Class information for:
Level 1: MORPHINE 6 GLUCURONIDE//OXYCODONE//MORPHINE 3 GLUCURONIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7391 1372 32.9 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
59 3       ANESTHESIOLOGY//PAIN//CHRONIC PAIN 88506
2479 2             BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL 3954
7391 1                   MORPHINE 6 GLUCURONIDE//OXYCODONE//MORPHINE 3 GLUCURONIDE 1372

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MORPHINE 6 GLUCURONIDE authKW 1130423 6% 58% 87
2 OXYCODONE authKW 1046981 11% 31% 154
3 MORPHINE 3 GLUCURONIDE authKW 833230 5% 59% 63
4 HYDROMORPHONE authKW 374156 4% 29% 59
5 OXYMORPHONE authKW 245705 2% 39% 28
6 MORPHINE authKW 209905 19% 4% 260
7 NOROXYCODONE authKW 202311 1% 91% 10
8 MORPHINE METABOLITES authKW 188041 1% 65% 13
9 MORPHINE 6 GLUCURONIDE M6G authKW 155781 1% 100% 7
10 CONTROLLED RELEASE MORPHINE authKW 133527 0% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Anesthesiology 11805 18% 0% 244
2 Pharmacology & Pharmacy 7960 45% 0% 614
3 Health Care Sciences & Services 1617 8% 0% 106
4 Medicine, General & Internal 733 12% 0% 166
5 Clinical Neurology 715 11% 0% 155
6 Toxicology 564 7% 0% 93
7 Neurosciences 177 9% 0% 126
8 Medicine, Legal 175 1% 0% 18
9 Chemistry, Medicinal 172 4% 0% 56
10 Medicine, Research & Experimental 81 4% 0% 56

