Class information for:
Level 1: C2 DEFICIENCY//COMPLEMENT GENETICS//COMPLEMENT AND INFLAMMATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2629 2191 34.8 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
350 3       COMPLEMENT//MANNOSE BINDING LECTIN//IMMUNOLOGY 35656
363 2             COMPLEMENT//MANNOSE BINDING LECTIN//PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 17354
2629 1                   C2 DEFICIENCY//COMPLEMENT GENETICS//COMPLEMENT AND INFLAMMATION 2191

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 C2 DEFICIENCY authKW 123939 1% 68% 13
2 COMPLEMENT GENETICS authKW 107187 0% 77% 10
3 COMPLEMENT AND INFLAMMATION journal 106177 1% 30% 25
4 C4 authKW 100048 2% 19% 38
5 C3 authKW 68973 2% 11% 46
6 C3 CONVERTASE authKW 65400 1% 36% 13
7 COMPLEMENT COMPONENT C4 authKW 59448 0% 53% 8
8 RCCX MODULES authKW 55740 0% 100% 4
9 COMPLEMENT authKW 53076 6% 3% 139
10 C4B authKW 49538 0% 44% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Immunology 24955 51% 0% 1116
2 Genetics & Heredity 2015 14% 0% 301
3 Biochemistry & Molecular Biology 1685 26% 0% 572
4 Rheumatology 670 3% 0% 76
5 Pathology 415 5% 0% 100
6 Biology 209 3% 0% 76
7 Cell Biology 201 7% 0% 153
8 Biochemical Research Methods 189 4% 0% 89
9 Medicine, Research & Experimental 164 4% 0% 97
10 Urology & Nephrology 81 3% 0% 56

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRP INFLAMMAT BIOL IMMUNGENOM 27870 0% 100% 2
2 AURORA HOSP INFECT DIS 13935 0% 100% 1
3 BEYSEHIR YOLU 13935 0% 100% 1
4 BIOCHEM BLOOD BANK 13935 0% 100% 1
5 C MONDINO FDN IRCCS NEUROL 13935 0% 100% 1
6 CLSI CLIN IMMUNOPATHOL 13935 0% 100% 1
7 FOR ERGRP PRIMATENGENET 13935 0% 100% 1
8 GEN PATHOL CORSO TUKORY 211 13935 0% 100% 1
9 GENET GENE TRANSFER CORE 13935 0% 100% 1
10 HAUTKLIN 1 13935 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COMPLEMENT AND INFLAMMATION 106177 1% 30% 25
2 EXPERIMENTAL AND CLINICAL IMMUNOGENETICS 39625 2% 8% 36
3 IMMUNOGENETICS 27554 4% 2% 94
4 COMPLEMENT 24376 0% 25% 7
5 MOLECULAR IMMUNOLOGY 15238 4% 1% 88
6 JOURNAL OF IMMUNOLOGY 9625 9% 0% 194
7 JOURNAL OF IMMUNOGENETICS 9179 1% 4% 18
8 HUMAN HEREDITY 6452 1% 2% 31
9 IMMUNOBIOLOGY 4728 2% 1% 33
10 SCANDINAVIAN JOURNAL OF IMMUNOLOGY 4319 2% 1% 42

