Class information for:
Level 1: RESIDUAL DNA//RESIDUAL HOST CELL DNA//DNA ONCOGENICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
30267 171 27.4 51%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
373 3       ENDOGENOUS RETROVIRUS//VIROLOGY//JOURNAL OF VIROLOGY 32972
3655 2             RESIDUAL DNA//AFFINITY RESINS//NONSPECIFIC BINDING PROTEINS 1185
30267 1                   RESIDUAL DNA//RESIDUAL HOST CELL DNA//DNA ONCOGENICITY 171

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RESIDUAL DNA authKW 1269830 5% 89% 8
2 RESIDUAL HOST CELL DNA authKW 401781 2% 75% 3
3 DNA ONCOGENICITY authKW 357140 1% 100% 2
4 ECT ANIM PATHOGEN MICROORGANISMS address 357140 1% 100% 2
5 HISTORY OF VACCINES authKW 357140 1% 100% 2
6 HOST RESIDUAL DNA authKW 357140 1% 100% 2
7 RESIDUAL HOST DNA authKW 357140 1% 100% 2
8 MERCK THER EUT address 229587 2% 43% 3
9 3D VIRUS CULTURE authKW 178570 1% 100% 1
10 ANIMAL CELL SUBSTRATE authKW 178570 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOLOGY, MISCELLANEOUS 14018 6% 1% 11
2 Biochemical Research Methods 1458 31% 0% 53
3 Biotechnology & Applied Microbiology 997 33% 0% 56
4 Pharmacology & Pharmacy 325 27% 0% 46
5 Virology 269 10% 0% 17
6 CYTOLOGY & HISTOLOGY 91 1% 0% 2
7 Biochemistry & Molecular Biology 87 22% 0% 38
8 Medicine, Research & Experimental 73 9% 0% 15
9 Chemistry, Analytical 59 9% 0% 16
10 Biology 58 6% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ECT ANIM PATHOGEN MICROORGANISMS 357140 1% 100% 2
2 MERCK THER EUT 229587 2% 43% 3
3 BIOASSAY METHODS DEV PHARMACEUT DEV MFG SCI 178570 1% 100% 1
4 BIOL CONTROLS IMMUNOL MED BIOL SAFETY 178570 1% 100% 1
5 BIOPROC DEV BIOL VACCINES 178570 1% 100% 1
6 DISCOVERY BIOL SAFETY ASSESSMENT 178570 1% 100% 1
7 EFFECT ASSESSMENT 178570 1% 100% 1
8 MERCK S WP53C350 178570 1% 100% 1
9 MERCK VACCINOL 178570 1% 100% 1
10 PROD HEPATITIS B 178570 1% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOLOGICALS 82075 15% 2% 25
2 JOURNAL OF BIOLOGICAL STANDARDIZATION 52296 6% 3% 11
3 DEVELOPMENTS IN BIOLOGICAL STANDARDIZATION 19791 5% 1% 8
4 DEVELOPMENTS IN BIOLOGICALS 5491 1% 2% 2
5 BIOTECHNIQUES 2938 6% 0% 10
6 PHARMACEUTICAL SCIENCE & TECHNOLOGY TODAY 2444 1% 1% 1
7 JOURNAL OF HUMAN VIROLOGY 1858 1% 1% 1
8 BIOPHARM-THE TECHNOLOGY & BUSINESS OF BIOPHARMACEUTICALS 1784 1% 1% 1
9 JOURNAL OF PARENTERAL SCIENCE AND TECHNOLOGY 1499 1% 1% 1
10 HUMAN GENE THERAPY METHODS 1074 1% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RESIDUAL DNA 1269830 5% 89% 8 Search RESIDUAL+DNA Search RESIDUAL+DNA
2 RESIDUAL HOST CELL DNA 401781 2% 75% 3 Search RESIDUAL+HOST+CELL+DNA Search RESIDUAL+HOST+CELL+DNA
3 DNA ONCOGENICITY 357140 1% 100% 2 Search DNA+ONCOGENICITY Search DNA+ONCOGENICITY
4 HISTORY OF VACCINES 357140 1% 100% 2 Search HISTORY+OF+VACCINES Search HISTORY+OF+VACCINES
5 HOST RESIDUAL DNA 357140 1% 100% 2 Search HOST+RESIDUAL+DNA Search HOST+RESIDUAL+DNA
6 RESIDUAL HOST DNA 357140 1% 100% 2 Search RESIDUAL+HOST+DNA Search RESIDUAL+HOST+DNA
7 3D VIRUS CULTURE 178570 1% 100% 1 Search 3D+VIRUS+CULTURE Search 3D+VIRUS+CULTURE
8 ANIMAL CELL SUBSTRATE 178570 1% 100% 1 Search ANIMAL+CELL+SUBSTRATE Search ANIMAL+CELL+SUBSTRATE
9 ASBV VIROID 178570 1% 100% 1 Search ASBV+VIROID Search ASBV+VIROID
10 BIOTECHNOLOGY DRUG 178570 1% 100% 1 Search BIOTECHNOLOGY+DRUG Search BIOTECHNOLOGY+DRUG

