Class information for:
Level 1: CD28//COSTIMULATION//B7

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2395 2259 43.9 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
919 2             PD L1//PD 1//FOXP3 11160
2395 1                   CD28//COSTIMULATION//B7 2259

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CD28 authKW 692720 8% 27% 187
2 COSTIMULATION authKW 533089 10% 17% 237
3 B7 authKW 361054 3% 40% 67
4 CD80 authKW 307443 4% 26% 86
5 CTLA4IG authKW 276100 3% 36% 57
6 CD86 authKW 240468 3% 24% 75
7 CTLA 4 authKW 200638 5% 12% 120
8 COSTIMULATORY MOLECULES authKW 171753 4% 13% 98
9 B7 1 authKW 154137 2% 31% 37
10 B7 2 authKW 140756 1% 42% 25

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Immunology 55107 74% 0% 1662
2 Transplantation 5099 10% 0% 230
3 Medicine, Research & Experimental 853 8% 0% 188
4 Surgery 443 10% 0% 218
5 Cell Biology 290 8% 0% 177
6 Allergy 240 2% 0% 39
7 Hematology 197 4% 0% 83
8 Rheumatology 83 1% 0% 32
9 Biochemistry & Molecular Biology 46 9% 0% 200
10 Dermatology 14 1% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL SIGNALLING SECT 84583 1% 48% 13
2 STELLAR CHANCE S 901 42232 0% 63% 5
3 IMMUNOGENET TRANSPLANTAT 40012 1% 15% 20
4 SECT IMMUNOPATHOGENESIS 36514 0% 27% 10
5 COMM IMMUNOL 34532 2% 7% 38
6 AOR 11 27031 0% 100% 2
7 CHAIR P PHYSIOL 27031 0% 100% 2
8 FORHUMANTECH CO LTD 27031 0% 100% 2
9 PHARMACOKINET PHARMACODYNAM S 27031 0% 100% 2
10 SECT TOXICOL BIOMED 22519 0% 33% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF IMMUNOLOGY 53899 20% 1% 461
2 EUROPEAN JOURNAL OF IMMUNOLOGY 16223 6% 1% 126
3 INTERNATIONAL IMMUNOLOGY 11643 3% 1% 59
4 JOURNAL OF EXPERIMENTAL MEDICINE 8244 4% 1% 87
5 IMMUNITY 5340 2% 1% 37
6 TRANSPLANTATION 4245 3% 0% 77
7 CELLULAR IMMUNOLOGY 3755 2% 1% 47
8 TRANSPLANTATION PROCEEDINGS 3230 4% 0% 100
9 IMMUNOLOGIC RESEARCH 3120 1% 1% 20
10 IMMUNOLOGY 2918 2% 1% 44

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CD28 692720 8% 27% 187 Search CD28 Search CD28
2 COSTIMULATION 533089 10% 17% 237 Search COSTIMULATION Search COSTIMULATION
3 B7 361054 3% 40% 67 Search B7 Search B7
4 CD80 307443 4% 26% 86 Search CD80 Search CD80
5 CTLA4IG 276100 3% 36% 57 Search CTLA4IG Search CTLA4IG
6 CD86 240468 3% 24% 75 Search CD86 Search CD86
7 CTLA 4 200638 5% 12% 120 Search CTLA+4 Search CTLA+4
8 COSTIMULATORY MOLECULES 171753 4% 13% 98 Search COSTIMULATORY+MOLECULES Search COSTIMULATORY+MOLECULES
9 B7 1 154137 2% 31% 37 Search B7+1 Search B7+1
10 B7 2 140756 1% 42% 25 Search B7+2 Search B7+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LENSCHOW, DJ , WALUNAS, TL , BLUESTONE, JA , (1996) CD28/B7 SYSTEM OF T CELL COSTIMULATION.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 14. ISSUE . P. 233-258 85 79% 1911
2 GREENFIELD, EA , NGUYEN, KA , KUCHROO, VK , (1998) CD28/B7 COSTIMULATION: A REVIEW.CRITICAL REVIEWS IN IMMUNOLOGY. VOL. 18. ISSUE 5. P. 389 -418 143 64% 295
3 SALOMON, B , BLUESTONE, JA , (2001) COMPLEXITIES OF CD28/B7: CTLA-4 COSTIMULATORY PATHWAYS IN AUTOIMMUNITY AND TRANSPLANTATION.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 19. ISSUE . P. 225 -252 98 63% 722
4 RUDD, CE , TAYLOR, A , SCHNEIDER, H , (2009) CD28 AND CTLA-4 CORECEPTOR EXPRESSION AND SIGNAL TRANSDUCTION.IMMUNOLOGICAL REVIEWS. VOL. 229. ISSUE . P. 12-26 94 56% 249
5 CHAMBERS, CA , KUHNS, MS , EGEN, JG , ALLISON, JP , (2001) CTLA-4-MEDIATED INHIBITION IN REGULATION OF T CELL RESPONSES: MECHANISMS AND MANIPULATION IN TUMOR IMMUNOTHERAPY.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 19. ISSUE . P. 565 -594 88 69% 474
6 ALEGRE, ML , FALLARINO, F , (2006) MECHANISMS OF CTLA-4-IG IN TOLERANCE INDUCTION.CURRENT PHARMACEUTICAL DESIGN. VOL. 12. ISSUE 2. P. 149-160 109 66% 38
7 SLAVIK, JM , HUTCHCROFT, JE , BIERER, BE , (1999) CD28/CTLA-4 AND CD80/CD86 FAMILIES - SIGNALING AND FUNCTION.IMMUNOLOGIC RESEARCH. VOL. 19. ISSUE 1. P. 1 -24 122 65% 110
8 BOUR-JORDAN, H , ESENSTEN, JH , MARTINEZ-LLORDELLA, M , PENARANDA, C , STUMPF, M , BLUESTONE, JA , (2011) INTRINSIC AND EXTRINSIC CONTROL OF PERIPHERAL T-CELL TOLERANCE BY COSTIMULATORY MOLECULES OF THE CD28/B7 FAMILY.IMMUNOLOGICAL REVIEWS. VOL. 241. ISSUE . P. 180 -205 104 39% 154
9 JUNE, CH , BLUESTONE, JA , NADLER, LM , THOMPSON, CB , (1994) THE B7 AND CD28 RECEPTOR FAMILIES.IMMUNOLOGY TODAY. VOL. 15. ISSUE 7. P. 321-331 61 70% 1219
10 HARRIS, NL , RONCHESE, F , (1999) THE ROLE OF B7 COSTIMULATION IN T-CELL IMMUNITY.IMMUNOLOGY AND CELL BIOLOGY. VOL. 77. ISSUE 4. P. 304-311 82 86% 101

Classes with closest relation at Level 1


Rank Class id link
1 24008 ICOS//B7RP 1//INDUCIBLE COSTIMULATOR
2 8234 CTLA 4//CTLA 4 GENE//GRAVES DISEASE
3 8124 TUMOR VACCINE//GENE THERAPY//B71
4 5296 TRANSPLANTAT BIOL//MIXED CHIMERISM//EMORY TRANSPLANT
5 9605 CD2//T11TS//CD58
6 8384 4 1BB//OX40//CD137
7 721 PD L1//PD 1//IPILIMUMAB
8 4230 IMMUNOLOGICAL SYNAPSE//LYMPHOCYTE INTERACT//PROGRAM MOL PATHOGENESIS
9 19695 TUNNELING NANOTUBES//MEMBRANE NANOTUBES//TROGOCYTOSIS
10 2576 CD40//CD40 LIGAND//CD40L

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