Class information for:
Level 2: YAP//HIPPO PATHWAY//TAZ

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3159 2202 47.8 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
3159 2             YAP//HIPPO PATHWAY//TAZ 2202
5305 1                   YAP//HIPPO PATHWAY//TAZ 1643
23640 1                   PUR ALPHA//SCALLOPED//VESTIGIAL 339
34318 1                   CIZ1//ENHANCER OF RUDIMENTARY//CW DOMAIN 113
34699 1                   BIOLOGICAL FEEDBACK MECHANISMS//BIOMOL STRUCT L14//CHOLESTEROL BIOSYNTHESIS MODEL 107

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 YAP authKW 2009664 10% 65% 222
2 HIPPO PATHWAY authKW 1970079 8% 81% 176
3 TAZ authKW 1068931 5% 73% 105
4 HIPPO authKW 1063543 5% 74% 104
5 HIPPO SIGNALING authKW 585937 2% 78% 54
6 YES ASSOCIATED PROTEIN authKW 536925 2% 79% 49
7 TEAD authKW 350635 1% 82% 31
8 LATS2 authKW 333903 2% 71% 34
9 PUR ALPHA authKW 315861 1% 84% 27
10 LATS1 authKW 244481 1% 77% 23

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 15927 44% 0% 959
2 Developmental Biology 5472 10% 0% 227
3 Biochemistry & Molecular Biology 4384 39% 0% 851
4 Oncology 2739 20% 0% 435
5 Genetics & Heredity 2094 14% 0% 307
6 Biophysics 242 5% 0% 108
7 Cell & Tissue Engineering 65 1% 0% 13
8 Biology 54 2% 0% 47
9 Medicine, Research & Experimental 48 3% 0% 66
10 Pathology 41 2% 0% 43

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL GROWTH PROLIFERAT 227512 1% 86% 19
2 OPTOSIS PROLIFERAT CONTROL 90572 1% 47% 14
3 SIGNAL TRANSDUCT PROTE PROFILING 68254 0% 62% 8
4 CHEM BIOL SCREENING 49910 0% 60% 6
5 CREAT CELL DIFFERENTIAT 49516 0% 71% 5
6 INTER DEGREE PROGRAM CELL DEV BIOL 44367 0% 80% 4
7 TUMOUR SUPP SOR SIGNALLING NETWORKS 44367 0% 80% 4
8 CELL BIOL HLTH DIS 27731 0% 100% 2
9 INTER DEGREE PROGRAM MOL CELLULAR INTE 27731 0% 100% 2
10 MED DENT NUTR 27731 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SCIENCE SIGNALING 6027 1% 2% 26
2 DEVELOPMENTAL CELL 5819 1% 1% 33
3 ONCOTARGET 4979 3% 1% 67
4 GENES & DEVELOPMENT 4399 2% 1% 49
5 GENETICA POLONICA 4055 0% 4% 7
6 NATURE CELL BIOLOGY 2926 1% 1% 24
7 CURRENT BIOLOGY 2315 2% 0% 39
8 PROTEIN & CELL 2268 0% 2% 10
9 CELL REPORTS 2209 1% 1% 23
10 ONCOGENE 1840 2% 0% 50

