Class information for:
Level 1: HEPARANASE//CANC VASC BIOL//HEPARANASE INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12697 887 43.8 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
250 3       OSTEOARTHRITIS//OSTEOARTHRITIS AND CARTILAGE//CHONDROCYTE 46264
794 2             PROTEOGLYCAN//HEPARANASE//HEPARAN SULFATE 12111
12697 1                   HEPARANASE//CANC VASC BIOL//HEPARANASE INHIBITOR 887

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEPARANASE authKW 10355716 43% 79% 380
2 CANC VASC BIOL address 2816075 16% 56% 145
3 HEPARANASE INHIBITOR authKW 489582 2% 89% 16
4 PI 88 authKW 432536 2% 74% 17
5 HEPARAN SULFATE authKW 272554 12% 8% 103
6 HEPARANASE 1 authKW 229486 1% 67% 10
7 HEPARANASE 2 authKW 206544 1% 100% 6
8 BRUCE R P ORT MED address 156321 12% 4% 110
9 HUMAN HEPARANASE authKW 137696 0% 100% 4
10 RONEPARSTAT authKW 137696 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 2545 29% 0% 255
2 Biochemistry & Molecular Biology 671 26% 0% 230
3 Cell Biology 604 15% 0% 133
4 Hematology 538 8% 0% 73
5 Medicine, Research & Experimental 163 6% 0% 55
6 Peripheral Vascular Diseases 146 5% 0% 40
7 Immunology 137 8% 0% 69
8 Pathology 94 4% 0% 32
9 Chemistry, Medicinal 37 3% 0% 24
10 Urology & Nephrology 34 3% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC VASC BIOL 2816075 16% 56% 145
2 BRUCE R P ORT MED 156321 12% 4% 110
3 SHARETT 120477 1% 50% 7
4 DRUG DESIGN GRP 109747 1% 25% 13
5 MOL ONCOGENESIS GRP 103272 0% 100% 3
6 CANC VASC BIOL GRP 84482 1% 27% 9
7 THROMBOSIS HEMOSTASIS UNIT 75208 2% 11% 20
8 CANC MOL IMMUNOL GRP 68848 0% 100% 2
9 CANC VASC 68848 0% 100% 2
10 ONCOL AREA DEV 61961 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEOPLASIA 3433 1% 1% 13
2 MATRIX BIOLOGY 1626 1% 1% 8
3 GLYCOBIOLOGY 1195 1% 0% 10
4 PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS 852 0% 1% 3
5 INVASION & METASTASIS 701 0% 1% 3
6 CANCER RESEARCH 698 3% 0% 29
7 ADVANCES IN ENZYME REGULATION 514 0% 1% 3
8 JOURNAL OF CELLULAR PHYSIOLOGY 473 1% 0% 12
9 JOURNAL OF BIOLOGICAL CHEMISTRY 412 5% 0% 46
10 THROMBOSIS RESEARCH 388 1% 0% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HEPARANASE 10355716 43% 79% 380 Search HEPARANASE Search HEPARANASE
2 HEPARANASE INHIBITOR 489582 2% 89% 16 Search HEPARANASE+INHIBITOR Search HEPARANASE+INHIBITOR
3 PI 88 432536 2% 74% 17 Search PI+88 Search PI+88
4 HEPARAN SULFATE 272554 12% 8% 103 Search HEPARAN+SULFATE Search HEPARAN+SULFATE
5 HEPARANASE 1 229486 1% 67% 10 Search HEPARANASE+1 Search HEPARANASE+1
6 HEPARANASE 2 206544 1% 100% 6 Search HEPARANASE+2 Search HEPARANASE+2
7 HUMAN HEPARANASE 137696 0% 100% 4 Search HUMAN+HEPARANASE Search HUMAN+HEPARANASE
8 RONEPARSTAT 137696 0% 100% 4 Search RONEPARSTAT Search RONEPARSTAT
9 MIR 1258 103272 0% 100% 3 Search MIR+1258 Search MIR+1258
10 SST0001 103272 0% 100% 3 Search SST0001 Search SST0001

