Class information for:
Level 1: CELLULAR INJURY//TOLERANCE BREAKDOWN//HUNAN MED EPIGEN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16241 665 54.1 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
396 3       SYSTEMIC LUPUS ERYTHEMATOSUS//ANTIPHOSPHOLIPID SYNDROME//LUPUS 30351
302 2             SYSTEMIC LUPUS ERYTHEMATOSUS//LUPUS//LUPUS NEPHRITIS 18563
16241 1                   CELLULAR INJURY//TOLERANCE BREAKDOWN//HUNAN MED EPIGEN 665

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR INJURY address 874254 7% 40% 48
2 TOLERANCE BREAKDOWN authKW 270089 2% 59% 10
3 HUNAN MED EPIGEN address 215213 2% 31% 15
4 SECT RHEUMATOL CLIN IMMUNOL address 183650 2% 33% 12
5 TCR ZETA CHAIN authKW 143036 1% 35% 9
6 GEOEPIDEMIOLOGY authKW 128237 1% 31% 9
7 RHEUMATOLBETH ISRAEL DEACONESS MED address 122441 1% 67% 4
8 HUNAN MED EPIGENOM address 110192 1% 40% 6
9 CANC 5310 address 91833 0% 100% 2
10 IMMUNOL PATHOL IMMUNOTHER Y EA2216 address 91833 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Rheumatology 11295 24% 0% 158
2 Immunology 7402 50% 0% 335
3 Allergy 884 6% 0% 37
4 Medicine, Research & Experimental 136 6% 0% 43
5 Cell Biology 105 8% 0% 56
6 Genetics & Heredity 56 5% 0% 35
7 Dermatology 23 2% 0% 13
8 Biochemistry & Molecular Biology 15 9% 0% 60
9 Pathology 9 2% 0% 12
10 Medicine, General & Internal 3 3% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR INJURY 874254 7% 40% 48
2 HUNAN MED EPIGEN 215213 2% 31% 15
3 SECT RHEUMATOL CLIN IMMUNOL 183650 2% 33% 12
4 RHEUMATOLBETH ISRAEL DEACONESS MED 122441 1% 67% 4
5 HUNAN MED EPIGENOM 110192 1% 40% 6
6 CANC 5310 91833 0% 100% 2
7 IMMUNOL PATHOL IMMUNOTHER Y EA2216 91833 0% 100% 2
8 EXPT HTS 82647 0% 60% 3
9 AUTOIMMUN METAB UNIT 81987 1% 36% 5
10 CHROMATIN DIS GRP 75337 1% 21% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY 59379 5% 4% 36
2 AUTOIMMUNITY REVIEWS 27908 5% 2% 32
3 JOURNAL OF AUTOIMMUNITY 26650 6% 2% 38
4 CLINICAL IMMUNOLOGY 11591 4% 1% 26
5 AUTOIMMUNITY 8769 3% 1% 20
6 ARTHRITIS AND RHEUMATISM 8243 6% 0% 43
7 LUPUS 6458 3% 1% 23
8 JOURNAL OF IMMUNOLOGY 3917 10% 0% 68
9 INTERNATIONAL REVIEWS OF IMMUNOLOGY 3298 1% 1% 5
10 NATURE REVIEWS RHEUMATOLOGY 3185 1% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TOLERANCE BREAKDOWN 270089 2% 59% 10 Search TOLERANCE+BREAKDOWN Search TOLERANCE+BREAKDOWN
2 TCR ZETA CHAIN 143036 1% 35% 9 Search TCR+ZETA+CHAIN Search TCR+ZETA+CHAIN
3 GEOEPIDEMIOLOGY 128237 1% 31% 9 Search GEOEPIDEMIOLOGY Search GEOEPIDEMIOLOGY
4 LUPUS 62024 7% 3% 45 Search LUPUS Search LUPUS
5 SYSTEMIC LUPUS ERYTHEMATOSUS 61377 17% 1% 113 Search SYSTEMIC+LUPUS+ERYTHEMATOSUS Search SYSTEMIC+LUPUS+ERYTHEMATOSUS
6 LUPUS T CELLS 61221 0% 67% 2 Search LUPUS+T+CELLS Search LUPUS+T+CELLS
7 HUMAN AUTOIMMUNITY 59032 0% 43% 3 Search HUMAN+AUTOIMMUNITY Search HUMAN+AUTOIMMUNITY
8 1 RETROTRANSPOSON 45917 0% 100% 1 Search 1+RETROTRANSPOSON Search 1+RETROTRANSPOSON
9 ACCEPTANCE OF AUTOIMMUNITY 45917 0% 100% 1 Search ACCEPTANCE+OF+AUTOIMMUNITY Search ACCEPTANCE+OF+AUTOIMMUNITY
