Class information for:
Level 1: RUFINAMIDE//CLOBAZAM//LENNOX GASTAUT SYNDROME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23232 353 27.7 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
143 3       EPILEPSY//EPILEPSIA//EPILEPSY & BEHAVIOR 64226
230 2             ANTIEPILEPTIC DRUGS//LEVETIRACETAM//EPILEPSY 20331
23232 1                   RUFINAMIDE//CLOBAZAM//LENNOX GASTAUT SYNDROME 353

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RUFINAMIDE authKW 4072509 18% 74% 64
2 CLOBAZAM authKW 2661373 18% 49% 63
3 LENNOX GASTAUT SYNDROME authKW 2068309 22% 30% 79
4 DROP SEIZURES authKW 617864 3% 71% 10
5 N DESMETHYLCLOBAZAM authKW 615122 2% 89% 8
6 TOTAL SEIZURES authKW 259505 1% 100% 3
7 IHARAS GENETICALLY EPILEPTIC RAT IGER authKW 173004 1% 100% 2
8 PERSONALITY DISORDERS DRUG THERAPY authKW 173004 1% 100% 2
9 CHILD FAMILIY HLTH SERV address 115334 1% 67% 2
10 IHARA EPILEPTIC RAT authKW 115334 1% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Clinical Neurology 6858 60% 0% 212
2 Pharmacology & Pharmacy 704 27% 0% 97
3 Pediatrics 328 11% 0% 40
4 Psychiatry 190 9% 0% 33
5 Neurosciences 83 11% 0% 40
6 Medical Laboratory Technology 52 2% 0% 8
7 Behavioral Sciences 49 3% 0% 11
8 Toxicology 33 4% 0% 13
9 Medicine, General & Internal 15 5% 0% 17
10 Crystallography 12 2% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHILD FAMILIY HLTH SERV 115334 1% 67% 2
2 KLIN NEUROPADIATRIE NEUROL REHABIL 111213 1% 43% 3
3 ASSOCIATE SCIENTIST 86502 0% 100% 1
4 BIOL MOL PL MED 86502 0% 100% 1
5 CEAINSERM U1129NEUROPEDIAT 86502 0% 100% 1
6 CEAINSERM U1129NEUROPEDIAT REFERENCE 86502 0% 100% 1
7 CHILD ADOLESCENT NEUROPSYCHIAT MED 86502 0% 100% 1
8 CHILDRENS HOSPASAN MED PEDIAT NEUROL 86502 0% 100% 1
9 CLIN NEUROPAEDIAT NEUROREHABILITAT 86502 0% 100% 1
10 CLIN NEUROPEDIATR NEUROL REHABIL 86502 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPILEPSIA 22399 14% 1% 48
2 SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 6969 4% 1% 14
3 EPILEPSY RESEARCH 6443 5% 0% 17
4 CLINICAL ELECTROENCEPHALOGRAPHY 5585 2% 1% 7
5 EPILEPTIC DISORDERS 4195 2% 1% 7
6 EPILEPSY CURRENTS 2832 1% 2% 2
7 EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY 2814 2% 1% 6
8 EPILEPSY & BEHAVIOR 2553 3% 0% 11
9 THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS 2258 1% 1% 2
10 THERAPEUTIC DRUG MONITORING 1470 2% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RUFINAMIDE 4072509 18% 74% 64 Search RUFINAMIDE Search RUFINAMIDE
2 CLOBAZAM 2661373 18% 49% 63 Search CLOBAZAM Search CLOBAZAM
3 LENNOX GASTAUT SYNDROME 2068309 22% 30% 79 Search LENNOX+GASTAUT+SYNDROME Search LENNOX+GASTAUT+SYNDROME
4 DROP SEIZURES 617864 3% 71% 10 Search DROP+SEIZURES Search DROP+SEIZURES
5 N DESMETHYLCLOBAZAM 615122 2% 89% 8 Search N+DESMETHYLCLOBAZAM Search N+DESMETHYLCLOBAZAM
6 TOTAL SEIZURES 259505 1% 100% 3 Search TOTAL+SEIZURES Search TOTAL+SEIZURES
7 IHARAS GENETICALLY EPILEPTIC RAT IGER 173004 1% 100% 2 Search IHARAS+GENETICALLY+EPILEPTIC+RAT+IGER Search IHARAS+GENETICALLY+EPILEPTIC+RAT+IGER
8 PERSONALITY DISORDERS DRUG THERAPY 173004 1% 100% 2 Search PERSONALITY+DISORDERS+DRUG+THERAPY Search PERSONALITY+DISORDERS+DRUG+THERAPY
