Class information for:
Level 1: BCL10//PKC THETA//CARMA3

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15482 710 45.2 95%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
328 3       PHOSPHOLIPASE D//STIM1//REGUCALCIN 38118
1486 2             PROTEIN KINASE C//BRYOSTATIN//BRYOSTATIN 1 7631
15482 1                   BCL10//PKC THETA//CARMA3 710

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BCL10 authKW 1224045 7% 55% 52
2 PKC THETA authKW 1057116 7% 47% 52
3 CARMA3 authKW 526823 2% 88% 14
4 CARMA1 authKW 524259 2% 76% 16
5 SOTRASTAURIN authKW 517856 2% 71% 17
6 CARD11 authKW 443636 2% 74% 14
7 PROTEIN KINASE C THETA authKW 388111 3% 48% 19
8 AEB071 authKW 330812 1% 77% 10
9 UNIT CELLULAR SIGNAL INTEGRAT address 315991 2% 57% 13
10 PARACASPASE authKW 290287 1% 75% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 4343 38% 0% 269
2 Cell Biology 1303 23% 0% 164
3 Biochemistry & Molecular Biology 1000 33% 0% 237
4 Transplantation 192 4% 0% 27
5 Oncology 151 10% 0% 68
6 Chemistry, Medicinal 105 4% 0% 31
7 Hematology 75 4% 0% 28
8 Medicine, Research & Experimental 66 5% 0% 34
9 Genetics & Heredity 24 4% 0% 28
10 Allergy 20 1% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT CELLULAR SIGNAL INTEGRAT 315991 2% 57% 13
2 MOL TOXICOL PHARMACOL 121114 2% 22% 13
3 INTRACELLULAR SIGNALING GENE REGULAT 86012 0% 100% 2
4 MED BIOL HUMAN GENET 58475 3% 7% 20
5 CELLULAR SIGNAL INTEGRAT 55290 0% 43% 3
6 HUMAN GENET MOL GENET 55290 0% 43% 3
7 UNIT MOL SIGNAL TRANSDUCT INFLAMMAT 48360 2% 9% 12
8 ARAGON DEV FDN 43006 0% 100% 1
9 BIOMED MOL BIOLVIB 43006 0% 100% 1
10 CENT AFFILIATED HAIKOU HOSP 43006 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NATURE IMMUNOLOGY 6292 3% 1% 18
2 TRENDS IN IMMUNOLOGY 2685 1% 1% 9
3 FRONTIERS IN IMMUNOLOGY 2114 2% 0% 12
4 JOURNAL OF IMMUNOLOGY 2034 7% 0% 51
5 CELL COMMUNICATION AND SIGNALING 1822 1% 1% 4
6 MOLECULAR IMMUNOLOGY 1541 2% 0% 16
7 IMMUNITY 1238 1% 0% 10
8 AMERICAN JOURNAL OF TRANSPLANTATION 889 1% 0% 10
9 JOURNAL OF EXPERIMENTAL MEDICINE 874 2% 0% 16
10 EUROPEAN JOURNAL OF IMMUNOLOGY 713 2% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BCL10 1224045 7% 55% 52 Search BCL10 Search BCL10
2 PKC THETA 1057116 7% 47% 52 Search PKC+THETA Search PKC+THETA
3 CARMA3 526823 2% 88% 14 Search CARMA3 Search CARMA3
4 CARMA1 524259 2% 76% 16 Search CARMA1 Search CARMA1
5 SOTRASTAURIN 517856 2% 71% 17 Search SOTRASTAURIN Search SOTRASTAURIN
6 CARD11 443636 2% 74% 14 Search CARD11 Search CARD11
7 PROTEIN KINASE C THETA 388111 3% 48% 19 Search PROTEIN+KINASE+C+THETA Search PROTEIN+KINASE+C+THETA
8 AEB071 330812 1% 77% 10 Search AEB071 Search AEB071
9 PARACASPASE 290287 1% 75% 9 Search PARACASPASE Search PARACASPASE
