Class information for:
Level 1: ALPHA BETA ADRENOCEPTOR BLOCKADE//KMUP 1//ACHYRANTHES BIDENTATA POLYPEPTIDES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
32714 135 31.2 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
522 3       MAGNESIUM-BULLETIN//MAGNESIUM RESEARCH//MAGNESIUM 20526
878 2             NEBIVOLOL//CARVEDILOL//BETA BLOCKERS 11463
32714 1                   ALPHA BETA ADRENOCEPTOR BLOCKADE//KMUP 1//ACHYRANTHES BIDENTATA POLYPEPTIDES 135

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALPHA BETA ADRENOCEPTOR BLOCKADE authKW 2261893 7% 100% 10
2 KMUP 1 authKW 2261893 7% 100% 10
3 ACHYRANTHES BIDENTATA POLYPEPTIDES authKW 1130947 4% 100% 5
4 INOTROPIC AND CHRONOTROPIC EFFECTS authKW 678568 2% 100% 3
5 K DR CHANNELS authKW 678568 2% 100% 3
6 PARTIAL BETA2 AGONIST ACTIVITY authKW 678568 2% 100% 3
7 PEDIAT PULMONOL CARDIOL address 626364 4% 46% 6
8 LABEDIPINEDILOL A authKW 508924 2% 75% 3
9 BASILAR ARTERY MYOCYTES authKW 452379 1% 100% 2
10 EUGENOSEDIN A authKW 407138 2% 60% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1864 67% 0% 91
2 Chemistry, Medicinal 195 12% 0% 16
3 Cardiac & Cardiovascular System 75 10% 0% 14
4 Medicine, Research & Experimental 60 9% 0% 12
5 Integrative & Complementary Medicine 16 1% 0% 2
6 Chemistry, Organic 5 4% 0% 6
7 Pathology 4 2% 0% 3
8 Chemistry, Multidisciplinary 4 7% 0% 9
9 Urology & Nephrology 3 2% 0% 3
10 Cell Biology 3 4% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIAT PULMONOL CARDIOL 626364 4% 46% 6
2 COINNOVAT NEUROREGENRAT 226189 1% 100% 1
3 DIPARTIMENTO FARMACOL GEORIO SEGRE 6 226189 1% 100% 1
4 EARTLY CHILDHOOD CARE EDUC 226189 1% 100% 1
5 LIPID SCI AGING MED 226189 1% 100% 1
6 MED PEDIAT PULMONOL CARDIOL 226189 1% 100% 1
7 PEDIAT PULM CARDIOL 226189 1% 100% 1
8 SECT PUL CRIT CARE 226189 1% 100% 1
9 CHILDREN CARE 113094 1% 50% 1
10 ABORAT INNOVAT NEUROREGENERAT 75395 1% 33% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 11296 5% 1% 7
2 DRUG DEVELOPMENT RESEARCH 6216 7% 0% 9
3 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 2958 9% 0% 12
4 JOURNAL OF PHARMACY AND PHARMACOLOGY 2823 7% 0% 10
5 BRITISH JOURNAL OF PHARMACOLOGY 1831 9% 0% 12
6 PHARMACOLOGY 1718 4% 0% 5
7 JOURNAL OF PHARMACOLOGICAL METHODS 1165 1% 0% 2
8 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 897 2% 0% 3
9 PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL 847 2% 0% 3
