Class information for:
Level 1: ADV BIOCHEM ENGN//HOST CELL PROTEINS//HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8820 1213 31.6 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
12 4 POLYMER SCIENCE//MATERIALS SCIENCE, PAPER & WOOD//CHEMISTRY, PHYSICAL 1084170
582 3       AQUEOUS TWO PHASE SYSTEMS//SIMULATED MOVING BED//JOURNAL OF CHROMATOGRAPHY A 15824
890 2             SIMULATED MOVING BED//EXPANDED BED ADSORPTION//SIMULATED MOVING BED CHROMATOGRAPHY 11401
8820 1                   ADV BIOCHEM ENGN//HOST CELL PROTEINS//HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY 1213

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADV BIOCHEM ENGN address 755195 10% 25% 118
2 HOST CELL PROTEINS authKW 719743 4% 62% 46
3 HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY authKW 462704 2% 74% 25
4 MULTIMODAL CHROMATOGRAPHY authKW 406093 2% 73% 22
5 PROTEIN A CHROMATOGRAPHY authKW 398896 2% 59% 27
6 HIGH THROUGHPUT PROCESS DEVELOPMENT authKW 290975 1% 68% 17
7 PURIFICAT PROC DEV address 242080 2% 42% 23
8 ANTIBODY PURIFICATION authKW 241858 3% 31% 31
9 ULTRA SCALE DOWN authKW 230129 1% 57% 16
10 MIXED MODE CHROMATOGRAPHY authKW 212977 3% 26% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biotechnology & Applied Microbiology 12575 43% 0% 523
2 Biochemical Research Methods 10065 31% 0% 371
3 Chemistry, Analytical 4778 28% 0% 334
4 Engineering, Chemical 1177 14% 0% 171
5 Food Science & Technology 476 8% 0% 100
6 Biophysics 168 5% 0% 65
7 Pharmacology & Pharmacy 141 9% 0% 108
8 Biochemistry & Molecular Biology 111 13% 0% 153
9 Engineering, Environmental 12 1% 0% 17
10 Chemistry, Multidisciplinary 9 5% 0% 63

