Class information for:
Level 1: CYP27B1//VITAMIN D HYDROXYLASES//ENDOCRINE BONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15377 716 34.8 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
14 4 ORTHOPEDICS//DENTISTRY, ORAL SURGERY & MEDICINE//SPORT SCIENCES 808941
32 3       OSTEOPOROSIS//VITAMIN D//OSTEOPOROSIS INTERNATIONAL 107093
179 2             VITAMIN D//25 HYDROXYVITAMIN D//VITAMIN D DEFICIENCY 21990
15377 1                   CYP27B1//VITAMIN D HYDROXYLASES//ENDOCRINE BONE 716

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYP27B1 authKW 307481 4% 23% 32
2 VITAMIN D HYDROXYLASES authKW 292418 2% 57% 12
3 ENDOCRINE BONE address 265711 1% 69% 9
4 1 ALPHA HYDROXYLASE authKW 229306 3% 24% 22
5 BONE CELL BIOL GRP address 180602 2% 35% 12
6 PSEUDOVITAMIN D DEFICIENCY RICKETS authKW 177689 1% 83% 5
7 VITAMIN D METABOLISM authKW 177116 3% 23% 18
8 VITAMIN D DEPENDENT RICKETS TYPE 1 authKW 170583 1% 100% 4
9 25 HYDROXYVITAMIN D 3 24 HYDROXYLASE authKW 160735 1% 54% 7
10 25 HYDROXYVITAMIN D 3 1 ALPHA HYDROXYLASE authKW 149253 1% 50% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 6958 38% 0% 273
2 Biochemistry & Molecular Biology 1358 38% 0% 271
3 Biophysics 695 12% 0% 87
4 Physiology 190 7% 0% 47
5 Urology & Nephrology 166 5% 0% 37
6 Medicine, Research & Experimental 107 6% 0% 41
7 Cell Biology 96 8% 0% 57
8 Nutrition & Dietetics 42 3% 0% 19
9 Pediatrics 28 3% 0% 23
10 Medical Laboratory Technology 19 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOCRINE BONE 265711 1% 69% 9
2 BONE CELL BIOL GRP 180602 2% 35% 12
3 GENET UNIT 1529 CEDAR AVE 56860 0% 67% 2
4 BORNOVA HLTH PLICAT 42646 0% 100% 1
5 CNRS UMR LC3 7177 42646 0% 100% 1
6 CORDELIERS IFR 58 42646 0% 100% 1
7 DENT MED ENDOCRINE UNIT 42646 0% 100% 1
8 DERMATOL CHILD HLTH 42646 0% 100% 1
9 DRUG DISCOVERY MOL MED S 42646 0% 100% 1
10 EMIU 0110 42646 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 10423 7% 1% 47
2 ENDOCRINOLOGY 5750 8% 0% 58
3 JOURNAL OF BONE AND MINERAL RESEARCH 3667 3% 0% 24
4 OSTEOLOGIE 3370 1% 2% 4
5 CALCIFIED TISSUE INTERNATIONAL 2531 2% 0% 17
6 BONE RESEARCH 1719 0% 2% 2
7 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1411 3% 0% 24
8 BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM 1091 1% 1% 5
9 AMERICAN JOURNAL OF PHYSIOLOGY 1043 3% 0% 25
10 BONE 759 2% 0% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYP27B1 307481 4% 23% 32 Search CYP27B1 Search CYP27B1
2 VITAMIN D HYDROXYLASES 292418 2% 57% 12 Search VITAMIN+D+HYDROXYLASES Search VITAMIN+D+HYDROXYLASES
3 1 ALPHA HYDROXYLASE 229306 3% 24% 22 Search 1+ALPHA+HYDROXYLASE Search 1+ALPHA+HYDROXYLASE
4 PSEUDOVITAMIN D DEFICIENCY RICKETS 177689 1% 83% 5 Search PSEUDOVITAMIN+D+DEFICIENCY+RICKETS Search PSEUDOVITAMIN+D+DEFICIENCY+RICKETS
5 VITAMIN D METABOLISM 177116 3% 23% 18 Search VITAMIN+D+METABOLISM Search VITAMIN+D+METABOLISM
6 VITAMIN D DEPENDENT RICKETS TYPE 1 170583 1% 100% 4 Search VITAMIN+D+DEPENDENT+RICKETS+TYPE+1 Search VITAMIN+D+DEPENDENT+RICKETS+TYPE+1
7 25 HYDROXYVITAMIN D 3 24 HYDROXYLASE 160735 1% 54% 7 Search 25+HYDROXYVITAMIN+D+3+24+HYDROXYLASE Search 25+HYDROXYVITAMIN+D+3+24+HYDROXYLASE
8 25 HYDROXYVITAMIN D 3 1 ALPHA HYDROXYLASE 149253 1% 50% 7 Search 25+HYDROXYVITAMIN+D+3+1+ALPHA+HYDROXYLASE Search 25+HYDROXYVITAMIN+D+3+1+ALPHA+HYDROXYLASE
