Class information for:
Level 1: PENETRATION ENHANCER//PERCUTANEOUS ABSORPTION//TRANSDERMAL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
320 3655 28.6 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
12 4 POLYMER SCIENCE//MATERIALS SCIENCE, PAPER & WOOD//CHEMISTRY, PHYSICAL 1084170
41 3       INTERNATIONAL JOURNAL OF PHARMACEUTICS//DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY//PHARMACOLOGY & PHARMACY 99449
1274 2             MICRONEEDLES//TRANSDERMAL DRUG DELIVERY//TRANSDERMAL 8757
320 1                   PENETRATION ENHANCER//PERCUTANEOUS ABSORPTION//TRANSDERMAL 3655

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PENETRATION ENHANCER authKW 1108509 6% 57% 231
2 PERCUTANEOUS ABSORPTION authKW 1095999 7% 48% 274
3 TRANSDERMAL authKW 488871 7% 23% 250
4 SKIN PERMEATION authKW 414040 4% 32% 153
5 TRANSDERMAL DRUG DELIVERY authKW 365214 5% 25% 173
6 PERMEATION ENHANCER authKW 281570 3% 36% 94
7 AZONE authKW 267249 1% 67% 48
8 TRANSDERMAL DELIVERY authKW 253478 4% 22% 138
9 HAIRLESS MOUSE SKIN authKW 215979 1% 63% 41
10 SKIN PERMEABILITY authKW 205754 2% 40% 61

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 64985 76% 0% 2781
2 Chemistry, Medicinal 16380 20% 0% 739
3 Chemistry, Multidisciplinary 4544 25% 0% 900
4 Toxicology 2995 9% 0% 337
5 Dermatology 2946 7% 0% 266
6 Medicine, Legal 34 0% 0% 16
7 Mathematical & Computational Biology 27 1% 0% 30
8 Materials Science, Biomaterials 15 1% 0% 22
9 Chemistry, Applied 9 1% 0% 48
10 Cell & Tissue Engineering 8 0% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT SCI 11 KEYAKIDAI 78414 0% 72% 13
2 CHEM TOXICOL PHARMACOKINET 69551 1% 24% 35
3 THER EUT UNIT 44926 1% 22% 24
4 PHARMACEUT 31319 9% 1% 334
5 TECH RD PHAD 25058 0% 100% 3
6 WELSH PHARM 23660 1% 5% 54
7 PHARM 16923 20% 0% 732
8 NEW ANTIVIRALS ANTINEOPLAST 1M0508 16705 0% 100% 2
9 PHARM POST STUDIES PHARMACEUT TECHNOL 16705 0% 100% 2
10 PHARMACEUT BUSINESSKITA KU 16705 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF PHARMACEUTICS 203804 17% 4% 621
2 DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 74179 6% 4% 219
3 JOURNAL OF PHARMACEUTICAL SCIENCES 61251 8% 3% 287
4 PHARMACEUTICAL RESEARCH 42450 6% 3% 202
5 SKIN PHARMACOLOGY AND PHYSIOLOGY 32004 1% 9% 44
6 JOURNAL OF CONTROLLED RELEASE 26472 4% 2% 154
7 DRUG DELIVERY 18690 1% 4% 54
8 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 18537 2% 2% 91
9 PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 12304 1% 3% 45
10 AAPS PHARMSCITECH 10858 1% 3% 49

