Class information for:
Level 1: PBPK MODELING//HIPPURIC ACID//METHYLHIPPURIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8450 1252 33.8 50%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
4 4 ENVIRONMENTAL SCIENCES//GEOSCIENCES, MULTIDISCIPLINARY//METEOROLOGY & ATMOSPHERIC SCIENCES 1766162
108 3       AIR POLLUTION//TOXICOLOGY//PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 71534
573 2             TOXICOLOGY//BENZENE//TRICHLOROETHYLENE 14358
8450 1                   PBPK MODELING//HIPPURIC ACID//METHYLHIPPURIC ACID 1252

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PBPK MODELING authKW 398542 6% 22% 73
2 HIPPURIC ACID authKW 338099 4% 27% 52
3 METHYLHIPPURIC ACID authKW 257590 1% 81% 13
4 BIOLOGICAL MONITORING authKW 238709 8% 9% 106
5 GRP RECH TOXICOL HUMAINE address 189200 1% 52% 15
6 TRIMETHYLBENZENE authKW 171460 1% 47% 15
7 PBPK authKW 129404 3% 14% 38
8 SANTE ENVIRONM SANTE TRAVAIL address 112508 2% 15% 30
9 INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH journal 102622 9% 4% 117
10 TOXICOKINETIC MODELING authKW 98350 1% 37% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 38935 52% 0% 656
2 Public, Environmental & Occupational Health 9467 36% 0% 448
3 Environmental Sciences 1871 20% 0% 249
4 Pharmacology & Pharmacy 1614 23% 0% 284
5 Medicine, Legal 1225 3% 0% 43
6 Chemistry, Analytical 216 7% 0% 89
7 Social Sciences, Mathematical Methods 173 2% 0% 20
8 Biochemical Research Methods 47 3% 0% 38
9 Mathematics, Interdisciplinary Applications 35 2% 0% 21
10 Mathematical & Computational Biology 8 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRP RECH TOXICOL HUMAINE 189200 1% 52% 15
2 SANTE ENVIRONM SANTE TRAVAIL 112508 2% 15% 30
3 CHAIR MATH MODELLING SYST TOXICOL 78039 0% 80% 4
4 GRP RECH TOXICOL HUMAINE TOXHUM 73163 0% 100% 3
5 OSAKA OCCUPAT HLTH SERV 63710 1% 29% 9
6 MED TRAVAIL HYG MILIEU 62518 1% 26% 10
7 ENVIRONM TOXICOL TECHNOL 50792 1% 21% 10
8 SERV REPERTOIRE TOXICOL 32516 0% 67% 2
9 TRONDHEIM INNOVAT 32516 0% 67% 2
10 ICF CONSULTING 32512 0% 33% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH 102622 9% 4% 117
2 BRITISH JOURNAL OF INDUSTRIAL MEDICINE 18064 3% 2% 34
3 TOXICOLOGY AND APPLIED PHARMACOLOGY 15051 6% 1% 78
4 REGULATORY TOXICOLOGY AND PHARMACOLOGY 14736 3% 1% 42
5 ARCHIVES OF TOXICOLOGY 13411 4% 1% 49
6 TOXICOLOGY LETTERS 10820 5% 1% 61
7 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES 9922 3% 1% 32
8 INDUSTRIAL HEALTH 8923 2% 2% 24
9 SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH 5674 2% 1% 25
10 AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL 5423 2% 1% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PBPK MODELING 398542 6% 22% 73 Search PBPK+MODELING Search PBPK+MODELING
2 HIPPURIC ACID 338099 4% 27% 52 Search HIPPURIC+ACID Search HIPPURIC+ACID
3 METHYLHIPPURIC ACID 257590 1% 81% 13 Search METHYLHIPPURIC+ACID Search METHYLHIPPURIC+ACID
4 BIOLOGICAL MONITORING 238709 8% 9% 106 Search BIOLOGICAL+MONITORING Search BIOLOGICAL+MONITORING
5 TRIMETHYLBENZENE 171460 1% 47% 15 Search TRIMETHYLBENZENE Search TRIMETHYLBENZENE
6 PBPK 129404 3% 14% 38 Search PBPK Search PBPK
7 TOXICOKINETIC MODELING 98350 1% 37% 11 Search TOXICOKINETIC+MODELING Search TOXICOKINETIC+MODELING
8 DIMETHYLHIPPURIC ACID 97551 0% 100% 4 Search DIMETHYLHIPPURIC+ACID Search DIMETHYLHIPPURIC+ACID
9 PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL 97499 2% 13% 30 Search PHYSIOLOGICALLY+BASED+PHARMACOKINETIC+MODEL Search PHYSIOLOGICALLY+BASED+PHARMACOKINETIC+MODEL
