Class information for:
Level 1: FENRETINIDE//RETINOIDS//4 HPR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2704 2168 45.6 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
366 3       CROCIN//SAFRANAL//CROCUS SATIVUS L 33995
613 2             VITAMIN A//RETINOIDS//RETINOIC ACID 13982
2704 1                   FENRETINIDE//RETINOIDS//4 HPR 2168

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FENRETINIDE authKW 1121887 5% 69% 115
2 RETINOIDS authKW 674740 15% 15% 330
3 4 HPR authKW 549396 2% 74% 53
4 CD437 authKW 279987 1% 76% 26
5 N 4 HYDROXYPHENYLRETINAMIDE authKW 254192 1% 95% 19
6 TAC 101 authKW 200285 1% 89% 16
7 4HPR authKW 184989 1% 77% 17
8 ATYPICAL RETINOIDS authKW 154911 1% 100% 11
9 ACYCLIC RETINOID authKW 144019 1% 68% 15
10 RETINOID RECEPTORS authKW 141431 2% 28% 36

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 31349 62% 0% 1334
2 Cell Biology 1068 13% 0% 284
3 Biochemistry & Molecular Biology 421 16% 0% 344
4 Pharmacology & Pharmacy 199 8% 0% 179
5 Hematology 109 3% 0% 65
6 Chemistry, Medicinal 59 2% 0% 51
7 Medicine, Research & Experimental 59 3% 0% 69
8 Genetics & Heredity 47 3% 0% 75
9 Dermatology 43 2% 0% 35
10 Nutrition & Dietetics 38 2% 0% 38

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMOPREVENT UNIT 140328 1% 59% 17
2 THORAC HEAD NECK MED ONCOL 129279 5% 9% 103
3 CLIN CANC PREVENT 128955 3% 14% 65
4 RETINOID 60810 1% 24% 18
5 RETINOID PROGRAM 57025 0% 45% 9
6 SECT IMMUNOBIOL DRUG CARRIERS 40958 0% 36% 8
7 CATULLO DANIELA BORGOMAINERIO 32851 0% 33% 7
8 SIGNALING NETWORKS PROGRAM 32001 0% 45% 5
9 CHEBIGEN INC 29333 0% 42% 5
10 UNIT 1360 28742 0% 29% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER RESEARCH 8512 7% 0% 155
2 CLINICAL CANCER RESEARCH 7407 4% 1% 89
3 CANCER LETTERS 5137 3% 1% 67
4 JOURNAL OF THE NATIONAL CANCER INSTITUTE 4776 2% 1% 41
5 INTERNATIONAL JOURNAL OF CANCER 4035 4% 0% 77
6 CANCER PREVENTION RESEARCH 3699 1% 1% 18
7 CARCINOGENESIS 2497 2% 0% 46
8 ANTICANCER RESEARCH 2477 3% 0% 59
9 ONCOGENE 2360 3% 0% 56
10 INTERNATIONAL JOURNAL OF ONCOLOGY 1964 2% 0% 37

