Class information for:
Level 1: RETINOIC ACID//CYP26//CYP26A1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8638 1233 53.5 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
366 3       CROCIN//SAFRANAL//CROCUS SATIVUS L 33995
613 2             VITAMIN A//RETINOIDS//RETINOIC ACID 13982
8638 1                   RETINOIC ACID//CYP26//CYP26A1 1233

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RETINOIC ACID authKW 1016550 33% 10% 410
2 CYP26 authKW 804420 4% 69% 47
3 CYP26A1 authKW 785911 4% 72% 44
4 RETINALDEHYDE DEHYDROGENASE authKW 674666 3% 72% 38
5 RALDH2 authKW 484268 3% 53% 37
6 RALDH3 authKW 333650 1% 84% 16
7 LIAROZOLE authKW 297150 1% 67% 18
8 RETINAL DEHYDROGENASE authKW 288148 1% 73% 16
9 RAMBA authKW 261559 1% 81% 13
10 RETINOIDS authKW 238569 12% 7% 148

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Developmental Biology 18349 25% 0% 304
2 Neurosciences 1467 22% 0% 269
3 Anatomy & Morphology 793 4% 0% 45
4 Biochemistry & Molecular Biology 785 24% 0% 299
5 Cell Biology 630 13% 0% 164
6 Pharmacology & Pharmacy 152 9% 0% 112
7 Genetics & Heredity 138 6% 0% 72
8 Nutrition & Dietetics 121 3% 0% 40
9 Toxicology 94 3% 0% 42
10 Dermatology 77 2% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE REGULAT PROGRAM 91418 1% 31% 12
2 NUTR CANC 83681 1% 26% 13
3 E KENNEDY SHRIVER 74290 0% 100% 3
4 ONCODEV BIOL PROGRAM 69155 1% 31% 9
5 EA MENRTUNITE NUTR SIGNALISAT CELLULAIRE 49527 0% 100% 2
6 MHENS NEUROSCI 49527 0% 100% 2
7 UMR 496 49527 0% 100% 2
8 DEV AGING PROGRAM 49214 1% 15% 13
9 MED SCI DERMATOL 36410 0% 29% 5
10 BIOL DIFFERENCIAT EPITHELIALE 33017 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEVELOPMENTAL DYNAMICS 7643 3% 1% 38
2 DEVELOPMENTAL BIOLOGY 6647 5% 0% 61
3 DEVELOPMENT 5024 4% 0% 51
4 MECHANISMS OF DEVELOPMENT 4540 2% 1% 24
5 GENE EXPRESSION PATTERNS 3560 1% 1% 12
6 NEUROTOXICOLOGY AND TERATOLOGY 1446 1% 1% 11
7 JOURNAL OF NEUROBIOLOGY 1174 1% 0% 11
8 INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 1146 1% 0% 11
9 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1016 1% 0% 9
10 BIOCHEMICAL PHARMACOLOGY 556 2% 0% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RETINOIC ACID 1016550 33% 10% 410 Search RETINOIC+ACID Search RETINOIC+ACID
2 CYP26 804420 4% 69% 47 Search CYP26 Search CYP26
3 CYP26A1 785911 4% 72% 44 Search CYP26A1 Search CYP26A1
4 RETINALDEHYDE DEHYDROGENASE 674666 3% 72% 38 Search RETINALDEHYDE+DEHYDROGENASE Search RETINALDEHYDE+DEHYDROGENASE
5 RALDH2 484268 3% 53% 37 Search RALDH2 Search RALDH2
6 RALDH3 333650 1% 84% 16 Search RALDH3 Search RALDH3
7 LIAROZOLE 297150 1% 67% 18 Search LIAROZOLE Search LIAROZOLE
8 RETINAL DEHYDROGENASE 288148 1% 73% 16 Search RETINAL+DEHYDROGENASE Search RETINAL+DEHYDROGENASE
9 RAMBA 261559 1% 81% 13 Search RAMBA Search RAMBA
10 RETINOIDS 238569 12% 7% 148 Search RETINOIDS Search RETINOIDS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RHINN, M , DOLLE, P , (2012) RETINOIC ACID SIGNALLING DURING DEVELOPMENT.DEVELOPMENT. VOL. 139. ISSUE 5. P. 843 -858 86 51% 208
2 NELSON, CH , BUTTRICK, BR , ISOHERRANEN, N , (2013) THERAPEUTIC POTENTIAL OF THE INHIBITION OF THE RETINOIC ACID HYDROXYLASES CYP26A1 AND CYP26B1 BY XENOBIOTICS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 12. P. 1402 -1428 104 59% 5
3 CLAGETT-DAME, M , KNUTSON, D , (2011) VITAMIN A IN REPRODUCTION AND DEVELOPMENT.NUTRIENTS. VOL. 3. ISSUE 4. P. 385 -428 111 44% 83
4 ROSS, AC , ZOLFAGHARI, R , (2011) CYTOCHROME P450S IN THE REGULATION OF CELLULAR RETINOIC ACID METABOLISM.ANNUAL REVIEW OF NUTRITION, VOL 31. VOL. 31. ISSUE . P. 65-87 72 69% 67
5 MADEN, M , (2007) RETINOIC ACID IN THE DEVELOPMENT, REGENERATION AND MAINTENANCE OF THE NERVOUS SYSTEM.NATURE REVIEWS NEUROSCIENCE. VOL. 8. ISSUE 10. P. 755 -765 75 55% 353
6 NIEDERREITHER, K , DOLLE, P , (2008) RETINOIC ACID IN DEVELOPMENT: TOWARDS AN INTEGRATED VIEW.NATURE REVIEWS GENETICS. VOL. 9. ISSUE 7. P. 541 -553 59 48% 287
7 GLOVER, JC , RENAUD, JS , RIJLI, FM , (2006) RETINOIC ACID AND HINDBRAIN PATTERNING.JOURNAL OF NEUROBIOLOGY. VOL. 66. ISSUE 7. P. 705 -725 83 49% 59
8 D'ANIELLO, E , WAXMAN, JS , (2015) INPUT OVERLOAD: CONTRIBUTIONS OF RETINOIC ACID SIGNALING FEEDBACK MECHANISMS TO HEART DEVELOPMENT AND TERATOGENESIS.DEVELOPMENTAL DYNAMICS. VOL. 244. ISSUE 3. P. 513 -523 62 50% 7
9 THATCHER, JE , ISOHERRANEN, N , (2009) THE ROLE OF CYP26 ENZYMES IN RETINOIC ACID CLEARANCE.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 5. ISSUE 8. P. 875-886 58 62% 49
10 MCCAFFERY, P , SIMONS, C , (2007) PROSPECTIVE TERATOLOGY OF RETINOIC ACID METABOLIC BLOCKING AGENTS (RAMBAS) AND LOSS OF CYP26 ACTIVITY.CURRENT PHARMACEUTICAL DESIGN. VOL. 13. ISSUE 29. P. 3020-3037 74 53% 20

