Class information for:
Level 2: GSTM1//GSTT1//GLUTATHIONE S TRANSFERASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1741 6518 38.0 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
1741 2             GSTM1//GSTT1//GLUTATHIONE S TRANSFERASE 6518
968 1                   GLUTATHIONE TRANSFERASE//GLUTATHIONE S TRANSFERASE//GLUTATHIONE S TRANSFERASE PI 2930
1419 1                   GSTM1//GSTT1//GSTP1 2673
22578 1                   MICROSOMAL GLUTATHIONE TRANSFERASE//MGST1//MOL GENET PHARMACOL 376
29134 1                   CLIC1//CHLORIDE INTRACELLULAR CHANNEL 1//CLIC4 192
29439 1                   ALPHA GLUTATHIONE S TRANSFERASE//ENZYMES GLUTATHIONE S TRANSFERASE//ALPHA GLUTATHIONE TRANSFERASES 186
30934 1                   GLUTATHIONE S TRANSFERASE OMEGA//GSTO1//GLUTATHIONE S TRANSFERASE OMEGA 1 161

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GSTM1 authKW 1191091 6% 65% 392
2 GSTT1 authKW 1043506 5% 69% 324
3 GLUTATHIONE S TRANSFERASE authKW 1031325 13% 25% 875
4 GLUTATHIONE TRANSFERASE authKW 590764 4% 44% 284
5 GSTP1 authKW 398847 3% 47% 183
6 CYP1A1 authKW 244822 3% 24% 215
7 GLUTATHIONE S TRANSFERASE M1 authKW 146113 1% 59% 53
8 GLUTATHIONE S TRANSFERASE T1 authKW 119685 1% 61% 42
9 GLUTATHIONE S TRANSFERASE PI authKW 113815 1% 40% 61
10 MICROSOMAL GLUTATHIONE TRANSFERASE authKW 79853 0% 95% 18

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 13154 25% 0% 1597
2 Biochemistry & Molecular Biology 10104 35% 0% 2265
3 Toxicology 4496 9% 0% 556
4 Biophysics 2318 8% 0% 511
5 Pharmacology & Pharmacy 1696 12% 0% 772
6 Genetics & Heredity 1079 7% 0% 440
7 Medical Laboratory Technology 358 1% 0% 97
8 Public, Environmental & Occupational Health 328 4% 0% 283
9 Medicine, Research & Experimental 190 3% 0% 212
10 Gastroenterology & Hepatology 165 2% 0% 154

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IAN POTTER FDN PROT CRYSTALLOG 54123 0% 68% 17
2 PROT STRUCT FUNCT UNIT 29727 0% 35% 18
3 PROT STRUCT FUNCT PROGRAMME 28085 0% 50% 12
4 MOL GENET PHARMACOL 21070 0% 75% 6
5 NAST NANOSCI NANOTECHNOL INNOVAT RUME 19116 0% 58% 7
6 PROT STRUCT FUNCT PROGRAM 18727 0% 67% 6
7 MOL GENET GRP 18479 1% 12% 34
8 BIOTA STRUCT BIOL 18154 0% 19% 20
9 BIOCHEM ORGAN CHEM 17643 1% 10% 37
10 IRCCS BAMBIN GESU 14984 0% 80% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOGENETICS 38215 1% 9% 88
2 BIOCHEMICAL JOURNAL 12570 4% 1% 284
3 CHEMICO-BIOLOGICAL INTERACTIONS 11160 2% 2% 117
4 CARCINOGENESIS 11147 3% 1% 168
5 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 10354 2% 2% 119
6 ASIAN PACIFIC JOURNAL OF CANCER PREVENTION 6917 1% 2% 92
7 TUMOR BIOLOGY 6025 1% 1% 90
8 BIOCHEMICAL PHARMACOLOGY 3880 2% 1% 127
9 MOLECULAR BIOLOGY REPORTS 3575 1% 1% 68
10 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 3270 2% 1% 112