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LOTUS CLIN LLC 66763 0% 100% 3
2 CHRON PAIN DAY PROGRAM 50071 0% 75% 3
3 PROGRAM CENTURY 21SURUGA KU 44509 0% 100% 2
4 GREY NUNS COMMUNITY HOSP HLTH 33379 0% 50% 3
5 STOCKHOLMS SJUKHEM FDN 33379 0% 50% 3
6 ANESTHESIOL INTENS CARE EMERGENCY CARE PAI 22880 0% 17% 6
7 ABT ALLGEMEINE INNERE MED ALTERSMED 22254 0% 100% 1
8 ABT PALLIAT MED MERZTHER IE 22254 0% 100% 1
9 ACUTE PAIN CARE SERV 22254 0% 100% 1
10 AFFILIATED CANE HOSP 22254 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN PAIN RESEARCH AND THERAPY 25741 2% 4% 27
2 JOURNAL OF PAIN AND SYMPTOM MANAGEMENT 20066 4% 2% 55
3 JOURNAL OF ANALYTICAL TOXICOLOGY 6377 2% 1% 31
4 PHARMACOLOGY & TOXICOLOGY 4960 2% 1% 23
5 PAIN 4727 3% 1% 41
6 CLINICAL ONCOLOGY MONOGRAPHS 4082 0% 6% 3
7 CLINICAL PHARMACOLOGY & THERAPEUTICS 3866 2% 1% 32
8 PALLIATIVE MEDICINE 3639 1% 1% 16
9 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 3310 3% 0% 35
10 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2979 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MORPHINE 6 GLUCURONIDE 1130423 6% 58% 87 Search MORPHINE+6+GLUCURONIDE Search MORPHINE+6+GLUCURONIDE
2 OXYCODONE 1046981 11% 31% 154 Search OXYCODONE Search OXYCODONE
3 MORPHINE 3 GLUCURONIDE 833230 5% 59% 63 Search MORPHINE+3+GLUCURONIDE Search MORPHINE+3+GLUCURONIDE
4 HYDROMORPHONE 374156 4% 29% 59 Search HYDROMORPHONE Search HYDROMORPHONE
5 OXYMORPHONE 245705 2% 39% 28 Search OXYMORPHONE Search OXYMORPHONE
6 MORPHINE 209905 19% 4% 260 Search MORPHINE Search MORPHINE
7 NOROXYCODONE 202311 1% 91% 10 Search NOROXYCODONE Search NOROXYCODONE
8 MORPHINE METABOLITES 188041 1% 65% 13 Search MORPHINE+METABOLITES Search MORPHINE+METABOLITES
9 MORPHINE 6 GLUCURONIDE M6G 155781 1% 100% 7 Search MORPHINE+6+GLUCURONIDE+M6G Search MORPHINE+6+GLUCURONIDE+M6G
10 CONTROLLED RELEASE MORPHINE 133527 0% 100% 6 Search CONTROLLED+RELEASE+MORPHINE Search CONTROLLED+RELEASE+MORPHINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ANDERSEN, G , CHRISTRUP, L , SJOGREN, P , (2003) RELATIONSHIPS AMONG MORPHINE METABOLISM, PAIN AND SIDE EFFECTS DURING LONG-TERM TREATMENT: AN UPDATE.JOURNAL OF PAIN AND SYMPTOM MANAGEMENT. VOL. 25. ISSUE 1. P. 74-91 99 88% 52
2 KILPATRICK, GJ , SMITH, TW , (2005) MORPHINE-6-GLUCURONIDE: ACTIONS AND MECHANISMS.MEDICINAL RESEARCH REVIEWS. VOL. 25. ISSUE 5. P. 521-544 99 61% 74
3 KLIMAS, R , MIKUS, G , (2014) MORPHINE-6-GLUCURONIDE IS RESPONSIBLE FOR THE ANALGESIC EFFECT AFTER MORPHINE ADMINISTRATION: A QUANTITATIVE REVIEW OF MORPHINE, MORPHINE-6-GLUCURONIDE, AND MORPHINE-3-GLUCURONIDE.BRITISH JOURNAL OF ANAESTHESIA. VOL. 113. ISSUE 6. P. 935 -944 56 82% 12
4 KING, S , FORBES, K , HANKS, GW , FERRO, CJ , CHAMBERS, EJ , (2011) A SYSTEMATIC REVIEW OF THE USE OF OPIOID MEDICATION FOR THOSE WITH MODERATE TO SEVERE CANCER PAIN AND RENAL IMPAIRMENT: A EUROPEAN PALLIATIVE CARE RESEARCH COLLABORATIVE OPIOID GUIDELINES PROJECT.PALLIATIVE MEDICINE. VOL. 25. ISSUE 5. P. 525 -552 79 56% 45
5 LOTSCH, J , GEISSLINGER, G , (2001) MORPHINE-6-GLUCURONIDE - AN ANALGESIC OF THE FUTURE?.CLINICAL PHARMACOKINETICS. VOL. 40. ISSUE 7. P. 485-499 83 74% 63
6 KLIMAS, R , WITTICKE, D , EL FALLAH, S , MIKUS, G , (2013) CONTRIBUTION OF OXYCODONE AND ITS METABOLITES TO THE OVERALL ANALGESIC EFFECT AFTER OXYCODONE ADMINISTRATION.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 9. ISSUE 5. P. 517-528 45 87% 12
7 MILNE, RW , NATION, RL , SOMOGYI, AA , (1996) THE DISPOSITION OF MORPHINE AND ITS 3- AND 6-GLUCURONIDE METABOLITES IN HUMANS AND ANIMALS, AND THE IMPORTANCE OF THE METABOLITES TO THE PHARMACOLOGICAL EFFECTS OF MORPHINE.DRUG METABOLISM REVIEWS. VOL. 28. ISSUE 3. P. 345-472 129 43% 133
8 LEPPERT, W , (2010) ROLE OF OXYCODONE AND OXYCODONE/NALOXONE IN CANCER PAIN MANAGEMENT.PHARMACOLOGICAL REPORTS. VOL. 62. ISSUE 4. P. 578 -591 55 69% 16
9 OLKKOLA, KT , KONTINEN, VK , SAARI, TI , KALSO, EA , (2013) DOES THE PHARMACOLOGY OF OXYCODONE JUSTIFY ITS INCREASING USE AS AN ANALGESIC?.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 34. ISSUE 4. P. 206-214 51 66% 12
10 SMITH, MT , SOUTH, SM , (2001) THE ROLE OF MORPHINE-6-GLUCURONIDE (M6G) IN PAIN CONTROL.PAIN REVIEWS. VOL. 8. ISSUE 3-4. P. 171 -191 74 68% 1

Classes with closest relation at Level 1


Rank Class id link
1 12018 CODEINE//MORPHINE GLUCURONIDES//6 ACETYLMORPHINE
2 5211 BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL
3 36429 KETOBEMIDONE//BUCCAL ABSORPTION PRODRUG//KAROLINSKA PHARM PEDIAT CANC UNIT
4 30362 COMPLICATIONS NORPETHIDINE TOXICITY//OPIOIDS PETHIDINE//PETHIDINE HYDROCHLORIDE
5 16064 OPRM1//A118G//OPRM1 GENE
6 10049 PATIENT CONTROLLED ANALGESIA//ACUTE PAIN SERVICE//ANALGESIA PATIENT CONTROLLED
7 36873 STRAUB TAIL REACTION//BEIGE J MICE//MU2 OPIOID RECEPTOR
8 30937 INNER BLOOD RETINAL BARRIER//PROTON COUPLED ORGANIC CATION ANTIPORTER//RETINAL CAPILLARY ENDOTHELIAL CELLS
9 28889 DRIVING ABILITY//CANC PAIN UNIT//COGNITIVE FUNCTION PSYCHOMOTOR PERFORMANCE OPIOIDS CANCER PAIN
10 1265 OPIOIDS//CHRONIC NONCANCER PAIN//PRESCRIPTION OPIOIDS

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