Class information for:
Level 1: SERAM//MATH CHEM//RELATIVE BINDING AFFINITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12278 918 40.7 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
329 2             TAMOXIFEN//ESTROGEN RECEPTOR//AROMATASE INHIBITORS 18133
12278 1                   SERAM//MATH CHEM//RELATIVE BINDING AFFINITY 918

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SERAM authKW 267665 1% 62% 13
2 MATH CHEM address 256612 3% 31% 25
3 RELATIVE BINDING AFFINITY authKW 144604 1% 43% 10
4 SERMS authKW 120004 3% 12% 29
5 ESTROGEN RECEPTOR authKW 105980 16% 2% 146
6 ESTROGEN RECEPTOR LIGANDS authKW 101855 1% 44% 7
7 COUNTERPROPAGATION ARTIFICIAL NEURAL NETWORK authKW 99784 0% 100% 3
8 TETRAHYDROFLUORENONE authKW 99784 0% 100% 3
9 SAR AND QSAR IN ENVIRONMENTAL RESEARCH journal 74473 5% 5% 42
10 3D QSDAR authKW 66523 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 14094 37% 0% 337
2 Computer Science, Interdisciplinary Applications 1736 12% 0% 112
3 Chemistry, Organic 1470 19% 0% 176
4 Toxicology 1204 11% 0% 105
5 Mathematical & Computational Biology 998 6% 0% 58
6 Biochemistry & Molecular Biology 615 25% 0% 227
7 Endocrinology & Metabolism 583 11% 0% 99
8 Chemistry, Multidisciplinary 559 18% 0% 168
9 Environmental Sciences 360 11% 0% 103
10 Pharmacology & Pharmacy 185 11% 0% 99

