Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
18669 | 541 | 45.2 | 83% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
285 | 3 | ERDOSTEINE//PEROXIREDOXIN//GLUTATHIONE | 42405 |
870 | 2 | PEROXIREDOXIN//THIOREDOXIN//GLUTATHIONE | 11539 |
18669 | 1 | XCT//SYSTEM XC//CYSTINE GLUTAMATE ANTIPORTER | 541 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | XCT | authKW | 1416761 | 9% | 53% | 47 |
2 | SYSTEM XC | authKW | 1362625 | 7% | 62% | 39 |
3 | CYSTINE GLUTAMATE ANTIPORTER | authKW | 397429 | 2% | 54% | 13 |
4 | FOOD PL LIFE SCI | address | 285726 | 2% | 56% | 9 |
5 | SLC7A11 | authKW | 251415 | 1% | 64% | 7 |
6 | OXIDATIVE GLUTAMATE TOXICITY | authKW | 230463 | 1% | 58% | 7 |
7 | CYSTINE GLUTAMATE EXCHANGE | authKW | 203184 | 1% | 60% | 6 |
8 | GLUTAMATE CYSTINE TRANSPORTER | authKW | 169324 | 1% | 100% | 3 |
9 | XC CYSTINE TRANSPORTER | authKW | 169324 | 1% | 100% | 3 |
10 | XCT SLC7A11 | authKW | 169324 | 1% | 100% | 3 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Neurosciences | 1525 | 32% | 0% | 173 |
2 | Biochemistry & Molecular Biology | 525 | 29% | 0% | 155 |
3 | Cell Biology | 412 | 16% | 0% | 85 |
4 | Oncology | 363 | 15% | 0% | 82 |
5 | Pharmacology & Pharmacy | 129 | 11% | 0% | 62 |
6 | Physiology | 80 | 5% | 0% | 28 |
7 | Clinical Neurology | 40 | 5% | 0% | 29 |
8 | Biophysics | 27 | 4% | 0% | 20 |
9 | CYTOLOGY & HISTOLOGY | 26 | 0% | 0% | 2 |
10 | Chemistry, Medicinal | 20 | 3% | 0% | 14 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | FOOD PL LIFE SCI | 285726 | 2% | 56% | 9 |
2 | PHARMACEUT BIOTECHNOL MOL BIOL | 76812 | 1% | 19% | 7 |
3 | GLIAL BIOL MED | 75937 | 2% | 11% | 12 |
4 | CELLULAR BIOL ANAT OPHTHALMOL | 75254 | 0% | 67% | 2 |
5 | ARRHYTHMIASMINIST EDUC CHIHA | 56441 | 0% | 100% | 1 |
6 | BIOL BIOASSAYS SIGNAL TRANSDUCT | 56441 | 0% | 100% | 1 |
7 | CCM2 | 56441 | 0% | 100% | 1 |
8 | CEAUMR E01SERV NEUROVIROLSNVCRSSAIFR13 | 56441 | 0% | 100% | 1 |
9 | CIRC 425 | 56441 | 0% | 100% | 1 |
10 | CNRSIFRMP 23 HOSP UNIV RECH BIOMED | 56441 | 0% | 100% | 1 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | ENDOTHELIUM-NEW YORK | 4340 | 0% | 8% | 1 |
2 | ASN NEURO | 2262 | 1% | 1% | 3 |
3 | NEUROCHEMISTRY INTERNATIONAL | 1773 | 2% | 0% | 13 |
4 | GLIA | 969 | 1% | 0% | 8 |
5 | JOURNAL OF NEUROCHEMISTRY | 951 | 4% | 0% | 19 |
6 | ANTIOXIDANTS & REDOX SIGNALING | 886 | 1% | 0% | 7 |
7 | JOURNAL OF NEURO-ONCOLOGY | 833 | 2% | 0% | 9 |
8 | NEUROSCIENCE | 556 | 3% | 0% | 15 |
9 | PHARMACOGNOSY MAGAZINE | 541 | 1% | 0% | 3 |
10 | JOURNAL OF NEUROSCIENCE | 514 | 3% | 0% | 18 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | XCT | 1416761 | 9% | 53% | 47 | Search XCT | Search XCT |
2 | SYSTEM XC | 1362625 | 7% | 62% | 39 | Search SYSTEM+XC | Search SYSTEM+XC |
3 | CYSTINE GLUTAMATE ANTIPORTER | 397429 | 2% | 54% | 13 | Search CYSTINE+GLUTAMATE+ANTIPORTER | Search CYSTINE+GLUTAMATE+ANTIPORTER |
4 | SLC7A11 | 251415 | 1% | 64% | 7 | Search SLC7A11 | Search SLC7A11 |
5 | OXIDATIVE GLUTAMATE TOXICITY | 230463 | 1% | 58% | 7 | Search OXIDATIVE+GLUTAMATE+TOXICITY | Search OXIDATIVE+GLUTAMATE+TOXICITY |
6 | CYSTINE GLUTAMATE EXCHANGE | 203184 | 1% | 60% | 6 | Search CYSTINE+GLUTAMATE+EXCHANGE | Search CYSTINE+GLUTAMATE+EXCHANGE |
