Class information for:
Level 1: 5 HT3 RECEPTOR//5 HT3 RECEPTOR ANTAGONIST//5 HT3

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8376 1260 38.7 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
218 2             SEROTONIN//5 HT1A RECEPTOR//5 HT2A RECEPTOR 20633
8376 1                   5 HT3 RECEPTOR//5 HT3 RECEPTOR ANTAGONIST//5 HT3 1260

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 5 HT3 RECEPTOR authKW 2481170 20% 40% 255
2 5 HT3 RECEPTOR ANTAGONIST authKW 525988 7% 26% 84
3 5 HT3 authKW 458892 4% 38% 50
4 5 HT3 RECEPTOR AGONIST authKW 237473 1% 70% 14
5 5 HT3A authKW 205259 1% 71% 12
6 LIGAND GATED ION CHANNEL authKW 202674 5% 14% 59
7 H 3GRANISETRON authKW 193862 1% 100% 8
8 5 HT3B authKW 172320 1% 89% 8
9 CONTINUOUS COCAINE authKW 172320 1% 89% 8
10 ONDANSETRON authKW 171921 6% 9% 81

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 10457 53% 0% 667
2 Neurosciences 4794 37% 0% 462
3 Chemistry, Medicinal 1611 11% 0% 141
4 Behavioral Sciences 675 6% 0% 71
5 Psychiatry 497 8% 0% 103
6 Biochemistry & Molecular Biology 113 13% 0% 158
7 Substance Abuse 75 1% 0% 17
8 Physiology 60 3% 0% 43
9 Chemistry, Organic 37 4% 0% 53
10 Biophysics 7 2% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FD 3 91332 1% 54% 7
2 DRUG DISCOVERY MOL CHEM S 48466 0% 100% 2
3 DRUG DISCOVERY MOLEC DESIGN 48466 0% 100% 2
4 NEUROENDOCRINOL NEURODYNAM 48466 0% 100% 2
5 PHARMACOLCELLULAR MOL NEUROPHARMACOL 48466 0% 100% 2
6 KLIN ANASTHESIOL SPEZIELLE INTENS MED 35629 0% 29% 5
7 INTERDIPARTIMENTALE ANAL DETERMINAZIONI STR 32309 0% 67% 2
8 NCOUNTER CORE IL 32309 0% 67% 2
9 ADV LIGHT MICROSCOPY IL CELL BIOL CELL BIOPH 24233 0% 100% 1
10 AFFAIRS PROF 24233 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 10939 9% 0% 113
2 NEUROPHARMACOLOGY 9887 5% 1% 62
3 BRITISH JOURNAL OF PHARMACOLOGY 6063 5% 0% 67
4 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 4437 4% 0% 48
5 PSYCHOPHARMACOLOGY 3825 3% 0% 44
6 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 2267 2% 0% 24
7 EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION 2247 1% 1% 10
8 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 1969 3% 0% 42
9 CNS DRUG REVIEWS 1332 0% 2% 3
10 RECEPTORS & CHANNELS 1227 0% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 5 HT3 RECEPTOR 2481170 20% 40% 255 Search 5+HT3+RECEPTOR Search 5+HT3+RECEPTOR
2 5 HT3 RECEPTOR ANTAGONIST 525988 7% 26% 84 Search 5+HT3+RECEPTOR+ANTAGONIST Search 5+HT3+RECEPTOR+ANTAGONIST
3 5 HT3 458892 4% 38% 50 Search 5+HT3 Search 5+HT3
4 5 HT3 RECEPTOR AGONIST 237473 1% 70% 14 Search 5+HT3+RECEPTOR+AGONIST Search 5+HT3+RECEPTOR+AGONIST
5 5 HT3A 205259 1% 71% 12 Search 5+HT3A Search 5+HT3A
6 LIGAND GATED ION CHANNEL 202674 5% 14% 59 Search LIGAND+GATED+ION+CHANNEL Search LIGAND+GATED+ION+CHANNEL
7 H 3GRANISETRON 193862 1% 100% 8 Search H+3GRANISETRON Search H+3GRANISETRON
8 5 HT3B 172320 1% 89% 8 Search 5+HT3B Search 5+HT3B
9 CONTINUOUS COCAINE 172320 1% 89% 8 Search CONTINUOUS+COCAINE Search CONTINUOUS+COCAINE
10 ONDANSETRON 171921 6% 9% 81 Search ONDANSETRON Search ONDANSETRON