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RIVARA, S , MILAZZO, FM , GIANNINI, G , (2016) HEPARANASE: A RAINBOW PHARMACOLOGICAL TARGET ASSOCIATED TO MULTIPLE PATHOLOGIES INCLUDING RARE DISEASES.FUTURE MEDICINAL CHEMISTRY. VOL. 8. ISSUE 6. P. 647 -680 150 78% 6
2 SANDERSON, RD , ELKIN, M , RAPRAEGER, AC , ILAN, N , VLODAVSKY, I , (2017) HEPARANASE REGULATION OF CANCER, AUTOPHAGY AND INFLAMMATION: NEW MECHANISMS AND TARGETS FOR THERAPY.FEBS JOURNAL. VOL. 284. ISSUE 1. P. 42 -55 83 59% 3
3 VLODAYSKY, I , SINGH, P , BOYANGO, I , GUTTER-KAPON, L , ELKIN, M , SANDERSON, RD , LIAN, N , (2016) HEPARANASE: FROM BASIC RESEARCH TO THERAPEUTIC APPLICATIONS IN CANCER AND INFLAMMATION.DRUG RESISTANCE UPDATES. VOL. 29. ISSUE . P. 54 -75 147 60% 0
4 ILAN, N , ELKIN, M , VLODAVSKY, I , (2006) REGULATION, FUNCTION AND CLINICAL SIGNIFICANCE OF HEPARANASE IN CANCER METASTASIS AND ANGIOGENESIS.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 38. ISSUE 12. P. 2018 -2039 109 75% 208
5 MASOLA, V , SECCHI, MF , GAMBARO, G , ONISTO, M , (2014) HEPARANASE AS A TARGET IN CANCER THERAPY.CURRENT CANCER DRUG TARGETS. VOL. 14. ISSUE 3. P. 286 -293 90 91% 8
6 MCKENZIE, EA , (2007) HEPARANASE: A TARGET FOR DRUG DISCOVERY IN CANCER AND INFLAMMATION.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 151. ISSUE 1. P. 1-14 93 82% 144
7 VREYS, V , DAVID, G , (2007) MAMMALIAN HEPARANASE: WHAT IS THE MESSAGE?.JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. VOL. 11. ISSUE 3. P. 427 -452 117 67% 117
8 MEIROVITZ, A , GOLDBERG, R , BINDER, A , RUBINSTEIN, AM , HERMANO, E , ELKIN, M , (2013) HEPARANASE IN INFLAMMATION AND INFLAMMATION-ASSOCIATED CANCER.FEBS JOURNAL. VOL. 280. ISSUE 10. P. 2307-2319 96 73% 24
9 MIAO, HQ , LIU, H , NAVARRO, E , KUSSIE, P , ZHU, ZP , (2006) DEVELOPMENT OF HEPARANASE INHIBITORS FOR ANTI-CANCER THERAPY.CURRENT MEDICINAL CHEMISTRY. VOL. 13. ISSUE 18. P. 2101-2111 93 87% 74
10 GOLDBERG, R , MEIROVITZ, A , HIRSHOREN, N , BULVIK, R , BINDER, A , RUBINSTEIN, AM , ELKIN, M , (2013) VERSATILE ROLE OF HEPARANASE IN INFLAMMATION.MATRIX BIOLOGY. VOL. 32. ISSUE 5. P. 234-240 84 67% 23

Classes with closest relation at Level 1


Rank Class id link
1 6202 SYNDECAN 1//SYNDECAN//SYNDECAN 4
2 1305 HEPARAN SULFATE//GLYCOSAMINOGLYCANS//HEPAROSAN
3 11814 SULODEXIDE//HEPARIN//INHALED HEPARIN
4 20445 PERLECAN//SCHWARTZ JAMPEL SYNDROME//STUVE WIEDEMANN SYNDROME
5 27430 LRIG1//LRIG3//UROFACIAL SYNDROME
6 17037 GLYCOCALYX//ENDOTHELIAL GLYCOCALYX//ENDOTHELIAL SURFACE LAYER
7 36560 CALCIUM LOW CONDITION//ANCHORING VILLI//ANEURYSMAL CHANGES PULMONARY ARTERIES
8 30760 ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//HEPARIN DERIVED OLIGOSACCHARIDE//NEUROPATHOL S
9 18710 L IDURONIC ACID//CARDIOVASC THROMBOSE//DARA
10 18138 SURAMIN//HT 29 D4 CELLS//SURAMIN ANALOGS

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