Class information for:
Level 1: CARVEDILOL//TJ0711 HYDROCHLORIDE//CARVEDILOL ENANTIOMERS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15971 680 30.0 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
522 3       MAGNESIUM-BULLETIN//MAGNESIUM RESEARCH//MAGNESIUM 20526
878 2             NEBIVOLOL//CARVEDILOL//BETA BLOCKERS 11463
15971 1                   CARVEDILOL//TJ0711 HYDROCHLORIDE//CARVEDILOL ENANTIOMERS 680

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARVEDILOL authKW 5127929 48% 35% 328
2 TJ0711 HYDROCHLORIDE authKW 179615 1% 100% 4
3 CARVEDILOL ENANTIOMERS authKW 160367 1% 71% 5
4 VASODILATING BETA BLOCKER authKW 143690 1% 80% 4
5 CLIN PHARMACOKINET MODELING SIMULAT address 115460 1% 43% 6
6 CLIN SCI STUDY OPERAT address 102633 1% 57% 4
7 IMPURITY B authKW 101032 0% 75% 3
8 SYMPATHETIC VASCULAR ACTIVITY authKW 101032 0% 75% 3
9 4 HYDROXYPHENYL CARVEDILOL authKW 89807 0% 100% 2
10 AMINOPROPAN 2 OL authKW 89807 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4020 45% 0% 307
2 Cardiac & Cardiovascular System 3020 27% 0% 182
3 Peripheral Vascular Diseases 435 8% 0% 55
4 Chemistry, Analytical 297 10% 0% 70
5 Biochemical Research Methods 142 6% 0% 39
6 Chemistry, Medicinal 112 5% 0% 31
7 Medicine, General & Internal 24 5% 0% 31
8 Endocrinology & Metabolism 12 3% 0% 20
9 Medicine, Research & Experimental 12 3% 0% 19
10 Toxicology 7 2% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN PHARMACOKINET MODELING SIMULAT 115460 1% 43% 6
2 CLIN SCI STUDY OPERAT 102633 1% 57% 4
3 CLIN PHARMACOL STAT PROGRAMMING 86347 1% 38% 5
4 CARDIOVASC METAB STAT PROGRAMMING 59870 0% 67% 2
5 ABT TDCB 44904 0% 100% 1
6 BEL E REP ENTAT OFF 44904 0% 100% 1
7 BIOCHEM PHARMACOGENET 44904 0% 100% 1
8 CARDIAC TRANSPLANT PROGRAM CARDIOL 44904 0% 100% 1
9 DR MANN PHARMA 44904 0% 100% 1
10 HYPERTENS DIS UNIT MED 44904 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 8987 7% 0% 47
2 CLINICAL INVESTIGATOR 6034 1% 1% 9
3 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 4599 4% 0% 27
4 PHARMACOLOGY 2293 2% 0% 13
5 CARDIOVASCULAR DRUGS AND THERAPY 1470 1% 0% 8
6 AMERICAN JOURNAL OF CARDIOLOGY 1105 4% 0% 26
7 ZEITSCHRIFT FUR KARDIOLOGIE 1096 1% 0% 10
8 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 1056 3% 0% 17
9 CARDIOVASCULAR DRUG REVIEWS 956 0% 1% 3
10 AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 954 0% 1% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CARVEDILOL 5127929 48% 35% 328 Search CARVEDILOL Search CARVEDILOL
2 TJ0711 HYDROCHLORIDE 179615 1% 100% 4 Search TJ0711+HYDROCHLORIDE Search TJ0711+HYDROCHLORIDE
3 CARVEDILOL ENANTIOMERS 160367 1% 71% 5 Search CARVEDILOL+ENANTIOMERS Search CARVEDILOL+ENANTIOMERS
4 VASODILATING BETA BLOCKER 143690 1% 80% 4 Search VASODILATING+BETA+BLOCKER Search VASODILATING+BETA+BLOCKER
5 IMPURITY B 101032 0% 75% 3 Search IMPURITY+B Search IMPURITY+B
6 SYMPATHETIC VASCULAR ACTIVITY 101032 0% 75% 3 Search SYMPATHETIC+VASCULAR+ACTIVITY Search SYMPATHETIC+VASCULAR+ACTIVITY
7 4 HYDROXYPHENYL CARVEDILOL 89807 0% 100% 2 Search 4+HYDROXYPHENYL+CARVEDILOL Search 4+HYDROXYPHENYL+CARVEDILOL
8 AMINOPROPAN 2 OL 89807 0% 100% 2 Search AMINOPROPAN+2+OL Search AMINOPROPAN+2+OL
9 KARVILEKS 89807 0% 100% 2 Search KARVILEKS Search KARVILEKS
