Class information for:
Level 1: OSMOLYTES//PREFERENTIAL INTERACTIONS//PREFERENTIAL HYDRATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9378 1161 45.9 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
219 3       PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS//PROTEIN FOLDING//PROTEIN STRUCTURE PREDICTION 50409
1067 2             ANGIOGENIN//RIBONUCLEASE//MOLTEN GLOBULE 9981
9378 1                   OSMOLYTES//PREFERENTIAL INTERACTIONS//PREFERENTIAL HYDRATION 1161

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OSMOLYTES authKW 476335 10% 16% 111
2 PREFERENTIAL INTERACTIONS authKW 388002 2% 51% 29
3 PREFERENTIAL HYDRATION authKW 237500 1% 53% 17
4 COUNTERACTING EFFECTS authKW 131497 0% 100% 5
5 TRANSFER FREE ENERGY authKW 113946 1% 33% 13
6 PREFERENTIAL EXCLUSION authKW 112203 1% 53% 8
7 THERMAL UNFOLDING OF PROTEIN authKW 105197 0% 100% 4
8 OSMOPHOBIC EFFECT authKW 78898 0% 100% 3
9 SIMULATED HONEY SUGAR COCKTAIL authKW 78898 0% 100% 3
10 TMAO authKW 76824 1% 19% 15

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Physical 3416 37% 0% 430
2 Biochemistry & Molecular Biology 3320 45% 0% 525
3 Biophysics 3262 20% 0% 230
4 Physics, Atomic, Molecular & Chemical 1037 13% 0% 149
5 Thermodynamics 103 3% 0% 35
6 Chemistry, Multidisciplinary 98 9% 0% 105
7 Chemistry, Applied 42 3% 0% 30
8 Biochemical Research Methods 32 3% 0% 32
9 Biotechnology & Applied Microbiology 22 3% 0% 40
10 Chemistry, Analytical 4 2% 0% 29

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BASIC CLIN PHYSIOL 52599 0% 100% 2
2 FUTU STUDIES HLTH BIOSTAT EPIDEMIO 52599 0% 100% 2
3 GENET QUIM CELULAR 52599 0% 100% 2
4 INTERDISCIPLINARY BASIC SCI 39276 2% 7% 21
5 BIOINFORMAT BIOENGN PROGRAM 35064 0% 67% 2
6 SPE OCHIM INFRAROUGE RAMANUMR A8516 35064 0% 67% 2
7 DEEP COMP 33810 0% 43% 3
8 BIOMOL GRPBIOCHEM PROGRAMME 27387 0% 21% 5
9 BIODYMIA BIOINGN DYNAM MICROBIENNE AUX INTE 26299 0% 100% 1
10 CHEM ENGN ECCH 111 26299 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHYSICAL CHEMISTRY 20117 5% 1% 57
2 JOURNAL OF PHYSICAL CHEMISTRY B 13562 12% 0% 141
3 PROTEIN SCIENCE 5384 3% 1% 36
4 BIOCHEMISTRY 3899 8% 0% 90
5 BIOPOLYMERS 2493 2% 0% 25
6 BIOPHYSICAL JOURNAL 1893 3% 0% 38
7 PHYSICAL CHEMISTRY CHEMICAL PHYSICS 1502 3% 0% 40
8 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 1305 2% 0% 18
9 PROTEIN AND PEPTIDE LETTERS 1235 1% 0% 11
10 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 983 1% 0% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OSMOLYTES 476335 10% 16% 111 Search OSMOLYTES Search OSMOLYTES
2 PREFERENTIAL INTERACTIONS 388002 2% 51% 29 Search PREFERENTIAL+INTERACTIONS Search PREFERENTIAL+INTERACTIONS
3 PREFERENTIAL HYDRATION 237500 1% 53% 17 Search PREFERENTIAL+HYDRATION Search PREFERENTIAL+HYDRATION
4 COUNTERACTING EFFECTS 131497 0% 100% 5 Search COUNTERACTING+EFFECTS Search COUNTERACTING+EFFECTS
5 TRANSFER FREE ENERGY 113946 1% 33% 13 Search TRANSFER+FREE+ENERGY Search TRANSFER+FREE+ENERGY
6 PREFERENTIAL EXCLUSION 112203 1% 53% 8 Search PREFERENTIAL+EXCLUSION Search PREFERENTIAL+EXCLUSION
7 THERMAL UNFOLDING OF PROTEIN 105197 0% 100% 4 Search THERMAL+UNFOLDING+OF+PROTEIN Search THERMAL+UNFOLDING+OF+PROTEIN
8 OSMOPHOBIC EFFECT 78898 0% 100% 3 Search OSMOPHOBIC+EFFECT Search OSMOPHOBIC+EFFECT
9 SIMULATED HONEY SUGAR COCKTAIL 78898 0% 100% 3 Search SIMULATED+HONEY+SUGAR+COCKTAIL Search SIMULATED+HONEY+SUGAR+COCKTAIL
10 TMAO 76824 1% 19% 15 Search TMAO Search TMAO

