Class information for:
Level 1: YAP//HIPPO PATHWAY//TAZ

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5305 1643 51.7 95%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
3159 2             YAP//HIPPO PATHWAY//TAZ 2202
5305 1                   YAP//HIPPO PATHWAY//TAZ 1643

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 YAP authKW 2645248 13% 65% 220
2 HIPPO PATHWAY authKW 2551226 11% 79% 173
3 TAZ authKW 1432686 6% 73% 105
4 HIPPO authKW 1425464 6% 74% 104
5 HIPPO SIGNALING authKW 785328 3% 78% 54
6 YES ASSOCIATED PROTEIN authKW 719637 3% 79% 49
7 LATS2 authKW 447531 2% 71% 34
8 LATS1 authKW 327677 1% 77% 23
9 CELL GROWTH PROLIFERAT address 304932 1% 86% 19
10 YORKIE authKW 292678 1% 75% 21

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 16613 51% 0% 839
2 Developmental Biology 5469 12% 0% 195
3 Oncology 3361 25% 0% 405
4 Biochemistry & Molecular Biology 3036 37% 0% 615
5 Genetics & Heredity 957 11% 0% 185
6 Biophysics 143 5% 0% 74
7 Cell & Tissue Engineering 95 1% 0% 13
8 Pathology 74 3% 0% 43
9 Medicine, Research & Experimental 59 3% 0% 57
10 Gastroenterology & Hepatology 24 2% 0% 33

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL GROWTH PROLIFERAT 304932 1% 86% 19
2 OPTOSIS PROLIFERAT CONTROL 121397 1% 47% 14
3 SIGNAL TRANSDUCT PROTE PROFILING 91481 0% 62% 8
4 CHEM BIOL SCREENING 66895 0% 60% 6
5 CREAT CELL DIFFERENTIAT 66366 0% 71% 5
6 INTER DEGREE PROGRAM CELL DEV BIOL 59465 0% 80% 4
7 TUMOUR SUPP SOR SIGNALLING NETWORKS 59465 0% 80% 4
8 CELL BIOL HLTH DIS 37167 0% 100% 2
9 INTER DEGREE PROGRAM MOL CELLULAR INTE 37167 0% 100% 2
10 MED DENT NUTR 37167 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SCIENCE SIGNALING 8096 2% 2% 26
2 DEVELOPMENTAL CELL 7822 2% 1% 33
3 ONCOTARGET 6719 4% 1% 67
4 GENES & DEVELOPMENT 4772 3% 1% 44
5 NATURE CELL BIOLOGY 3938 1% 1% 24
6 CELL REPORTS 2976 1% 1% 23
7 CURRENT BIOLOGY 2969 2% 0% 38
8 PROTEIN & CELL 2466 1% 1% 9
9 ONCOGENE 2300 3% 0% 48
10 CANCER CELL 2032 1% 1% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 YAP 2645248 13% 65% 220 Search YAP Search YAP
2 HIPPO PATHWAY 2551226 11% 79% 173 Search HIPPO+PATHWAY Search HIPPO+PATHWAY
3 TAZ 1432686 6% 73% 105 Search TAZ Search TAZ
4 HIPPO 1425464 6% 74% 104 Search HIPPO Search HIPPO
5 HIPPO SIGNALING 785328 3% 78% 54 Search HIPPO+SIGNALING Search HIPPO+SIGNALING
6 YES ASSOCIATED PROTEIN 719637 3% 79% 49 Search YES+ASSOCIATED+PROTEIN Search YES+ASSOCIATED+PROTEIN
7 LATS2 447531 2% 71% 34 Search LATS2 Search LATS2
8 LATS1 327677 1% 77% 23 Search LATS1 Search LATS1
9 YORKIE 292678 1% 75% 21 Search YORKIE Search YORKIE
10 MST1 292128 2% 60% 26 Search MST1 Search MST1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MENG, ZP , MOROISHI, T , GUAN, KL , (2016) MECHANISMS OF HIPPO PATHWAY REGULATION.GENES & DEVELOPMENT. VOL. 30. ISSUE 1. P. 1 -17 168 85% 28
2 JOHNSON, R , HALDER, G , (2014) THE TWO FACES OF HIPPO: TARGETING THE HIPPO PATHWAY FOR REGENERATIVE MEDICINE AND CANCER TREATMENT.NATURE REVIEWS DRUG DISCOVERY. VOL. 13. ISSUE 1. P. 63-79 182 84% 149
3 ZANCONATO, F , CORDENONSI, M , PICCOLO, S , (2016) YAP/TAZ AT THE ROOTS OF CANCER.CANCER CELL. VOL. 29. ISSUE 6. P. 783 -803 182 87% 14
4 PICCOLO, S , DUPONT, S , CORDENONSI, M , (2014) THE BIOLOGY OF YAP/TAZ: HIPPO SIGNALING AND BEYOND.PHYSIOLOGICAL REVIEWS. VOL. 94. ISSUE 4. P. 1287 -1312 198 77% 124
5 YU, FX , ZHAO, B , GUAN, KL , (2015) HIPPO PATHWAY IN ORGAN SIZE CONTROL, TISSUE HOMEOSTASIS, AND CANCER.CELL. VOL. 163. ISSUE 4. P. 811 -828 168 85% 70
6 KODAKA, M , HATA, Y , (2015) THE MAMMALIAN HIPPO PATHWAY: REGULATION AND FUNCTION OF YAP1 AND TAZ.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 72. ISSUE 2. P. 285 -306 201 84% 16
7 PAN, DJ , (2010) THE HIPPO SIGNALING PATHWAY IN DEVELOPMENT AND CANCER.DEVELOPMENTAL CELL. VOL. 19. ISSUE 4. P. 491-505 124 72% 654
8 YU, FX , GUAN, KL , (2013) THE HIPPO PATHWAY: REGULATORS AND REGULATIONS.GENES & DEVELOPMENT. VOL. 27. ISSUE 4. P. 355-371 132 65% 270
9 HANSEN, CG , MOROISHI, T , GUAN, KL , (2015) YAP AND TAZ: A NEXUS FOR HIPPO SIGNALING AND BEYOND.TRENDS IN CELL BIOLOGY. VOL. 25. ISSUE 9. P. 499 -513 138 76% 41
10 ZHU, C , LI, L , ZHAO, B , (2015) THE REGULATION AND FUNCTION OF YAP TRANSCRIPTION CO-ACTIVATOR.ACTA BIOCHIMICA ET BIOPHYSICA SINICA. VOL. 47. ISSUE 1. P. 16 -28 163 89% 6

Classes with closest relation at Level 1


Rank Class id link
1 28520 MAP4K4//TNIK//MST3
2 23640 PUR ALPHA//SCALLOPED//VESTIGIAL
3 17318 CELL COMPETITION//COMPENSATORY PROLIFERATION//IMAGINAL DISC
4 22610 WWP1//WW DOMAIN//CKIP 1
5 15424 RASSF1A//RBM5//RASSF2
6 37544 PIGMENTED PARAVENOUS RETINOCHOROIDAL ATROPHY//HELICOID PERIPAPILLARY CHORIORETINAL DEGENERATION//PARAVENOUS
7 31291 IASPP//ASPP2//53BP2
8 29086 KIBRA//PKM ZETA//PROTEIN KINASE M ZETA
9 8463 PLANAR CELL POLARITY//VANGL2//PLANAR POLARITY
10 11431 CRUMBS//SCRIBBLE//ERBIN

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