Class information for:
Level 1: VITAMIN D ANALOGS//19 NORVITAMIN D//1 ALPHA 25 DIHYDROXYVITAMIN D 3

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4395 1793 33.5 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
14 4 ORTHOPEDICS//DENTISTRY, ORAL SURGERY & MEDICINE//SPORT SCIENCES 808941
32 3       OSTEOPOROSIS//VITAMIN D//OSTEOPOROSIS INTERNATIONAL 107093
179 2             VITAMIN D//25 HYDROXYVITAMIN D//VITAMIN D DEFICIENCY 21990
4395 1                   VITAMIN D ANALOGS//19 NORVITAMIN D//1 ALPHA 25 DIHYDROXYVITAMIN D 3 1793

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VITAMIN D ANALOGS authKW 280846 3% 28% 59
2 19 NORVITAMIN D authKW 187314 1% 100% 11
3 1 ALPHA 25 DIHYDROXYVITAMIN D 3 authKW 182470 3% 20% 54
4 CALCEMIC ACTIVITY authKW 170286 1% 100% 10
5 VITAMIN D RECEPTOR authKW 163417 7% 8% 118
6 BONE CALCIUM METAB address 154803 1% 91% 10
7 ED 71 authKW 151699 1% 64% 14
8 INVEST IGNACIO RIBAS address 121090 0% 89% 8
9 19 NORVITAMIN D 3 authKW 119200 0% 100% 7
10 VDR BINDING AFFINITY authKW 119200 0% 100% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 11484 36% 0% 654
2 Chemistry, Medicinal 5442 17% 0% 301
3 Endocrinology & Metabolism 2219 15% 0% 260
4 Biochemistry & Molecular Biology 2114 31% 0% 556
5 Chemistry, Multidisciplinary 743 16% 0% 282
6 Biophysics 445 7% 0% 121
7 Pharmacology & Pharmacy 213 9% 0% 161
8 Cell Biology 0 3% 0% 46
9 Nutrition & Dietetics 0 1% 0% 14
10 Biochemical Research Methods -0 1% 0% 18

