Class information for:
Level 1: RECOMBINANT ACTIVATED FACTOR VII//RECOMBINANT FACTOR VIIA//RFVIIA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11335 990 30.8 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
131 3       HEMATOLOGY//HAEMOPHILIA//TRANSFUSION 66936
767 2             WARFARIN//CYP2C9//VKORC1 12292
11335 1                   RECOMBINANT ACTIVATED FACTOR VII//RECOMBINANT FACTOR VIIA//RFVIIA 990

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RECOMBINANT ACTIVATED FACTOR VII authKW 2079694 12% 57% 119
2 RECOMBINANT FACTOR VIIA authKW 1546386 12% 43% 117
3 RFVIIA authKW 1291702 10% 42% 99
4 NOVOSEVEN authKW 692152 4% 61% 37
5 FACTOR VIIA authKW 563377 8% 23% 78
6 RECOMBINANT ACTIVATED FACTOR VII RFVIIA authKW 440592 2% 71% 20
7 RECOMBINANT FVIIA authKW 232747 2% 38% 20
8 RECOMBINANT FACTOR VLLA authKW 215896 1% 100% 7
9 RECOMBINANT ACTIVATED FACTOR VIIA authKW 207320 1% 61% 11
10 RECOMBINANT FACTOR VII authKW 156131 1% 56% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 17132 40% 0% 397
2 Anesthesiology 4223 13% 0% 125
3 Peripheral Vascular Diseases 2607 16% 0% 154
4 Critical Care Medicine 2566 10% 0% 101
5 Surgery 643 15% 0% 153
6 Respiratory System 512 6% 0% 64
7 Cardiac & Cardiovascular System 311 8% 0% 81
8 Pediatrics 234 6% 0% 62
9 Emergency Medicine 188 2% 0% 20
10 Medicine, General & Internal 135 7% 0% 70

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SO ALBERTA HEMOPHILIA CLIN 70091 1% 45% 5
2 COAGULAT ADVANCEMENT 69394 0% 75% 3
3 BIOPHARMACEUT UNIT 64286 1% 15% 14
4 INTERDISZIPLINARE INTERNIST INTENSIVMED 61685 0% 100% 2
5 CENT VIRGINIA COAGULAT DISORDERS 59306 1% 38% 5
6 EXPLORATORY ADME 45349 1% 29% 5
7 HAEMOSTASIS BIOL 42829 1% 28% 5
8 NOVO NORDISK PK 41122 0% 67% 2
9 ZENTRUM HAMOSTASEOL 41122 0% 67% 2
10 HAEMOSTASIS PHARMACOL 32893 0% 27% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD COAGULATION & FIBRINOLYSIS 61649 8% 2% 81
2 SEMINARS IN HEMATOLOGY 7830 2% 1% 22
3 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 7540 3% 1% 31
4 HAEMOPHILIA 3217 2% 1% 18
5 JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA 3198 2% 1% 20
6 THROMBOSIS AND HAEMOSTASIS 3125 3% 0% 32
7 SRPSKI ARHIV ZA CELOKUPNO LEKARSTVO 2766 1% 1% 10
8 CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 2271 1% 1% 11
9 PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS 2126 1% 1% 5
10 JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE 2035 3% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RECOMBINANT ACTIVATED FACTOR VII 2079694 12% 57% 119 Search RECOMBINANT+ACTIVATED+FACTOR+VII Search RECOMBINANT+ACTIVATED+FACTOR+VII
2 RECOMBINANT FACTOR VIIA 1546386 12% 43% 117 Search RECOMBINANT+FACTOR+VIIA Search RECOMBINANT+FACTOR+VIIA
3 RFVIIA 1291702 10% 42% 99 Search RFVIIA Search RFVIIA
4 NOVOSEVEN 692152 4% 61% 37 Search NOVOSEVEN Search NOVOSEVEN
5 FACTOR VIIA 563377 8% 23% 78 Search FACTOR+VIIA Search FACTOR+VIIA
6 RECOMBINANT ACTIVATED FACTOR VII RFVIIA 440592 2% 71% 20 Search RECOMBINANT+ACTIVATED+FACTOR+VII+RFVIIA Search RECOMBINANT+ACTIVATED+FACTOR+VII+RFVIIA
7 RECOMBINANT FVIIA 232747 2% 38% 20 Search RECOMBINANT+FVIIA Search RECOMBINANT+FVIIA
8 RECOMBINANT FACTOR VLLA 215896 1% 100% 7 Search RECOMBINANT+FACTOR+VLLA Search RECOMBINANT+FACTOR+VLLA
9 RECOMBINANT ACTIVATED FACTOR VIIA 207320 1% 61% 11 Search RECOMBINANT+ACTIVATED+FACTOR+VIIA Search RECOMBINANT+ACTIVATED+FACTOR+VIIA
10 RECOMBINANT FACTOR VII 156131 1% 56% 9 Search RECOMBINANT+FACTOR+VII Search RECOMBINANT+FACTOR+VII

