Class information for:
Level 1: SPHINGOSINE 1 PHOSPHATE//FTY720//SPHINGOSINE KINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
431 3453 46.4 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
429 3       SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS 27734
1124 2             SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS 9675
431 1                   SPHINGOSINE 1 PHOSPHATE//FTY720//SPHINGOSINE KINASE 3453

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SPHINGOSINE 1 PHOSPHATE authKW 4877354 24% 66% 842
2 FTY720 authKW 2331531 10% 79% 334
3 SPHINGOSINE KINASE authKW 2004054 8% 78% 290
4 FINGOLIMOD authKW 995940 6% 55% 205
5 SPHINGOSINE KINASE 1 authKW 660174 3% 77% 97
6 SPHINGOSINE 1 PHOSPHATE RECEPTOR authKW 495189 2% 81% 69
7 S1P authKW 492827 3% 54% 104
8 S1P RECEPTORS authKW 384772 2% 81% 54
9 SPHINGOSINE 1 PHOSPHATE S1P authKW 319361 1% 71% 51
10 S1P1 authKW 308662 1% 78% 45

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 3938 19% 0% 646
2 Biochemistry & Molecular Biology 3367 29% 0% 991
3 Immunology 2154 14% 0% 467
4 Transplantation 1574 5% 0% 166
5 Chemistry, Medicinal 1209 6% 0% 216
6 Pharmacology & Pharmacy 1163 13% 0% 451
7 Biophysics 743 6% 0% 220
8 Hematology 355 4% 0% 135
9 Oncology 344 7% 0% 253
10 Peripheral Vascular Diseases 245 3% 0% 112

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOMEMBRANE BIOFUNCT CHEM 126755 1% 31% 47
2 CELLULAR MOL REGULAT 80565 1% 20% 46
3 GENET DEV DIS BRANCH 58234 1% 13% 49
4 GENET DIS DEV BRANCH 39783 0% 75% 6
5 EXPT SURG BIOENGN 31854 0% 23% 16
6 IMMUNOL 3 28930 0% 55% 6
7 HELEN L DORRIS CHILD ADOLESCENT NEUROPSYCHIAT D 28507 0% 32% 10
8 BIOACT LIPID PROGRAM 28290 0% 80% 4
9 TULANE PHARMACOL 28290 0% 80% 4
10 NOVARTIS PHARMA 27069 0% 44% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 16981 2% 3% 72
2 CELLULAR SIGNALLING 3511 1% 1% 42
3 MULTIPLE SCLEROSIS AND RELATED DISORDERS 3418 0% 3% 12
4 FASEB JOURNAL 3028 2% 1% 58
5 PROSTAGLANDINS & OTHER LIPID MEDIATORS 2549 1% 1% 23
6 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1851 2% 0% 75
7 ACS MEDICINAL CHEMISTRY LETTERS 1829 0% 1% 17
8 JOURNAL OF BIOLOGICAL CHEMISTRY 1807 5% 0% 189
9 MULTIPLE SCLEROSIS JOURNAL 1474 1% 1% 20
10 TRANSPLANTATION PROCEEDINGS 1383 2% 0% 83

