Class information for:
Level 1: TRAMADOL//TAPENTADOL//O DESMETHYLTRAMADOL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8337 1264 30.2 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
59 3       ANESTHESIOLOGY//PAIN//CHRONIC PAIN 88506
2563 2             TRAMADOL//DIPYRONE//TAPENTADOL 3711
8337 1                   TRAMADOL//TAPENTADOL//O DESMETHYLTRAMADOL 1264

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRAMADOL authKW 7305132 45% 53% 567
2 TAPENTADOL authKW 923995 5% 65% 59
3 O DESMETHYLTRAMADOL authKW 634847 2% 91% 29
4 ANALGESICS OPIOID TRAMADOL authKW 367423 1% 89% 17
5 TRAMADOL HYDROCHLORIDE authKW 212948 2% 38% 23
6 RUSH PAIN address 169093 1% 100% 7
7 MED AFFAIRS EUROPE AUSTRALIA address 144937 0% 100% 6
8 N DESMETHYLTRAMADOL authKW 144937 0% 100% 6
9 TAPENTADOL PROLONGED RELEASE authKW 144937 0% 100% 6
10 CAS 36282 47 0 authKW 124230 0% 86% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Anesthesiology 13507 20% 0% 250
2 Pharmacology & Pharmacy 5122 38% 0% 479
3 Chemistry, Analytical 374 9% 0% 111
4 Medicine, Legal 327 2% 0% 23
5 Veterinary Sciences 267 6% 0% 78
6 Medicine, General & Internal 234 8% 0% 100
7 Clinical Neurology 196 7% 0% 88
8 Toxicology 181 4% 0% 55
9 Biochemical Research Methods 179 5% 0% 62
10 Substance Abuse 166 2% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RUSH PAIN 169093 1% 100% 7
2 MED AFFAIRS EUROPE AUSTRALIA 144937 0% 100% 6
3 LAFAA CONTRACT 72468 0% 100% 3
4 NORTHSHORE PAIN 72468 0% 100% 3
5 GLOBAL PRECLIN DEV 54410 1% 17% 13
6 CBMA MOL BIOL ENVIRONM 48312 0% 100% 2
7 GLOBAL BIOMETR GRUNENTHAL INNOVAT 48312 0% 100% 2
8 GRUNENTHAL INNOVAT GLOBAL BIOMETR 48312 0% 100% 2
9 PAEDIAT SURG INTENS THER Y 48312 0% 100% 2
10 VISCERAL PHYSIOL 43479 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF ANAESTHESIOLOGY 4205 2% 1% 23
2 CURRENT MEDICAL RESEARCH AND OPINION 2833 2% 1% 23
3 CLINICAL DRUG INVESTIGATION 2465 1% 1% 15
4 ANESTHESIA AND ANALGESIA 2461 3% 0% 39
5 ANAESTHESIST 2442 2% 0% 21
6 PAIN PRACTICE 2430 1% 1% 8
7 EUROPEAN JOURNAL OF PAIN 2282 1% 1% 14
8 CLINICAL THERAPEUTICS 2116 2% 0% 21
9 BRITISH JOURNAL OF ANAESTHESIA 2054 2% 0% 28
10 JOURNAL OF PAIN RESEARCH 2011 0% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRAMADOL 7305132 45% 53% 567 Search TRAMADOL Search TRAMADOL
2 TAPENTADOL 923995 5% 65% 59 Search TAPENTADOL Search TAPENTADOL
3 O DESMETHYLTRAMADOL 634847 2% 91% 29 Search O+DESMETHYLTRAMADOL Search O+DESMETHYLTRAMADOL
4 ANALGESICS OPIOID TRAMADOL 367423 1% 89% 17 Search ANALGESICS+OPIOID+TRAMADOL Search ANALGESICS+OPIOID+TRAMADOL
5 TRAMADOL HYDROCHLORIDE 212948 2% 38% 23 Search TRAMADOL+HYDROCHLORIDE Search TRAMADOL+HYDROCHLORIDE
6 N DESMETHYLTRAMADOL 144937 0% 100% 6 Search N+DESMETHYLTRAMADOL Search N+DESMETHYLTRAMADOL
7 TAPENTADOL PROLONGED RELEASE 144937 0% 100% 6 Search TAPENTADOL+PROLONGED+RELEASE Search TAPENTADOL+PROLONGED+RELEASE
8 CAS 36282 47 0 124230 0% 86% 6 Search CAS+36282+47+0 Search CAS+36282+47+0
9 CAS 27203 92 5 120780 0% 100% 5 Search CAS+27203+92+5 Search CAS+27203+92+5
10 O DEMETHYLTRAMADOL 120780 0% 100% 5 Search O+DEMETHYLTRAMADOL Search O+DEMETHYLTRAMADOL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GROND, S , SABLOTZKI, A , (2004) CLINICAL PHARMACOLOGY OF TRAMADOL.CLINICAL PHARMACOKINETICS. VOL. 43. ISSUE 13. P. 879-923 181 80% 383
2 LEPPERT, W , (2009) TRAMADOL AS AN ANALGESIC FOR MILD TO MODERATE CANCER PAIN.PHARMACOLOGICAL REPORTS. VOL. 61. ISSUE 6. P. 978 -992 63 82% 47
3 SHIPTON, EA , (2000) TRAMADOL - PRESENT AND FUTURE.ANAESTHESIA AND INTENSIVE CARE. VOL. 28. ISSUE 4. P. 363 -374 77 81% 97
4 SCOTT, LJ , PERRY, CM , (2000) TRAMADOL - A REVIEW OF ITS USE IN PERIOPERATIVE PAIN.DRUGS. VOL. 60. ISSUE 1. P. 139 -176 65 73% 247
5 RADBRUCH, L , GROND, S , LEHMANN, KA , (1996) A RISK-BENEFIT ASSESSMENT OF TRAMADOL IN THE MANAGEMENT OF PAIN.DRUG SAFETY. VOL. 15. ISSUE 1. P. 8-29 65 92% 65
6 MARZUILLO, P , CALLIGARIS, L , BARBI, E , (2014) TRAMADOL CAN SELECTIVELY MANAGE MODERATE PAIN IN CHILDREN FOLLOWING EUROPEAN ADVICE LIMITING CODEINE USE.ACTA PAEDIATRICA. VOL. 103. ISSUE 11. P. 1110 -1116 43 88% 1
7 LEE, CR , MCTAVISH, D , SORKIN, EM , (1993) TRAMADOL - A PRELIMINARY REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC POTENTIAL IN ACUTE AND CHRONIC PAIN STATES.DRUGS. VOL. 46. ISSUE 2. P. 313-340 53 88% 299
8 LASSEN, D , DAMKIER, P , BROSEN, K , (2015) THE PHARMACOGENETICS OF TRAMADOL.CLINICAL PHARMACOKINETICS. VOL. 54. ISSUE 8. P. 825 -836 45 66% 8
9 LEPPERT, W , LUCZAK, J , (2005) THE ROLE OF TRAMADOL IN CANCER PAIN TREATMENT - A REVIEW.SUPPORTIVE CARE IN CANCER. VOL. 13. ISSUE 1. P. 5-17 44 92% 49
10 GONG, L , STAMER, UM , TZVETKOV, MV , ALTMAN, RB , KLEIN, TE , (2014) PHARMGKB SUMMARY: TRAMADOL PATHWAY.PHARMACOGENETICS AND GENOMICS. VOL. 24. ISSUE 7. P. 374 -380 43 73% 6