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PHILLIPS, LE , ZATTA, AJ , SCHEMBRI, NL , NOONE, AK , ISBISTER, J , (2009) UNCONTROLLED BLEEDING IN SURGICAL PATIENTS: THE ROLE OF RECOMBINANT ACTIVATED FACTOR VIIA.CURRENT DRUG TARGETS. VOL. 10. ISSUE 8. P. 744-770 173 92% 3
2 MALLARKEY, G , BRIGHTON, T , THOMSON, A , KAYE, K , SEALE, P , GAZARIAN, M , (2008) AN EVALUATION OF EPTACOG ALFA IN NONHAEMOPHILIAC CONDITIONS.DRUGS. VOL. 68. ISSUE 12. P. 1665-1689 89 92% 12
3 YANK, V , TUOHY, CV , LOGAN, AC , BRAVATA, DM , STAUDENMAYER, K , EISENHUT, R , SUNDARAM, V , MCMAHON, D , OLKIN, I , MCDONALD, KM , ET AL (2011) SYSTEMATIC REVIEW: BENEFITS AND HARMS OF IN-HOSPITAL USE OF RECOMBINANT FACTOR VIIA FOR OFF-LABEL INDICATIONS.ANNALS OF INTERNAL MEDICINE. VOL. 154. ISSUE 8. P. 529 -540 63 74% 103
4 HONG, I , STACHNIK, J , (2010) UNLABELED USES OF FACTOR VIIA (RECOMBINANT) IN PEDIATRIC PATIENTS.AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY. VOL. 67. ISSUE 22. P. 1909-1919 62 94% 3
5 SIMPSON, E , LIN, YL , STANWORTH, S , BIRCHALL, J , DOREE, C , HYDE, C , (2012) RECOMBINANT FACTOR VIIA FOR THE PREVENTION AND TREATMENT OF BLEEDING IN PATIENTS WITHOUT HAEMOPHILIA.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 3. P. - 68 77% 9
6 FRANCHINI, M , (2006) RECOMBINANT FACTOR VIIA: A REVIEW ON ITS CLINICAL USE.INTERNATIONAL JOURNAL OF HEMATOLOGY. VOL. 83. ISSUE 2. P. 126-138 96 60% 14
7 RAMA-MACEIRAS, P , INGELMO-INGELMO, I , FABREGAS-JULIA, N , HERNANDEZ-PALAZON, J , (2011) THE ROLE OF RECOMBINANT ACTIVATED FACTOR VII IN NEUROSURGICAL AND NEUROCRITICAL PATIENTS.NEUROCIRUGIA. VOL. 22. ISSUE 3. P. 209-223 75 65% 1
8 FRANCHINI, M , ZAFFANELLO, M , VENERI, D , (2005) RECOMBINANT FACTOR VIIA - AN UPDATE ON ITS CLINICAL USE.THROMBOSIS AND HAEMOSTASIS. VOL. 93. ISSUE 6. P. 1027-1035 81 62% 48
9 GUZZETTA, NA , RUSSELL, IA , WILLIAMS, GD , (2012) REVIEW OF THE OFF-LABEL USE OF RECOMBINANT ACTIVATED FACTOR VII IN PEDIATRIC CARDIAC SURGERY PATIENTS.ANESTHESIA AND ANALGESIA. VOL. 115. ISSUE 2. P. 364-378 57 76% 10
10 LIN, YL , STANWORTH, S , BIRCHALL, J , DOREE, C , HYDE, C , (2011) RECOMBINANT FACTOR VIIA FOR THE PREVENTION AND TREATMENT OF BLEEDING IN PATIENTS WITHOUT HAEMOPHILIA.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 2. P. - 50 81% 12

Classes with closest relation at Level 1


Rank Class id link
1 19162 PROTHROMBIN COMPLEX CONCENTRATE//ANTICOAGULATION REVERSAL//WARFARIN REVERSAL
2 2067 FACTOR VIII INHIBITOR//HAEMOPHILIA//ACQUIRED HAEMOPHILIA
3 1448 MASSIVE TRANSFUSION//THROMBOELASTOGRAPHY//THROMBOELASTOMETRY
4 17915 THROMBIN GENERATION//THROMBIN GENERATION ASSAY//ENDOGENOUS THROMBIN POTENTIAL
5 17027 FACTOR VII DEFICIENCY//FACTOR X DEFICIENCY//FVII DEFICIENCY
6 16961 SECT HEPATOBILIARY SURG LIVER TRANSPLANTAT//COAGULAT LIVER DIS STUDY GRP//BLOOD COAGULATION DISORDERS ETIOLOGY THERAPY
7 3682 APROTININ//TRANEXAMIC ACID//ANTIFIBRINOLYTIC AGENTS
8 942 TISSUE FACTOR//TISSUE FACTOR PATHWAY INHIBITOR//TFPI
9 1357 INTRACEREBRAL HEMORRHAGE//CEREBRAL HEMORRHAGE//HEMATOMA EXPANSION
10 22060 DESMOPRESSIN//DDAVP//PHARMACOLOGY DESMOPRESSIN

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