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BONE CALCIUM METAB 154803 1% 91% 10
2 INVEST IGNACIO RIBAS 121090 0% 89% 8
3 TEIJIN BIOMED 107466 1% 25% 25
4 HYG SCI 100335 2% 21% 28
5 EXPT GENEESKUNDE ENDOCRINOL 93278 1% 27% 20
6 VAKGROEP ORGAN CHEM 70951 0% 83% 5
7 SYNTHET TECHNOL 53211 0% 63% 5
8 HYG CHEM NUTR 51080 0% 50% 6
9 DRUG DESIGN MED CHEM 36407 1% 16% 13
10 DIS AREA 34057 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 26236 7% 1% 118
2 STEROIDS 10960 3% 1% 53
3 TETRAHEDRON LETTERS 6102 9% 0% 164
4 JOURNAL OF ORGANIC CHEMISTRY 4979 7% 0% 124
5 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 3889 4% 0% 63
6 BIOORGANIC & MEDICINAL CHEMISTRY 3469 3% 0% 52
7 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3121 4% 0% 69
8 JOURNAL OF MEDICINAL CHEMISTRY 3059 4% 0% 63
9 CHEMICAL & PHARMACEUTICAL BULLETIN 2393 3% 0% 50
10 CURRENT TOPICS IN MEDICINAL CHEMISTRY 1896 1% 1% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 VITAMIN D ANALOGS 280846 3% 28% 59 Search VITAMIN+D+ANALOGS Search VITAMIN+D+ANALOGS
2 19 NORVITAMIN D 187314 1% 100% 11 Search 19+NORVITAMIN+D Search 19+NORVITAMIN+D
3 1 ALPHA 25 DIHYDROXYVITAMIN D 3 182470 3% 20% 54 Search 1+ALPHA+25+DIHYDROXYVITAMIN+D+3 Search 1+ALPHA+25+DIHYDROXYVITAMIN+D+3
4 CALCEMIC ACTIVITY 170286 1% 100% 10 Search CALCEMIC+ACTIVITY Search CALCEMIC+ACTIVITY
5 VITAMIN D RECEPTOR 163417 7% 8% 118 Search VITAMIN+D+RECEPTOR Search VITAMIN+D+RECEPTOR
6 ED 71 151699 1% 64% 14 Search ED+71 Search ED+71
7 19 NORVITAMIN D 3 119200 0% 100% 7 Search 19+NORVITAMIN+D+3 Search 19+NORVITAMIN+D+3
8 VDR BINDING AFFINITY 119200 0% 100% 7 Search VDR+BINDING+AFFINITY Search VDR+BINDING+AFFINITY
9 VDR BINDING 102171 0% 100% 6 Search VDR+BINDING Search VDR+BINDING
10 C 3 EPIMERIZATION PATHWAY 92708 0% 78% 7 Search C+3+EPIMERIZATION+PATHWAY Search C+3+EPIMERIZATION+PATHWAY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZHU, GD , OKAMURA, WH , (1995) SYNTHESIS OF VITAMIN-D (CALCIFEROL).CHEMICAL REVIEWS. VOL. 95. ISSUE 6. P. 1877 -1952 229 58% 293
2 FERNANDEZ, S , HERNANDEZ-MARTIN, A , GONZALEZ-GARCIA, T , FERRERO, M , (2014) SYNTHESIS OF 6-S-CIS AND 6-S-TRANS A-RING MODIFIED VITAMIN D ANALOGUES.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 14. ISSUE 21. P. 2424 -2445 105 86% 0
3 CARLBERG, C , MOLNAR, F , MOURINO, A , (2012) VITAMIN D RECEPTOR LIGANDS: THE IMPACT OF CRYSTAL STRUCTURES.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 22. ISSUE 4. P. 417-435 67 85% 18
4 SAITO, N , HONZAWA, S , KITTAKA, A , (2006) RECENT RESULTS ON A-RING MODIFICATION OF 1 ALPHA,25-DIHYDROXYVITAMIN D-3: DESIGN AND SYNTHESIS OF VDR-AGONISTS AND ANTAGONISTS WITH HIGH BIOLOGICAL ACTIVITY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 6. ISSUE 12. P. 1273 -1288 82 85% 6
5 CHAPELON, AS , MORALEDA, D , RODRIGUEZ, R , OLLIVIER, C , SANTELLI, M , (2007) ENANTIOSELECTIVE SYNTHESIS OF STEROIDS.TETRAHEDRON. VOL. 63. ISSUE 47. P. 11511 -11616 132 47% 39
6 BOUILLON, R , OKAMURA, WH , NORMAN, AW , (1995) STRUCTURE-FUNCTION-RELATIONSHIPS IN THE VITAMIN-D ENDOCRINE SYSTEM.ENDOCRINE REVIEWS. VOL. 16. ISSUE 2. P. 200-257 142 33% 966
7 ZHANG, CF , LIU, ZP , (2013) RECENT DEVELOPMENTS OF 2-SUBSTITUTED ANALOGS OF 1,25(OH)(2)D-3.CURRENT MEDICINAL CHEMISTRY. VOL. 20. ISSUE 16. P. 2080 -2095 68 84% 2
8 GLEBOCKA, A , CHIELLINI, G , (2012) A-RING ANALOGS OF 1,25-DIHYDROXYVITAMIN D-3.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 523. ISSUE 1. P. 48-57 67 68% 5
9 KITTAKA, A , (2008) STRUCTURAL REFINEMENT OF SECO-STEROIDAL SKELETON AND THE BIOLOGICAL ACTIVITY THROUGH NUCLEAR RECEPTORS.YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. VOL. 128. ISSUE 9. P. 1235 -1250 56 90% 1
10 KONNO, K , FUJISHIMA, T , MAKI, S , LIU, ZP , MIURA, D , CHOKKI, M , ISHIZUKA, S , YAMAGUCHI, K , KAN, Y , KURIHARA, M , ET AL (2000) SYNTHESIS, BIOLOGICAL EVALUATION, AND CONFORMATIONAL ANALYSIS OF A-RING DIASTEREOMERS OF 2-METHYL-1,25-DIHYDROXYVITAMIN D-3 AND THEIR 20-EPIMERS: UNIQUE ACTIVITY PROFILES DEPENDING ON THE STEREOCHEMISTRY OF THE A-RING AND AT C-20.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 43. ISSUE 22. P. 4247 -4265 62 87% 47

Classes with closest relation at Level 1


Rank Class id link
1 16455 DEQAS//25 HYDROXYVITAMIN D 3//3 EPI 25 HYDROXYVITAMIN D 3
2 15377 CYP27B1//VITAMIN D HYDROXYLASES//ENDOCRINE BONE
3 4108 24 25OH2D 3//HEREDITARY VITAMIN D RESISTANT RICKETS//1 ALPHA 25OH2D 3
4 1610 VITAMIN D//VITAMIN D RECEPTOR//VDR
5 14748 ALFACALCIDOL//ELDECALCITOL//ED 71
6 14075 O QUINODIMETHANE//ORTHO QUINODIMETHANES//ANGULAR TRIFLUOROMETHYL GROUP
7 8508 HUMAN PLACENTAL MICROSOMES//19 OXYGENATION//SUICIDE SUBSTRATE
8 32550 1 3 BIPOLAR CYCLOADDITION OF NITRILE OXIDES//17 20 DIOLS//17 ALPHA PREGNA 2 4 DIEN 2 3 DISOXAZOL 17 BETA OL
9 7545 CALCIPOTRIOL//BETAMETHASONE DIPROPIONATE//TACALCITOL
10 17222 VITAMIN D BINDING PROTEIN//GC GLOBULIN//GCMAF

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