7 | GLUTAMATE CYSTINE TRANSPORTER | 169324 | 1% | 100% | 3 | Search GLUTAMATE+CYSTINE+TRANSPORTER | Search GLUTAMATE+CYSTINE+TRANSPORTER |
8 | XC CYSTINE TRANSPORTER | 169324 | 1% | 100% | 3 | Search XC+CYSTINE+TRANSPORTER | Search XC+CYSTINE+TRANSPORTER |
9 | XCT SLC7A11 | 169324 | 1% | 100% | 3 | Search XCT+SLC7A11 | Search XCT+SLC7A11 |
10 | CYSTINE GLUTAMATE EXCHANGER | 156293 | 1% | 46% | 6 | Search CYSTINE+GLUTAMATE+EXCHANGER | Search CYSTINE+GLUTAMATE+EXCHANGER |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | LEWERENZ, J , HEWETT, SJ , HUANG, Y , LAMBROS, M , GOUT, PW , KALIVAS, PW , MASSIE, A , SMOLDERS, I , METHNER, A , PERGANDE, M , ET AL (2013) THE CYSTINE/GLUTAMATE ANTIPORTER SYSTEM X(C)(-) IN HEALTH AND DISEASE: FROM MOLECULAR MECHANISMS TO NOVEL THERAPEUTIC OPPORTUNITIES.ANTIOXIDANTS & REDOX SIGNALING. VOL. 18. ISSUE 5. P. 522 -555 | 107 | 37% | 71 |
2 | CONRAD, M , SATO, H , (2012) THE OXIDATIVE STRESS-INDUCIBLE CYSTINE/GLUTAMATE ANTIPORTER, SYSTEM X(C)(-): CYSTINE SUPPLIER AND BEYOND.AMINO ACIDS. VOL. 42. ISSUE 1. P. 231-246 | 63 | 57% | 76 |
3 | LO, M , WANG, YZ , GOUT, PW , (2008) THE X(C)(-) CYSTINE/GLUTAMATE ANTIPORTER: A POTENTIAL TARGET FOR THERAPY OF CANCER AND OTHER DISEASES.JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 215. ISSUE 3. P. 593 -602 | 71 | 52% | 135 |
4 | JACKMAN, NA , ULIASZ, TF , HEWETT, JA , HEWETT, SJ , (2010) REGULATION OF SYSTEM X(C)(-) ACTIVITY AND EXPRESSION IN ASTROCYTES BY INTERLEUKIN-1 BETA: IMPLICATIONS FOR HYPOXIC NEURONAL INJURY.GLIA. VOL. 58. ISSUE 15. P. 1806-1815 | 46 | 64% | 28 |
5 | MASSIE, A , BOILLEE, S , HEWETT, S , KNACKSTEDT, L , LEWERENZ, J , (2015) MAIN PATH AND BYWAYS: NON-VESICULAR GLUTAMATE RELEASE BY SYSTEM X(C)(-) AS AN IMPORTANT MODIFIER OF GLUTAMATERGIC NEUROTRANSMISSION.JOURNAL OF NEUROCHEMISTRY. VOL. 135. ISSUE 6. P. 1062 -1079 | 59 | 40% | 7 |
6 | SHI, JX , HE, Y , HEWETT, SJ , HEWETT, JA , (2016) INTERLEUKIN 1 BETA REGULATION OF THE SYSTEM X(C)(-), SUBSTRATE-SPECIFIC SUBUNIT, XCT, IN PRIMARY MOUSE ASTROCYTES INVOLVES THE RNA-BINDING PROTEIN HUR.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 291. ISSUE 4. P. 1643 -1651 | 40 | 61% | 0 |
7 | BRIDGES, RJ , NATALE, NR , PATEL, SA , (2012) SYSTEM XC- CYSTINE/GLUTAMATE ANTIPORTER: AN UPDATE ON MOLECULAR PHARMACOLOGY AND ROLES WITHIN THE CNS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 165. ISSUE 1. P. 20 -34 | 51 | 40% | 56 |
8 | THOMAS, AG , SATTLER, R , TENDYKE, K , LOIACONO, KA , HANSEN, H , SAHNI, V , HASHIZUME, Y , ROJAS, C , SLUSHER, BS , (2015) HIGH-THROUGHPUT ASSAY DEVELOPMENT FOR CYSTINE-GLUTAMATE ANTIPORTER (X(C)(-)) HIGHLIGHTS FASTER CYSTINE UPTAKE THAN GLUTAMATE RELEASE IN GLIOMA CELLS.PLOS ONE. VOL. 10. ISSUE 8. P. - | 32 | 68% | 1 |
9 | LEWERENZ, J , MAHER, P , METHNER, A , (2012) REGULATION OF XCT EXPRESSION AND SYSTEM X(C)(-) FUNCTION IN NEURONAL CELLS.AMINO ACIDS. VOL. 42. ISSUE 1. P. 171-179 | 38 | 52% | 28 |
10 | SORIA, FN , ZABALA, A , PAMPLIEGA, O , PALOMINO, A , MIGUELEZ, C , UGEDO, L , SATO, H , MATUTE, C , DOMERCQ, M , (2016) CYSTINE/GLUTAMATE ANTIPORTER BLOCKAGE INDUCES MYELIN DEGENERATION.GLIA. VOL. 64. ISSUE 8. P. 1381 -1395 | 34 | 59% | 0 |
Classes with closest relation at Level 1 |