue Engineering 51 1% 0% 9
10 Gastroenterology & Hepatology 6 2% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JEFFERSON STEM CELL BIOL REGENERAT MED 722327 3% 75% 44
2 MANCHESTER BREAST 478821 3% 51% 43
3 BREAKTHROUGH BREAST CANC UNIT 261584 4% 24% 49
4 CANC ENABLING SCI TECHNOLMANCHESTER H 221970 1% 92% 11
5 CANC ENABLING SCI TECHNOL 103326 1% 36% 13
6 PATERSON CANC BREAKTHROUGH BREAST CANC R 78618 0% 71% 5
7 PATERSON CANC MANCHESTER BREAST 70442 0% 80% 4
8 REGENERAT MED CANC BIOL 66041 0% 100% 3
9 PATERSON CANC CANC ENABLING SCI TE 58701 0% 67% 4
10 PATERSON CANC MANCHESTER HLTH SCI C 52826 0% 40% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 13446 4% 1% 55
2 BREAST CANCER RESEARCH 5326 2% 1% 23
3 SEMINARS IN CANCER BIOLOGY 5055 1% 1% 16
4 INTERNATIONAL JOURNAL OF CANCER 2996 4% 0% 53
5 MOLECULAR CANCER RESEARCH 2992 1% 1% 16
6 CANCER RESEARCH 2914 5% 0% 73
7 TUMOR BIOLOGY 2570 2% 0% 27
8 CELLULAR ONCOLOGY 2272 1% 1% 7
9 ONCOTARGET 2146 3% 0% 35
10 CANCER CELL 1423 1% 1% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CANCER ASSOCIATED FIBROBLASTS 2470730 15% 52% 214 Search CANCER+ASSOCIATED+FIBROBLASTS Search CANCER+ASSOCIATED+FIBROBLASTS
2 TUMOR STROMA 452357 6% 26% 78 Search TUMOR+STROMA Search TUMOR+STROMA
3 CARCINOMA ASSOCIATED FIBROBLASTS 436731 3% 54% 37 Search CARCINOMA+ASSOCIATED+FIBROBLASTS Search CARCINOMA+ASSOCIATED+FIBROBLASTS
4 NEMOSIS 265735 1% 93% 13 Search NEMOSIS Search NEMOSIS
5 CAFS 259849 2% 54% 22 Search CAFS Search CAFS
6 STROMA 217734 8% 9% 106 Search STROMA Search STROMA
7 TUMOR MICROENVIRONMENT 163801 8% 6% 116 Search TUMOR+MICROENVIRONMENT Search TUMOR+MICROENVIRONMENT
8 MYOFIBROBLAST 123953 8% 5% 107 Search MYOFIBROBLAST Search MYOFIBROBLAST
9 CANCER ASSOCIATED FIBROBLASTS CAFS 117401 1% 67% 8 Search CANCER+ASSOCIATED+FIBROBLASTS+CAFS Search CANCER+ASSOCIATED+FIBROBLASTS+CAFS
10 STROMAL FIBROBLASTS 103326 1% 36% 13 Search STROMAL+FIBROBLASTS Search STROMAL+FIBROBLASTS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GASCARD, P , TLSTY, TD , (2016) CARCINOMA-ASSOCIATED FIBROBLASTS: ORCHESTRATING THE COMPOSITION OF MALIGNANCY.GENES & DEVELOPMENT. VOL. 30. ISSUE 9. P. 1002 -1019 79 61% 11
2 QIAO, AX , GU, F , GUO, XJ , ZHANG, XM , FU, L , (2016) BREAST CANCER-ASSOCIATED FIBROBLASTS: THEIR ROLES IN TUMOR INITIATION, PROGRESSION AND CLINICAL APPLICATIONS.FRONTIERS OF MEDICINE. VOL. 10. ISSUE 1. P. 33 -40 53 58% 7
3 MEZAWA, Y , ORIMO, A , (2016) THE ROLES OF TUMOR- AND METASTASIS-PROMOTING CARCINOMA-ASSOCIATED FIBROBLASTS IN HUMAN CARCINOMAS.CELL AND TISSUE RESEARCH. VOL. 365. ISSUE 3. P. 675 -689 74 50% 3
4 WANG, JY , MIN, AJ , GAO, S , TANG, ZG , (2014) GENETIC REGULATION AND POTENTIALLY THERAPEUTIC APPLICATION OF CANCER-ASSOCIATED FIBROBLASTS IN ORAL CANCER.JOURNAL OF ORAL PATHOLOGY & MEDICINE. VOL. 43. ISSUE 5. P. 323-334 78 58% 2
5 SOTGIA, F , MARTINEZ-OUTSCHOORN, UE , LISANTI, MP , (2013) CANCER METABOLISM: NEW VALIDATED TARGETS FOR DRUG DISCOVERY.ONCOTARGET. VOL. 4. ISSUE 8. P. 1309-1316 46 88% 21
6 LIU, ZM , LIU, MR , LUO, HJ , TU, G , (2015) CANCER-ASSOCIATED FIBROBLASTS: A MULTIFACETED DRIVER OF BREAST CANCER PROGRESSION.CANCER LETTERS. VOL. 361. ISSUE 1. P. 155 -163 63 47% 19
7 MADAR, S , GOLDSTEIN, I , ROTTER, V , (2013) 'CANCER ASSOCIATED FIBROBLASTS' - MORE THAN MEETS THE EYE.TRENDS IN MOLECULAR MEDICINE. VOL. 19. ISSUE 8. P. 447 -453 52 55% 80
8 ROZ, L , CALLARI, M , GANDELLINI, P , ANDRIANI, F , MERLINO, G , D'AIUTO, F , (2015) COMPLEXITY IN THE TUMOUR MICROENVIRONMENT: CANCER ASSOCIATED FIBROBLAST GENE EXPRESSION PATTERNS IDENTIFY BOTH COMMON AND UNIQUE FEATURES OF TUMOUR-STROMA CROSSTALK ACROSS CANCER TYPES.SEMINARS IN CANCER BIOLOGY. VOL. 35. ISSUE . P. 96 -106 61 55% 7
9 LISANTI, MP , MARTINEZ-OUTSCHOORN, UE , SOTGIA, F , (2013) ONCOGENES INDUCE THE CANCER-ASSOCIATED FIBROBLAST PHENOTYPE METABOLIC SYMBIOSIS AND "FIBROBLAST ADDICTION" ARE NEW THERAPEUTIC TARGETS FOR DRUG DISCOVERY.CELL CYCLE. VOL. 12. ISSUE 17. P. 2723-2732 56 61% 25
10 MARTINEZ-OUTSCHOORN, UE , CURRY, JM , KO, YH , LIN, Z , TULUC, M , COGNETTI, D , BIRBE, RC , PRIBITKIN, E , BOMBONATI, A , PESTELL, RG , ET AL (2013) ONCOGENES AND INFLAMMATION REWIRE HOST ENERGY METABOLISM IN THE TUMOR MICROENVIRONMENT RAS AND NF KAPPA B TARGET STROMAL MCT4.CELL CYCLE. VOL. 12. ISSUE 16. P. 2580 -2597 60 57% 18

