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Headings denoted with an asterisk ( * ) is retrieved from the course syllabus version Autumn 2021
Content and learning outcomes
Course contents
The course in Clinical Applications of Biotechnology provides an orientation on biotechnological methods and measurements used in healthcare. The course provides both theoretical background and practical application of analytical methods. The course includes basic knowledge of molecular disease mechanisms, biomarkers, molecular biology tools and methods. New developments with the potential to be integrated in a clinical context are highlighted. The course includes ethics and sustainability.
Intended learning outcomes
Knowledge and understanding
After passing the course the student must be able to:
Describe basic concepts regarding the main parts of the course.
In text, explain basic principles for biotechnological methods and measurements of biological samples.
Give examples of clinical applications of biotechnology.
Skills and abilities
After passing the course the student must be able to:
Relate biotechnological applications with underlying molecular disease mechanisms.
Be able to apply diagnostic measurements and report results in writing and orally.
Values and approaches
After passing the course the student must be able to:
Suggest biotechnological applications for clinical use and explain their benefits and disadvantages.
Reflect on the clinical use of biotechnology from an ethical, economic, ecological, and social perspective.
Detailed plan
Learning activities
Content
Preparations
Lectures (14)
Major examples, clinical applications in breast cancer, cardiovascular and hemostatic diseases, Microfluicis in nanobiotechnology, and societal impact.
Text book "Medical Biotechnology", by Glick, Delowitch, Patten, according to Reading assignement.
Scientific quizzes (6)
Quizzes on scientific articles
Read corresponding scientific articles
Midterm quiz
Covers the first half of the course
Attend lectures, complete scientific quizzes, read text book.
White paper
Group work on selected topic.
Select topic and work in groups
Presentation
Present white paper
Completed white paper
LAB1
Microfluidics for cancer cell separation, lab report (group)
Read preparatory material
LAB2
Determine biomarker and suggest treatment for breast cancer. Individual lab reports, peer review.
LAB1 - Laboratory work, 1.5 credits, Grading scale: P, F
LAB2 - Laboratory work, 1.5 credits, Grading scale: P, F
TEN1 - Written exam, 4.5 credits, Grading scale: A, B, C, D, E, FX, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
Other requirements for final grade
There are elements with compulsory attendance.
Ethical approach
All members of a group are responsible for the group's work.
In any assessment, every student shall honestly disclose any help received and sources used.
In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.