10 ASIA PACIFIC JOURNAL OF PHARMACOLOGY 797 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALPHA BETA ADRENOCEPTOR BLOCKADE 2261893 7% 100% 10 Search ALPHA+BETA+ADRENOCEPTOR+BLOCKADE Search ALPHA+BETA+ADRENOCEPTOR+BLOCKADE
2 KMUP 1 2261893 7% 100% 10 Search KMUP+1 Search KMUP+1
3 ACHYRANTHES BIDENTATA POLYPEPTIDES 1130947 4% 100% 5 Search ACHYRANTHES+BIDENTATA+POLYPEPTIDES Search ACHYRANTHES+BIDENTATA+POLYPEPTIDES
4 INOTROPIC AND CHRONOTROPIC EFFECTS 678568 2% 100% 3 Search INOTROPIC+AND+CHRONOTROPIC+EFFECTS Search INOTROPIC+AND+CHRONOTROPIC+EFFECTS
5 K DR CHANNELS 678568 2% 100% 3 Search K+DR+CHANNELS Search K+DR+CHANNELS
6 PARTIAL BETA2 AGONIST ACTIVITY 678568 2% 100% 3 Search PARTIAL+BETA2+AGONIST+ACTIVITY Search PARTIAL+BETA2+AGONIST+ACTIVITY
7 LABEDIPINEDILOL A 508924 2% 75% 3 Search LABEDIPINEDILOL+A Search LABEDIPINEDILOL+A
8 BASILAR ARTERY MYOCYTES 452379 1% 100% 2 Search BASILAR+ARTERY+MYOCYTES Search BASILAR+ARTERY+MYOCYTES
9 EUGENOSEDIN A 407138 2% 60% 3 Search EUGENOSEDIN+A Search EUGENOSEDIN+A
10 PHENOXYPROPANOLAMINES 407138 2% 60% 3 Search PHENOXYPROPANOLAMINES Search PHENOXYPROPANOLAMINES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CHIU, CC , WU, JR , LEE, CH , LIOU, SF , DAI, ZK , CHEN, IJ , YEH, JL , (2004) ANTI-HYPERTENSION EFFECT OF VANYLIDILOL: A PHENYLALDEHYDE ALPHA/BETA-ADRENOCEPTOR BLOCKER WITH ENDOTHELIUM-DEPENDENT AND K+ CHANNELS OPENING-ASSOCIATED VASORELAXANT ACTIVITIES.PHARMACOLOGY. VOL. 70. ISSUE 3. P. 140-151 16 53% 4
2 YEH, JL , WU, JR , CHIU, CC , CHEN, YW , LO, YC , LIN, YT , CHENG, CJ , CHEN, IJ , (2002) VANILLYLAMIDE-BASED PROPANOLAMINE DERIVATIVE DISPLAYS ALPHA/BETA-ADRENOCEPTOR BLOCKING AND VASODILATING PROPERTIES.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 39. ISSUE 6. P. 803 -813 12 63% 0
3 CHIU, CC , LIN, YT , TSAI, CH , LIANG, JC , CHIANG, LC , WU, JR , CHEN, IJ , YEH, JL , (2000) PHARMACOLOGICAL EFFECTS OF AN ALDEHYDE TYPE ALPHA/BETA-ADRENOCEPTOR BLOCKING AGENT WITH VASODILATING PROPERTIES.GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM. VOL. 34. ISSUE 6. P. 391-400 14 54% 10
4 YEH, JL , TSAI, CH , LIANG, JC , WU, JR , HUANG, YC , CHEN, IJ , (2001) THIRD-GENERATION DIHYDROPYRIDINE-TYPE CALCIUM CHANNEL BLOCKER LABEDIPINEDILOL-B DISPLAYS ALPHA/BETA-ADRENOCEPTOR BLOCKING ACTIVITIES.DRUG DEVELOPMENT RESEARCH. VOL. 52. ISSUE 3. P. 462 -474 12 55% 0
5 YEH, JL , YANG, TH , LIANG, JC , HUANG, YC , LO, YC , WU, JR , LIN, YT , CHEN, IL , (2000) ISOEUGENODILOL: A VASORELAXANT ALPHA/BETA-ADRENOCEPTOR BLOCKER WITH ANTIOXIDANT ACTIVITY.DRUG DEVELOPMENT RESEARCH. VOL. 51. ISSUE 1. P. 29 -42 14 45% 4
