Biocatalysis and Structural Biochemistry
Enzymes can be tailor-made, combined and used as powerful machines for production of biofuels, green chemicals and new materials from biomass resources. We are learning from nature and studying how to engineer and optimize enzymes for industrial-scale production of valuable chemicals ranging from functional monomers to active pharmaceutical ingredients.
Examples of our research include:
- A sustainable future needs bio-based polymers and materials. Our research focuses on basic and applied selective enzyme catalysis in combination with enzyme engineering. We are developing enzyme-based selective and efficient routes towards functional bio-based polymers.
- Development of sustainable routes towards manufacturing fine and commodity chemicals by implementing enzyme cascades that have the potential to transform biocatalysis into a future technology for green chemistry.
- Structural biology studies how proteins work. Our research on structure-function relationships increases knowledge on important biological and biotechnological processes, such as microbial diseases in plants and humans, and efficient use of biomass resources in a circular bioeconomy.
- Molecular biology and bioinformatics helps to understand transcriptional regulatory networks in plants. We draw inspiration from nature to design synthetic transcription circuits to enhance plant growth and adaptation.
In addition to our own research infrastructure, we also use the following KTH- and national infrastructures: MAXIV, Cryo-EM Sweden, 3D-EM, NMR, SciLifeLab PSF.