Class information for:
Level 1: 7 8 DIHYDROXYFLAVONE//8 DIHYDROXYFLAVONE//TRKB AGONIST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
37080 67 42.4 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
268 3       NEUROTROPHINS//BRAIN DERIVED NEUROTROPHIC FACTOR//BDNF 44049
879 2             NEUROTROPHINS//BRAIN DERIVED NEUROTROPHIC FACTOR//BDNF 11456
37080 1                   7 8 DIHYDROXYFLAVONE//8 DIHYDROXYFLAVONE//TRKB AGONIST 67

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 7 8 DIHYDROXYFLAVONE authKW 6562876 36% 60% 24
2 8 DIHYDROXYFLAVONE authKW 1215348 6% 67% 4
3 TRKB AGONIST authKW 810230 6% 44% 4
4 7 8 DIHYDROXYFLAVONE 7 8 DHF authKW 607674 3% 67% 2
5 7 8 DIHDYROXYFLAVONE authKW 455757 1% 100% 1
6 7 8 DIHYDROXYFIVONE authKW 455757 1% 100% 1
7 7 8 DIHYDROXYFLAVONE HYDRATE authKW 455757 1% 100% 1
8 8 DHF authKW 455757 1% 100% 1
9 DEOXYGEDUNIN authKW 455757 1% 100% 1
10 DEPARMENT MOL NEUROBIOL address 455757 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 761 61% 0% 41
2 Pharmacology & Pharmacy 40 16% 0% 11
3 Behavioral Sciences 22 4% 0% 3
4 Chemistry, Medicinal 21 6% 0% 4
5 Medicine, Research & Experimental 19 7% 0% 5
6 Biochemistry & Molecular Biology 19 18% 0% 12
7 Geriatrics & Gerontology 17 3% 0% 2
8 Psychiatry 12 6% 0% 4
9 Clinical Neurology 7 6% 0% 4
10 Toxicology 4 3% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEPARMENT MOL NEUROBIOL 455757 1% 100% 1
2 MED RETARDAT 364603 3% 40% 2
3 BRAIN COGNIT DYSFUNCT 227877 1% 50% 1
4 OTOLARYNGOL CELL BIOL 227877 1% 50% 1
5 PSYCHIAT EPIGENOM 227877 1% 50% 1
6 SYST IMAGINGWESLEY WOODS HLTH 227877 1% 50% 1
7 BRAIN STIMULAT NEUROPHYSIOL 165726 3% 18% 2
8 CELLMORPHOL MOL NEUROBIOL 113938 1% 25% 1
9 HANYANG AFFILIATED HOSP 113938 1% 25% 1
10 HUBEI FOOD NUTR SAFETY NUTR FOOD 113938 1% 25% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 2061 3% 0% 2
2 ADVANCES IN NEUROLOGY 892 1% 0% 1
3 MOLECULAR NEUROBIOLOGY 823 3% 0% 2
4 HIPPOCAMPUS 767 3% 0% 2
5 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 747 4% 0% 3
6 AMYOTROPHIC LATERAL SCLEROSIS 624 1% 0% 1
7 REJUVENATION RESEARCH 613 1% 0% 1
8 JOURNAL OF MOLECULAR HISTOLOGY 566 1% 0% 1
9 ACS CHEMICAL NEUROSCIENCE 499 1% 0% 1
10 TRANSLATIONAL PSYCHIATRY 486 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 7 8 DIHYDROXYFLAVONE 6562876 36% 60% 24 Search 7+8+DIHYDROXYFLAVONE Search 7+8+DIHYDROXYFLAVONE
2 8 DIHYDROXYFLAVONE 1215348 6% 67% 4 Search 8+DIHYDROXYFLAVONE Search 8+DIHYDROXYFLAVONE
3 TRKB AGONIST 810230 6% 44% 4 Search TRKB+AGONIST Search TRKB+AGONIST
4 7 8 DIHYDROXYFLAVONE 7 8 DHF 607674 3% 67% 2 Search 7+8+DIHYDROXYFLAVONE+7+8+DHF Search 7+8+DIHYDROXYFLAVONE+7+8+DHF
5 7 8 DIHDYROXYFLAVONE 455757 1% 100% 1 Search 7+8+DIHDYROXYFLAVONE Search 7+8+DIHDYROXYFLAVONE
6 7 8 DIHYDROXYFIVONE 455757 1% 100% 1 Search 7+8+DIHYDROXYFIVONE Search 7+8+DIHYDROXYFIVONE
7 7 8 DIHYDROXYFLAVONE HYDRATE 455757 1% 100% 1 Search 7+8+DIHYDROXYFLAVONE+HYDRATE Search 7+8+DIHYDROXYFLAVONE+HYDRATE
8 8 DHF 455757 1% 100% 1 Search 8+DHF Search 8+DHF
9 DEOXYGEDUNIN 455757 1% 100% 1 Search DEOXYGEDUNIN Search DEOXYGEDUNIN
10 PHENOLIC ACID PHENETHYL UREAS 455757 1% 100% 1 Search PHENOLIC+ACID+PHENETHYL+UREAS Search PHENOLIC+ACID+PHENETHYL+UREAS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MA, R , ZHANG, JS , LIU, XY , YUE, SH , ZHAO, Q , XU, Y , (2016) 7,8-DHF TREATMENT INDUCES CYR61 EXPRESSION TO SUPPRESS HYPOXIA INDUCED ER STRESS IN HK-2 CELLS.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 15 34% 0