9 IHARA EPILEPTIC RAT 115334 1% 67% 2 Search IHARA+EPILEPTIC+RAT Search IHARA+EPILEPTIC+RAT
10 PAROXYSMAL FAST ACTIVITY 115334 1% 67% 2 Search PAROXYSMAL+FAST+ACTIVITY Search PAROXYSMAL+FAST+ACTIVITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SEIF-EDDEINE, H , NG, YT , (2012) CLOBAZAM FOR PATIENTS WITH LENNOX-GASTAUT SYNDROME AND EPILEPSY.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 12. ISSUE 4. P. 385-393 47 66% 5
2 NG, YT , COLLINS, SD , (2007) CLOBAZAM.NEUROTHERAPEUTICS. VOL. 4. ISSUE 1. P. 138-144 37 86% 41
3 GAUTHIER, AC , MATTSON, RH , (2015) CLOBAZAM: A SAFE, EFFICACIOUS, AND NEWLY REDISCOVERED THERAPEUTIC FOR EPILEPSY.CNS NEUROSCIENCE & THERAPEUTICS. VOL. 21. ISSUE 7. P. 543 -548 34 74% 4
4 WHELESS, JW , PHELPS, SJ , (2013) CLOBAZAM: A NEWLY APPROVED BUT WELL-ESTABLISHED DRUG FOR THE TREATMENT OF INTRACTABLE EPILEPSY SYNDROMES.JOURNAL OF CHILD NEUROLOGY. VOL. 28. ISSUE 2. P. 219-229 33 79% 8
5 KLEHM, J , THOME-SOUZA, S , FERNANDEZ, IS , BERGIN, AM , BOLTON, J , HARINI, C , KADISH, NE , LIBENSON, M , PETERS, J , PODURI, A , ET AL (2014) CLOBAZAM: EFFECT ON FREQUENCY OF SEIZURES AND SAFETY PROFILE IN DIFFERENT SUBGROUPS OF CHILDREN WITH EPILEPSY.PEDIATRIC NEUROLOGY. VOL. 51. ISSUE 1. P. 60 -66 29 83% 3
6 COPPOLA, G , BESAG, F , CUSMAI, R , DULAC, O , KLUGER, G , MOAVERO, R , NABBOUT, R , NIKANOROVA, M , PISANI, F , VERROTTI, A , ET AL (2014) CURRENT ROLE OF RUFINAMIDE IN THE TREATMENT OF CHILDHOOD EPILEPSY: LITERATURE REVIEW AND TREATMENT GUIDELINES.EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY. VOL. 18. ISSUE 6. P. 685 -690 25 93% 4
7 HSIEH, DT , THIELE, EA , (2013) EFFICACY AND SAFETY OF RUFINAMIDE IN PEDIATRIC EPILEPSY.THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. VOL. 6. ISSUE 3. P. 189-198 29 81% 6
8 GROSSO, S , COPPOLA, G , DONTIN, SD , GOBBI, G , PRUNA, D , ACCORSI, EP , VERROTTI, A , PARISI, P , BALESTRI, P , (2014) EFFICACY AND SAFETY OF RUFINAMIDE IN CHILDREN UNDER FOUR YEARS OF AGE WITH DRUG-RESISTANT EPILEPSIES.EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY. VOL. 18. ISSUE 5. P. 641 -645 25 89% 2
9 DE LEON, J , SPINA, E , DIAZ, FJ , (2013) CLOBAZAM THERAPEUTIC DRUG MONITORING: A COMPREHENSIVE REVIEW OF THE LITERATURE WITH PROPOSALS TO IMPROVE FUTURE STUDIES.THERAPEUTIC DRUG MONITORING. VOL. 35. ISSUE 1. P. 30-47 41 53% 10
10 FAULKNER, MA , (2015) COMPREHENSIVE OVERVIEW: EFFICACY, TOLERABILITY, AND COST-EFFECTIVENESS OF CLOBAZAM IN LENNOX-GASTAUT SYNDROME.THERAPEUTICS AND CLINICAL RISK MANAGEMENT. VOL. 11. ISSUE . P. - 27 73% 1

Classes with closest relation at Level 1


Rank Class id link
1 19178 LACOSAMIDE//ESLICARBAZEPINE ACETATE//PERAMPANEL
2 23193 CORPUS CALLOSOTOMY//CALLOSOTOMY//DROP ATTACKS
3 10778 WEST SYNDROME//INFANTILE SPASMS//HYPSARRHYTHMIA
4 3055 LAMOTRIGINE//FELBAMATE//OXCARBAZEPINE
5 3699 DRAVET SYNDROME//SCN1A//GEFS
6 14744 TOPIRAMATE//TOPIRAMATE TOPAMAX//QUDEXY XR
7 8871 BROMAZEPAM//FLUNITRAZEPAM//BENZODIAZEPINES
8 13287 ABECARNIL//PRECIPITATED ABSTINENCE//BENZODIAZEPINES
9 5865 JUVENILE MYOCLONIC EPILEPSY//IDIOPATHIC GENERALIZED EPILEPSY//REFLEX EPILEPSY
10 34927 REMACEMIDE//LOSIGAMONE//DESGLYCINYL REMACEMIDE

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