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ANDRE, M , REGHIN, S , BOUSSARD, E , LEMPEREUR, L , MAISONNEUVE, S , (2016) UNIVERSAL REAL-TIME PCR ASSAY FOR QUANTITATION AND SIZE EVALUATION OF RESIDUAL CELL DNA IN HUMAN VIRAL VACCINES.BIOLOGICALS. VOL. 44. ISSUE 3. P. 139 -149 16 38% 0
2 CHANG, JT , CHEN, YC , CHOU, YC , WANG, SR , (2014) QUANTITATIVE DETECTION OF RESIDUAL PORCINE HOST CELL DNA BY REAL-TIME PCR.BIOLOGICALS. VOL. 42. ISSUE 2. P. 74-78 10 38% 2
3 LOKTEFF, M , KLINGUER-HAMOUR, C , JULIEN, E , PICOT, D , LANNES, L , NGUYEN, T , BONNEFOY, JY , BECK, A , (2001) RESIDUAL DNA QUANTIFICATION IN CLINICAL BATCHES OF BBG2NA, A RECOMBINANT SUBUNIT VACCINE AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS.BIOLOGICALS. VOL. 29. ISSUE 2. P. 123-132 10 53% 7
4 (1998) REQUIREMENTS FOR THE USE OF ANIMAL CELLS AS IN VITRO SUBSTRATES FOR THE PRODUCTION OF BIOLOGICALS.WHO EXPERT COMMITTEE ON BIOLOGICAL STANDARDIZATION - FORTY-SEVENTH REPORT. VOL. 878. ISSUE . P. 19-56 8 67% 0
5 GRACHEV, V , MAGRATH, D , GRIFFITHS, E , (1998) WHO REQUIREMENTS FOR THE USE OF ANIMAL CELLS AS IN VITRO SUBSTRATES FOR THE PRODUCTION OF BIOLOGICALS - (REQUIREMENTS FOR BIOLOGICAL SUBSTANCES N DEGREES 50).SAFETY OF BIOLOGICAL PRODUCTS PREPARED FROM MAMMALIAN CELL CULTURE. VOL. 93. ISSUE . P. 141 -171 8 67% 0
6 ASSAF, SLMR , YOKOMIZO, AY , SERAPICOS, ED , GALLINA, NMF , MACHADO, LD , (1997) TUMORIGENICITY TESTING OF VERO CELLS.ARQUIVOS DE BIOLOGIA E TECNOLOGIA. VOL. 40. ISSUE 3. P. 596 -600 5 100% 1
7 YANG, H , WEI, ZP , SCHENERMAN, M , (2015) A STATISTICAL APPROACH TO DETERMINING CRITICALITY OF RESIDUAL HOST CELL DNA.JOURNAL OF BIOPHARMACEUTICAL STATISTICS. VOL. 25. ISSUE 2. P. 234 -246 6 50% 0
8 RIGGIN, A , DAVIS, GC , COPMANN, TL , (1996) REASSESSING THE CONTROL OF RESIDUAL DNA IN BIOPHARMACEUTICALS.BIOPHARM-THE TECHNOLOGY & BUSINESS OF BIOPHARMACEUTICALS. VOL. 9. ISSUE 9. P. 36-& 11 39% 6
9 FERRO, S , FABRE, I , CHENIVESSE, X , (2016) OPTIMIZING A METHOD FOR THE QUANTIFICATION BY QUANTITATIVE REAL-TIME POLYMERASE CHAIN REACTION OF HOST CELL DNA IN PLASMID VECTOR BATCHES USED IN HUMAN GENE THERAPY.HUMAN GENE THERAPY METHODS. VOL. 27. ISSUE 4. P. 159 -170 6 40% 0
10 SHEN, X , CHEN, XM , TABOR, DE , LIU, Y , ALBARGHOUTHI, M , ZHANG, YF , GALINSKI, MS , (2013) SIZE ANALYSIS OF RESIDUAL HOST CELL DNA IN CELL CULTURE-PRODUCED VACCINES BY CAPILLARY GEL ELECTROPHORESIS.BIOLOGICALS. VOL. 41. ISSUE 3. P. 201-208 7 33% 6

Classes with closest relation at Level 1


Rank Class id link
1 28468 STOP CODON OPTIMIZATION//TAA STOP CODON//VOPROSY VIRUSOLOGII
2 27287 DIGITAL PCR//DROPLET DIGITAL PCR//ACTIVITY BASED BIOMARKERS
3 8820 ADV BIOCHEM ENGN//HOST CELL PROTEINS//HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY
4 35034 HUMAN SKIN CARCINOGENESIS MODEL//NEONATAL FORESKIN GRAFT//RECONSTRUCTS
5 7191 HEMAGGLUTININ//INFLUENZA VIRUS//CHAIR BIOPROC ENGN
6 35209 ADSORPTIVE SIZE EXCLUSION CHROMATOGRAPHY//ANS TNS//CELL SURFACE OLIGOSACCHARIDE
7 24096 MYCOPLASMA DETECTION//MYCOPLASMA CONTAMINATION//MYCOPLASMA
8 23924 VOLTAGE GRADIENT GEL ELECTROPHORESIS//VOLTAGE GRADIENT ELECTROPHORESIS//ACHE MESSENGER RNA
9 25317 VIRUS FILTRATION//VIRAL CLEARANCE//XMULV
10 27547 THIOTEPA//THIOTEPA MERCAPTURATE//N N N TRIETHYLENEPHOSPHORAMIDE

Go to start page