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GSTM1 1191091 6% 65% 392 Search GSTM1 Search GSTM1
2 GSTT1 1043506 5% 69% 324 Search GSTT1 Search GSTT1
3 GLUTATHIONE S TRANSFERASE 1031325 13% 25% 875 Search GLUTATHIONE+S+TRANSFERASE Search GLUTATHIONE+S+TRANSFERASE
4 GLUTATHIONE TRANSFERASE 590764 4% 44% 284 Search GLUTATHIONE+TRANSFERASE Search GLUTATHIONE+TRANSFERASE
5 GSTP1 398847 3% 47% 183 Search GSTP1 Search GSTP1
6 CYP1A1 244822 3% 24% 215 Search CYP1A1 Search CYP1A1
7 GLUTATHIONE S TRANSFERASE M1 146113 1% 59% 53 Search GLUTATHIONE+S+TRANSFERASE+M1 Search GLUTATHIONE+S+TRANSFERASE+M1
8 GLUTATHIONE S TRANSFERASE T1 119685 1% 61% 42 Search GLUTATHIONE+S+TRANSFERASE+T1 Search GLUTATHIONE+S+TRANSFERASE+T1
9 GLUTATHIONE S TRANSFERASE PI 113815 1% 40% 61 Search GLUTATHIONE+S+TRANSFERASE+PI Search GLUTATHIONE+S+TRANSFERASE+PI
10 MICROSOMAL GLUTATHIONE TRANSFERASE 79853 0% 95% 18 Search MICROSOMAL+GLUTATHIONE+TRANSFERASE Search MICROSOMAL+GLUTATHIONE+TRANSFERASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HAYES, JD , PULFORD, DJ , (1995) THE GLUTATHIONE S-TRANSFERASE SUPERGENE FAMILY: REGULATION OF GST AND THE CONTRIBUTION OF THE ISOENZYMES TO CANCER CHEMOPROTECTION AND DRUG RESISTANCE.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 30. ISSUE 6. P. 445-600 377 57% 2538
2 MENON, D , BOARD, PG , (2013) GLUTATHIONE TRANSFERASES, REGULATORS OF CELLULAR METABOLISM AND PHYSIOLOGY.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1830. ISSUE 5. P. 3267 -3288 211 64% 75
3 HE, XF , WEI, W , LIU, ZZ , SHEN, XL , YANG, XB , WANG, SL , XIE, DL , (2014) ASSOCIATION BETWEEN THE CYP1A1 T3801C POLYMORPHISM AND RISK OF CANCER: EVIDENCE FROM 268 CASE-CONTROL STUDIES.GENE. VOL. 534. ISSUE 2. P. 324 -344 198 76% 11
4 TSUCHIDA, S , SATO, K , (1992) GLUTATHIONE TRANSFERASES AND CANCER.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 27. ISSUE 4-5. P. 337-384 261 67% 496
5 BECKETT, GJ , HAYES, JD , (1993) GLUTATHIONE S-TRANSFERASES - BIOMEDICAL APPLICATIONS.ADVANCES IN CLINICAL CHEMISTRY, VOL 30. VOL. 30. ISSUE . P. 281-380 210 74% 215
6 DI PIETRO, G , MAGNO, LAV , RIOS-SANTOS, F , (2010) GLUTATHIONE S-TRANSFERASES: AN OVERVIEW IN CANCER RESEARCH.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 6. ISSUE 2. P. 153 -170 106 90% 81
7 MANNERVIK, B , DANIELSON, UH , (1988) GLUTATHIONE TRANSFERASES - STRUCTURE AND CATALYTIC ACTIVITY.CRC CRITICAL REVIEWS IN BIOCHEMISTRY. VOL. 23. ISSUE 3. P. 283-337 116 79% 1505
8 CARLSTEN, C , SAGOO, GS , FRODSHAM, AJ , BURKE, W , HIGGINS, JPT , (2008) GLUTATHIONE S-TRANSFERASE M1 (GSTM1) POLYMORPHISMS AND LUNG CANCER: A LITERATURE-BASED SYSTEMATIC HUGE REVIEW AND META-ANALYSIS.AMERICAN JOURNAL OF EPIDEMIOLOGY. VOL. 167. ISSUE 7. P. 759 -774 122 73% 97
9 BAG, A , JYALA, NS , BAG, N , (2015) CYTOCHROME P450 1A1 GENETIC POLYMORPHISMS AS CANCER BIOMARKERS.INDIAN JOURNAL OF CANCER. VOL. 52. ISSUE 4. P. 479 -+ 107 82% 0
10 ZHANG, Y , NI, YY , ZHANG, H , PAN, YC , MA, JQ , WANG, L , (2012) ASSOCIATION BETWEEN GSTM1 AND GSTT1 ALLELIC VARIANTS AND HEAD AND NECK SQUAMOUS CELL CANCINOMA.PLOS ONE. VOL. 7. ISSUE 10. P. - 56 90% 223

Classes with closest relation at Level 2


Rank Class id link
1 1239 HETEROCYCLIC AMINES//HETEROCYCLIC AROMATIC AMINES//PHIP
2 3196 MNSOD//MANGANESE SUPEROXIDE DISMUTASE//SOD2
3 3033 CARCINOGENESIS//HEPATOCARCINOGENESIS//MEDIUM TERM BIOASSAY
4 3141 EPOXIDE HYDROLASE//HALOALKANE DEHALOGENASE//DEHALOGENASE
5 2994 NRF2//KEAP1//ANTIOXIDANT RESPONSE ELEMENT
6 1422 XRCC1//GEMCITABINE//ERCC1
7 870 PEROXIREDOXIN//THIOREDOXIN//GLUTATHIONE
8 415 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR
9 1407 2 METHOXYESTRADIOL//STEROID SULFATASE//17 BETA HYDROXYSTEROID DEHYDROGENASE
10 573 TOXICOLOGY//BENZENE//TRICHLOROETHYLENE

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