Class information for:
Level 2: PROTEOGLYCAN//HEPARANASE//HEPARAN SULFATE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
794 12111 43.0 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
250 3       OSTEOARTHRITIS//OSTEOARTHRITIS AND CARTILAGE//CHONDROCYTE 46264
794 2             PROTEOGLYCAN//HEPARANASE//HEPARAN SULFATE 12111
1305 1                   HEPARAN SULFATE//GLYCOSAMINOGLYCANS//HEPAROSAN 2728
6202 1                   SYNDECAN 1//SYNDECAN//SYNDECAN 4 1514
6302 1                   DECORIN//BIGLYCAN//LUMICAN 1502
7748 1                   PERINEURONAL NET//VERSICAN//CHONDROITIN SULFATE PROTEOGLYCAN 1332
11020 1                   PROTEOGLYCAN SIGNALING THER EUT//CHONDROITIN SULFATE//XYLOSYLTRANSFERASE 1015
11814 1                   SULODEXIDE//HEPARIN//INHALED HEPARIN 952
12697 1                   HEPARANASE//CANC VASC BIOL//HEPARANASE INHIBITOR 887
13560 1                   CELL BIOL DIABET//DIABET CELL BIOL//PROTEOGLYCAN 828
20445 1                   PERLECAN//SCHWARTZ JAMPEL SYNDROME//STUVE WIEDEMANN SYNDROME 460
25209 1                   SERGLYCIN//SERGLYCIN PROTEOGLYCAN//ANAG 287
26139 1                   RGTA//DERIVATIZED DEXTRANS//DEXTRAN DERIVATIVES 262
30760 1                   ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//HEPARIN DERIVED OLIGOSACCHARIDE//NEUROPATHOL S 163
34003 1                   HEPARIN LIKE ANTICOAGULANTS//BIOCHEM PHYSIOL NUTR SCITORRE BIOL//COOKED SALTED MEATS 117
37209 1                   SULFATED HYALURONAN//HYALURONIC ACID HYALURONAN HA SULFATE//MAX BERGMANN BIOMAT 64

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 PROTEOGLYCAN authKW 879450 9% 32% 1095
2 HEPARANASE authKW 835449 3% 83% 399
3 HEPARAN SULFATE authKW 782083 5% 48% 645
4 GLYCOSAMINOGLYCANS authKW 703619 8% 29% 976
5 DECORIN authKW 498704 3% 56% 351
6 CHONDROITIN SULFATE authKW 359428 4% 33% 432
7 BIGLYCAN authKW 305569 1% 67% 181
8 SYNDECAN 1 authKW 292973 2% 63% 184
9 SYNDECAN authKW 290073 2% 60% 192
10 PERINEURONAL NET authKW 282109 1% 80% 140

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 23131 38% 0% 4598
2 Cell Biology 7901 15% 0% 1783
3 Peripheral Vascular Diseases 3122 5% 0% 658
4 Developmental Biology 1490 3% 0% 315
5 Hematology 1416 4% 0% 498
6 Biophysics 1314 5% 0% 591
7 Biochemical Research Methods 1199 4% 0% 518
8 Oncology 997 7% 0% 833
9 Chemistry, Analytical 942 5% 0% 645
10 Neurosciences 912 8% 0% 935

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC VASC BIOL 211704 1% 57% 147
2 CANC CELL BIOL SIGNALING PROGRAM 98703 0% 75% 52
3 PROTEOGLYCAN SIGNALING THER EUT 83023 0% 80% 41
4 MOL SCI MED 74067 1% 37% 79
5 BIOTECHNOL INTERDISCIPLINARY STUDIES 59358 1% 16% 146
6 MED BIOCHEM MICROBIOL 43927 1% 11% 161
7 SECT ORGAN CHEM BIOCHEM NAT PROD 42302 0% 41% 41
8 PATHOL ANAT CELL BIOL 32705 1% 9% 139
9 PERINATOL NEUROGLYCOSCI 30858 0% 88% 14
10 PROTEOGLYCAN SIGNALING THER EUTKITA KU 30232 0% 100% 12

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MATRIX BIOLOGY 32968 1% 10% 133
2 GLYCOBIOLOGY 32426 2% 7% 192
3 JOURNAL OF BIOLOGICAL CHEMISTRY 20201 9% 1% 1138
4 GLYCOCONJUGATE JOURNAL 16184 1% 6% 113
5 CARBOHYDRATE RESEARCH 8077 2% 2% 213
6 TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 7060 0% 7% 40
7 BIOCHEMICAL JOURNAL 6997 2% 1% 294
8 CONNECTIVE TISSUE RESEARCH 5889 1% 4% 65
9 ATHEROSCLEROSIS 4030 1% 1% 134
10 ANALYTICAL BIOCHEMISTRY 3481 1% 1% 166

