Class information for:
Level 2: BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2479 3954 34.7 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
59 3       ANESTHESIOLOGY//PAIN//CHRONIC PAIN 88506
2479 2             BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL 3954
5211 1                   BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL 1656
7391 1                   MORPHINE 6 GLUCURONIDE//OXYCODONE//MORPHINE 3 GLUCURONIDE 1372
16064 1                   OPRM1//A118G//OPRM1 GENE 675
30362 1                   COMPLICATIONS NORPETHIDINE TOXICITY//OPIOIDS PETHIDINE//PETHIDINE HYDROCHLORIDE 170
36429 1                   KETOBEMIDONE//BUCCAL ABSORPTION PRODRUG//KAROLINSKA PHARM PEDIAT CANC UNIT 81

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BREAKTHROUGH PAIN authKW 1028651 4% 85% 157
2 CANCER PAIN authKW 626394 8% 25% 322
3 FENTANYL authKW 480353 8% 20% 311
4 OXYCODONE authKW 474292 4% 35% 176
5 MORPHINE 6 GLUCURONIDE authKW 410373 2% 60% 89
6 OPIOID ROTATION authKW 338957 1% 77% 57
7 MORPHINE 3 GLUCURONIDE authKW 289041 2% 59% 63
8 OPRM1 authKW 253194 2% 52% 63
9 PAIN RELIEF PALLIAT CARE UNIT address 252187 2% 41% 79
10 TRANSDERMAL FENTANYL authKW 241909 1% 61% 51

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Anesthesiology 34498 18% 1% 708
2 Pharmacology & Pharmacy 9303 30% 0% 1170
3 Health Care Sciences & Services 9244 11% 0% 423
4 Clinical Neurology 4321 16% 0% 616
5 Medicine, General & Internal 3110 14% 0% 564
6 Neurosciences 1028 12% 0% 466
7 Medicine, Legal 877 2% 0% 67
8 Toxicology 868 5% 0% 205
9 Oncology 656 9% 0% 346
10 Emergency Medicine 311 1% 0% 54

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PAIN RELIEF PALLIAT CARE UNIT 252187 2% 41% 79
2 ANESTHESIA INTENS CARE UNIT 64801 1% 19% 45
3 PAIN MED PALLIAT CARE 29203 1% 15% 25
4 PALLIAT MED 28959 2% 5% 73
5 ANAESTHESIOL EMERGENCY MED 28491 0% 31% 12
6 MOL EPIDEMIOL PAIN PROGRAM 27790 0% 60% 6
7 PAIN RELIEF PALLIAT CARE 27016 0% 50% 7
8 HOME PALLIAT CARE PROGRAM 25263 0% 55% 6
9 ANESTHESIA INTENS CARE PAIN RELIEF PALLIAT 24124 0% 63% 5
10 LOTUS CLIN LLC 23162 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PAIN AND SYMPTOM MANAGEMENT 88514 5% 6% 196
2 PAIN 22932 4% 2% 153
3 PALLIATIVE MEDICINE 18394 2% 4% 61
4 ADVANCES IN PAIN RESEARCH AND THERAPY 14970 1% 6% 35
5 JOURNAL OF ANALYTICAL TOXICOLOGY 13630 2% 2% 77
6 EUROPEAN JOURNAL OF PAIN 10877 1% 3% 54
7 SUPPORTIVE CARE IN CANCER 7758 2% 2% 66
8 PAIN MEDICINE 6579 1% 2% 41
9 MEDICINA PALIATIVA 6020 0% 7% 12
10 CLINICAL DRUG INVESTIGATION 5876 1% 2% 41

