Class information for:
Level 1: PROTHROMBIN COMPLEX CONCENTRATE//ANTICOAGULATION REVERSAL//WARFARIN REVERSAL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19162 519 30.0 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
131 3       HEMATOLOGY//HAEMOPHILIA//TRANSFUSION 66936
767 2             WARFARIN//CYP2C9//VKORC1 12292
19162 1                   PROTHROMBIN COMPLEX CONCENTRATE//ANTICOAGULATION REVERSAL//WARFARIN REVERSAL 519

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTHROMBIN COMPLEX CONCENTRATE authKW 3544681 23% 50% 121
2 ANTICOAGULATION REVERSAL authKW 579275 3% 62% 16
3 WARFARIN REVERSAL authKW 529505 2% 100% 9
4 ACTIVATED FACTORS authKW 176502 1% 100% 3
5 ORAL ANTICOAGULANT REVERSAL authKW 176502 1% 100% 3
6 WARFARIN authKW 140695 18% 3% 95
7 FACTOR IX COMPLEX authKW 134474 1% 57% 4
8 HEMOPHILIA CRIT CARE address 132375 1% 75% 3
9 OCTAPLEX authKW 132375 1% 75% 3
10 ASESORIA CIENT address 117668 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 12846 48% 0% 248
2 Peripheral Vascular Diseases 3186 23% 0% 121
3 Emergency Medicine 974 6% 0% 31
4 Critical Care Medicine 565 7% 0% 35
5 Anesthesiology 464 6% 0% 31
6 Medicine, General & Internal 151 9% 0% 49
7 Pharmacology & Pharmacy 45 8% 0% 42
8 Surgery 19 6% 0% 29
9 Clinical Neurology 18 4% 0% 22
10 Medical Laboratory Technology 9 1% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMOPHILIA CRIT CARE 132375 1% 75% 3
2 ASESORIA CIENT 117668 0% 100% 2
3 ST JOSEPH REG HLTH 117668 0% 100% 2
4 SETON UT SOUTHWESTERN CLIN AUSTIN 88248 1% 50% 3
5 DELL CHILDRENS MED 73535 1% 25% 5
6 TRANSFUS MED HEMOSTASIS 66849 1% 23% 5
7 ABT KLIN HAMOSTASIOL TRANSFUS MED 58834 0% 100% 1
8 ALZAHRA HEART HOSP 58834 0% 100% 1
9 ANESTHESIOL INTENS CARE MED PAIN MANAGEM 58834 0% 100% 1
10 AREA SANITARIA ALBACETE 58834 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THROMBOSIS RESEARCH 11112 8% 0% 44
2 THROMBOSIS AND HAEMOSTASIS 7207 7% 0% 35
3 BLOOD COAGULATION & FIBRINOLYSIS 4569 3% 0% 16
4 JOURNAL OF THROMBOSIS AND THROMBOLYSIS 3828 2% 1% 11
5 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 2524 3% 0% 13
6 BLOOD TRANSFUSION 2332 1% 1% 5
7 VOX SANGUINIS 2145 2% 0% 12
8 SEMINARS IN HEMATOLOGY 1970 2% 0% 8
9 HAEMOPHILIA 1533 2% 0% 9
10 NEUROCRITICAL CARE 1415 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROTHROMBIN COMPLEX CONCENTRATE 3544681 23% 50% 121 Search PROTHROMBIN+COMPLEX+CONCENTRATE Search PROTHROMBIN+COMPLEX+CONCENTRATE
2 ANTICOAGULATION REVERSAL 579275 3% 62% 16 Search ANTICOAGULATION+REVERSAL Search ANTICOAGULATION+REVERSAL
3 WARFARIN REVERSAL 529505 2% 100% 9 Search WARFARIN+REVERSAL Search WARFARIN+REVERSAL
4 ACTIVATED FACTORS 176502 1% 100% 3 Search ACTIVATED+FACTORS Search ACTIVATED+FACTORS
5 ORAL ANTICOAGULANT REVERSAL 176502 1% 100% 3 Search ORAL+ANTICOAGULANT+REVERSAL Search ORAL+ANTICOAGULANT+REVERSAL
6 WARFARIN 140695 18% 3% 95 Search WARFARIN Search WARFARIN
7 FACTOR IX COMPLEX 134474 1% 57% 4 Search FACTOR+IX+COMPLEX Search FACTOR+IX+COMPLEX
8 OCTAPLEX 132375 1% 75% 3 Search OCTAPLEX Search OCTAPLEX
9 CONCENTRATES HIGHLY PURIFIED 117668 0% 100% 2 Search CONCENTRATES+HIGHLY+PURIFIED Search CONCENTRATES+HIGHLY+PURIFIED
