Class information for:
Level 1: AKAP//A KINASE ANCHORING PROTEIN//GRAVIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11840 950 50.4 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
343 3       NITRIC OXIDE//PEROXYNITRITE//NITRIC OXIDE SYNTHASE 36678
1338 2             PHOSPHODIESTERASE//ROLIPRAM//PDE4 8346
11840 1                   AKAP//A KINASE ANCHORING PROTEIN//GRAVIN 950

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AKAP authKW 1221485 8% 49% 77
2 A KINASE ANCHORING PROTEIN authKW 902793 5% 56% 50
3 GRAVIN authKW 772618 3% 96% 25
4 A KINASE ANCHORING PROTEIN AKAP authKW 528617 3% 66% 25
5 SSECKS authKW 485772 2% 66% 23
6 AKAP12 authKW 401757 2% 83% 15
7 SRC SUPPRESSED C KINASE SUBSTRATE authKW 257128 1% 100% 8
8 MAKAP authKW 228556 1% 89% 8
9 DIPARTIMENTO BIOL PATOL MOL CELLULARE address 181046 1% 43% 13
10 AKAPS authKW 162706 1% 56% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 2978 29% 0% 280
2 Biochemistry & Molecular Biology 2510 44% 0% 415
3 Cardiac & Cardiovascular System 662 11% 0% 109
4 Peripheral Vascular Diseases 335 6% 0% 59
5 Physiology 203 6% 0% 57
6 Hematology 167 5% 0% 46
7 Biophysics 84 5% 0% 43
8 Pharmacology & Pharmacy 82 8% 0% 77
9 Neurosciences 58 7% 0% 69
10 Developmental Biology 40 2% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIPARTIMENTO BIOL PATOL MOL CELLULARE 181046 1% 43% 13
2 CARDIAC SIGNAL TRANSDUCT CELLULAR BIOL 131236 1% 58% 7
3 VOLLUM 125919 7% 6% 69
4 ATRAN S 120993 1% 47% 8
5 EUROPEAN HEART GOTTINGEN 96423 0% 100% 3
6 MOL MED NORWAY 81106 2% 13% 19
7 INTERDISCIPLINARY STEM CELL PEDIAT 73462 0% 57% 4
8 EUROPEAN HEART INSITUTE GOTTINGEN 72316 0% 75% 3
9 IST ENDOCRINOL ONCOL SPERIMENTALEBIOGEM CONSORT 64282 0% 100% 2
10 INTERDISCIPLINARY STEM CELL MED 57851 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 3586 14% 0% 132
2 CIRCULATION RESEARCH 3426 3% 0% 33
3 CELLULAR SIGNALLING 2923 2% 0% 20
4 FRONTIERS IN PHARMACOLOGY 2050 1% 1% 10
5 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 1759 2% 0% 19
6 BIOCHEMICAL SOCIETY TRANSACTIONS 1572 2% 0% 23
7 BRAIN CELL BIOLOGY 916 0% 3% 1
8 EUROPEAN JOURNAL OF CELL BIOLOGY 795 1% 0% 10
9 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 735 1% 0% 13
10 PHYSIOLOGY 611 0% 1% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AKAP 1221485 8% 49% 77 Search AKAP Search AKAP
2 A KINASE ANCHORING PROTEIN 902793 5% 56% 50 Search A+KINASE+ANCHORING+PROTEIN Search A+KINASE+ANCHORING+PROTEIN
3 GRAVIN 772618 3% 96% 25 Search GRAVIN Search GRAVIN
4 A KINASE ANCHORING PROTEIN AKAP 528617 3% 66% 25 Search A+KINASE+ANCHORING+PROTEIN+AKAP Search A+KINASE+ANCHORING+PROTEIN+AKAP
5 SSECKS 485772 2% 66% 23 Search SSECKS Search SSECKS
6 AKAP12 401757 2% 83% 15 Search AKAP12 Search AKAP12
7 SRC SUPPRESSED C KINASE SUBSTRATE 257128 1% 100% 8 Search SRC+SUPPRESSED+C+KINASE+SUBSTRATE Search SRC+SUPPRESSED+C+KINASE+SUBSTRATE
8 MAKAP 228556 1% 89% 8 Search MAKAP Search MAKAP
9 AKAPS 162706 1% 56% 9 Search AKAPS Search AKAPS
10 AKAP95 157487 1% 70% 7 Search AKAP95 Search AKAP95

