Class information for:
Level 1: PINDOLOL//VILAZODONE//5 HT1A RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7952 1310 48.8 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
218 2             SEROTONIN//5 HT1A RECEPTOR//5 HT2A RECEPTOR 20633
7952 1                   PINDOLOL//VILAZODONE//5 HT1A RECEPTOR 1310

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PINDOLOL authKW 445556 5% 28% 69
2 VILAZODONE authKW 386147 2% 61% 27
3 5 HT1A RECEPTOR authKW 271635 10% 9% 137
4 NEUROBIOL PSYCHIAT UNIT address 217421 2% 30% 31
5 ANTIDEPRESSANTS authKW 212330 21% 3% 276
6 5 HT1B RECEPTOR authKW 194221 4% 16% 51
7 WAY 100635 authKW 184611 4% 16% 49
8 5 HT1A AUTORECEPTORS authKW 183523 2% 38% 21
9 DORSAL RAPHE NUCLEUS authKW 154963 5% 10% 65
10 5 HT AUTORECEPTORS authKW 145876 1% 48% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 13714 59% 0% 774
2 Neurosciences 8728 48% 0% 623
3 Psychiatry 7295 27% 0% 358
4 Chemistry, Medicinal 967 9% 0% 114
5 Clinical Neurology 510 10% 0% 131
6 Behavioral Sciences 307 4% 0% 51
7 Chemistry, Organic 67 5% 0% 65
8 Psychology, Clinical 60 2% 0% 26
9 Psychology 15 1% 0% 16
10 Medicine, Research & Experimental 10 2% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOL PSYCHIAT UNIT 217421 2% 30% 31
2 ENVIRONM MOL HLTH SCI 93215 1% 33% 12
3 UP EAD MENRT 69923 0% 100% 3
4 G HAM PSYCHIAT INTENS CARE UNIT 46616 0% 100% 2
5 PSYCHOPHARMACOL EVALUAT UNIT 46616 0% 100% 2
6 RECH CROISSY 32620 1% 20% 7
7 BIOMONITORING SENSORING 32415 1% 17% 8
8 EA 3256 30661 0% 26% 5
9 EA 3544 27960 0% 20% 6
10 ABRAHAM RIBICOFF ILCLIN NEUROSCI UNIT 23308 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 15511 10% 0% 137
2 NEUROPHARMACOLOGY 12134 5% 1% 70
3 INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 10328 2% 2% 28
4 NEUROPSYCHOPHARMACOLOGY 8444 3% 1% 43
5 PSYCHOPHARMACOLOGY 7589 5% 1% 63
6 SYNAPSE 6352 2% 1% 30
7 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 5802 3% 1% 39
8 EUROPEAN NEUROPSYCHOPHARMACOLOGY 4948 2% 1% 22
9 PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 2704 2% 0% 24
10 JOURNAL OF NEUROCHEMISTRY 2619 4% 0% 49