10 ACUTE BRONCHOPULMONARY ASPERGILLOSIS 45917 0% 100% 1 Search ACUTE+BRONCHOPULMONARY+ASPERGILLOSIS Search ACUTE+BRONCHOPULMONARY+ASPERGILLOSIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LONG, H , YIN, H , WANG, L , GERSHWIN, ME , LU, QJ , (2016) THE CRITICAL ROLE OF EPIGENETICS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND AUTOIMMUNITY.JOURNAL OF AUTOIMMUNITY. VOL. 74. ISSUE . P. 118 -138 85 39% 2
2 MOULTON, VR , TSOKOS, GC , (2015) T CELL SIGNALING ABNORMALITIES CONTRIBUTE TO ABERRANT IMMUNE CELL FUNCTION AND AUTOIMMUNITY.JOURNAL OF CLINICAL INVESTIGATION. VOL. 125. ISSUE 6. P. 2220 -2227 49 49% 12
3 MIAO, CG , YANG, JT , YANG, YY , DU, CL , HUANG, C , HUANG, Y , ZHANG, L , LV, XW , JIN, Y , LI, J , (2014) CRITICAL ROLE OF DNA METHYLATION IN THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS: NEW ADVANCES AND FUTURE CHALLENGES.LUPUS. VOL. 23. ISSUE 8. P. 730 -742 53 52% 4
4 MOULTON, VR , TSOKOS, GC , (2011) ABNORMALITIES OF T CELL SIGNALING IN SYSTEMIC LUPUS ERYTHEMATOSUS.ARTHRITIS RESEARCH & THERAPY. VOL. 13. ISSUE 2. P. - 39 60% 50
5 SUNAHORI, K , NAGPAL, K , HEDRICH, CM , MIZUI, M , FITZGERALD, LM , TSOKOS, GC , (2013) THE CATALYTIC SUBUNIT OF PROTEIN PHOSPHATASE 2A (PP2AC) PROMOTES DNA HYPOMETHYLATION BY SUPPRESSING THE PHOSPHORYLATED MITOGEN-ACTIVATED PROTEIN KINASE/EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) KINASE (MEK)/PHOSPHORYLATED ERK/DNMT1 PROTEIN PATHWAY IN T-CELLS FROM CONTROLS AND SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 288. ISSUE 30. P. - 27 82% 16
6 STRICKLAND, FM , LI, YP , JOHNSON, K , SUN, ZC , RICHARDSON, BC , (2015) CD4(+) T CELLS EPIGENETICALLY MODIFIED BY OXIDATIVE STRESS CAUSE LUPUS-LIKE AUTOIMMUNITY IN MICE.JOURNAL OF AUTOIMMUNITY. VOL. 62. ISSUE . P. 75 -80 26 72% 12
7 SUN, B , HU, L , LUO, ZY , CHEN, XP , ZHOU, HH , ZHANG, W , (2016) DNA METHYLATION PERSPECTIVES IN THE PATHOGENESIS OF AUTOIMMUNE DISEASES.CLINICAL IMMUNOLOGY. VOL. 164. ISSUE . P. 21 -27 38 50% 2
8 JEFFRIES, MA , SAWALHA, AH , (2015) AUTOIMMUNE DISEASE IN THE EPIGENETIC ERA: HOW HAS EPIGENETICS CHANGED OUR UNDERSTANDING OF DISEASE AND HOW CAN WE EXPECT THE FIELD TO EVOLVE?.EXPERT REVIEW OF CLINICAL IMMUNOLOGY. VOL. 11. ISSUE 1. P. 45 -58 48 40% 6
9 ZHANG, YQ , ZHAO, M , SAWALHA, AH , RICHARDSON, B , LU, QJ , (2013) IMPAIRED DNA METHYLATION AND ITS MECHANISMS IN CD4(+)T CELLS OF SYSTEMIC LUPUS ERYTHEMATOSUS.JOURNAL OF AUTOIMMUNITY. VOL. 41. ISSUE . P. 92 -99 40 42% 53
10 ALTOROK, N , SAWALHA, AH , (2013) EPIGENETICS IN THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS.CURRENT OPINION IN RHEUMATOLOGY. VOL. 25. ISSUE 5. P. 569 -576 32 55% 9

Classes with closest relation at Level 1


Rank Class id link
1 10461 IRF5//GENOM INVEST ONCOL GENYO//INTERFERON REGULATORY FACTOR 5
2 17144 SYSTEMIC LUPUS ERYTHEMATOSUS//HLA DP T CELLS//IL 10 592A C
3 17566 TRAUMA EMERGENCY SURG SURG CRIT CAREMASSAC//HISTONE DEACETYLASE//SURG TRAUMA EMERGENCY SURG SURG CRIT C
4 25218 ORAL BIOL ORAL MED//CD3 ZETA//ZETA CHAIN
5 16097 CD3 GAMMA//CD3 EPSILON//CORE PEPTIDE
6 5207 MIR 155//MICRORNA//MICRORNA 155
7 23444 MOL IMMUNOGENET GRP//CYTOGENET MUTAGENESIS//RUDBECK S
8 12095 FIBROBLAST LIKE SYNOVIOCYTES//SYNOVIAL FIBROBLASTS//EXPT RHEUMATOL
9 22078 ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1
10 22811 CD70//CD27//SIVA 1

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