10 TOLUENE 95121 9% 4% 107 Search TOLUENE Search TOLUENE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SARI-MINODIER, I , TRUCHON, G , CHAREST-TARDIF, G , BERUBE, A , TARDIF, R , (2009) THE EFFECT OF WORKLOAD ON BIOLOGICAL MONITORING OF OCCUPATIONAL EXPOSURE TO TOLUENE AND N-HEXANE: CONTRIBUTION OF PHYSIOLOGICALLY BASED TOXICOKINETIC MODELING.JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE. VOL. 6. ISSUE 7. P. 415 -432 56 85% 1
2 CHIU, WA , BARTON, HA , DEWOSKIN, RS , SCHLOSSER, P , THOMPSON, CM , SONAWANE, B , LIPSCOMB, JC , KRISHNAN, K , (2007) EVALUATION OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR USE IN RISK ASSESSMENT.JOURNAL OF APPLIED TOXICOLOGY. VOL. 27. ISSUE 3. P. 218-237 70 62% 45
3 COSNIER, F , NUNGE, H , BROCHARD, C , BURGART, M , REMY, A , DECRET, MJ , COSSEC, B , CAMPO, P , (2014) IMPACT OF COEXPOSURE ON TOLUENE BIOMARKERS IN RATS.XENOBIOTICA. VOL. 44. ISSUE 3. P. 217-228 31 82% 0
4 CLEWELL, RA , CLEWELL, HJ , (2008) DEVELOPMENT AND SPECIFICATION OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR USE IN RISK ASSESSMENT.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 50. ISSUE 1. P. 129 -143 48 53% 45
5 IKEDA, M , UKAI, H , KAWAI, T , INOUE, O , MAEJIMA, Y , FUKUI, Y , OHASHI, F , OKAMOTO, S , TAKADA, S , SAKURAI, H , (2008) CHANGES IN CORRELATION COEFFICIENTS OF EXPOSURE MARKERS AS A FUNCTION OF INTENSITY OF OCCUPATIONAL EXPOSURE TO TOLUENE.TOXICOLOGY LETTERS. VOL. 179. ISSUE 3. P. 148-154 31 84% 6
6 YOSHIDA, T , (2010) ESTIMATION OF ABSORPTION OF AROMATIC HYDROCARBONS DIFFUSING FROM INTERIOR MATERIALS IN AUTOMOBILE CABINS BY INHALATION TOXICOKINETIC ANALYSIS IN RATS.JOURNAL OF APPLIED TOXICOLOGY. VOL. 30. ISSUE 6. P. 525-535 36 67% 2
7 COSNIER, F , COSSEC, B , BURGART, M , NUNGE, H , BROCHARD, C , DECRET, MJ , REMY, A , (2013) BIOMARKERS OF TOLUENE EXPOSURE IN RATS: MERCAPTURIC ACIDS VERSUS TRADITIONAL INDICATORS (URINARY HIPPURIC ACID AND O-CRESOL AND BLOOD TOLUENE).XENOBIOTICA. VOL. 43. ISSUE 8. P. 651-660 29 73% 5
8 UKAI, H , KAWAI, T , INOUE, O , MAEJIMA, Y , FUKUI, Y , OHASHI, F , OKAMOTO, S , TAKADA, S , SAKURAI, H , IKEDA, M , (2007) COMPARATIVE EVALUATION OF BIOMARKERS OF OCCUPATIONAL EXPOSURE TO TOLUENE.INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH. VOL. 81. ISSUE 1. P. 81 -93 26 87% 19
9 VALCKE, M , HADDAD, S , (2015) ASSESSING HUMAN VARIABILITY IN KINETICS FOR EXPOSURES TO MULTIPLE ENVIRONMENTAL CHEMICALS: A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING CASE STUDY WITH DICHLOROMETHANE, BENZENE, TOLUENE, ETHYLBENZENE, AND M-XYLENE.JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES. VOL. 78. ISSUE 7. P. 409 -431 31 55% 4
10 IMBRIANI, M , GHITTORI, S , (2005) GASES AND ORGANIC SOLVENTS IN URINE AS BIOMARKERS OF OCCUPATIONAL EXPOSURE: A REVIEW.INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH. VOL. 78. ISSUE 1. P. 1-19 40 55% 40

Classes with closest relation at Level 1


Rank Class id link
1 13626 STYRENE 7 8 OXIDE//STYRENE//STYRENE OXIDE
2 22776 JET FUEL//JP 8 JET FUEL//JP 8
3 25623 MATH THEORET STAT//1 1 2 TRICHLORO 1 2 2 TRIFLUOROETHANE FC 113//AEROSP MED HOSP
4 9089 NEUROBEHAVIORAL TESTING//TETRACHLOROETHYLENE//SOLVENT EXPOSURE
5 16328 CHLOROFORM//LOUISIANA TOXICOL//HEPATOCELLULAR REGENERATION
6 6689 INHALANT ABUSE//INHALANTS//VOLATILE SUBSTANCE ABUSE
7 13582 2 5 HEXANEDIONE//GAMMA DIKETONE NEUROPATHY//1 2 DIACETYLBENZENE
8 3604 BENZENE//TRANS TRANS MUCONIC ACID//S PHENYLMERCAPTURIC ACID
9 20680 FLASH EVOKED POTENTIALS//GENERALIZED SEIZURE ACTIVITY//NEUROTOXICITE
10 10654 INTERSPECIES SCALING//VOLUME OF DISTRIBUTION//STEADY STATE VOLUME OF DISTRIBUTION

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