Class information for:
Level 1: RETINOIC ACID RECEPTOR//RXR//RETINOYLATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5713 1585 45.9 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
366 3       CROCIN//SAFRANAL//CROCUS SATIVUS L 33995
613 2             VITAMIN A//RETINOIDS//RETINOIC ACID 13982
5713 1                   RETINOIC ACID RECEPTOR//RXR//RETINOYLATION 1585

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RETINOIC ACID RECEPTOR authKW 388419 7% 19% 106
2 RXR authKW 280885 4% 21% 68
3 RETINOYLATION authKW 235974 1% 88% 14
4 RETINOID X RECEPTOR authKW 194700 4% 17% 60
5 RAR authKW 183646 3% 22% 44
6 RETINOIDS authKW 158949 9% 6% 137
7 RETINOBENZOIC ACID authKW 154108 1% 100% 8
8 RXR AGONISTS authKW 154108 1% 100% 8
9 RETINOID RECEPTORS authKW 134351 2% 23% 30
10 9 CIS RETINOIC ACID authKW 133232 2% 22% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4141 43% 0% 689
2 Cell Biology 3214 24% 0% 383
3 Chemistry, Medicinal 2351 12% 0% 190
4 Developmental Biology 1285 6% 0% 96
5 Biophysics 733 9% 0% 139
6 Endocrinology & Metabolism 611 9% 0% 138
7 Chemistry, Organic 167 6% 0% 100
8 Pharmacology & Pharmacy 153 8% 0% 133
9 Dermatology 147 3% 0% 45
10 Oncology 123 7% 0% 107

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RETINOID 83191 1% 24% 18
2 U459 69899 1% 26% 14
3 CELL BIOL SIGNAL TRANSDUCT 51359 1% 33% 8
4 INRA LA 1237 38527 0% 100% 2
5 LES TEMPLIERS 38527 0% 100% 2
6 TSUKUBA BASIC S DRUG DISCOVERY 38527 0% 100% 2
7 BIOCHEMITABASHI KU 36294 0% 27% 7
8 RETINOID PROGRAM 34666 0% 30% 6
9 LIGUE CONTRE CANC 34242 0% 44% 4
10 HUBRECHT UPPSALALAAN 8 25683 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR ENDOCRINOLOGY 5155 2% 1% 39
2 JOURNAL OF MEDICINAL CHEMISTRY 2444 3% 0% 53
3 CELL BIOLOGY REVIEWS 1925 0% 10% 1
4 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1912 3% 0% 51
5 CELL GROWTH & DIFFERENTIATION 1636 1% 1% 11
6 MOLECULAR AND CELLULAR BIOLOGY 1608 3% 0% 44
7 JOURNAL OF BIOLOGICAL CHEMISTRY 1230 7% 0% 104
8 SKIN PHARMACOLOGY 1070 0% 1% 4
9 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 970 4% 0% 61
10 EMBO JOURNAL 899 2% 0% 29

