Class information for:
Level 1: HYPUSINE//EIF5A//DEOXYHYPUSINE SYNTHASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18997 527 41.2 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
496 3       WHIPPLES DISEASE//POLYAMINES//TROPHERYMA WHIPPLEI 22789
1136 2             POLYAMINES//SPERMIDINE//PUTRESCINE 9579
18997 1                   HYPUSINE//EIF5A//DEOXYHYPUSINE SYNTHASE 527

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPUSINE authKW 4544025 17% 88% 89
2 EIF5A authKW 4474339 18% 83% 93
3 DEOXYHYPUSINE SYNTHASE authKW 1818822 7% 83% 38
4 EUKARYOTIC INITIATION FACTOR 5A authKW 780670 3% 84% 16
5 DEOXYHYPUSINE HYDROXYLASE authKW 757091 3% 93% 14
6 EIF5A2 authKW 741635 3% 80% 16
7 HYPUSINATION authKW 469318 2% 90% 9
8 DEOXYHYPUSINE authKW 412021 2% 89% 8
9 GC7 authKW 354885 1% 88% 7
10 EUKARYOTIC TRANSLATION INITIATION FACTOR 5A authKW 337105 2% 73% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2716 59% 0% 310
2 Biophysics 334 10% 0% 53
3 Cell Biology 278 13% 0% 71
4 Plant Sciences 121 8% 0% 43
5 Oncology 77 8% 0% 44
6 Biochemical Research Methods 62 5% 0% 24
7 Genetics & Heredity 55 6% 0% 30
8 Biotechnology & Applied Microbiology 30 5% 0% 25
9 Microbiology 28 5% 0% 24
10 Parasitiology 20 2% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ORAL PHARYNGEAL CANC BRANCH 213991 8% 8% 44
2 EDUC BASE BASIC MED SCI MOL MED 115881 0% 100% 2
3 TECH CHEM PHARMAZEUT CHEM 115881 0% 100% 2
4 ANTIVIRAL STRATEGIES 57941 0% 100% 1
5 CELL BIOL MED GENET MOL MED C 57941 0% 100% 1
6 CELL DEV NEUROSCI 57941 0% 100% 1
7 CHEM POB 939 57941 0% 100% 1
8 ENFERMEDADES INFECCIOSAS INMUNOL PEDIATES 57941 0% 100% 1
9 GEN SURGMINIST PUBL HLTH 57941 0% 100% 1
10 GLOBAL ENZYMOL KINET 57941 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOLOGICAL SIGNALS 25336 1% 6% 7
2 AMINO ACIDS 9335 5% 1% 24
3 JOURNAL OF BIOLOGICAL CHEMISTRY 1361 12% 0% 61
4 FEBS JOURNAL 517 1% 0% 7
5 BIOCHEMICAL JOURNAL 484 3% 0% 16
6 GENE THERAPY AND MOLECULAR BIOLOGY 415 0% 1% 1
7 PLANT MOLECULAR BIOLOGY 412 1% 0% 7
8 ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL 390 0% 1% 1
9 NATURE CHEMICAL BIOLOGY 375 1% 0% 3
10 EXPERIMENTAL AND MOLECULAR MEDICINE 365 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HYPUSINE 4544025 17% 88% 89 Search HYPUSINE Search HYPUSINE
2 EIF5A 4474339 18% 83% 93 Search EIF5A Search EIF5A
3 DEOXYHYPUSINE SYNTHASE 1818822 7% 83% 38 Search DEOXYHYPUSINE+SYNTHASE Search DEOXYHYPUSINE+SYNTHASE
4 EUKARYOTIC INITIATION FACTOR 5A 780670 3% 84% 16 Search EUKARYOTIC+INITIATION+FACTOR+5A Search EUKARYOTIC+INITIATION+FACTOR+5A
5 DEOXYHYPUSINE HYDROXYLASE 757091 3% 93% 14 Search DEOXYHYPUSINE+HYDROXYLASE Search DEOXYHYPUSINE+HYDROXYLASE
6 EIF5A2 741635 3% 80% 16 Search EIF5A2 Search EIF5A2
7 HYPUSINATION 469318 2% 90% 9 Search HYPUSINATION Search HYPUSINATION
8 DEOXYHYPUSINE 412021 2% 89% 8 Search DEOXYHYPUSINE Search DEOXYHYPUSINE
9 GC7 354885 1% 88% 7 Search GC7 Search GC7
10 EUKARYOTIC TRANSLATION INITIATION FACTOR 5A 337105 2% 73% 8 Search EUKARYOTIC+TRANSLATION+INITIATION+FACTOR+5A Search EUKARYOTIC+TRANSLATION+INITIATION+FACTOR+5A

