Class information for:
Level 2: SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1124 9675 46.2 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
429 3       SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS 27734
1124 2             SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS 9675
381 1                   CERAMIDE//SPHINGOLIPIDS//SPHINGOMYELINASE 3557
431 1                   SPHINGOSINE 1 PHOSPHATE//FTY720//SPHINGOSINE KINASE 3453
10439 1                   CEREBROSIDE//JASPINE B//PHYTOSPHINGOSINE 1064
11464 1                   LONG CHAIN BASE//SPHINGOLIPIDS//AUREOBASIDIN A 980
22171 1                   MESOTHERAPY//INJECTION LIPOLYSIS//LIPODISSOLVE 391
27422 1                   ALKALINE SPHINGOMYELINASE//BIOMED B11//4 8 SPHINGADIENINE 230

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 SPHINGOSINE 1 PHOSPHATE authKW 2154553 10% 73% 937
2 CERAMIDE authKW 2023835 14% 46% 1387
3 SPHINGOLIPIDS authKW 1586769 10% 52% 965
4 SPHINGOSINE KINASE authKW 848859 3% 85% 316
5 FTY720 authKW 846706 3% 80% 337
6 SPHINGOSINE authKW 505134 3% 50% 321
7 FINGOLIMOD authKW 362155 2% 55% 207
8 SPHINGOMYELINASE authKW 323107 2% 45% 230
9 SPHINGOMYELIN authKW 251994 3% 29% 276
10 SPHINGOSINE KINASE 1 authKW 250289 1% 79% 100

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 19624 39% 0% 3769
2 Cell Biology 8928 17% 0% 1651
3 Biophysics 3845 8% 0% 795
4 Chemistry, Medicinal 2936 6% 0% 569
5 Chemistry, Organic 1958 8% 0% 776
6 Pharmacology & Pharmacy 1248 9% 0% 893
7 Immunology 760 6% 0% 595
8 Oncology 608 6% 0% 611
9 Nutrition & Dietetics 578 3% 0% 259
10 Transplantation 390 2% 0% 167

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOMEMBRANE BIOFUNCT CHEM 196634 1% 64% 98
2 STONY BROOK CANC 57910 0% 61% 30
3 UNIT BIOACT MOL RUBAM 31522 0% 50% 20
4 CELLULAR MOL REGULAT 29958 0% 20% 47
5 U466 27019 0% 28% 31
6 INSERMU466 26281 0% 83% 10
7 UNIT BIOACT MOL 24452 0% 48% 16
8 GENET DEV DIS BRANCH 23342 1% 14% 52
9 RALPH H JOHNSON VET ADM HOSP 23223 0% 82% 9
10 CELLULAR GLYCOBIOL 22878 0% 48% 15