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SPHINGOSINE 1 PHOSPHATE 4877354 24% 66% 842 Search SPHINGOSINE+1+PHOSPHATE Search SPHINGOSINE+1+PHOSPHATE
2 FTY720 2331531 10% 79% 334 Search FTY720 Search FTY720
3 SPHINGOSINE KINASE 2004054 8% 78% 290 Search SPHINGOSINE+KINASE Search SPHINGOSINE+KINASE
4 FINGOLIMOD 995940 6% 55% 205 Search FINGOLIMOD Search FINGOLIMOD
5 SPHINGOSINE KINASE 1 660174 3% 77% 97 Search SPHINGOSINE+KINASE+1 Search SPHINGOSINE+KINASE+1
6 SPHINGOSINE 1 PHOSPHATE RECEPTOR 495189 2% 81% 69 Search SPHINGOSINE+1+PHOSPHATE+RECEPTOR Search SPHINGOSINE+1+PHOSPHATE+RECEPTOR
7 S1P 492827 3% 54% 104 Search S1P Search S1P
8 S1P RECEPTORS 384772 2% 81% 54 Search S1P+RECEPTORS Search S1P+RECEPTORS
9 SPHINGOSINE 1 PHOSPHATE S1P 319361 1% 71% 51 Search SPHINGOSINE+1+PHOSPHATE+S1P Search SPHINGOSINE+1+PHOSPHATE+S1P
10 S1P1 308662 1% 78% 45 Search S1P1 Search S1P1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VOGT, D , STARK, H , (2017) THERAPEUTIC STRATEGIES AND PHARMACOLOGICAL TOOLS INFLUENCING S1P SIGNALING AND METABOLISM.MEDICINAL RESEARCH REVIEWS. VOL. 37. ISSUE 1. P. 3 -51 323 75% 0
2 ALSHAKER, H , SAUER, L , MONTEIL, D , OTTAVIANI, S , SRIVATS, S , BOHLER, T , PCHEJETSKI, D , (2013) THERAPEUTIC POTENTIAL OF TARGETING SK1 IN HUMAN CANCERS.ROLE OF SPHINGOLIPIDS IN CANCER DEVELOPMENT AND THERAPY. VOL. 117. ISSUE . P. 143-200 268 87% 18
3 TAKABE, K , PAUGH, SW , MILSTIEN, S , SPIEGEL, S , (2008) "INSIDE-OUT" SIGNALING OF SPHINGOSINE-1-PHOSPHATE: THERAPEUTIC TARGETS.PHARMACOLOGICAL REVIEWS. VOL. 60. ISSUE 2. P. 181-195 168 88% 300
4 BIGAUD, M , GUERINI, D , BILLICH, A , BASSILANA, F , BRINKMANN, V , (2014) SECOND GENERATION S1P PATHWAY MODULATORS: RESEARCH STRATEGIES AND CLINICAL DEVELOPMENTS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1841. ISSUE 5. P. 745-758 162 93% 39
5 SCHUCHARDT, M , TOLLE, M , PRUFER, J , VAN DER GIET, M , (2011) PHARMACOLOGICAL RELEVANCE AND POTENTIAL OF SPHINGOSINE 1-PHOSPHATE IN THE VASCULAR SYSTEM.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 163. ISSUE 6. P. 1140 -1162 231 84% 27
6 WHITE, C , ALSHAKER, H , COOPER, C , WINKLER, M , PCHEJETSKI, D , (2016) THE EMERGING ROLE OF FTY720 (FINGOLIMOD) IN CANCER TREATMENT.ONCOTARGET. VOL. 7. ISSUE 17. P. 23106 -23127 188 80% 2
7 PYNE, NJ , PYNE, S , (2010) SPHINGOSINE 1-PHOSPHATE AND CANCER.NATURE REVIEWS CANCER. VOL. 10. ISSUE 7. P. 489 -503 145 77% 305
8 BRINKMANN, V , (2007) SPHINGOSINE 1-PHOSPHATE RECEPTORS IN HEALTH AND DISEASE: MECHANISTIC INSIGHTS FROM GENE DELETION STUDIES AND REVERSE PHARMACOLOGY.PHARMACOLOGY & THERAPEUTICS. VOL. 115. ISSUE 1. P. 84-105 157 83% 280
9 MARFE, G , MIRONE, G , SHUKLA, A , DI STEFANO, C , (2015) SPHINGOSINE KINASES SIGNALLING IN CARCINOGENESIS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 4. P. 300 -314 166 86% 5
10 TAHA, TA , HANNUN, YA , OBEID, LM , (2006) SPHINGOSINE KINASE: BIOCHEMICAL AND CELLULAR REGULATION AND ROLE IN DISEASE.JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 39. ISSUE 2. P. 113-131 165 89% 182

Classes with closest relation at Level 1


Rank Class id link
1 32560 APOLIPOPROTEIN M//APOM//COMPREHENS
2 3518 LYSOPHOSPHATIDIC ACID//AUTOTAXIN//LPA RECEPTOR
3 381 CERAMIDE//SPHINGOLIPIDS//SPHINGOMYELINASE
4 17764 LYSOPHOSPHATIDYLCHOLINE//SPHINGOSYLPHOSPHORYLCHOLINE//GPR4
5 27422 ALKALINE SPHINGOMYELINASE//BIOMED B11//4 8 SPHINGADIENINE
6 11464 LONG CHAIN BASE//SPHINGOLIPIDS//AUREOBASIDIN A
7 10439 CEREBROSIDE//JASPINE B//PHYTOSPHINGOSINE
8 15024 FIBROBLASTIC RETICULAR CELLS//INTRAVITAL IMAGING//LYMPHOCYTE BIOL SECT
9 31248 ANESTHET//CHANG GUNG MEM HOSP LIN KOU//APOPTOSIS INHIBITOR 5
10 20553 KAITOCEPHALIN//ALPHA SUBSTITUTED SERINE//CONAGENIN

Go to start page