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BARNES, NM , HALES, TG , LUMMIS, SCR , PETERS, JA , (2009) THE 5-HT3 RECEPTOR - THE RELATIONSHIP BETWEEN STRUCTURE AND FUNCTION.NEUROPHARMACOLOGY. VOL. 56. ISSUE 1. P. 273-284 130 71% 92
2 RAJKUMAR, R , MAHESH, R , (2010) THE AUSPICIOUS ROLE OF THE 5-HT3 RECEPTOR IN DEPRESSION: A PROBABLE NEURONAL TARGET?.JOURNAL OF PSYCHOPHARMACOLOGY. VOL. 24. ISSUE 4. P. 455 -469 117 64% 37
3 WALSTAB, J , RAPPOLD, G , NIESLER, B , (2010) 5-HT3 RECEPTORS: ROLE IN DISEASE AND TARGET OF DRUGS.PHARMACOLOGY & THERAPEUTICS. VOL. 128. ISSUE 1. P. 146-169 138 46% 84
4 LUMMIS, SCR , (2012) 5-HT3 RECEPTORS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 48. P. 40239-40245 62 79% 34
5 THOMPSON, AJ , LUMMIS, SCR , (2006) 5-HT3 RECEPTORS.CURRENT PHARMACEUTICAL DESIGN. VOL. 12. ISSUE 28. P. 3615-3630 87 60% 94
6 ENGLEMAN, EA , RODD, ZA , BELL, RL , MURPHY, JM , (2008) THE ROLE OF 5-HT3 RECEPTORS IN DRUG ABUSE AND AS A TARGET FOR PHARMACOTHERAPY.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 7. ISSUE 5. P. 454-467 105 48% 39
7 MACHU, TK , (2011) THERAPEUTICS OF 5-HT3 RECEPTOR ANTAGONISTS: CURRENT USES AND FUTURE DIRECTIONS.PHARMACOLOGY & THERAPEUTICS. VOL. 130. ISSUE 3. P. 338 -347 79 55% 24
8 GUPTA, D , PRABHAKAR, V , RADHAKRISHNAN, M , (2016) 5HT(3) RECEPTORS: TARGET FOR NEW ANTIDEPRESSANT DRUGS.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. VOL. 64. ISSUE . P. 311 -325 88 44% 0
9 GREENSHAW, AJ , SILVERSTONE, PH , (1997) THE NON-ANTIEMETIC USES OF SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS - CLINICAL PHARMACOLOGY AND THERAPEUTIC APPLICATIONS.DRUGS. VOL. 53. ISSUE 1. P. 20-39 96 59% 75
10 REEVES, DC , LUMMIS, SCR , (2002) THE MOLECULAR BASIS OF THE STRUCTURE AND FUNCTION OF THE 5-HT3 RECEPTOR: A MODEL LIGAND-GATED ION CHANNEL (REVIEW).MOLECULAR MEMBRANE BIOLOGY. VOL. 19. ISSUE 1. P. 11 -26 86 49% 134

Classes with closest relation at Level 1


Rank Class id link
1 32254 VORTIOXETINE//LU AA21004//BIS ARYL SULFANYLA MINE
2 7516 5 HT4 RECEPTOR//5 HT4//GR 113808
3 15628 F 13640//POLYSYNAPTIC REFLEX//5 HT RECEPTOR SUBTYPE
4 12805 EMESIS//SUNCUS MURINUS//EMESIS GRP
5 20838 SEROTONIN MODULATED ANTICONSOLIDATION PROTEIN//UMR 7521LN2C//3 2 CARBOXYPIPERAZIN 4 YLPROPYL 1 PHOSPHONIC ACID
6 11921 5 HT1B RECEPTOR//5 HT MODULINE//UNITE PHARMACOL NEUROIMMUNOENDOCRINIENNE
7 754 CYS LOOP RECEPTOR//NICOTINIC ACETYLCHOLINE RECEPTOR//RECEPTOR BIOL
8 3578 5 HT2C RECEPTOR//5 HT2A RECEPTOR//5 HT2C
9 1311 ANTIEMETICS//CHEMOTHERAPY INDUCED NAUSEA AND VOMITING//GRANISETRON
10 3624 5 HT1A RECEPTOR//BUSPIRONE//8 OH DPAT

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