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MATH CHEM 256612 3% 31% 25
2 CHEM SCREENING SCI MED CHEM 66523 0% 100% 2
3 CHEM SCREENING SCI STRUCT BIOL 66523 0% 100% 2
4 ENVIRONM BIOCHEM CHEM 66523 0% 100% 2
5 TOXICOINFORMAT 64495 1% 24% 8
6 ROGER ADAMS 461 53213 0% 40% 4
7 KARO BIO AB 50921 1% 22% 7
8 ATHEROSCLEROSIS ENDOCRINOL 47251 1% 16% 9
9 TSCA INTERAGCY TESTING COMM 35473 0% 27% 4
10 QSAR UNIT ENVIRONM CHEM ECOTOXICOL 34883 1% 13% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SAR AND QSAR IN ENVIRONMENTAL RESEARCH 74473 5% 5% 42
2 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 10408 10% 0% 89
3 JOURNAL OF MEDICINAL CHEMISTRY 7109 7% 0% 68
4 STEROIDS 6413 3% 1% 29
5 JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES 5171 2% 1% 21
6 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2855 3% 0% 28
7 BIOORGANIC & MEDICINAL CHEMISTRY 2418 3% 0% 31
8 QSAR & COMBINATORIAL SCIENCE 1919 1% 1% 6
9 JOURNAL OF MOLECULAR GRAPHICS & MODELLING 1765 1% 1% 10
10 CHEMMEDCHEM 1435 1% 0% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SERAM 267665 1% 62% 13 Search SERAM Search SERAM
2 RELATIVE BINDING AFFINITY 144604 1% 43% 10 Search RELATIVE+BINDING+AFFINITY Search RELATIVE+BINDING+AFFINITY
3 SERMS 120004 3% 12% 29 Search SERMS Search SERMS
4 ESTROGEN RECEPTOR 105980 16% 2% 146 Search ESTROGEN+RECEPTOR Search ESTROGEN+RECEPTOR
5 ESTROGEN RECEPTOR LIGANDS 101855 1% 44% 7 Search ESTROGEN+RECEPTOR+LIGANDS Search ESTROGEN+RECEPTOR+LIGANDS
6 COUNTERPROPAGATION ARTIFICIAL NEURAL NETWORK 99784 0% 100% 3 Search COUNTERPROPAGATION+ARTIFICIAL+NEURAL+NETWORK Search COUNTERPROPAGATION+ARTIFICIAL+NEURAL+NETWORK
7 TETRAHYDROFLUORENONE 99784 0% 100% 3 Search TETRAHYDROFLUORENONE Search TETRAHYDROFLUORENONE
8 3D QSDAR 66523 0% 100% 2 Search 3D+QSDAR Search 3D+QSDAR
9 ACTIVE ANALOGUES 66523 0% 100% 2 Search ACTIVE+ANALOGUES Search ACTIVE+ANALOGUES
10 COSASA 66523 0% 100% 2 Search COSASA Search COSASA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NG, HW , PERKINS, R , TONG, WS , HONG, HX , (2014) VERSATILITY OR PROMISCUITY: THE ESTROGEN RECEPTORS, CONTROL OF LIGAND SELECTIVITY AND AN UPDATE ON SUBTYPE SELECTIVE LIGANDS.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. VOL. 11. ISSUE 9. P. 8709 -8742 71 59% 9
2 MINUTOLO, F , MACCHIA, M , KATZENELLENBOGEN, BS , KATZENELLENBOGEN, JA , (2011) ESTROGEN RECEPTOR BETA LIGANDS: RECENT ADVANCES AND BIOMEDICAL APPLICATIONS.MEDICINAL RESEARCH REVIEWS. VOL. 31. ISSUE 3. P. 364 -442 87 42% 59
3 SPYRAKIS, F , COZZINI, P , (2009) HOW COMPUTATIONAL METHODS TRY TO DISCLOSE THE ESTROGEN RECEPTOR SECRECY - MODELING THE FLEXIBILITY.CURRENT MEDICINAL CHEMISTRY. VOL. 16. ISSUE 23. P. 2987 -3027 124 28% 3
4 VEENEMAN, GH , (2005) NON-STEROIDAL SUBTYPE SELECTIVE ESTROGENS.CURRENT MEDICINAL CHEMISTRY. VOL. 12. ISSUE 9. P. 1077-1136 51 65% 43
5 TAHA, MO , TARAIRAH, M , ZALLOUM, H , ABU-SHEIKHA, G , (2010) PHARMACOPHORE AND QSAR MODELING OF ESTROGEN RECEPTOR BETA LIGANDS AND SUBSEQUENT VALIDATION AND IN SILICO SEARCH FOR NEW HITS.JOURNAL OF MOLECULAR GRAPHICS & MODELLING. VOL. 28. ISSUE 5. P. 383-400 46 61% 14
6 FANG, J , SHEN, J , CHENG, FX , XU, ZJ , LIU, GX , TANG, Y , (2011) COMPUTATIONAL INSIGHTS INTO LIGAND SELECTIVITY OF ESTROGEN RECEPTORS FROM PHARMACOPHORE MODELING.MOLECULAR INFORMATICS. VOL. 30. ISSUE 6-7. P. 539-549 37 70% 3
7 DEVILLERS, J , MARCHAND-GENESTE, N , CARPY, A , PORCHER, JM , (2006) SAR AND QSAR MODELING OF ENDOCRINE DISRUPTORS.SAR AND QSAR IN ENVIRONMENTAL RESEARCH. VOL. 17. ISSUE 4. P. 393 -412 52 45% 25
8 PULKKINEN, JT , HONKAKOSKI, P , PERAKYLA, M , BERCZI, I , LAATIKAINEN, R , (2008) SYNTHESIS AND EVALUATION OF ESTROGEN AGONISM OF DIARYL 4,5-DIHYDROISOXAZOLES, 3-HYDROXYKETONES, 3-METHOXYKETONES, AND 1,3-DIKETONES: A COMPOUND SET FORMING A 4D MOLECULAR LIBRARY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 51. ISSUE 12. P. 3562 -3571 37 57% 19
9 BLIZZARD, TA , (2008) SELECTIVE ESTROGEN RECEPTOR MODULATOR MEDICINAL CHEMISTRY AT MERCK. A REVIEW.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 8. ISSUE 9. P. 792-812 28 76% 15
10 SCHMIEDER, PK , ANKLEY, G , MEKENYAN, O , WALKER, JD , BRADBURY, S , (2003) QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP MODELS FOR PREDICTION OF ESTROGEN RECEPTOR BINDING AFFINITY OF STRUCTURALLY DIVERSE CHEMICALS.ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. VOL. 22. ISSUE 8. P. 1844 -1854 33 70% 26

Classes with closest relation at Level 1


Rank Class id link
1 6912 ESTROGEN RECEPTOR BETA//ER BETA//RECEPTOR BIOL SECT
2 10644 ESTROGEN RECEPTOR//ESTROGEN RECEPTOR VARIANTS//TAMOXIFEN AZIRIDINE
3 20988 LEHRSTUHL PHARMAZEUT CHEM 2//GRP RECH ONCOL ENDOCRINOL MOL//PORPHYRIN PLATINUM CONJUGATES
4 16557 FLUOROESTRADIOL//F 18 FES PET//F 18FES
5 5771 ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS
6 13497 COMFA//MULTIDIMENSIONAL QSAR//3D QSAR
7 25786 CENTCHROMAN//ORMELOXIFENE//TCCU
8 10428 BAZEDOXIFENE//RALOXIFENE//TISSUE SELECTIVE ESTROGEN COMPLEX
9 9000 STEROID HORMONES SECT//AIB1//SRC 3
10 15128 HERSHBERGER ASSAY//VINCLOZOLIN//STYRENE TRIMER

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