Classes with closest relation at Level 1


Rank Class id link
1 10122 TUMOR TROPISM//MESENCHYMAL STEM CELLS//VET BIOCHEM IMMUNOL
2 25370 PODOPLANIN//D2 40 ANTIBODY//AGGRUS
3 21633 FIBROCYTES//PROGRAM BIOREGULAT GENET//SERUM AMYLOID P
4 9229 SPHEROID//3D CELL CULTURE//TUMOR SPHEROIDS
5 27092 OCCULT NEOPLASTIC CELLS//FIBROTIC FOCUS//OISO HOSP
6 31678 ENDMT//ENDOTHELIAL MESENCHYMAL TRANSITION//ENDOTHELIAL TO MESENCHYMAL TRANSITION
7 13324 PANCREATIC STELLATE CELLS//PANCREATIC FIBROSIS//PANCREAT GRP
8 30507 MESOTHELIAL CELLS//RAT MAMMARY CARCINOMA//ADHESION POLYPEPTIDES
9 37254 3D SPHEROID ASSAYS//BORTENAT//EARLY EVENTS IN BREAST TUMORIGENESIS
10 5955 TUMOR ASSOCIATED MACROPHAGES//TUMOUR ASSOCIATED MACROPHAGES//MACROPHAGE POLARIZATION

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