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DEVER, TE , GUTIERREZ, E , SHIN, BS , (2014) THE HYPUSINE-CONTAINING TRANSLATION FACTOR EIF5A.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 49. ISSUE 5. P. 413 -425 88 85% 20
2 MATHEWS, MB , HERSHEY, JWB , (2015) THE TRANSLATION FACTOR EIF5A AND HUMAN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. VOL. 1849. ISSUE 7. P. 836 -844 74 87% 11
3 LASSAK, J , WILSON, DN , JUNG, K , (2016) STALL NO MORE AT POLYPROLINE STRETCHES WITH THE TRANSLATION ELONGATION FACTORS EF-P AND IF-5A.MOLECULAR MICROBIOLOGY. VOL. 99. ISSUE 2. P. 219 -235 73 63% 7
4 ROSSI, D , KUROSHU, R , ZANELLI, CF , VALENTINI, SR , (2014) EIF5A AND EF-P: TWO UNIQUE TRANSLATION FACTORS ARE NOW TRAVELING THE SAME ROAD.WILEY INTERDISCIPLINARY REVIEWS-RNA. VOL. 5. ISSUE 2. P. 209-222 72 82% 17
5 CARAGLIA, M , PARK, MH , WOLFF, EC , MARRA, M , ABBRUZZESE, A , (2013) EIF5A ISOFORMS AND CANCER: TWO BROTHERS FOR TWO FUNCTIONS?.AMINO ACIDS. VOL. 44. ISSUE 1. P. 103-109 56 90% 28
6 PARK, MH , NISHIMURA, K , ZANELLI, CF , VALENTINI, SR , (2010) FUNCTIONAL SIGNIFICANCE OF EIF5A AND ITS HYPUSINE MODIFICATION IN EUKARYOTES.AMINO ACIDS. VOL. 38. ISSUE 2. P. 491 -500 48 87% 116
7 PARK, MH , (2006) THE POST-TRANSLATIONAL SYNTHESIS OF A POLYAMINE-DERIVED AMINO ACID, HYPUSINE, IN THE EUKARYOTIC TRANSLATION INITIATION FACTOR 5A (EIF5A).JOURNAL OF BIOCHEMISTRY. VOL. 139. ISSUE 2. P. 161-169 47 87% 148
8 CANO, VSP , JEON, GA , JOHANSSON, HE , HENDERSON, CA , PARK, JH , VALENTINI, SR , HERSHEY, JWB , PARK, MH , (2008) MUTATIONAL ANALYSES OF HUMAN EIF5A-1-IDENTIFICATION OF AMINO ACID RESIDUES CRITICAL FOR EIF5A ACTIVITY AND HYPUSINE MODIFICATION.FEBS JOURNAL. VOL. 275. ISSUE 1. P. 44-58 50 91% 16
9 WOLFF, EC , KANG, KR , KIM, YS , PARK, MH , (2007) POSTTRANSLATIONAL SYNTHESIS OF HYPUSINE: EVOLUTIONARY PROGRESSION AND SPECIFICITY OF THE HYPUSINE MODIFICATION.AMINO ACIDS. VOL. 33. ISSUE 2. P. 341-350 44 94% 64
10 NAKANISHI, S , CLEVELAND, JL , (2016) TARGETING THE POLYAMINE-HYPUSINE CIRCUIT FOR THE PREVENTION AND TREATMENT OF CANCER.AMINO ACIDS. VOL. 48. ISSUE 10. P. 2353 -2362 46 73% 0

Classes with closest relation at Level 1


Rank Class id link
1 16563 AMINE PHARMA//RIBOSOME MODULATION FACTOR//CALDOPENTAMINE
2 14339 SPERMIDINE SYNTHASE//S ADENOSYLMETHIONINE DECARBOXYLASE//AMINOPROPYLTRANSFERASE
3 12194 REV//RRE//REV PROTEIN
4 33291 AAPTAMINE//AAPTOS AAPTOS//4 BROMOMETHYLQUINOLINE 2 ONE
5 100 POLYAMINES//ORNITHINE DECARBOXYLASE//ANTIZYME
6 36415 VACCINE NANOTECHNOL//NANOPARTICULATE VACCINE//WHOLE CELL LYSATE
7 19273 MIMOSINE//LEUCAENA LEUCOCEPHALA//LEUCAENA
8 27205 CD83//INTEGRAT INFECT IMMUN//SOLUBLE CD83
9 18779 TMRNA//TRANS TRANSLATION//SMPB
10 6259 GENE REGULAT DEV//EIF3//EIF2

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