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 PROTEOGLYCAN 879450 9% 32% 1095 Search PROTEOGLYCAN Search PROTEOGLYCAN
2 HEPARANASE 835449 3% 83% 399 Search HEPARANASE Search HEPARANASE
3 HEPARAN SULFATE 782083 5% 48% 645 Search HEPARAN+SULFATE Search HEPARAN+SULFATE
4 GLYCOSAMINOGLYCANS 703619 8% 29% 976 Search GLYCOSAMINOGLYCANS Search GLYCOSAMINOGLYCANS
5 DECORIN 498704 3% 56% 351 Search DECORIN Search DECORIN
6 CHONDROITIN SULFATE 359428 4% 33% 432 Search CHONDROITIN+SULFATE Search CHONDROITIN+SULFATE
7 BIGLYCAN 305569 1% 67% 181 Search BIGLYCAN Search BIGLYCAN
8 SYNDECAN 1 292973 2% 63% 184 Search SYNDECAN+1 Search SYNDECAN+1
9 SYNDECAN 290073 2% 60% 192 Search SYNDECAN Search SYNDECAN
10 PERINEURONAL NET 282109 1% 80% 140 Search PERINEURONAL+NET Search PERINEURONAL+NET

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 IOZZO, RV , SCHAEFER, L , (2015) PROTEOGLYCAN FORM AND FUNCTION: A COMPREHENSIVE NOMENCLATURE OF PROTEOGLYCANS.MATRIX BIOLOGY. VOL. 42. ISSUE . P. 11 -55 358 66% 42
2 RIVARA, S , MILAZZO, FM , GIANNINI, G , (2016) HEPARANASE: A RAINBOW PHARMACOLOGICAL TARGET ASSOCIATED TO MULTIPLE PATHOLOGIES INCLUDING RARE DISEASES.FUTURE MEDICINAL CHEMISTRY. VOL. 8. ISSUE 6. P. 647 -680 168 88% 6
3 IOZZO, RV , SANDERSON, RD , (2011) PROTEOGLYCANS IN CANCER BIOLOGY, TUMOUR MICROENVIRONMENT AND ANGIOGENESIS.JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. VOL. 15. ISSUE 5. P. 1013 -1031 195 77% 107
4 SANDERSON, RD , ELKIN, M , RAPRAEGER, AC , ILAN, N , VLODAVSKY, I , (2017) HEPARANASE REGULATION OF CANCER, AUTOPHAGY AND INFLAMMATION: NEW MECHANISMS AND TARGETS FOR THERAPY.FEBS JOURNAL. VOL. 284. ISSUE 1. P. 42 -55 100 71% 3
5 ESKO, JD , SELLECK, SB , (2002) ORDER OUT OF CHAOS: ASSEMBLY OF LIGAND BINDING SITES IN HEPARAN SULFATE.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 71. ISSUE . P. 435-471 168 69% 840
6 MULLOY, B , HOGWOOD, J , GRAY, E , LEVER, R , PAGE, CP , (2016) PHARMACOLOGY OF HEPARIN AND RELATED DRUGS.PHARMACOLOGICAL REVIEWS. VOL. 68. ISSUE 1. P. 76 -141 297 34% 8
7 THEOCHARIS, AD , SKANDALIS, SS , NEILL, T , MULTHAUPT, HAB , HUBO, M , FREY, H , GOPAL, S , GOMES, A , AFRATIS, N , LIM, HC , ET AL (2015) INSIGHTS INTO THE KEY ROLES OF PROTEOGLYCANS IN BREAST CANCER BIOLOGY AND TRANSLATIONAL MEDICINE.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1855. ISSUE 2. P. 276 -300 204 60% 12
8 SARRAZIN, S , LAMANNA, WC , ESKO, JD , (2011) HEPARAN SULFATE PROTEOGLYCANS.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 3. ISSUE 7. P. - 186 57% 172
9 LINDAHL, U , LI, JP , (2009) INTERACTIONS BETWEEN HEPARAN SULFATE AND PROTEINS-DESIGN AND FUNCTIONAL IMPLICATIONS.INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 276. VOL. 276. ISSUE . P. 105-159 195 68% 96
10 SCHAEFER, L , TREDUP, C , GUBBIOTTI, MA , IOZZO, RV , (2017) PROTEOGLYCAN NEOFUNCTIONS: REGULATION OF INFLAMMATION AND AUTOPHAGY IN CANCER BIOLOGY.FEBS JOURNAL. VOL. 284. ISSUE 1. P. 10 -26 88 63% 3

Classes with closest relation at Level 2


Rank Class id link
1 1856 CD44//HYALURONAN//HYALURONIC ACID
2 1927 FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21
3 3816 PROTAMINE//POLYION SENSORS//SIMULAT ENGN MOSE
4 2704 FUCOIDAN//CARRAGEENAN//SULFATED POLYSACCHARIDE
5 72 OSTEOARTHRITIS//OSTEOARTHRITIS AND CARTILAGE//CHONDROCYTE
6 3692 SPARC//OSTEONECTIN//JWA
7 1878 ALPORT SYNDROME//LAMININ//BASEMENT MEMBRANE
8 683 INTEGRIN//FOCAL ADHESION KINASE//TENASCIN C
9 572 PODOCYTE//NEPHRIN//KIDNEY INTERNATIONAL
10 2405 POLYSIALIC ACID//NCAM//NEURAL CELL ADHESION MOLECULE

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