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PINDOLOL 445556 5% 28% 69 Search PINDOLOL Search PINDOLOL
2 VILAZODONE 386147 2% 61% 27 Search VILAZODONE Search VILAZODONE
3 5 HT1A RECEPTOR 271635 10% 9% 137 Search 5+HT1A+RECEPTOR Search 5+HT1A+RECEPTOR
4 ANTIDEPRESSANTS 212330 21% 3% 276 Search ANTIDEPRESSANTS Search ANTIDEPRESSANTS
5 5 HT1B RECEPTOR 194221 4% 16% 51 Search 5+HT1B+RECEPTOR Search 5+HT1B+RECEPTOR
6 WAY 100635 184611 4% 16% 49 Search WAY+100635 Search WAY+100635
7 5 HT1A AUTORECEPTORS 183523 2% 38% 21 Search 5+HT1A+AUTORECEPTORS Search 5+HT1A+AUTORECEPTORS
8 DORSAL RAPHE NUCLEUS 154963 5% 10% 65 Search DORSAL+RAPHE+NUCLEUS Search DORSAL+RAPHE+NUCLEUS
9 5 HT AUTORECEPTORS 145876 1% 48% 13 Search 5+HT+AUTORECEPTORS Search 5+HT+AUTORECEPTORS
10 5 HT1B AUTORECEPTOR 142758 1% 88% 7 Search 5+HT1B+AUTORECEPTOR Search 5+HT1B+AUTORECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KINNEY, GG , TABER, MT , GRIBKOFF, VK , (2000) THE AUGMENTATION HYPOTHESIS FOR IMPROVEMENT OF ANTIDEPRESSANT THERAPY - IS PINDOLOL A SUITABLE CANDIDATE FOR TESTING THE ABILITY OF 5HT(1A) RECEPTOR ANTAGONISTS TO ENHANCE SSRI EFFICACY AND ONSET LATENCY?.MOLECULAR NEUROBIOLOGY. VOL. 21. ISSUE 3. P. 137-152 77 87% 28
2 HJORTH, S , BENGTSSON, HJ , KULLBERG, A , CARLZON, D , PEILOT, H , AUERBACH, SB , (2000) SEROTONIN AUTORECEPTOR FUNCTION AND ANTIDEPRESSANT DRUG ACTION.JOURNAL OF PSYCHOPHARMACOLOGY. VOL. 14. ISSUE 2. P. 177 -185 64 77% 128
3 DAWSON, LA , BROMIDGE, SM , (2008) 5-HT1 RECEPTOR AUGMENTATION STRATEGIES AS ENHANCED EFFICACY THERAPEUTICS FOR PSYCHIATRIC DISORDERS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 8. ISSUE 12. P. 1008 -1023 69 57% 21
4 DAWSON, LA , NGUYEN, HQ , SMITH, DI , SCHECHTER, LE , (2000) EFFECTS OF CHRONIC FLUOXETINE TREATMENT IN THE PRESENCE AND ABSENCE OF (+/-)PINDOLOL: A MICRODIALYSIS STUDY.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 130. ISSUE 4. P. 797 -804 43 93% 51
5 GUR, E , DREMENCOV, E , LERER, B , NEWMAN, ME , (1999) VENLAFAXINE: ACUTE AND CHRONIC EFFECTS ON 5-HYDROXYTRYPTAMINE LEVELS IN RAT BRAIN IN VIVO.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 372. ISSUE 1. P. 17-24 45 94% 31
6 GUILLOUX, JP , DAVID, DJP , GUIARD, BP , CHENU, F , REPERANT, C , TOTH, M , BOURIN, M , GARDIER, AM , (2006) BLOCKADE OF 5-HT1A RECEPTORS BY (+/-)-PINDOLOL POTENTIATES CORTICAL 5-HT OUTFLOW, BUT NOT ANTIDEPRESSANT-LIKE ACTIVITY OF PAROXETINE: MICRODIALYSIS AND BEHAVIORAL APPROACHES IN 5-HT1A RECEPTOR KNOCKOUT MICE.NEUROPSYCHOPHARMACOLOGY. VOL. 31. ISSUE 10. P. 2162-2172 45 74% 29
7 MURAKI, I , INOUE, T , KOYAMA, T , (2008) EFFECT OF CO-ADMINISTRATION OF THE SELECTIVE 5-HT1A RECEPTOR ANTAGONIST WAY 100,635 AND SELECTIVE 5-HT1B/1D RECEPTOR ANTAGONIST GR 127,935 ON ANXIOLYTIC EFFECT OF CITALOPRAM IN CONDITIONED FEAR STRESS IN THE RAT.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 586. ISSUE 1-3. P. 171-178 41 72% 11
8 ARTIGAS, F , ADELL, A , CELADA, P , (2006) PINDOLOL AUGMENTATION OF ANTIDEPRESSANT RESPONSE.CURRENT DRUG TARGETS. VOL. 7. ISSUE 2. P. 139 -147 47 59% 64
9 HERVAS, I , VILARO, MT , ROMERO, L , SCORZA, MC , MENGOD, G , ARTIGAS, F , (2001) DESENSITIZATION OF 5-HT1A AUTORECEPTORS BY A LOW CHRONIC FLUOXETINE DOSE EFFECT OF THE CONCURRENT ADMINISTRATION OF WAY-100635.NEUROPSYCHOPHARMACOLOGY. VOL. 24. ISSUE 1. P. 11-20 42 78% 75
10 HUGHES, ZA , STARR, KR , SCOTT, CM , NEWSON, MJ , SHARP, T , WATSON, JM , HAGAN, JJ , DAWSON, LA , (2007) SIMULTANEOUS BLOCKADE OF 5-HT1A/B RECEPTORS AND 5-HT TRANSPORTERS RESULTS IN ACUTE INCREASES IN EXTRACELLULAR 5-HT IN BOTH RATS AND GUINEA PIGS: IN VIVO CHARACTERIZATION OF THE NOVEL 5-HT1A/B RECEPTOR ANTAGONIST/5-HT TRANSPORT INHIBITOR SB-649915-B.PSYCHOPHARMACOLOGY. VOL. 192. ISSUE 1. P. 121-133 38 76% 12

Classes with closest relation at Level 1


Rank Class id link
1 11921 5 HT1B RECEPTOR//5 HT MODULINE//UNITE PHARMACOL NEUROIMMUNOENDOCRINIENNE
2 3624 5 HT1A RECEPTOR//BUSPIRONE//8 OH DPAT
3 30745 TRIPLE REUPTAKE INHIBITOR//DOV 216 303//TRIPLE UPTAKE INHIBITORS
4 32254 VORTIOXETINE//LU AA21004//BIS ARYL SULFANYLA MINE
5 23627 MOUSE FORCED SWIMMING//GALNAC ALPHA 1 3GALNAC LIPID//TAIL SUSPENSION TEST
6 12851 DORSAL RAPHE NUCLEUS//PET 1//MEDIAN RAPHE NUCLEUS
7 25750 CONE NEUROSURG//ALPHA METHYL L TRYPTOPHAN//SEROTONIN SYNTHESIS RATE
8 23948 MIRTAZAPINE//ORG 3770//MIRTAZAPINE ORG 3770
9 7414 TREATMENT RESISTANT DEPRESSION//RESISTANT DEPRESSION//LITHIUM AUGMENTATION
10 26382 DULOXETINE//DULOXETINE HYDROCHLORIDE//GLOBAL PHARMACOKINET PHARMACODYNAM TRIAL SIMULAT

Go to start page