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADV BIOCHEM ENGN 755195 10% 25% 118
2 PURIFICAT PROC DEV 242080 2% 42% 23
3 BIOCHEM ENGN 104851 12% 3% 145
4 OCEANSIDE PROC DEV 80548 0% 80% 4
5 EARLY STAGE PURIFICAT 78658 0% 63% 5
6 PROC BIOCHEM 77081 1% 44% 7
7 PURIFICAT DEV 55092 1% 24% 9
8 SECT BIOMOL SEPARAT ENGN 4 50745 1% 18% 11
9 COMMERCIAL PROC DEV 50344 0% 100% 2
10 EARLY LATE STAGE PURIFICAT 50344 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHARM INTERNATIONAL 135101 4% 10% 53
2 BIOTECHNOLOGY PROGRESS 47969 8% 2% 94
3 BIOPHARM-THE TECHNOLOGY & BUSINESS OF BIOPHARMACEUTICALS 42518 1% 13% 13
4 BIOTECHNOLOGY AND BIOENGINEERING 31472 10% 1% 121
5 JOURNAL OF MOLECULAR RECOGNITION 26714 3% 3% 36
6 JOURNAL OF CHROMATOGRAPHY A 25438 14% 1% 165
7 BIOTECHNOLOGY JOURNAL 15939 2% 3% 25
8 BIOPHARM-THE APPLIED TECHNOLOGIES OF BIOPHARMACEUTICAL DEVELOPMENT 14202 1% 6% 10
9 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 11117 6% 1% 73
10 GENETIC ENGINEERING NEWS 8290 1% 2% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HOST CELL PROTEINS 719743 4% 62% 46 Search HOST+CELL+PROTEINS Search HOST+CELL+PROTEINS
2 HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY 462704 2% 74% 25 Search HYDROPHOBIC+CHARGE+INDUCTION+CHROMATOGRAPHY Search HYDROPHOBIC+CHARGE+INDUCTION+CHROMATOGRAPHY
3 MULTIMODAL CHROMATOGRAPHY 406093 2% 73% 22 Search MULTIMODAL+CHROMATOGRAPHY Search MULTIMODAL+CHROMATOGRAPHY
4 PROTEIN A CHROMATOGRAPHY 398896 2% 59% 27 Search PROTEIN+A+CHROMATOGRAPHY Search PROTEIN+A+CHROMATOGRAPHY
5 HIGH THROUGHPUT PROCESS DEVELOPMENT 290975 1% 68% 17 Search HIGH+THROUGHPUT+PROCESS+DEVELOPMENT Search HIGH+THROUGHPUT+PROCESS+DEVELOPMENT
6 ANTIBODY PURIFICATION 241858 3% 31% 31 Search ANTIBODY+PURIFICATION Search ANTIBODY+PURIFICATION
7 ULTRA SCALE DOWN 230129 1% 57% 16 Search ULTRA+SCALE+DOWN Search ULTRA+SCALE+DOWN
8 MIXED MODE CHROMATOGRAPHY 212977 3% 26% 32 Search MIXED+MODE+CHROMATOGRAPHY Search MIXED+MODE+CHROMATOGRAPHY
9 BIOPHARMACEUTICAL MANUFACTURE 169905 1% 75% 9 Search BIOPHARMACEUTICAL+MANUFACTURE Search BIOPHARMACEUTICAL+MANUFACTURE
10 THIOPHILIC ADSORPTION 161096 1% 80% 8 Search THIOPHILIC+ADSORPTION Search THIOPHILIC+ADSORPTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, RZ , LIN, DQ , CHU, WN , ZHANG, QL , YAO, SJ , (2016) NEW TETRAPEPTIDE LIGANDS DESIGNED FOR ANTIBODY PURIFICATION WITH BIOMIMETIC CHROMATOGRAPHY: MOLECULAR SIMULATION AND EXPERIMENTAL VALIDATION.BIOCHEMICAL ENGINEERING JOURNAL. VOL. 114. ISSUE . P. 194 -204 39 80% 0
2 TONG, HF , LIN, DQ , CHU, WN , ZHANG, QL , GAO, D , WANG, RZ , YAO, SJ , (2016) MULTIMODAL CHARGE-INDUCTION CHROMATOGRAPHY FOR ANTIBODY PURIFICATION.JOURNAL OF CHROMATOGRAPHY A. VOL. 1429. ISSUE . P. 258 -264 34 79% 1
3 LUO, YD , ZHANG, QL , YUAN, XM , SHI, W , YAO, SJ , LIN, DQ , (2017) SELECTIVITY EVALUATION AND SEPARATION OF HUMAN IMMUNOGLOBULIN G, FAB AND FC FRAGMENTS WITH MIXED-MODE RESINS.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 1040. ISSUE . P. 105 -111 30 88% 0
4 LIN, CP , SAITO, K , BOYSEN, RI , CAMPI, EM , HEARN, MTW , (2016) STATIC AND DYNAMIC BINDING BEHAVIOR OF AN IGG2 MONOCLONAL ANTIBODY WITH SEVERAL NEW MIXED MODE AFFINITY ADSORBENTS.SEPARATION AND PURIFICATION TECHNOLOGY. VOL. 163. ISSUE . P. 199 -205 30 81% 1
5 NAIK, AD , MENEGATTI, S , GURGEL, PV , CARBONELL, RG , (2011) PERFORMANCE OF HEXAMER PEPTIDE LIGANDS FOR AFFINITY PURIFICATION OF IMMUNOGLOBULIN G FROM COMMERCIAL CELL CULTURE MEDIA.JOURNAL OF CHROMATOGRAPHY A. VOL. 1218. ISSUE 13. P. 1691-1700 29 91% 32
6 CHIVERTON, LM , EVANS, C , PANDHAL, J , LANDELS, AR , REES, BJ , LEVISON, PR , WRIGHT, PC , SMALES, CM , (2016) QUANTITATIVE DEFINITION AND MONITORING OF THE HOST CELL PROTEIN PROTEOME USING ITRAQ - A STUDY OF AN INDUSTRIAL MAB PRODUCING CHO-S CELL LINE.BIOTECHNOLOGY JOURNAL. VOL. 11. ISSUE 8. P. 1014 -1024 30 71% 1
7 WANG, RZ , LIN, DQ , TONG, HF , LU, HL , YAO, SJ , (2013) EVALUATION OF MIXED-MODE CHROMATOGRAPHIC RESINS FOR SEPARATING IGG FROM SERUM ALBUMIN CONTAINING FEEDSTOCK.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 936. ISSUE . P. 33-41 31 74% 8
8 HOGWOOD, CEM , BRACEWELL, DG , SMALES, CM , (2014) MEASUREMENT AND CONTROL OF HOST CELL PROTEINS (HCPS) IN CHO CELL BIOPROCESSES.CURRENT OPINION IN BIOTECHNOLOGY. VOL. 30. ISSUE . P. 153 -160 32 68% 6
9 GAGNON, P , (2012) TECHNOLOGY TRENDS IN ANTIBODY PURIFICATION.JOURNAL OF CHROMATOGRAPHY A. VOL. 1221. ISSUE . P. 57 -70 66 27% 70
10 LIN, CP , BOYSEN, RI , CAMPI, EM , SAITO, K , HEARN, MTW , (2016) STUDIES ON THE BINDING SITES OF IGG2 MONOCLONAL ANTIBODIES RECOGNIZED BY TERPYRIDINE-BASED AFFINITY LIGANDS.JOURNAL OF MOLECULAR RECOGNITION. VOL. 29. ISSUE 7. P. 334 -342 32 60% 1

Classes with closest relation at Level 1


Rank Class id link
1 6943 DISPLACEMENT CHROMATOGRAPHY//BIOCHEM PROC//ION EXCHANGE CHROMATOGRAPHY
2 25317 VIRUS FILTRATION//VIRAL CLEARANCE//XMULV
3 21184 EXPANDED BED ADSORPTION//EXPANDED BED//FLUIDIZED BED ADSORPTION
4 12955 MEMBRANE CHROMATOGRAPHY//AFFINITY MEMBRANE//BIOCHEM PROC BIOMAT
5 18774 TIIV DOPED CALCIUM HYDROXYAPATITE//ENGN MAT SCI ENGN KITA KU//IGG BOVINE
6 27840 CHROMATOFOCUSING//ACID BASE RESIDUES//INDUCED PH GRADIENTS
7 18731 BIOMIMETIC DYE//TRIAZINE DYES//BEAD CELLULOSE
8 13409 STAPHYLOCOCCAL PROTEIN A//PROTEIN L//PROTEIN G
9 12771 CRYOGEL//CIBACRON BLUE F3GA//COMPOSITE CRYOGEL
10 14520 SCALE DOWN//SHAKE FLASK//AVT BIOCHEM ENGN

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