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CANCHI, DR , GARCIA, AE , (2013) COSOLVENT EFFECTS ON PROTEIN STABILITY.ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 64. VOL. 64. ISSUE . P. 273-293 72 67% 102
2 SARMA, R , PAUL, S , (2013) EXPLORING THE MOLECULAR MECHANISM OF TRIMETHYLAMINE-N-OXIDE'S ABILITY TO COUNTERACT THE PROTEIN DENATURING EFFECTS OF UREA.JOURNAL OF PHYSICAL CHEMISTRY B. VOL. 117. ISSUE 18. P. 5691-5704 49 91% 13
3 GANGULY, P , VAN DER VEGT, NFA , SHEA, JE , (2016) HYDROPHOBIC ASSOCIATION IN MIXED UREA-TMAO SOLUTIONS.JOURNAL OF PHYSICAL CHEMISTRY LETTERS. VOL. 7. ISSUE 15. P. 3052 -3059 47 77% 3
4 ROSGEN, J , (2015) SYNERGY IN PROTEIN-OSMOLYTE MIXTURES.JOURNAL OF PHYSICAL CHEMISTRY B. VOL. 119. ISSUE 1. P. 150 -157 57 71% 4
5 RAHMAN, S , WAREPAM, M , SINGH, LR , DAR, TA , (2015) A CURRENT PERSPECTIVE ON THE COMPENSATORY EFFECTS OF UREA AND METHYLAMINE ON PROTEIN STABILITY AND FUNCTION.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. VOL. 119. ISSUE 2. P. 129 -136 66 65% 0
6 CANCHI, DR , JAYASIMHA, P , RAU, DC , MAKHATADZE, GI , GARCIA, AE , (2012) MOLECULAR MECHANISM FOR THE PREFERENTIAL EXCLUSION OF TMAO FROM PROTEIN SURFACES.JOURNAL OF PHYSICAL CHEMISTRY B. VOL. 116. ISSUE 40. P. 12095-12104 48 77% 48
7 SARMA, R , PAUL, S , (2013) INTERACTIONS OF S-PEPTIDE ANALOGUE IN AQUEOUS UREA AND TRIMETHYLAMINE-N-OXIDE SOLUTIONS: A MOLECULAR DYNAMICS SIMULATION STUDY.JOURNAL OF CHEMICAL PHYSICS. VOL. 139. ISSUE 3. P. - 52 84% 1
8 ROSGEN, J , JACKSON-ATOGI, R , (2012) VOLUME EXCLUSION AND H-BONDING DOMINATE THE THERMODYNAMICS AND SOLVATION OF TRIMETHYLAMINE-N-OXIDE IN AQUEOUS UREA.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. VOL. 134. ISSUE 7. P. 3590 -3597 45 85% 35
9 PIERCE, V , KANG, M , ABURI, M , WEERASINGHE, S , SMITH, PE , (2008) RECENT APPLICATIONS OF KIRKWOOD-BUFF THEORY TO BIOLOGICAL SYSTEMS.CELL BIOCHEMISTRY AND BIOPHYSICS. VOL. 50. ISSUE 1. P. 1-22 73 59% 53
10 SINGH, LR , PODDAR, NK , DAR, TA , RAHMAN, S , KUMAR, R , AHMAD, F , (2011) FORTY YEARS OF RESEARCH ON OSMOLYTE-INDUCED PROTEIN FOLDING AND STABILITY.JOURNAL OF THE IRANIAN CHEMICAL SOCIETY. VOL. 8. ISSUE 1. P. 1 -23 94 44% 21

Classes with closest relation at Level 1


Rank Class id link
1 11968 HOFMEISTER SERIES//CHONGQING SOIL MULTISCALE INTER IAL PRO//HOFMEISTER EFFECT
2 11355 MACROMOLECULAR CROWDING//THERMODYNAMIC NONIDEALITY//IN CELL NMR
3 6696 DIPARTIMENTO SCI BIOL AMBIENTALI//CONVERGENCE TEMPERATURES//WORK OF CAVITY CREATION
4 27408 HALOPHILIC//HALOPHILIC ADAPTATION//PL MOL MICROBIOL
5 21401 HUMAN HYALINE CARTILAGE//PROTEIN MELTING DOMAINS//THERMAL SHIFT ASSAY
6 5455 MOLTEN GLOBULE//ALPHA LACTALBUMIN//APOMYOGLOBIN
7 12936 HYPERTONICITY//NFAT5//ORGANIC OSMOLYTES
8 8237 UMR 1600//CHEMICAL SHIFT IN H 1 NMR//ETHANOL WATER CLUSTER
9 9771 PRESSURE DENATURATION//HIGH P SURE PROT//U128
10 8183 INCLUSION BODIES//PROTEIN REFOLDING//REFOLDING

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