10 MALT1 283042 3% 31% 21 Search MALT1 Search MALT1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MEININGER, I , KRAPPMANN, D , (2016) LYMPHOCYTE SIGNALING AND ACTIVATION BY THE CARMA1-BCL10-MALT1 SIGNALOSOME.BIOLOGICAL CHEMISTRY. VOL. 397. ISSUE 12. P. 1315 -1333 113 76% 1
2 THOME, M , CHARTON, JE , PELZER, C , HAILFINGER, S , (2010) ANTIGEN RECEPTOR SIGNALING TO NF-KAPPA B VIA CARMA1, BCL10, AND MALT1.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 2. ISSUE 9. P. - 61 72% 96
3 BLONSKA, M , LIN, X , (2011) NF-KAPPA B SIGNALING PATHWAYS REGULATED BY CARMA FAMILY OF SCAFFOLD PROTEINS.CELL RESEARCH. VOL. 21. ISSUE 1. P. 55 -70 80 51% 68
4 JAWORSKI, M , THOME, M , (2016) THE PARACASPASE MALT1: BIOLOGICAL FUNCTION AND POTENTIAL FOR THERAPEUTIC INHIBITION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 73. ISSUE 3. P. 459 -473 67 61% 1
5 JIANG, CY , LIN, X , (2012) REGULATION OF NF-KAPPA B BY THE CARD PROTEINS.IMMUNOLOGICAL REVIEWS. VOL. 246. ISSUE . P. 141-153 78 50% 33
6 BEYAERT, R , DEMEYER, A , STAAL, J , (2016) TARGETING MALT1 PROTEOLYTIC ACTIVITY IN IMMUNITY, INFLAMMATION AND DISEASE: GOOD OR BAD?.TRENDS IN MOLECULAR MEDICINE. VOL. 22. ISSUE 2. P. 135 -150 58 65% 1
7 JIMENEZ, JM , BOYALL, D , BRENCHLEY, G , COLLIER, PN , DAVIS, CJ , FRAYSSE, D , KEILY, SB , HENDERSON, J , MILLER, A , PIERARD, F , ET AL (2013) DESIGN AND OPTIMIZATION OF SELECTIVE PROTEIN KINASE C THETA (PKC THETA) INHIBITORS FOR THE TREATMENT OF AUTOIMMUNE DISEASES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 56. ISSUE 5. P. 1799 -1810 42 93% 15
8 SALVESEN, GS , HACHMANN, J , (2016) THE PARACASPASE MALT1.BIOCHIMIE. VOL. 122. ISSUE . P. 324 -338 63 58% 1
9 SCUDIERO, I , VITO, P , STILO, R , (2014) THE THREE CARMA SISTERS: SO DIFFERENT, SO SIMILAR: A PORTRAIT OF THE THREE CARMA PROTEINS AND THEIR INVOLVEMENT IN HUMAN DISORDERS.JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 229. ISSUE 8. P. 990-997 46 72% 8
10 AFONINA, IS , ELTON, L , CARPENTIER, I , BEYAERT, R , (2015) MALT1-A UNIVERSAL SOLDIER: MULTIPLE STRATEGIES TO ENSURE NF-KAPPA B ACTIVATION AND TARGET GENE EXPRESSION.FEBS JOURNAL. VOL. 282. ISSUE 17. P. 3286 -3297 45 67% 8

Classes with closest relation at Level 1


Rank Class id link
1 19765 A20//RNF11//ZINC FINGER PROTEIN A20
2 24258 TAK1//TAB1//TGF BETA ACTIVATED KINASE 1
3 32191 ENZASTAURIN//LY317615//INTRATUMORAL VESSELS
4 27455 POLIGEENAN//PL MARINE BIOTECHNOL ZHEJIANG PROV//PVAP
5 1767 PROTEIN KINASE C//PKC DELTA//CELLULAR CARCINOGENESIS TUMOR PROMOT
6 1968 MALT LYMPHOMA//GASTRIC LYMPHOMA//GASTRIC MALT LYMPHOMA
7 4230 IMMUNOLOGICAL SYNAPSE//LYMPHOCYTE INTERACT//PROGRAM MOL PATHOGENESIS
8 500 NF KAPPA B//IKK//I KAPPA B
9 13788 SLP 76//ADAP//SECT LYMPHOCYTE SIGNALING
10 22654 VAV//VAV1//VAV PROTO ONCOGENE

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