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RETINOIC ACID RECEPTOR 388419 7% 19% 106 Search RETINOIC+ACID+RECEPTOR Search RETINOIC+ACID+RECEPTOR
2 RXR 280885 4% 21% 68 Search RXR Search RXR
3 RETINOYLATION 235974 1% 88% 14 Search RETINOYLATION Search RETINOYLATION
4 RETINOID X RECEPTOR 194700 4% 17% 60 Search RETINOID+X+RECEPTOR Search RETINOID+X+RECEPTOR
5 RAR 183646 3% 22% 44 Search RAR Search RAR
6 RETINOIDS 158949 9% 6% 137 Search RETINOIDS Search RETINOIDS
7 RETINOBENZOIC ACID 154108 1% 100% 8 Search RETINOBENZOIC+ACID Search RETINOBENZOIC+ACID
8 RXR AGONISTS 154108 1% 100% 8 Search RXR+AGONISTS Search RXR+AGONISTS
9 RETINOID RECEPTORS 134351 2% 23% 30 Search RETINOID+RECEPTORS Search RETINOID+RECEPTORS
10 9 CIS RETINOIC ACID 133232 2% 22% 32 Search 9+CIS+RETINOIC+ACID Search 9+CIS+RETINOIC+ACID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LE MAIRE, A , ALVAREZ, S , SHANKARANARAYANAN, P , DE LERA, AR , BOURGUET, W , GRONEMEYER, H , (2012) RETINOID RECEPTORS AND THERAPEUTIC APPLICATIONS OF RAR/RXR MODULATORS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 6. P. 505-527 97 73% 11
2 PEREZ, E , BOURGUET, W , GRONEMEYER, H , DE LERA, AR , (2012) MODULATION OF RXR FUNCTION THROUGH LIGAND DESIGN.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1821. ISSUE 1. P. 57-69 60 58% 54
3 GERMAIN, P , CHAMBON, P , EICHELE, G , EVANS, RM , LAZAR, MA , LEID, M , DE LERA, AR , LOTAN, R , MANGELSDORF, DJ , GRONEMEYER, H , (2006) INTERNATIONAL UNION OF PHARMACOLOGY. LXIII. RETINOID X RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 58. ISSUE 4. P. 760-772 68 48% 244
4 GERMAIN, P , CHAMBON, P , EICHELE, G , EVANS, RM , LAZAR, MA , LEID, M , DE LERA, AR , LOTAN, R , MANGELSDORF, DJ , GRONEMEYER, H , (2006) INTERNATIONAL UNION OF PHARMACOLOGY. LX. RETINOIC ACID RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 58. ISSUE 4. P. 712-725 75 45% 185
5 VAZ, B , DE LERA, AR , (2012) ADVANCES IN DRUG DESIGN WITH RXR MODULATORS.EXPERT OPINION ON DRUG DISCOVERY. VOL. 7. ISSUE 11. P. 1003 -1016 59 63% 6
6 GIGUERE, V , (1994) RETINOIC ACID RECEPTORS AND CELLULAR RETINOID-BINDING PROTEINS - COMPLEX INTERPLAY IN RETINOID SIGNALING.ENDOCRINE REVIEWS. VOL. 15. ISSUE 1. P. 61-79 91 36% 538
7 DAWSON, MI , XIA, ZB , (2012) THE RETINOID X RECEPTORS AND THEIR LIGANDS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1821. ISSUE 1. P. 21 -56 76 32% 72
8 BARNARD, JH , COLLINGS, JC , WHITING, A , PRZYBORSKI, SA , MARDER, TB , (2009) SYNTHETIC RETINOIDS: STRUCTURE-ACTIVITY RELATIONSHIPS.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 15. ISSUE 43. P. 11430-11442 57 56% 17
9 UNDERHILL, TM , KOTCH, LE , LINNEY, E , (1995) RETINOIDS AND MOUSE EMBRYONIC DEVELOPMENT.VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 51. VOL. 51. ISSUE . P. 403-457 105 46% 4
10 AL TANOURY, Z , PISKUNOV, A , ROCHETTE-EGLY, C , (2013) VITAMIN A AND RETINOID SIGNALING: GENOMIC AND NONGENOMIC EFFECTS.JOURNAL OF LIPID RESEARCH. VOL. 54. ISSUE 7. P. 1761-1775 56 36% 59

Classes with closest relation at Level 1


Rank Class id link
1 8638 RETINOIC ACID//CYP26//CYP26A1
2 2704 FENRETINIDE//RETINOIDS//4 HPR
3 13580 CRABP I//CELLULAR RETINOIC ACID BINDING PROTEIN//DIFFERENTIAT CONTROL SECTBLDG 37
4 28495 ACUTE ANTI THY11 GLOMERULONEPHRITIS//ALL TRANS RETINAL RETINAL//ATHEROSCLEROSIS LIPID UNIT
5 2679 THYROID HORMONE RECEPTOR//RESISTANCE TO THYROID HORMONE//V ERBA
6 20282 TR4//GERM CELL NUCLEAR FACTOR//GEORGE WHIPPLE CANC
7 30898 HETEROAROTINOIDS//ANTIHYPERKERATINIZATION//ANTIHYPERPROLIFERATION
8 37228 CLUSTERED HALF SITES//EPIDERMAL KERATIN GENES//LOREAL ADV S
9 2558 ACUTE PROMYELOCYTIC LEUKEMIA//ALL TRANS RETINOIC ACID//APL
10 36710 ANHYDRORETINOL//RETRO RETINOID//14 HYDROXY 4 14 RETRO RETINOL 14HRR

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