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 38264 2% 7% 181
2 JOURNAL OF LIPID RESEARCH 12664 2% 2% 187
3 JOURNAL OF BIOLOGICAL CHEMISTRY 10736 8% 1% 750
4 ADVANCES IN LIPID RESEARCH 6845 0% 16% 14
5 CELLULAR SIGNALLING 3627 1% 2% 72
6 LIPIDS 3543 1% 1% 83
7 FASEB JOURNAL 3335 1% 1% 103
8 CHEMISTRY AND PHYSICS OF LIPIDS 2350 1% 2% 50
9 PROSTAGLANDINS & OTHER LIPID MEDIATORS 2075 0% 2% 35
10 PROGRESS IN LIPID RESEARCH 1920 0% 3% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 SPHINGOSINE 1 PHOSPHATE 2154553 10% 73% 937 Search SPHINGOSINE+1+PHOSPHATE Search SPHINGOSINE+1+PHOSPHATE
2 CERAMIDE 2023835 14% 46% 1387 Search CERAMIDE Search CERAMIDE
3 SPHINGOLIPIDS 1586769 10% 52% 965 Search SPHINGOLIPIDS Search SPHINGOLIPIDS
4 SPHINGOSINE KINASE 848859 3% 85% 316 Search SPHINGOSINE+KINASE Search SPHINGOSINE+KINASE
5 FTY720 846706 3% 80% 337 Search FTY720 Search FTY720
6 SPHINGOSINE 505134 3% 50% 321 Search SPHINGOSINE Search SPHINGOSINE
7 FINGOLIMOD 362155 2% 55% 207 Search FINGOLIMOD Search FINGOLIMOD
8 SPHINGOMYELINASE 323107 2% 45% 230 Search SPHINGOMYELINASE Search SPHINGOMYELINASE
9 SPHINGOMYELIN 251994 3% 29% 276 Search SPHINGOMYELIN Search SPHINGOMYELIN
10 SPHINGOSINE KINASE 1 250289 1% 79% 100 Search SPHINGOSINE+KINASE+1 Search SPHINGOSINE+KINASE+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VOGT, D , STARK, H , (2017) THERAPEUTIC STRATEGIES AND PHARMACOLOGICAL TOOLS INFLUENCING S1P SIGNALING AND METABOLISM.MEDICINAL RESEARCH REVIEWS. VOL. 37. ISSUE 1. P. 3 -51 396 92% 0
2 ALSHAKER, H , SAUER, L , MONTEIL, D , OTTAVIANI, S , SRIVATS, S , BOHLER, T , PCHEJETSKI, D , (2013) THERAPEUTIC POTENTIAL OF TARGETING SK1 IN HUMAN CANCERS.ROLE OF SPHINGOLIPIDS IN CANCER DEVELOPMENT AND THERAPY. VOL. 117. ISSUE . P. 143-200 284 92% 18
3 TAKABE, K , PAUGH, SW , MILSTIEN, S , SPIEGEL, S , (2008) "INSIDE-OUT" SIGNALING OF SPHINGOSINE-1-PHOSPHATE: THERAPEUTIC TARGETS.PHARMACOLOGICAL REVIEWS. VOL. 60. ISSUE 2. P. 181-195 182 96% 300
4 SCHUCHARDT, M , TOLLE, M , PRUFER, J , VAN DER GIET, M , (2011) PHARMACOLOGICAL RELEVANCE AND POTENTIAL OF SPHINGOSINE 1-PHOSPHATE IN THE VASCULAR SYSTEM.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 163. ISSUE 6. P. 1140 -1162 235 86% 27
5 BIGAUD, M , GUERINI, D , BILLICH, A , BASSILANA, F , BRINKMANN, V , (2014) SECOND GENERATION S1P PATHWAY MODULATORS: RESEARCH STRATEGIES AND CLINICAL DEVELOPMENTS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1841. ISSUE 5. P. 745-758 163 94% 39
6 WHITE, C , ALSHAKER, H , COOPER, C , WINKLER, M , PCHEJETSKI, D , (2016) THE EMERGING ROLE OF FTY720 (FINGOLIMOD) IN CANCER TREATMENT.ONCOTARGET. VOL. 7. ISSUE 17. P. 23106 -23127 199 84% 2
7 PYNE, NJ , PYNE, S , (2010) SPHINGOSINE 1-PHOSPHATE AND CANCER.NATURE REVIEWS CANCER. VOL. 10. ISSUE 7. P. 489 -503 155 82% 305
8 HANNUN, YA , OBEID, LM , (2008) PRINCIPLES OF BIOACTIVE LIPID SIGNALLING: LESSONS FROM SPHINGOLIPIDS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 9. ISSUE 2. P. 139-150 95 84% 1190
9 MARFE, G , MIRONE, G , SHUKLA, A , DI STEFANO, C , (2015) SPHINGOSINE KINASES SIGNALLING IN CARCINOGENESIS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 4. P. 300 -314 178 93% 5
10 ADAN-GOKBULUT, A , KARTAL-YANDIM, M , ISKENDER, G , BARAN, Y , (2013) NOVEL AGENTS TARGETING BIOACTIVE SPHINGOLIPIDS FOR THE TREATMENT OF CANCER.CURRENT MEDICINAL CHEMISTRY. VOL. 20. ISSUE 1. P. 108-122 182 90% 22

Classes with closest relation at Level 2


Rank Class id link
1 2742 LYSOPHOSPHATIDIC ACID//AUTOTAXIN//DIADENOSINE POLYPHOSPHATES
2 1273 GANGLIOSIDES//SIALIC ACID//GLYCOSPHINGOLIPIDS
3 2254 PHOSPHOLIPASE D//DIACYLGLYCEROL KINASE//PHOSPHATIDIC ACID
4 1114 PHOSPHOLIPASE A2//PLASMALOGEN//LIPIDOMICS
5 4152 COOPERAT LIFE SCI//FRONTIER GENOM DRUG DISCOVERY//GLYCOGLYCEROLIPIDS
6 491 GAUCHER DISEASE//LYSOSOMAL STORAGE DISEASE//MUCOPOLYSACCHARIDOSIS
7 1628 LIPID DROPLETS//CARDIOLIPIN//PERILIPIN
8 2735 STEROL CARRIER PROTEIN 2//PHOSPHATIDYLINOSITOL TRANSFER PROTEIN//GLYCOLIPID TRANSFER PROTEIN
9 2709 CAVEOLIN 1//CAVEOLAE//CAVEOLIN
10 1486 PROTEIN KINASE C//BRYOSTATIN//BRYOSTATIN 1

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