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 YAP 2009664 10% 65% 222 Search YAP Search YAP
2 HIPPO PATHWAY 1970079 8% 81% 176 Search HIPPO+PATHWAY Search HIPPO+PATHWAY
3 TAZ 1068931 5% 73% 105 Search TAZ Search TAZ
4 HIPPO 1063543 5% 74% 104 Search HIPPO Search HIPPO
5 HIPPO SIGNALING 585937 2% 78% 54 Search HIPPO+SIGNALING Search HIPPO+SIGNALING
6 YES ASSOCIATED PROTEIN 536925 2% 79% 49 Search YES+ASSOCIATED+PROTEIN Search YES+ASSOCIATED+PROTEIN
7 TEAD 350635 1% 82% 31 Search TEAD Search TEAD
8 LATS2 333903 2% 71% 34 Search LATS2 Search LATS2
9 PUR ALPHA 315861 1% 84% 27 Search PUR+ALPHA Search PUR+ALPHA
10 LATS1 244481 1% 77% 23 Search LATS1 Search LATS1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MENG, ZP , MOROISHI, T , GUAN, KL , (2016) MECHANISMS OF HIPPO PATHWAY REGULATION.GENES & DEVELOPMENT. VOL. 30. ISSUE 1. P. 1 -17 168 85% 28
2 JOHNSON, R , HALDER, G , (2014) THE TWO FACES OF HIPPO: TARGETING THE HIPPO PATHWAY FOR REGENERATIVE MEDICINE AND CANCER TREATMENT.NATURE REVIEWS DRUG DISCOVERY. VOL. 13. ISSUE 1. P. 63-79 182 84% 149
3 ZANCONATO, F , CORDENONSI, M , PICCOLO, S , (2016) YAP/TAZ AT THE ROOTS OF CANCER.CANCER CELL. VOL. 29. ISSUE 6. P. 783 -803 182 87% 14
4 PICCOLO, S , DUPONT, S , CORDENONSI, M , (2014) THE BIOLOGY OF YAP/TAZ: HIPPO SIGNALING AND BEYOND.PHYSIOLOGICAL REVIEWS. VOL. 94. ISSUE 4. P. 1287 -1312 201 78% 124
5 YU, FX , ZHAO, B , GUAN, KL , (2015) HIPPO PATHWAY IN ORGAN SIZE CONTROL, TISSUE HOMEOSTASIS, AND CANCER.CELL. VOL. 163. ISSUE 4. P. 811 -828 168 85% 70
6 KODAKA, M , HATA, Y , (2015) THE MAMMALIAN HIPPO PATHWAY: REGULATION AND FUNCTION OF YAP1 AND TAZ.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 72. ISSUE 2. P. 285 -306 203 85% 16
7 PAN, DJ , (2010) THE HIPPO SIGNALING PATHWAY IN DEVELOPMENT AND CANCER.DEVELOPMENTAL CELL. VOL. 19. ISSUE 4. P. 491-505 125 73% 654
8 YU, FX , GUAN, KL , (2013) THE HIPPO PATHWAY: REGULATORS AND REGULATIONS.GENES & DEVELOPMENT. VOL. 27. ISSUE 4. P. 355-371 132 65% 270
9 HANSEN, CG , MOROISHI, T , GUAN, KL , (2015) YAP AND TAZ: A NEXUS FOR HIPPO SIGNALING AND BEYOND.TRENDS IN CELL BIOLOGY. VOL. 25. ISSUE 9. P. 499 -513 138 76% 41
10 ZHU, C , LI, L , ZHAO, B , (2015) THE REGULATION AND FUNCTION OF YAP TRANSCRIPTION CO-ACTIVATOR.ACTA BIOCHIMICA ET BIOPHYSICA SINICA. VOL. 47. ISSUE 1. P. 16 -28 163 89% 6

Classes with closest relation at Level 2


Rank Class id link
1 3713 A20//LAPTM4B//WWP1
2 253 DROSOPHILA//DEVELOPMENTAL BIOLOGY//DEVELOPMENT
3 1425 WNT//BETA CATENIN//FRIZZLED
4 3126 PERIOSTIN//CONNECTIVE TISSUE GROWTH FACTOR//CTGF
5 3108 FOXM1//FOXO1//FOXO
6 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
7 3564 14 3 3 PROTEIN//14 3 3//14 3 3 SIGMA
8 3602 EZRIN//MOESIN//RADIXIN
9 3425 YB 1//COLD SHOCK PROTEIN//Y BOX BINDING PROTEIN 1
10 1195 JNK//ERK5//MAP KINASE

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