Classes with closest relation at Level 1


Rank Class id link
1 5713 RETINOIC ACID RECEPTOR//RXR//RETINOYLATION
2 9208 VISUAL CYCLE//INTERPHOTORECEPTOR RETINOID BINDING PROTEIN//FUNDUS ALBIPUNCTATUS
3 13580 CRABP I//CELLULAR RETINOIC ACID BINDING PROTEIN//DIFFERENTIAT CONTROL SECTBLDG 37
4 28495 ACUTE ANTI THY11 GLOMERULONEPHRITIS//ALL TRANS RETINAL RETINAL//ATHEROSCLEROSIS LIPID UNIT
5 3733 ISOTRETINOIN//RETINOYL BETA GLUCURONIDE//ACCUTANE
6 6298 RHOMBOMERE//HINDBRAIN//PHARYNGEAL ARCH
7 13143 RETINOL BINDING PROTEIN 4//RBP4//RETINOL BINDING PROTEIN
8 21716 ESTUDOS EST SE OXIDAT 32//VITAMIN A TOXICITY//ESTUDOS EST SE OXIDATIVO
9 11513 ALDEHYDE DEHYDROGENASE//ALDH3A1//MOL TOXICOL ENVIRONM HLTH SCI PROGRAM
10 21394 ALVEOLAR REGENERATION//ARONAL R FORTE//VITAMIN A THERAPEUTIC USE

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