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 C2 DEFICIENCY 123939 1% 68% 13 Search C2+DEFICIENCY Search C2+DEFICIENCY
2 COMPLEMENT GENETICS 107187 0% 77% 10 Search COMPLEMENT+GENETICS Search COMPLEMENT+GENETICS
3 C4 100048 2% 19% 38 Search C4 Search C4
4 C3 68973 2% 11% 46 Search C3 Search C3
5 C3 CONVERTASE 65400 1% 36% 13 Search C3+CONVERTASE Search C3+CONVERTASE
6 COMPLEMENT COMPONENT C4 59448 0% 53% 8 Search COMPLEMENT+COMPONENT+C4 Search COMPLEMENT+COMPONENT+C4
7 RCCX MODULES 55740 0% 100% 4 Search RCCX+MODULES Search RCCX+MODULES
8 COMPLEMENT 53076 6% 3% 139 Search COMPLEMENT Search COMPLEMENT
9 C4B 49538 0% 44% 8 Search C4B Search C4B
10 COBRA VENOM FACTOR 48843 1% 22% 16 Search COBRA+VENOM+FACTOR Search COBRA+VENOM+FACTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BLANCHONG, CA , CHUNG, EK , RUPERT, KL , YANG, Y , YANG, ZY , ZHOU, B , MOULDS, JM , YU, CY , (2001) GENETIC, STRUCTURAL AND FUNCTIONAL DIVERSITIES OF HUMAN COMPLEMENT COMPONENTS C4A AND C4B AND THEIR MOUSE HOMOLOGUES, SLP AND C4.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 1. ISSUE 3. P. 365 -392 139 87% 73
2 YU, CY , CHUNG, EK , YANG, Y , BLANCHONG, CA , JACOBSEN, N , SAXENA, K , YANG, ZY , MILLER, W , VARGA, L , FUST, G , (2003) DANCING WITH COMPLEMENT C4 AND THE RP-C4-CYP21-TNX (RCCX) MODULES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 75. VOL. 75. ISSUE . P. 217 -292 157 68% 30
3 LAW, SKA , DODDS, AW , (1997) THE INTERNAL THIOESTER AND THE COVALENT BINDING PROPERTIES OF THE COMPLEMENT PROTEINS C3 AND C4.PROTEIN SCIENCE. VOL. 6. ISSUE 2. P. 263-274 56 79% 171
4 VOGEL, CW , FRITZINGER, DC , (2010) COBRA VENOM FACTOR: STRUCTURE, FUNCTION, AND HUMANIZATION FOR THERAPEUTIC COMPLEMENT DEPLETION.TOXICON. VOL. 56. ISSUE 7. P. 1198 -1222 58 50% 37
5 HEW, BE , WEHRHAHN, D , FRITZINGER, DC , VOGEL, CW , (2012) HYBRID PROTEINS OF COBRA VENOM FACTOR AND COBRA C3: TOOLS TO IDENTIFY FUNCTIONALLY IMPORTANT REGIONS IN COBRA VENOM FACTOR.TOXICON. VOL. 60. ISSUE 4. P. 632 -647 34 87% 1
6 WOUTERS, D , VAN SCHOUWENBURG, P , VAN DER HORST, A , DE BOER, M , SCHOONEMAN, D , KUIJPERS, TW , AARDEN, LA , HAMANN, D , (2009) HIGH-THROUGHPUT ANALYSIS OF THE C4 POLYMORPHISM BY A COMBINATION OF MLPA AND ISOTYPE-SPECIFIC ELISA'S.MOLECULAR IMMUNOLOGY. VOL. 46. ISSUE 4. P. 592-600 35 85% 10
7 YU, CY , (1998) MOLECULAR GENETICS OF THE HUMAN MHC COMPLEMENT GENE CLUSTER.EXPERIMENTAL AND CLINICAL IMMUNOGENETICS. VOL. 15. ISSUE 4. P. 213-230 60 67% 34
8 XU, YY , NARAYANA, SVL , VOLANAKIS, JE , (2001) STRUCTURAL BIOLOGY OF THE ALTERNATIVE PATHWAY CONVERTASE.IMMUNOLOGICAL REVIEWS. VOL. 180. ISSUE . P. 123-135 54 65% 49
9 YANG, Y , CHUNG, EK , ZHOU, B , BLANCHONG, CA , YU, CY , FUST, G , KOVACS, M , VATAY, A , SZALAI, C , KARADI, I , ET AL (2003) DIVERSITY IN INTRINSIC STRENGTHS OF THE HUMAN COMPLEMENT SYSTEM: SERUM C4 PROTEIN CONCENTRATIONS CORRELATE WITH C4 GENE SIZE AND POLYGENIC VARIATIONS, HEMOLYTIC ACTIVITIES, AND BODY MASS INDEX.JOURNAL OF IMMUNOLOGY. VOL. 171. ISSUE 5. P. 2734 -2745 41 75% 44
10 WU, YL , YANG, Y , CHUNG, EK , ZHOU, B , KITZMILLER, KJ , SAVELLI, SL , NAGARAJA, HN , BIRMINGHAM, DJ , TSAO, BP , ROVIN, BH , ET AL (2008) PHENOTYPES, GENOTYPES AND DISEASE SUSCEPTIBILITY ASSOCIATED WITH GENE COPY NUMBER VARIATIONS: COMPLEMENT C4 CNVS IN EUROPEAN AMERICAN HEALTHY SUBJECTS AND THOSE WITH SYSTEMIC LUPUS ERYTHEMATOSUS.CYTOGENETIC AND GENOME RESEARCH. VOL. 123. ISSUE 1-4. P. 131-141 36 68% 25

Classes with closest relation at Level 1


Rank Class id link
1 23444 MOL IMMUNOGENET GRP//CYTOGENET MUTAGENESIS//RUDBECK S
2 7487 PROPERDIN//COMPLEMENT DEFICIENCY//C7
3 9804 COMPLEMENT RECEPTOR 1//COMPLEMENT RECEPTOR TYPE 1//CR1
4 30260 CAMEL COMPLEMENT//AP DEPENDENT PHAGOCYTOSIS//AP LYTIC ACTIVITY
5 4973 ATYPICAL HEMOLYTIC UREMIC SYNDROME//FACTOR H//ECULIZUMAB
6 36876 C2 FUNCTIONAL ASSAY//C4 SYNTHESIS//CHOLINE PHOSPHOLIPID METABOLITES
7 14680 COELOMOCYTES//THIOESTER CONTAINING PROTEIN TEP//COMPLEMENT LYTIC PATHWAY
8 7412 C1Q//ANTI C1Q ANTIBODIES//C1Q DEFICIENCY
9 3467 C5A//C5A RECEPTOR//ANAPHYLATOXIN
10 9963 CD21//CR2//C3D

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