6 YEH, JL , LIOU, SF , LIANG, JC , LEE, CH , CHIU, CC , LIN, YT , CHEN, IJ , (2005) LABEDIPINEDILOL-C: A THIRD-GENERATION DIHYDROPYRIDINE-TYPE CALCIUM CHANNEL ANTAGONIST DISPLAYING K+ CHANNEL OPENING, NO-DEPENDENT AND ADRENERGIC ANTAGONIST ACTIVITIES.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 46. ISSUE 2. P. 130-140 12 41% 3
7 COUMAR, MS , JINDAL, DP , BRUNI, G , MASSARELLI, P , SINGH, R , SHARMA, AK , NANDAKUMAR, K , BODHANKAR, SL , (2008) SYNTHESIS, BETA-ADRENERGIC RECEPTOR BINDING AND ANTIHYPERTENSIVE POTENTIAL OF VANILLIN-DERIVED PHENOXYPROPANOLAMINES.INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY. VOL. 47. ISSUE 6. P. 903 -909 5 83% 0
8 CHIU, CC , CHEN, YW , WU, JR , LIN, YT , CHEN, IJ , YEH, JL , (2002) KMUP 880708: A VANYLLILAMIDE-BASED BETA(1)-ADRENOCEPTOR ANTAGONIST WITH ALPHA-ADRENOCEPTOR BLOCKING AND POTASSIUM CHANNEL OPENING ACTIVITIES.DRUG DEVELOPMENT RESEARCH. VOL. 55. ISSUE 2. P. 104-117 9 53% 1
9 KUO, HF , LAI, YJ , WU, JC , LEE, KT , CHU, CS , CHEN, IJ , WU, JR , WU, BN , (2014) A XANTHINE-DERIVATIVE K+-CHANNEL OPENER PROTECTS AGAINST SEROTONIN-INDUCED CARDIOMYOCYTE HYPERTROPHY VIA THE MODULATION OF PROTEIN KINASES.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. VOL. 10. ISSUE 1. P. 64-72 10 32% 0
10 LIU, CP , YEH, JL , LIOU, SF , WU, BN , CHEN, IJ , (2016) PHOSPHODIESTERASE INHIBITOR KMUP-3 DISPLAYS CARDIOPROTECTION VIA PROTEIN KINASE G AND INCREASES CARDIAC OUTPUT VIA G-PROTEIN-COUPLED RECEPTOR AGONIST ACTIVITY AND CA2+ SENSITIZATION.KAOHSIUNG JOURNAL OF MEDICAL SCIENCES. VOL. 32. ISSUE 2. P. 55 -67 10 30% 0

Classes with closest relation at Level 1


Rank Class id link
1 31463 SHICHIMOTSUKOKATO//AGE DEPENDENT HEMODYNAMIC CHANGE//BENAZEPRIL HYDROCHLORIDE CENTRAL NERVOUS SYSTEM EFFECTS GENERAL PHARMACOLOGY
2 20681 CELIPROLOL//PERINDOPRIL THERAPEUTIC USE//1 BETA ADRENERGIC RECEPTOR
3 18714 EUGENOL//PLATONIN//ASPIRIN EUGENOL ESTER AEE
4 36314 LOCALIZED ADIPOSITY//CARBON DIOXIDE THERAPY//CO2 BATH
5 26532 AGONIST AFFINITY//ANTAGONIST DISSOCIATION CONSTANTS//IRREVERSIBLE RECEPTOR INACTIVATION METHOD
6 15971 CARVEDILOL//TJ0711 HYDROCHLORIDE//CARVEDILOL ENANTIOMERS
7 6581 BETA ADRENOCEPTOR//BETA ADRENERGIC RECEPTOR SUBTYPES//BETA ADRENERGIC RECEPTOR
8 26023 3 4 DIHYDROXY L PHENYL ALANINE//4 HYDROXYNNONENAL//5 HT2B SEROTONIN RECEPTOR AGONIST
9 20336 NEBIVOLOL//NEBIVOLOL HYDROCHLORIDE//THIRD GENERATION BETA BLOCKERS
10 36861 FISIOL CELLUARE//INDENOLOL//K COMPETITION

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