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PENETRATION ENHANCER 1108509 6% 57% 231 Search PENETRATION+ENHANCER Search PENETRATION+ENHANCER
2 PERCUTANEOUS ABSORPTION 1095999 7% 48% 274 Search PERCUTANEOUS+ABSORPTION Search PERCUTANEOUS+ABSORPTION
3 TRANSDERMAL 488871 7% 23% 250 Search TRANSDERMAL Search TRANSDERMAL
4 SKIN PERMEATION 414040 4% 32% 153 Search SKIN+PERMEATION Search SKIN+PERMEATION
5 TRANSDERMAL DRUG DELIVERY 365214 5% 25% 173 Search TRANSDERMAL+DRUG+DELIVERY Search TRANSDERMAL+DRUG+DELIVERY
6 PERMEATION ENHANCER 281570 3% 36% 94 Search PERMEATION+ENHANCER Search PERMEATION+ENHANCER
7 AZONE 267249 1% 67% 48 Search AZONE Search AZONE
8 TRANSDERMAL DELIVERY 253478 4% 22% 138 Search TRANSDERMAL+DELIVERY Search TRANSDERMAL+DELIVERY
9 HAIRLESS MOUSE SKIN 215979 1% 63% 41 Search HAIRLESS+MOUSE+SKIN Search HAIRLESS+MOUSE+SKIN
10 SKIN PERMEABILITY 205754 2% 40% 61 Search SKIN+PERMEABILITY Search SKIN+PERMEABILITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JAMPILEK, J , BRYCHTOVA, K , (2012) AZONE ANALOGUES: CLASSIFICATION, DESIGN, AND TRANSDERMAL PENETRATION PRINCIPLES.MEDICINAL RESEARCH REVIEWS. VOL. 32. ISSUE 5. P. 907 -947 120 66% 11
2 SELZER, D , NEUMANN, D , SCHAEFER, UF , (2015) MATHEMATICAL MODELS FOR DERMAL DRUG ABSORPTION.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 11. ISSUE 10. P. 1567 -1583 77 84% 0
3 SELZER, D , ABDEL-MOTTALEB, MMA , HAHN, T , SCHAEFER, UF , NEUMANN, D , (2013) FINITE AND INFINITE DOSING: DIFFICULTIES IN MEASUREMENTS, EVALUATIONS AND PREDICTIONS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 65. ISSUE 2. P. 278-294 95 63% 20
4 ANISSIMOV, YG , JEPPS, OG , DANCIK, Y , ROBERTS, MS , (2013) MATHEMATICAL AND PHARMACOKINETIC MODELLING OF EPIDERMAL AND DERMAL TRANSPORT PROCESSES.ADVANCED DRUG DELIVERY REVIEWS. VOL. 65. ISSUE 2. P. 169-190 65 76% 29
5 BACH, M , LIPPOLD, BC , (1998) PERCUTANEOUS PENETRATION ENHANCEMENT AND ITS QUANTIFICATION.EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. VOL. 46. ISSUE 1. P. 1 -13 98 80% 44
6 MITRAGOTRI, S , ANISSIMOV, YG , BUNGE, AL , FRASCH, HF , GUY, RH , HADGRAFT, J , KASTING, GB , LANE, ME , ROBERTS, MS , (2011) MATHEMATICAL MODELS OF SKIN PERMEABILITY: AN OVERVIEW.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 418. ISSUE 1. P. 115 -129 69 66% 71
7 WILLIAMS, AC , BARRY, BW , (1992) SKIN ABSORPTION ENHANCERS.CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS. VOL. 9. ISSUE 3-4. P. 305-353 109 74% 190
8 SAPRA, B , JAIN, S , TIWARY, AK , (2008) PERCUTANEOUS PERMEATION ENHANCEMENT BY TERPENES: MECHANISTIC VIEW.AAPS JOURNAL. VOL. 10. ISSUE 1. P. 120 -132 70 76% 52
9 WILLIAMS, AC , BARRY, BW , (2004) PENETRATION ENHANCERS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 56. ISSUE 5. P. 603-618 41 84% 797
10 MOSSA, GP , SUN, Y , WILKINSON, SC , DAVEY, N , ADAMS, R , MARTIN, GP , PRAPOPOPOLOU, M , BROWN, MB , (2011) THE APPLICATION AND LIMITATIONS OF MATHEMATICAL MODELLING IN THE PREDICTION OF PERMEABILITY ACROSS MAMMALIAN SKIN AND POLYDIMETHYLSILOXANE MEMBRANES.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 63. ISSUE 11. P. 1411 -1427 68 76% 8

Classes with closest relation at Level 1


Rank Class id link
1 23211 SKIN BLANCHING//HUMAN SKIN BLANCHING ASSAY//ENHANCER CELL
2 7454 IONTOPHORESIS//SONOPHORESIS//REVERSE IONTOPHORESIS
3 19539 EXPT PL CUTANEOUS PHYSIOL//FOLLICULAR PENETRATION//HAIR FOLLICLE
4 13051 MICROEMULSION//NANOEMULSION//PSEUDO TERNARY PHASE DIAGRAM
5 22776 JET FUEL//JP 8 JET FUEL//JP 8
6 1748 STRATUM CORNEUM//TRANSEPIDERMAL WATER LOSS//STRATUM CORNEUM LIPIDS
7 30038 MULTILAYER MEMBRANE SYSTEM//OPTO THERMAL RADIOMETRY//ECOLE SCI PL TANGER
8 6214 NIOSOMES//ETHOSOMES//PRONIOSOMES
9 18146 DICLOFENAC EPOLAMINE//TOPICAL NSAIDS//DICLOFENAC N 2 HYDROXYETHYLPYRROLIDINE
10 24758 AHH INDUCTION//BADEN WUERTTEMBERG HESSE//BIOCHEMICAL SKIN BARRIER

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