Class information for:
Level 1: DIARYLAMIDE//DIARYLUREA//A375P

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
35107 102 26.3 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1452 2             CHRONIC MYELOID LEUKEMIA//IMATINIB//NILOTINIB 7818
35107 1                   DIARYLAMIDE//DIARYLUREA//A375P 102

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIARYLAMIDE authKW 3316084 12% 92% 12
2 DIARYLUREA authKW 2552494 18% 47% 18
3 A375P authKW 1629894 7% 78% 7
4 SORAFENIB ANALOGS authKW 1496844 5% 100% 5
5 1 3 4 TRIARYLPYRAZOLE authKW 1197475 4% 100% 4
6 1H PYRAZOLE 1 CARBOXAMIDE authKW 898107 3% 100% 3
7 3 4 DIARYLPYRAZOLE authKW 898107 3% 100% 3
8 HS 27 authKW 598738 2% 100% 2
9 MULTIPLE KINASE authKW 598738 2% 100% 2
10 RAF 1 KINASE INHIBITORS authKW 598738 2% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 4373 61% 0% 62
2 Chemistry, Organic 304 25% 0% 26
3 Chemistry, Multidisciplinary 150 26% 0% 27
4 Pharmacology & Pharmacy 63 17% 0% 17
5 Crystallography 7 3% 0% 3
6 Biochemistry & Molecular Biology 5 11% 0% 11
7 Oncology 3 5% 0% 5
8 Hematology 1 2% 0% 2
9 Mathematical & Computational Biology 1 1% 0% 1
10 Biochemical Research Methods 1 2% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEM KINOM 346397 9% 13% 9
2 PHARMACOGEN DRUG DEV GRP 342130 4% 29% 4
3 MARINE DRUG RD QMBRI 299369 1% 100% 1
4 MAT 1VIED 299369 1% 100% 1
5 ONCCOL 299369 1% 100% 1
6 QUAL SUPERVISING INSPECTING TESTING ANIM FI 299369 1% 100% 1
7 THOMAS R WATSON MASS SPECT IL 299369 1% 100% 1
8 CHEM KIN 184220 4% 15% 4
9 BIOLSBARRO CANC MOL MED 149683 1% 50% 1
10 ORIGINAL NEW DRUGS DESIGN DISCOVERY 128296 3% 14% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 5440 13% 0% 13
2 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2676 15% 0% 15
3 ARCHIV DER PHARMAZIE 2501 6% 0% 6
4 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 2284 5% 0% 5
5 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 1490 8% 0% 8
6 LETTERS IN DRUG DESIGN & DISCOVERY 886 2% 0% 2
7 MEDICINAL CHEMISTRY RESEARCH 844 3% 0% 3
8 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 613 2% 0% 2
9 MOLECULAR INFORMATICS 608 1% 0% 1
10 BIOORGANIC & MEDICINAL CHEMISTRY 571 5% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DIARYLAMIDE 3316084 12% 92% 12 Search DIARYLAMIDE Search DIARYLAMIDE
2 DIARYLUREA 2552494 18% 47% 18 Search DIARYLUREA Search DIARYLUREA
3 A375P 1629894 7% 78% 7 Search A375P Search A375P
4 SORAFENIB ANALOGS 1496844 5% 100% 5 Search SORAFENIB+ANALOGS Search SORAFENIB+ANALOGS
5 1 3 4 TRIARYLPYRAZOLE 1197475 4% 100% 4 Search 1+3+4+TRIARYLPYRAZOLE Search 1+3+4+TRIARYLPYRAZOLE
6 1H PYRAZOLE 1 CARBOXAMIDE 898107 3% 100% 3 Search 1H+PYRAZOLE+1+CARBOXAMIDE Search 1H+PYRAZOLE+1+CARBOXAMIDE
7 3 4 DIARYLPYRAZOLE 898107 3% 100% 3 Search 3+4+DIARYLPYRAZOLE Search 3+4+DIARYLPYRAZOLE
8 HS 27 598738 2% 100% 2 Search HS+27 Search HS+27
9 MULTIPLE KINASE 598738 2% 100% 2 Search MULTIPLE+KINASE Search MULTIPLE+KINASE
10 RAF 1 KINASE INHIBITORS 598738 2% 100% 2 Search RAF+1+KINASE+INHIBITORS Search RAF+1+KINASE+INHIBITORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 EL-GAMAL, MI , PARK, YS , CHI, DY , YOO, KH , OH, CH , (2013) NEW TRIARYLPYRAZOLES AS BROAD-SPECTRUM ANTICANCER AGENTS: DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 65. ISSUE . P. 315 -322 18 86% 4
2 EL-GAMAL, MI , OH, CH , (2014) DIARYLUREAS AND DIARYLAMIDES WITH PYRROLO[2,3-D]PYRIMIDINE SCAFFOLD AS BROAD-SPECTRUM ANTICANCER AGENTS.CHEMICAL & PHARMACEUTICAL BULLETIN. VOL. 62. ISSUE 1. P. 25 -34 15 79% 1
3 CHOI, WK , EL-GAMAL, MI , CHOI, HS , HONG, JH , BAEK, D , CHOI, K , OH, CH , (2012) DESIGN, SYNTHESIS, AND PRELIMINARY CYTOTOXICITY EVALUATION OF NEW DIARYLUREAS AND DIARYLAMIDES POSSESSING 1,3,4-TRIARYLPYRAZOLE SCAFFOLD.BULLETIN OF THE KOREAN CHEMICAL SOCIETY. VOL. 33. ISSUE 9. P. 2991 -2998 13 81% 3
4 CHO, HJ , EL-GAMAL, MI , OH, CH , LEE, SH , SIM, T , KIM, G , CHOI, HS , CHOI, JH , YOO, KH , (2013) NOVEL QUINOLINYLAMINOISOQUINOLINE BIOISOSTERES OF SORAFENIB AS SELECTIVE RAFI KINASE INHIBITORS: DESIGN, SYNTHESIS, AND ANTIPROLIFERATIVE ACTIVITY AGAINST MELANOMA CELL LINE.CHEMICAL & PHARMACEUTICAL BULLETIN. VOL. 61. ISSUE 7. P. 747 -756 14 67% 0
5 KIM, HJ , EL-GAMAL, MI , LEE, YS , OH, CH , (2013) SYNTHESIS AND PRELIMINARY CYTOTOXICITY EVALUATION OF NEW DIARYLAMIDES AND DIARYLUREAS POSSESSING 2,3-DIHYDROPYRROLO[3,2-B]QUINOLINE SCAFFOLD.BULLETIN OF THE KOREAN CHEMICAL SOCIETY. VOL. 34. ISSUE 8. P. 2480-2486 15 60% 3
6 GARAMVOLGYI, R , DOBOS, J , SIPOS, A , BOROS, S , ILLYES, E , BASKA, F , KEKESI, L , SZABADKAI, I , SZANTAI-KIS, C , KERI, G , ET AL (2016) DESIGN AND SYNTHESIS OF NEW IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO [1,2-A]PYRAZINE DERIVATIVES WITH ANTIPROLIFERATIVE ACTIVITY AGAINST MELANOMA CELLS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 108. ISSUE . P. 623 -643 14 52% 2
7 KOH, EJ , EL-GAMAL, MI , OH, CH , LEE, SH , SIM, T , KIM, G , CHOI, HS , HONG, JH , LEE, S , YOO, KH , (2013) NEW DIARYLAMIDES AND DIARYLUREAS POSSESSING 8-AMINO(ACETAMIDO) QUINOLINE SCAFFOLD: SYNTHESIS, ANTIPROLIFERATIVE ACTIVITIES AGAINST MELANOMA CELL LINES, KINASE INHIBITION, AND IN SILICO STUDIES.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 70. ISSUE . P. 10 -21 14 58% 7
8 EL-GAMAL, MI , KHAN, MA , ABDEL-MAKSOUD, MS , EL-DIN, MMG , OH, CH , (2014) A NEW SERIES OF DIARYLAMIDES POSSESSING QUINOLINE NUCLEUS: SYNTHESIS, IN VITRO ANTICANCER ACTIVITIES, AND KINASE INHIBITORY EFFECT.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 87. ISSUE . P. 484 -492 19 41% 3
9 EL-DIN, MMG , EL-GAMAL, MI , ABDEL-MAKSOUD, MS , YOO, KH , OH, CH , (2015) SYNTHESIS AND BROAD-SPECTRUM ANTIPROLIFERATIVE ACTIVITY OF DIARYLAMIDES AND DIARYLUREAS POSSESSING 1,3,4-OXADIAZOLE DERIVATIVES.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 25. ISSUE 8. P. 1692 -1699 16 44% 3
10 EL-DIN, MMG , EL-GAMAL, MI , ABDEL-MAKSOUD, MS , YOO, KH , OH, CH , (2016) DESIGN, SYNTHESIS, BROAD-SPECTRUM ANTIPROLIFERATIVE ACTIVITY, AND KINASE INHIBITORY EFFECT OF TRIARYLPYRAZOLE DERIVATIVES POSSESSING ARYLAMIDES OR ARYLUREAS MOIETIES.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 119. ISSUE . P. 122 -131 15 48% 0