9 25 HYDROXYVITAMIN D 1 ALPHA HYDROXYLASE 147041 1% 34% 10 Search 25+HYDROXYVITAMIN+D+1+ALPHA+HYDROXYLASE Search 25+HYDROXYVITAMIN+D+1+ALPHA+HYDROXYLASE
10 AMINO TERMINAL IMMUNOREACTIVE PARATHYROID HORMONE 127937 0% 100% 3 Search AMINO+TERMINAL+IMMUNOREACTIVE+PARATHYROID+HORMONE Search AMINO+TERMINAL+IMMUNOREACTIVE+PARATHYROID+HORMONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MILLER, WL , (2017) GENETIC DISORDERS OF VITAMIN D BIOSYNTHESIS AND DEGRADATION.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 165. ISSUE . P. 101 -108 54 57% 1
2 ZHU, JG , DELUCA, HF , (2012) VITAMIN D 25-HYDROXYLASE - FOUR DECADES OF SEARCHING, ARE WE THERE YET?.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 523. ISSUE 1. P. 30-36 45 51% 44
3 WIKVALL, K , (2001) CYTOCHROME P450 ENZYMES IN THE BIOACTIVATION OF VITAMIN D TO ITS HORMONAL FORM (REVIEW).INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. VOL. 7. ISSUE 2. P. 201-209 40 74% 39
4 JONES, G , PROSSER, DE , KAUFMANN, M , (2014) THEMATIC REVIEW SERIES: FAT-SOLUBLE VITAMINS: VITAMIN D CYTOCHROME P450-MEDIATED METABOLISM OF VITAMIN D.JOURNAL OF LIPID RESEARCH. VOL. 55. ISSUE 1. P. 13 -31 47 34% 46
5 OHYAMA, Y , YAMASAKI, T , (2004) EIGHT CYTOCHROME P450S CATALYZE VITAMIN D METABOLISM.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 9. ISSUE . P. 3007-3018 45 56% 48
6 OZCABI, B , BUCAK, FT , JAFEROVA, S , ORUC, C , ADROVIC, A , CEYLANER, S , ERCAN, O , EVLIYAOGLU, O , (2016) A CASE OF VITAMIN D-DEPENDENT RICKETS TYPE 1A WITH A NOVEL MUTATION IN THE UZBEK POPULATION.JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY. VOL. 8. ISSUE 4. P. 484 -489 20 91% 0
7 ANDERSON, PH , LAM, NN , TURNER, AG , DAVEY, RA , KOGAWA, M , ATKINS, GJ , MORRIS, HA , (2013) THE PLEIOTROPIC EFFECTS OF VITAMIN D IN BONE.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 136. ISSUE . P. 190-194 30 53% 20
8 CUI, NY , XIA, WB , SU, H , PANG, L , JIANG, Y , SUN, Y , NIE, M , XING, XP , LI, M , WANG, O , ET AL (2012) NOVEL MUTATIONS OF CYP27B1 GENE LEAD TO REDUCED ACTIVITY OF 1 ALPHA-HYDROXYLASE IN CHINESE PATIENTS.BONE. VOL. 51. ISSUE 3. P. 563-569 21 84% 6
9 ARMBRECHT, JH , OKUDA, K , WONGSURAWAT, N , NEMANI, RK , CHEN, ML , BOLTZ, MA , (1992) CHARACTERIZATION AND REGULATION OF THE VITAMIN-D HYDROXYLASES.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 43. ISSUE 8. P. 1073-1081 50 68% 4
10 OMDAHL, JL , MORRIS, HA , MAY, BK , (2002) HYDROXYLASE ENZYMES OF THE VITAMIN D PATHWAY: EXPRESSION, FUNCTION, AND REGULATION.ANNUAL REVIEW OF NUTRITION. VOL. 22. ISSUE . P. 139-166 48 38% 147

Classes with closest relation at Level 1


Rank Class id link
1 4108 24 25OH2D 3//HEREDITARY VITAMIN D RESISTANT RICKETS//1 ALPHA 25OH2D 3
2 4395 VITAMIN D ANALOGS//19 NORVITAMIN D//1 ALPHA 25 DIHYDROXYVITAMIN D 3
3 16455 DEQAS//25 HYDROXYVITAMIN D 3//3 EPI 25 HYDROXYVITAMIN D 3
4 6122 CALBINDIN D 9K//TRPV6//TRPV5
5 16549 ADRENODOXIN//CYTOCHROME P450SCC//ADRENODOXIN REDUCTASE
6 14748 ALFACALCIDOL//ELDECALCITOL//ED 71
7 11057 VITAMIN D//25 HYDROXYVITAMIN D//VITAMIN D DEFICIENCY
8 8926 ONCOGENIC OSTEOMALACIA//PHEX//PHOSPHATURIC MESENCHYMAL TUMOR
9 1610 VITAMIN D//VITAMIN D RECEPTOR//VDR
10 9039 CEREBROTENDINOUS XANTHOMATOSIS//CHOLESTEROL 7 ALPHA HYDROXYLASE//STEROL 27 HYDROXYLASE

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