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FENRETINIDE 1121887 5% 69% 115 Search FENRETINIDE Search FENRETINIDE
2 RETINOIDS 674740 15% 15% 330 Search RETINOIDS Search RETINOIDS
3 4 HPR 549396 2% 74% 53 Search 4+HPR Search 4+HPR
4 CD437 279987 1% 76% 26 Search CD437 Search CD437
5 N 4 HYDROXYPHENYLRETINAMIDE 254192 1% 95% 19 Search N+4+HYDROXYPHENYLRETINAMIDE Search N+4+HYDROXYPHENYLRETINAMIDE
6 TAC 101 200285 1% 89% 16 Search TAC+101 Search TAC+101
7 4HPR 184989 1% 77% 17 Search 4HPR Search 4HPR
8 ATYPICAL RETINOIDS 154911 1% 100% 11 Search ATYPICAL+RETINOIDS Search ATYPICAL+RETINOIDS
9 ACYCLIC RETINOID 144019 1% 68% 15 Search ACYCLIC+RETINOID Search ACYCLIC+RETINOID
10 RETINOID RECEPTORS 141431 2% 28% 36 Search RETINOID+RECEPTORS Search RETINOID+RECEPTORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DAWSON, MI , FONTANA, JA , (2010) THE PEPTIDOMIMETIC, 1-ADAMANTYL-SUBSTITUTED, AND FLEX-HET CLASSES OF RETINOID-DERIVED MOLECULES: THEIR STRUCTURE-ACTIVITY RELATIONSHIPS AND RETINOID RECEPTOR-INDEPENDENT ANTICANCER ACTIVITIES.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 6. P. 455-491 95 69% 11
2 SIMEONE, AM , TARI, AM , (2004) HOW RETINOIDS REGULATE BREAST CANCER CELL PROLIFERATION AND APOPTOSIS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 61. ISSUE 12. P. 1475-1484 96 69% 75
3 MALONE, W , PERLOFF, M , CROWELL, J , SIGMAN, C , HIGLEY, H , (2003) FENRETINIDE: A PROTOTYPE CANCER PREVENTION DRUG.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 12. ISSUE 11. P. 1829-1842 89 75% 33
4 HAIL, N , KIM, HJ , LOTAN, R , (2006) MECHANISMS OF FENRETINIDE-INDUCED APOPTOSIS.APOPTOSIS. VOL. 11. ISSUE 10. P. 1677-1694 99 49% 106
5 XU, XC , (2007) TUMOR-SUPPRESSIVE ACTIVITY OF RETINOIC ACID RECEPTOR-BETA IN CANCER.CANCER LETTERS. VOL. 253. ISSUE 1. P. 14-24 70 68% 50
6 SOGNO, I , VENE, R , FERRARI, N , DE CENSI, A , IMPERATORI, A , NOONAN, DM , TOSETTI, F , ALBINI, A , (2010) ANGIOPREVENTION WITH FENRETINIDE: TARGETING ANGIOGENESIS IN PREVENTION AND THERAPEUTIC STRATEGIES.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 75. ISSUE 1. P. 2-14 75 61% 16
7 CAZZANIGA, M , VARRICCHIO, C , MONTEFRANCESCO, C , FEROCE, I , GUERRIERI-GONZAGA, A , (2012) FENRETINIDE (4-HPR): A PREVENTIVE CHANCE FOR WOMEN AT GENETIC AND FAMILIAL RISK?.JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY. VOL. . ISSUE . P. - 47 84% 10
8 CHEUNG, E , PINSKI, J , DORFF, T , GROSHEN, S , QUINN, DI , REYNOLDS, CP , MAURER, BJ , LARA, PN , TSAO-WEI, DD , TWARDOWSKI, P , ET AL (2009) ORAL FENRETINIDE IN BIOCHEMICALLY RECURRENT PROSTATE CANCER: A CALIFORNIA CANCER CONSORTIUM PHASE II TRIAL.CLINICAL GENITOURINARY CANCER. VOL. 7. ISSUE 1. P. 43-50 49 84% 8
9 ULUKAYA, E , WOOD, EJ , (1999) FENRETINIDE AND ITS RELATION TO CANCER.CANCER TREATMENT REVIEWS. VOL. 25. ISSUE 4. P. 229-235 57 89% 45
10 BONANNI, B , LAZZERONI, M , VERONESI, U , (2007) SYNTHETIC RETINOID FENRETINIDE IN BREAST CANCER CHEMOPREVENTION.EXPERT REVIEW OF ANTICANCER THERAPY. VOL. 7. ISSUE 4. P. 423-432 59 69% 12

Classes with closest relation at Level 1


Rank Class id link
1 5713 RETINOIC ACID RECEPTOR//RXR//RETINOYLATION
2 13580 CRABP I//CELLULAR RETINOIC ACID BINDING PROTEIN//DIFFERENTIAT CONTROL SECTBLDG 37
3 30898 HETEROAROTINOIDS//ANTIHYPERKERATINIZATION//ANTIHYPERPROLIFERATION
4 36710 ANHYDRORETINOL//RETRO RETINOID//14 HYDROXY 4 14 RETRO RETINOL 14HRR
5 28495 ACUTE ANTI THY11 GLOMERULONEPHRITIS//ALL TRANS RETINAL RETINAL//ATHEROSCLEROSIS LIPID UNIT
6 8638 RETINOIC ACID//CYP26//CYP26A1
7 33037 TIG3//RARRES3//H REV107
8 3733 ISOTRETINOIN//RETINOYL BETA GLUCURONIDE//ACCUTANE
9 17863 UNIV HOSP NA BULOVCE//B TIST ST VINCENTS HLTH SYST//LD CT SCREENING
10 2558 ACUTE PROMYELOCYTIC LEUKEMIA//ALL TRANS RETINOIC ACID//APL

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