Classes with closest relation at Level 1


Rank Class id link
1 17600 INTRAVENOUS ACETAMINOPHEN//PARACETAMOL//PROPACETAMOL
2 9386 PAIN NUFFIELD ANAESTHET//THIRD MOLAR SURGERY//DENTAL PAIN
3 6475 VETERINARY ANAESTHESIA AND ANALGESIA//CARPROFEN//ROBENACOXIB
4 1265 OPIOIDS//CHRONIC NONCANCER PAIN//PRESCRIPTION OPIOIDS
5 8087 KETOROLAC//ANALGESIA PREEMPTIVE//PREEMPTIVE ANALGESIA
6 4004 NEUROPATHIC PAIN//POSTHERPETIC NEURALGIA//PREGABALIN
7 10049 PATIENT CONTROLLED ANALGESIA//ACUTE PAIN SERVICE//ANALGESIA PATIENT CONTROLLED
8 16253 AMITRIPTYLINE//OPIOID RECEPTOR SUBTYPES//PHYSIOL PHARMACOL NERVOUS SYST
9 18445 SEROTONIN SYNDROME//SEROTONIN TOXICITY//5 HT ENHANCING DRUG
10 7391 MORPHINE 6 GLUCURONIDE//OXYCODONE//MORPHINE 3 GLUCURONIDE

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