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SCOTT, JD , DESSAUER, CW , TASKEN, K , (2013) CREATING ORDER FROM CHAOS: CELLULAR REGULATION BY KINASE ANCHORING.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013. VOL. 53. ISSUE . P. 187-210 107 60% 52
2 WELCH, EJ , JONES, BW , SCOTT, JD , (2010) NETWORKING WITH AKAPS: CONTEXT-DEPENDENT REGULATION OF ANCHORED ENZYMES.MOLECULAR INTERVENTIONS. VOL. 10. ISSUE 2. P. 86-97 109 67% 72
3 SKROBLIN, P , GROSSMANN, S , SCHAFER, G , ROSENTHAL, W , KLUSSMANN, E , (2010) MECHANISMS OF PROTEIN KINASE A ANCHORING.INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 283. VOL. 283. ISSUE . P. 235 -330 195 38% 49
4 TROGER, J , MOUTTY, MC , SKROBLIN, P , KLUSSMANN, E , (2012) A-KINASE ANCHORING PROTEINS AS POTENTIAL DRUG TARGETS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 166. ISSUE 2. P. 420 -433 86 61% 28
5 DEMA, A , PERETS, E , SCHULZ, MS , DEAK, VA , KLUSSMANN, E , (2015) PHARMACOLOGICAL TARGETING OF AKAP-DIRECTED COMPARTMENTALIZED CAMP SIGNALLING.CELLULAR SIGNALLING. VOL. 27. ISSUE 12. P. 2474 -2487 109 48% 3
6 DEAK, VA , KLUSSMANN, E , (2016) PHARMACOLOGICAL INTERFERENCE WITH PROTEIN-PROTEIN INTERACTIONS OF AKINASE ANCHORING PROTEINS AS A STRATEGY FOR THE TREATMENT OF DISEASE.CURRENT DRUG TARGETS. VOL. 17. ISSUE 10. P. 1147 -1171 111 46% 0
7 CALEJO, AI , TASKEN, K , (2015) TARGETING PROTEIN-PROTEIN INTERACTIONS IN COMPLEXES ORGANIZED BY A KINASE ANCHORING PROTEINS.FRONTIERS IN PHARMACOLOGY. VOL. 6. ISSUE . P. - 75 64% 2
8 KRITZER, MD , LI, JL , DODGE-KAFKA, K , KAPILOFF, MS , (2012) AKAPS: THE ARCHITECTURAL UNDERPINNINGS OF LOCAL CAMP SIGNALING.JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. VOL. 52. ISSUE 2. P. 351 -358 66 63% 34
9 GOTZ, F , ROSKE, Y , SCHULZ, MS , AUTENRIETH, K , BERTINETTI, D , FAELBER, K , ZUHLKE, K , KREUCHWIG, A , KENNEDY, EJ , KRAUSE, G , ET AL (2016) AKAP18:PKA-RII ALPHA STRUCTURE REVEALS CRUCIAL ANCHOR POINTS FOR RECOGNITION OF REGULATORY SUBUNITS OF PKA.BIOCHEMICAL JOURNAL. VOL. 473. ISSUE . P. 1881 -1894 45 87% 0
10 PIDOUX, G , TASKEN, K , (2010) SPECIFICITY AND SPATIAL DYNAMICS OF PROTEIN KINASE A SIGNALING ORGANIZED BY A-KINASE-ANCHORING PROTEINS.JOURNAL OF MOLECULAR ENDOCRINOLOGY. VOL. 44. ISSUE 5. P. 271 -284 59 61% 69

Classes with closest relation at Level 1


Rank Class id link
1 3603 CELLULAR BIOCHEM SECT//CAMP DEPENDENT PROTEIN KINASE//8 CHLORO ADENOSINE
2 10163 ADENYLYL CYCLASE//ABT PHARMAZEUT BIOCHEM//ADENYLYL CYCLASE ISOFORMS
3 11178 RAP1//EPAC//EPAC1
4 658 ROLIPRAM//PHOSPHODIESTERASE//PDE4
5 19890 SILDENAFIL//PDE5//PDE 5 INHIBITION
6 5929 CALCIUM SIGNALS//TIMOTHY SYNDROME//CAV12
7 33774 CANC MICROARRAY GENES PROT//SPERM PROTEIN 17//SPAG9
8 6581 BETA ADRENOCEPTOR//BETA ADRENERGIC RECEPTOR SUBTYPES//BETA ADRENERGIC RECEPTOR
9 16151 CGMP DEPENDENT PROTEIN KINASE//TYPE II CGMP DEPENDENT PROTEIN KINASE//CANC MOL BIOL SECT
10 2285 G PROTEIN COUPLED RECEPTOR KINASE//ARRESTIN//BETA ARRESTIN

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