10 FACTOR IX COMPLEX CONCENTRATE 117668 0% 100% 2 Search FACTOR+IX+COMPLEX+CONCENTRATE Search FACTOR+IX+COMPLEX+CONCENTRATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FRUMKIN, K , (2013) RAPID REVERSAL OF WARFARIN-ASSOCIATED HEMORRHAGE IN THE EMERGENCY DEPARTMENT BY PROTHROMBIN COMPLEX CONCENTRATES.ANNALS OF EMERGENCY MEDICINE. VOL. 62. ISSUE 6. P. 616-626 60 60% 5
2 GALSTYAN, GM , (2012) HEMOSTASIS DISORDERS CAUSED BY DEFICIENCY OF VITAMIN K-DEPENDENT COAGULATION FACTORS: PATHOGENESIS, CORRECTION METHODS AND RECOMMENDATIONS FOR TREATMENT.GEMATOLOGIYA I TRANSFUZIOLOGIYA. VOL. 57. ISSUE 2. P. 7 -21 48 66% 0
3 SIN, JH , BERGER, K , LESCH, CA , (2016) FOUR-FACTOR PROTHROMBIN COMPLEX CONCENTRATE FOR LIFE-THREATENING BLEEDS OR EMERGENT SURGERY: A RETROSPECTIVE EVALUATION.JOURNAL OF CRITICAL CARE. VOL. 36. ISSUE . P. 166 -172 39 71% 0
4 DENTALI, F , AGENO, W , CROWTHER, M , (2006) TREATMENT OF COUMARIN-ASSOCIATED COAGULOPATHY: A SYSTEMATIC REVIEW AND PROPOSED TREATMENT ALGORITHMS.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 4. ISSUE 9. P. 1853-1863 38 76% 61
5 DENTALI, F , MARCHESI, C , PIERFRANCESCHI, MG , CROWTHER, M , GARCIA, D , HYLEK, E , WITT, DM , CLARK, NP , SQUIZZATO, A , IMBERTI, D , ET AL (2011) SAFETY OF PROTHROMBIN COMPLEX CONCENTRATES FOR RAPID ANTICOAGULATION REVERSAL OF VITAMIN K ANTAGONISTS A META-ANALYSIS.THROMBOSIS AND HAEMOSTASIS. VOL. 106. ISSUE 3. P. 429 -438 27 69% 130
6 SORENSEN, B , SPAHN, DR , INNERHOFER, P , SPANNAGL, M , ROSSAINT, R , (2011) CLINICAL REVIEW: PROTHROMBIN COMPLEX CONCENTRATES - EVALUATION OF SAFETY AND THROMBOGENICITY.CRITICAL CARE. VOL. 15. ISSUE 1. P. - 31 65% 97
7 KHORSAND, N , KOOISTRA, HAM , VAN HEST, RM , VEEGER, NJGM , MEIJER, K , (2015) A SYSTEMATIC REVIEW OF PROTHROMBIN COMPLEX CONCENTRATE DOSING STRATEGIES TO REVERSE VITAMIN K ANTAGONIST THERAPY.THROMBOSIS RESEARCH. VOL. 135. ISSUE 1. P. 9 -19 27 79% 7
8 BERSHAD, EM , SUAREZ, JI , (2010) PROTHROMBIN COMPLEX CONCENTRATES FOR ORAL ANTICOAGULANT THERAPY-RELATED INTRACRANIAL HEMORRHAGE: A REVIEW OF THE LITERATURE.NEUROCRITICAL CARE. VOL. 12. ISSUE 3. P. 403 -413 37 60% 52
9 KHORSAND, N , MAJEED, A , SARODE, R , BEYER-WESTENDORF, J , SCHULMAN, S , MEIJER, K , (2016) ASSESSMENT OF EFFECTIVENESS OF MAJOR BLEEDING MANAGEMENT: PROPOSED DEFINITIONS FOR EFFECTIVE HEMOSTASIS: COMMUNICATION FROM THE SSC OF THE ISTH.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 14. ISSUE 1. P. 211 -214 23 82% 2
10 RODGERS, GM , (2012) PROTHROMBIN COMPLEX CONCENTRATES IN EMERGENCY BLEEDING DISORDERS.AMERICAN JOURNAL OF HEMATOLOGY. VOL. 87. ISSUE 9. P. 898-902 29 74% 16

Classes with closest relation at Level 1


Rank Class id link
1 11335 RECOMBINANT ACTIVATED FACTOR VII//RECOMBINANT FACTOR VIIA//RFVIIA
2 5951 INTERNATIONAL NORMALIZED RATIO//PROTHROMBIN TIME//INR
3 14295 HAEMOPHILIA//HEMOPHILIA//ANTIVIRAL HEAT TREATMENT
4 1357 INTRACEREBRAL HEMORRHAGE//CEREBRAL HEMORRHAGE//HEMATOMA EXPANSION
5 1448 MASSIVE TRANSFUSION//THROMBOELASTOGRAPHY//THROMBOELASTOMETRY
6 8566 BRIDGING THERAPY//BRIDGING ANTICOAGULATION//PERIOPERATIVE ANTICOAGULATION
7 58 DABIGATRAN//RIVAROXABAN//APIXABAN
8 33925 MEYERSON PHENOMENON//HALO DERMATITIS//MEYERSONS NEVUS
9 1342 HAEMOPHILIA//HEMOPHILIA//VAN CREVELDKLIN
10 9331 PATHOGEN INACTIVATION//AMOTOSALEN//SOLVENT DETERGENT

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