10 BETA BLOCKERS 74683 11% 2% 73 Search BETA+BLOCKERS Search BETA+BLOCKERS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RABASSEDA, X , (1998) CARVEDILOL: AN EFFECTIVE ANTIHYPERTENSIVE DRUG WITH ANTIISCHEMIC/ANTIOXIDANT CARDIOPROTECTIVE PROPERTIES.DRUGS OF TODAY. VOL. 34. ISSUE 11. P. 905 -926 66 83% 6
2 MCTAVISH, D , CAMPOLIRICHARDS, D , SORKIN, EM , (1993) CARVEDILOL - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC EFFICACY.DRUGS. VOL. 45. ISSUE 2. P. 232-258 64 88% 96
3 DUNN, CJ , LEA, AP , WAGSTAFF, AJ , (1997) CARVEDILOL - A REAPPRAISAL OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN CARDIOVASCULAR DISORDERS.DRUGS. VOL. 54. ISSUE 1. P. 161-185 74 66% 73
4 LI, JW , WANG, L , WANG, SH , CHEN, MC , GU, EM , HU, GX , GE, RS , (2015) SIMULTANEOUS QUANTIFICATION OF CARVEDILOL AND ITS METABOLITES IN RAT PLASMA BY ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY AND PHARMACOKINETIC APPLICATION.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 974. ISSUE . P. 138 -146 31 97% 5
5 PATEL, DP , SHARMA, P , SANYAL, M , SINGHAL, P , SHRIVASTAV, PS , (2013) UPLC-MS/MS ASSAY FOR THE SIMULTANEOUS QUANTIFICATION OF CARVEDILOL AND ITS ACTIVE METABOLITE 4-HYDROXYPHENYL CARVEDILOL IN HUMAN PLASMA TO SUPPORT A BIOEQUIVALENCE STUDY IN HEALTHY VOLUNTEERS.BIOMEDICAL CHROMATOGRAPHY. VOL. 27. ISSUE 8. P. 974-986 29 88% 5
6 CHENG, JH , KAMIYA, K , KODAMA, I , (2001) CARVEDILOL: MOLECULAR AND CELLULAR BASIS FOR ITS MULTIFACETED THERAPEUTIC POTENTIAL.CARDIOVASCULAR DRUG REVIEWS. VOL. 19. ISSUE 2. P. 152 -171 55 52% 59
7 MORGAN, T , (1994) CLINICAL PHARMACOKINETICS AND PHARMACODYNAMICS OF CARVEDILOL.CLINICAL PHARMACOKINETICS. VOL. 26. ISSUE 5. P. 335-346 34 94% 96
8 MEDVEDOVICI, A , ALBU, F , GEORGITA, C , SORA, DI , GALAON, T , UDRESCU, S , DAVID, V , (2007) ACHIRAL-CHIRAL LC/LC-FLD COUPLING FOR DETERMINATION OF CARVEDILOL IN PLASMA SAMPLES FOR BIOEQUIVALENCE PURPOSES.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 850. ISSUE 1-2. P. 327-335 26 87% 16
9 CHEN-SCARABELLI, C , SARAVOLATZ, L , MURAD, Y , SHIEH, WS , QURESHI, W , DI REZZE, J , ABRENCILLO, R , GARDIN, T , GIDWANI, UK , SARAVOLATZ, L , ET AL (2012) A CRITICAL REVIEW OF THE USE OF CARVEDILOL IN ISCHEMIC HEART DISEASE.AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS. VOL. 12. ISSUE 6. P. 391-401 34 55% 14
10 MAGIERA, S , ADOLF, W , BARANOWSKA, I , (2013) SIMULTANEOUS CHIRAL SEPARATION AND DETERMINATION OF CARVEDILOL AND 5'-HYDROXYPHENYL CARVEDILOL ENANTIOMERS FROM HUMAN URINE BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH FLUORESCENT DETECTION.CENTRAL EUROPEAN JOURNAL OF CHEMISTRY. VOL. 11. ISSUE 12. P. 2076-2087 25 76% 2

Classes with closest relation at Level 1


Rank Class id link
1 20336 NEBIVOLOL//NEBIVOLOL HYDROCHLORIDE//THIRD GENERATION BETA BLOCKERS
2 2021 BETA BLOCKERS//HEART FAILURE//CARVEDILOL
3 12676 AMOSULALOL//DILEVALOL//AARHUS CTY HOSP MED 1
4 20681 CELIPROLOL//PERINDOPRIL THERAPEUTIC USE//1 BETA ADRENERGIC RECEPTOR
5 32714 ALPHA BETA ADRENOCEPTOR BLOCKADE//KMUP 1//ACHYRANTHES BIDENTATA POLYPEPTIDES
6 36094 ATHEROGENITY//CAS 57460 41 0//CORDANUM R
7 11131 COLLATERAL CORONARY FLOW//BETA BLOCKERS//METOPROLOL
8 25009 ANTIDIABETIC PHARMACOTHERAPY//A HEFT//ACORN CSD
9 26023 3 4 DIHYDROXY L PHENYL ALANINE//4 HYDROXYNNONENAL//5 HT2B SEROTONIN RECEPTOR AGONIST
10 7286 ATENOLOL//4 HYDROXYPROPRANOLOL//METOPROLOL

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