Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
6479 | 1478 | 44.8 | 92% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
365 | 3 | MICROTUBULES//MITOSIS//KINETOCHORE | 34118 |
540 | 2 | KINETOCHORE//MITOSIS//CENTROSOME | 14738 |
6479 | 1 | AURORA KINASE//AURORA A//AURORA KINASE INHIBITOR | 1478 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | AURORA KINASE | authKW | 2338775 | 12% | 63% | 179 |
2 | AURORA A | authKW | 2071018 | 11% | 63% | 158 |
3 | AURORA KINASE INHIBITOR | authKW | 1276925 | 5% | 82% | 75 |
4 | AURORA B | authKW | 736533 | 5% | 44% | 81 |
5 | MLN8237 | authKW | 640405 | 2% | 100% | 31 |
6 | AURORA KINASE A | authKW | 631370 | 3% | 75% | 41 |
7 | TPX2 | authKW | 620094 | 3% | 73% | 41 |
8 | AURKA | authKW | 615160 | 3% | 66% | 45 |
9 | AZD1152 | authKW | 579117 | 2% | 97% | 29 |
10 | AURORA A KINASE | authKW | 552108 | 3% | 64% | 42 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Oncology | 8447 | 40% | 0% | 585 |
2 | Cell Biology | 3358 | 25% | 0% | 376 |
3 | Chemistry, Medicinal | 1377 | 10% | 0% | 143 |
4 | Biochemistry & Molecular Biology | 669 | 21% | 0% | 315 |
5 | Pharmacology & Pharmacy | 177 | 9% | 0% | 133 |
6 | Genetics & Heredity | 164 | 6% | 0% | 86 |
7 | Pathology | 95 | 3% | 0% | 44 |
8 | Medicine, Research & Experimental | 95 | 4% | 0% | 62 |
9 | Developmental Biology | 69 | 2% | 0% | 26 |
10 | Hematology | 63 | 3% | 0% | 42 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | GRP CYCLE CELLULAIRE | 134266 | 1% | 50% | 13 |
2 | REGULATORY RADIOBIOL | 113609 | 1% | 50% | 11 |
3 | MOL PATHOBIOCHEM | 56109 | 1% | 23% | 12 |
4 | CNRSUPR 41 | 41316 | 0% | 100% | 2 |
5 | DRUG DEV MANAGEMENT | 41316 | 0% | 100% | 2 |
6 | GRP CYCLE CELLULAIRE MED | 41316 | 0% | 100% | 2 |
7 | HORMONAL CARCINOGENSIS | 41316 | 0% | 100% | 2 |
8 | MICROBIOL CELL BIOL MCB | 41316 | 0% | 100% | 2 |
9 | UP RADIOSENSIT TUMORS NORMAL TISSUES EA2 | 41316 | 0% | 100% | 2 |
10 | GUIZHOU PROV REGENERAT MED | 40490 | 1% | 20% | 10 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | MOLECULAR CANCER THERAPEUTICS | 7672 | 3% | 1% | 39 |
2 | COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES | 6318 | 3% | 1% | 39 |
3 | INVESTIGATIONAL NEW DRUGS | 2310 | 1% | 1% | 17 |
4 | CLINICAL CANCER RESEARCH | 2168 | 3% | 0% | 40 |
5 | MOLECULAR CANCER | 1394 | 1% | 1% | 11 |
6 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1063 | 3% | 0% | 37 |
7 | CHEMICAL BIOLOGY & DRUG DESIGN | 997 | 1% | 1% | 9 |
8 | ONCOGENE | 915 | 2% | 0% | 29 |
9 | MOLECULAR BIOLOGY OF THE CELL | 863 | 1% | 0% | 19 |
10 | JOURNAL OF CELL BIOLOGY | 834 | 2% | 0% | 26 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | AURORA KINASE | 2338775 | 12% | 63% | 179 | Search AURORA+KINASE | Search AURORA+KINASE |
2 | AURORA A | 2071018 | 11% | 63% | 158 | Search AURORA+A | Search AURORA+A |
3 | AURORA KINASE INHIBITOR | 1276925 | 5% | 82% | 75 | Search AURORA+KINASE+INHIBITOR | Search AURORA+KINASE+INHIBITOR |
4 | AURORA B | 736533 | 5% | 44% | 81 | Search AURORA+B | Search AURORA+B |
5 | MLN8237 | 640405 | 2% | 100% | 31 | Search MLN8237 | Search MLN8237 |
6 | AURORA KINASE A | 631370 | 3% | 75% | 41 | Search AURORA+KINASE+A | Search AURORA+KINASE+A |