2 ZHAO, S , GAO, X , DONG, WR , CHEN, JH , (2016) THE ROLE OF 7,8-DIHYDROXYFLAVONE IN PREVENTING DENDRITE DEGENERATION IN CORTEX AFTER MODERATE TRAUMATIC BRAIN INJURY.MOLECULAR NEUROBIOLOGY. VOL. 53. ISSUE 3. P. 1884 -1895 12 27% 3
3 LUO, DD , SHI, Y , WANG, J , LIN, Q , SUN, Y , YE, KQ , YAN, Q , ZHANG, H , (2016) 7,8-DIHYDROXYFLAVONE PROTECTS 6-OHDA AND MPTP INDUCED DOPAMINERGIC NEURONS DEGENERATION THROUGH ACTIVATION OF TRKB IN RODENTS.NEUROSCIENCE LETTERS. VOL. 620. ISSUE . P. 43 -49 9 39% 1
4 LIU, X , OBIANYO, O , CHAN, CB , HUANG, JJ , XUE, SH , YANG, JJ , ZENG, FX , GOODMAN, M , YE, KQ , (2014) BIOCHEMICAL AND BIOPHYSICAL INVESTIGATION OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR MIMETIC 7,8-DIHYDROXYFLAVONE IN THE BINDING AND ACTIVATION OF THE TRKB RECEPTOR.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 289. ISSUE 40. P. 27571 -27584 14 24% 2
5 TAN, Y , NIE, SK , ZHU, WD , LIU, F , GUO, HL , CHU, JW , CAO, XB , JIANG, XJ , ZHANG, YJ , LI, YZ , (2016) 7,8-DIHYDROXYFLAVONE AMELIORATES COGNITIVE IMPAIRMENT BY INHIBITING EXPRESSION OF TAU PATHOLOGY IN APOE-KNOCKOUT MICE.FRONTIERS IN AGING NEUROSCIENCE. VOL. 8. ISSUE . P. - 11 29% 0
6 GAO, L , TIAN, M , ZHAO, HY , XU, QQ , HUANG, YM , SI, QC , TIAN, Q , WU, QM , HU, XM , SUN, LB , ET AL (2016) TRKB ACTIVATION BY 7, 8-DIHYDROXYFLAVONE INCREASES SYNAPSE AMPA SUBUNITS AND AMELIORATES SPATIAL MEMORY DEFICITS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE.JOURNAL OF NEUROCHEMISTRY. VOL. 136. ISSUE 3. P. 620 -636 13 19% 4
7 HE, JJ , XIANG, Z , ZHU, XQ , AI, ZY , SHEN, JS , HUANG, TZ , LIU, LG , JI, WZ , LI, TQ , (2016) NEUROPROTECTIVE EFFECTS OF 7, 8-DIHYDROXYFLAVONE ON MIDBRAIN DOPAMINERGIC NEURONS IN MPP+-TREATED MONKEYS.SCIENTIFIC REPORTS. VOL. 6. ISSUE . P. - 8 36% 0
8 ZHANG, ZT , LIU, X , SCHROEDER, JP , CHAN, CB , SONG, MK , YU, SP , WEINSHENKER, D , YE, KQ , (2014) 7,8-DIHYDROXYFLAVONE PREVENTS SYNAPTIC LOSS AND MEMORY DEFICITS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE.NEUROPSYCHOPHARMACOLOGY. VOL. 39. ISSUE 3. P. 638-650 10 22% 36
9 ZENG, Y , WANG, XN , WANG, Q , LIU, SM , HU, XM , MCCLINTOCK, SM , (2013) SMALL MOLECULES ACTIVATING TRKB RECEPTOR FOR TREATING A VARIETY OF CNS DISORDERS.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 12. ISSUE 7. P. 1066-1077 16 17% 6
10 REN, Q , ZHANG, JC , FUJITA, Y , MA, M , WU, J , HASHIMOTO, K , (2013) EFFECTS OF TRKB AGONIST 7,8-DIHYDROXYFLAVONE ON SENSORY GATING DEFICITS IN MICE AFTER ADMINISTRATION OF METHAMPHETAMINE.PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. VOL. 106. ISSUE . P. 124-127 9 26% 7

Classes with closest relation at Level 1


Rank Class id link
1 8929 P75NTR//P75 NEUROTROPHIN RECEPTOR//PRONGF
2 6148 NEUROTROPHINS//BDNF//TRKB
3 2092 BRAIN DERIVED NEUROTROPHIC FACTOR//BDNF//VAL66MET
4 19066 MOL NUTR GRP//CHEM FOOD PHARM//BLUEBERRY SUPPLEMENTATION
5 35659 EVOLVULUS ALSINOIDES//SHANKHPUSHPI//CONVULVULUS PLURICAULIS
6 33806 MODULAR PHARMACOLOGY//RAS RAF ERK1 2//RAS RAF ERK1 2 SIGNALING PATHWAY
7 12147 SPIRAL GANGLION//SPIRAL GANGLION NEURON//AUDITORY NEURONS
8 18168 TRKA//TRKB//P75NTR
9 36207 KHG21834//2 CYCLOPROPYLIMINO 3 METHYL 1 3 THIAZOLINE HYDROCHLORIDE//CHROMAN 2 CARBOXAMIDE
10 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS

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