Classes with closest relation at Level 1


Rank Class id link
1 11421 ANILINOQUINAZOLINE//4 ANILINOQUINAZOLINE//VEGFR 2 INHIBITOR
2 4929 SORAFENIB//HEPATOCELLULAR CARCINOMA//HEPATIC ARTERIAL INFUSION CHEMOTHERAPY
3 1284 VEMURAFENIB//BRAF INHIBITOR//BRAF
4 18265 VANDETANIB//NINTEDANIB//CEDIRANIB
5 11748 RAF//LEO JENKINS CANC//KSR1
6 6326 METASTATIC MELANOMA//BIOCHEMOTHERAPY//DACARBAZINE
7 37680 BRIMONIDINE TARTRATE//4 HYDROXY 5 METHOXYNAPHTHALENE 1 YL ACETATE//ACID BASE DISSOCIATION CONSTANT
8 36270 1 NAPHTHYLAMINES//3 4 BISPHENYLMETHYL 25H FURANONE//3 OXABICYCLO310HEXAN 2 ONE
9 23991 REGORAFENIB//N DESETHYL SUNITINIB//N DESMETHYL IMATINIB
10 35665 TORREYA TAXIFOLIA//2 ETHYLHEXYLPROPANEDIOIC ACID//2 FUNCTIONALIZED ANILINES

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