7 | TPX2 | 620094 | 3% | 73% | 41 | Search TPX2 | Search TPX2 |
8 | AURKA | 615160 | 3% | 66% | 45 | Search AURKA | Search AURKA |
9 | AZD1152 | 579117 | 2% | 97% | 29 | Search AZD1152 | Search AZD1152 |
10 | AURORA A KINASE | 552108 | 3% | 64% | 42 | Search AURORA+A+KINASE | Search AURORA+A+KINASE |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | MALUMBRES, M , DE CASTRO, IP , (2014) AURORA KINASE A INHIBITORS: PROMISING AGENTS IN ANTITUMORAL THERAPY.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 18. ISSUE 12. P. 1377 -1393 | 157 | 84% | 16 |
2 | YAN, M , WANG, CL , HE, B , YANG, MY , TONG, MY , LONG, ZJ , LIU, B , PENG, F , XU, LZ , ZHANG, Y , ET AL (2016) AURORA-A KINASE: A POTENT ONCOGENE AND TARGET FOR CANCER THERAPY.MEDICINAL RESEARCH REVIEWS. VOL. 36. ISSUE 6. P. 1036 -1079 | 180 | 76% | 0 |
3 | NIKONOVA, AS , ASTSATUROV, I , SEREBRIISKII, IG , DUNBRACK, RL , GOLEMIS, EA , (2013) AURORA A KINASE (AURKA) IN NORMAL AND PATHOLOGICAL CELL DIVISION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 70. ISSUE 4. P. 661 -687 | 142 | 60% | 80 |
4 | CICENAS, J , (2016) THE AURORA KINASE INHIBITORS IN CANCER RESEARCH AND THERAPY.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. VOL. 142. ISSUE 9. P. 1995 -2012 | 124 | 82% | 0 |
5 | DURLACHER, CT , LI, ZL , CHEN, XW , HE, ZX , ZHOU, SF , (2016) AN UPDATE ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF ALISERTIB, A SELECTIVE AURORA KINASE A INHIBITOR.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. VOL. 43. ISSUE 6. P. 585 -601 | 100 | 84% | 2 |
6 | LIBERTINI, S , ABAGNALE, A , PASSARO, C , BOTTA, G , PORTELLA, G , (2010) AURORA A AND B KINASES - TARGETS OF NOVEL ANTICANCER DRUGS.RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY. VOL. 5. ISSUE 3. P. 219-241 | 159 | 67% | 9 |
7 | GOLDENSON, B , CRISPINO, JD , (2015) THE AURORA KINASES IN CELL CYCLE AND LEUKEMIA.ONCOGENE. VOL. 34. ISSUE 5. P. 537 -545 | 94 | 66% | 32 |
8 | KATSHA, A , BELKHIRI, A , GOFF, L , EL-RIFAI, W , (2015) AURORA KINASE A IN GASTROINTESTINAL CANCERS: TIME TO TARGET.MOLECULAR CANCER. VOL. 14. ISSUE . P. - | 91 | 86% | 10 |
9 | FALCHOOK, GS , BASTIDA, CC , KURZROCK, R , (2015) AURORA KINASE INHIBITORS IN ONCOLOGY CLINICAL TRIALS: CURRENT STATE OF THE PROGRESS.SEMINARS IN ONCOLOGY. VOL. 42. ISSUE 6. P. 832 -848 | 89 | 83% | 6 |
10 | GAUTSCHI, O , HEIGHWAY, J , MACK, PC , PURNELL, PR , LARA, PN , GANDARA, DR , (2008) AURORA KINASES AS ANTICANCER DRUG TARGETS.CLINICAL CANCER RESEARCH. VOL. 14. ISSUE 6. P. 1639 -1648 | 70 | 91% | 255 |
Classes with closest relation at Level 1 |
Rank | Class id | link |
---|---|---|
1 | 1972 | SPINDLE ASSEMBLY CHECKPOINT//MAD2//CDC20 |
2 | 11497 | POLO LIKE KINASE 1//PLK1//POLO LIKE KINASE |
3 | 35189 | REVERSINE//TAK 778//PURMORPHAMINE |
4 | 10900 | CYTOKINESIS//CENTRAL SPINDLE//CENTRALSPINDLIN |
5 | 24379 | NEK2//NIMA//NEK6 |
6 | 23620 | KINESIN SPINDLE PROTEIN//EG5//KSP |
7 | 16660 | COFFIN LOWRY SYNDROME//RSK2//PHOSPHOHISTONE H3 |
8 | 3081 | CENTROSOME//CENTRIOLE//GAMMA TUBULIN |
9 | 1570 | EB1//MICROTUBULES//CHROMOSOME MOVEMENT |
10 | 3854 | SURVIVIN//YM155//SURVIVIN EXPRESSION |