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BREAKTHROUGH PAIN 1028651 4% 85% 157 Search BREAKTHROUGH+PAIN Search BREAKTHROUGH+PAIN
2 CANCER PAIN 626394 8% 25% 322 Search CANCER+PAIN Search CANCER+PAIN
3 FENTANYL 480353 8% 20% 311 Search FENTANYL Search FENTANYL
4 OXYCODONE 474292 4% 35% 176 Search OXYCODONE Search OXYCODONE
5 MORPHINE 6 GLUCURONIDE 410373 2% 60% 89 Search MORPHINE+6+GLUCURONIDE Search MORPHINE+6+GLUCURONIDE
6 OPIOID ROTATION 338957 1% 77% 57 Search OPIOID+ROTATION Search OPIOID+ROTATION
7 MORPHINE 3 GLUCURONIDE 289041 2% 59% 63 Search MORPHINE+3+GLUCURONIDE Search MORPHINE+3+GLUCURONIDE
8 OPRM1 253194 2% 52% 63 Search OPRM1 Search OPRM1
9 TRANSDERMAL FENTANYL 241909 1% 61% 51 Search TRANSDERMAL+FENTANYL Search TRANSDERMAL+FENTANYL
10 BREAKTHROUGH CANCER PAIN 196756 1% 88% 29 Search BREAKTHROUGH+CANCER+PAIN Search BREAKTHROUGH+CANCER+PAIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ANDERSEN, G , CHRISTRUP, L , SJOGREN, P , (2003) RELATIONSHIPS AMONG MORPHINE METABOLISM, PAIN AND SIDE EFFECTS DURING LONG-TERM TREATMENT: AN UPDATE.JOURNAL OF PAIN AND SYMPTOM MANAGEMENT. VOL. 25. ISSUE 1. P. 74-91 100 88% 52
2 KING, S , FORBES, K , HANKS, GW , FERRO, CJ , CHAMBERS, EJ , (2011) A SYSTEMATIC REVIEW OF THE USE OF OPIOID MEDICATION FOR THOSE WITH MODERATE TO SEVERE CANCER PAIN AND RENAL IMPAIRMENT: A EUROPEAN PALLIATIVE CARE RESEARCH COLLABORATIVE OPIOID GUIDELINES PROJECT.PALLIATIVE MEDICINE. VOL. 25. ISSUE 5. P. 525 -552 95 67% 45
3 KILPATRICK, GJ , SMITH, TW , (2005) MORPHINE-6-GLUCURONIDE: ACTIONS AND MECHANISMS.MEDICINAL RESEARCH REVIEWS. VOL. 25. ISSUE 5. P. 521-544 110 68% 74
4 GRAPE, S , SCHUG, SA , LAUER, S , SCHUG, BS , (2010) FORMULATIONS OF FENTANYL FOR THE MANAGEMENT OF PAIN.DRUGS. VOL. 70. ISSUE 1. P. 57-72 73 88% 43
5 MERCADANTE, S , PORTENOY, RK , (2016) BREAKTHROUGH CANCER PAIN: TWENTY-FIVE YEARS OF STUDY.PAIN. VOL. 157. ISSUE 12. P. 2657 -2663 57 100% 1
6 DAVIS, MP , (2011) FENTANYL FOR BREAKTHROUGH PAIN: A SYSTEMATIC REVIEW.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 11. ISSUE 8. P. 1197 -1216 71 83% 27
7 SMITH, H , (2012) A COMPREHENSIVE REVIEW OF RAPID-ONSET OPIOIDS FOR BREAKTHROUGH PAIN.CNS DRUGS. VOL. 26. ISSUE 6. P. 509-535 59 91% 23
8 KLIMAS, R , MIKUS, G , (2014) MORPHINE-6-GLUCURONIDE IS RESPONSIBLE FOR THE ANALGESIC EFFECT AFTER MORPHINE ADMINISTRATION: A QUANTITATIVE REVIEW OF MORPHINE, MORPHINE-6-GLUCURONIDE, AND MORPHINE-3-GLUCURONIDE.BRITISH JOURNAL OF ANAESTHESIA. VOL. 113. ISSUE 6. P. 935 -944 58 85% 12
9 WIFFEN, PJ , WEE, B , MOORE, RA , (2016) ORAL MORPHINE FOR CANCER PAIN.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 4. P. - 80 65% 0
10 LEPPERT, W , (2009) THE ROLE OF METHADONE IN CANCER PAIN TREATMENT - A REVIEW.INTERNATIONAL JOURNAL OF CLINICAL PRACTICE. VOL. 63. ISSUE 7. P. 1095 -1109 77 74% 26

Classes with closest relation at Level 2


Rank Class id link
1 214 FIBROMYALGIA//CHRONIC PAIN//PAIN
2 1436 BUPRENORPHINE//METHADONE//SUBSTANCE ABUSE
3 2583 SPINAL CORD STIMULATION//NEUROMODULATION//GLOMUS TUMOR
4 2563 TRAMADOL//DIPYRONE//TAPENTADOL
5 141 ANESTHESIOLOGY//BUPIVACAINE//REGIONAL ANESTHESIA AND PAIN MEDICINE
6 592 MDMA//ECSTASY//JOURNAL OF ANALYTICAL TOXICOLOGY
7 1912 SEDATION//KETAMINE//MIDAZOLAM
8 121 OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR
9 4136 FENCAMFAMINE//DEZOCINE//MAZAPERTINE
10 1858 VETERINARY ANAESTHESIA AND ANALGESIA//MEDETOMIDINE//XYLAZINE

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