Class information for:
Level 1: LINEZOLID//OXAZOLIDINONE//LINEZOLID RESISTANCE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6235 1510 29.5 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
73 3       MICROBIOLOGY//INFECTIOUS DISEASES//STAPHYLOCOCCUS AUREUS 82747
575 2             VANCOMYCIN//LINEZOLID//DAPTOMYCIN 14274
6235 1                   LINEZOLID//OXAZOLIDINONE//LINEZOLID RESISTANCE 1510

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LINEZOLID authKW 5785390 34% 56% 510
2 OXAZOLIDINONE authKW 1543869 14% 36% 211
3 LINEZOLID RESISTANCE authKW 500149 2% 85% 29
4 TEDIZOLID authKW 289080 2% 62% 23
5 EPEREZOLID authKW 181984 1% 100% 9
6 CFR GENE authKW 143788 1% 89% 8
7 CFR authKW 121722 1% 35% 17
8 G2576T MUTATION authKW 121322 0% 100% 6
9 RANBEZOLID authKW 121322 0% 100% 6
10 ZAAPS authKW 121322 0% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Infectious Diseases 18678 33% 0% 502
2 Microbiology 15202 42% 0% 634
3 Pharmacology & Pharmacy 8823 45% 0% 678
4 Chemistry, Medicinal 1956 11% 0% 170
5 Chemistry, Organic 381 9% 0% 132
6 Immunology 108 6% 0% 90
7 Critical Care Medicine 42 1% 0% 21
8 Pediatrics 40 3% 0% 43
9 Medicine, General & Internal 16 3% 0% 51
10 Chemistry, Analytical 7 3% 0% 39

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEV EVALUAT CHEM HERBAL DRUGS ANIM US 59458 1% 29% 10
2 FARM ANIM GENET 54614 2% 10% 28
3 ANTI INFECT GRP 40441 0% 100% 2
4 ANTIINFECT DISCOVERY GRP 40441 0% 100% 2
5 ASTRAZENECA DISCOVERY 40441 0% 100% 2
6 GLOBAL PRICING 40441 0% 100% 2
7 PHARMACOL 7250 209 205 40441 0% 100% 2
8 PROD LIFE CYCLE MANAGEMENT 40441 0% 100% 2
9 ANTI INFECT DISCOVERY GRP 26959 0% 67% 2
10 EA 1156 26959 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 39172 14% 1% 214
2 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 22482 8% 1% 118
3 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 17117 4% 1% 57
4 DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 9441 3% 1% 50
5 REVISTA ESPANOLA DE QUIMIOTERAPIA 4150 1% 2% 9
6 JOURNAL OF INFECTION AND CHEMOTHERAPY 3997 1% 1% 15
7 JOURNAL OF CHEMOTHERAPY 3919 1% 1% 22
8 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3408 4% 0% 66
9 SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 2380 2% 0% 25
10 CLINICAL INFECTIOUS DISEASES 2218 3% 0% 38

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LINEZOLID 5785390 34% 56% 510 Search LINEZOLID Search LINEZOLID
2 OXAZOLIDINONE 1543869 14% 36% 211 Search OXAZOLIDINONE Search OXAZOLIDINONE
3 LINEZOLID RESISTANCE 500149 2% 85% 29 Search LINEZOLID+RESISTANCE Search LINEZOLID+RESISTANCE
4 TEDIZOLID 289080 2% 62% 23 Search TEDIZOLID Search TEDIZOLID
5 EPEREZOLID 181984 1% 100% 9 Search EPEREZOLID Search EPEREZOLID
6 CFR GENE 143788 1% 89% 8 Search CFR+GENE Search CFR+GENE
7 CFR 121722 1% 35% 17 Search CFR Search CFR
8 G2576T MUTATION 121322 0% 100% 6 Search G2576T+MUTATION Search G2576T+MUTATION
9 RANBEZOLID 121322 0% 100% 6 Search RANBEZOLID Search RANBEZOLID
10 ZAAPS 121322 0% 100% 6 Search ZAAPS Search ZAAPS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MENDES, RE , DESHPANDE, LM , JONES, RN , (2014) LINEZOLID UPDATE: STABLE IN VITRO ACTIVITY FOLLOWING MORE THAN A DECADE OF CLINICAL USE AND SUMMARY OF ASSOCIATED RESISTANCE MECHANISMS.DRUG RESISTANCE UPDATES. VOL. 17. ISSUE 1-2. P. 1 -12 97 89% 28
2 SHAW, KJ , BARBACHYN, MR , (2011) THE OXAZOLIDINONES: PAST, PRESENT, AND FUTURE.ANTIMICROBIAL THERAPEUTICS REVIEWS: ANTIBIOTICS THAT TARGET THE RIBOSOME. VOL. 1241. ISSUE . P. 48 -70 83 79% 103
3 VARDAKAS, KZ , KIOUMIS, I , FALAGAS, ME , (2009) ASSOCIATION OF PHARMACOKINETIC AND PHARMACODYNAMIC ASPECTS OF LINEZOLID WITH INFECTION OUTCOME.CURRENT DRUG METABOLISM. VOL. 10. ISSUE 1. P. 2 -12 109 78% 10
4 MICHALSKA, K , KARPIUK, I , KROL, M , TYSKI, S , (2013) RECENT DEVELOPMENT OF POTENT ANALOGUES OF OXAZOLIDINONE ANTIBACTERIAL AGENTS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 21. ISSUE 3. P. 577-591 75 83% 36
5 HERRMANN, DJ , PEPPARD, WJ , LEDEBOER, NA , THEESFELD, ML , WEIGELT, JA , BUECHEL, BJ , (2008) LINEZOLID FOR THE TREATMENT OF DRUG-RESISTANT INFECTIONS.EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. VOL. 6. ISSUE 6. P. 825-848 110 71% 15
6 LONG, KS , VESTER, B , (2012) RESISTANCE TO LINEZOLID CAUSED BY MODIFICATIONS AT ITS BINDING SITE ON THE RIBOSOME.ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. VOL. 56. ISSUE 2. P. 603 -612 69 73% 76
7 CATTANEO, D , ALFFENAAR, JW , NEELY, M , (2016) DRUG MONITORING AND INDIVIDUAL DOSE OPTIMIZATION OF ANTIMICROBIAL DRUGS: OXAZOLIDINONES.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 12. ISSUE 5. P. 533 -544 61 79% 2
8 FERRANDEZ, O , URBINA, O , GRAU, S , (2017) CRITICAL ROLE OF TEDIZOLID IN THE TREATMENT OF ACUTE BACTERIAL SKIN AND SKIN STRUCTURE INFECTIONS.DRUG DESIGN DEVELOPMENT AND THERAPY. VOL. 11. ISSUE . P. 65 -82 60 81% 0
9 VARDAKAS, KZ , NTZIORA, F , FALAGAS, ME , (2007) LINEZOLID: EFFECTIVENESS AND SAFETY FOR APPROVED AND OFF-LABEL INDICATIONS.EXPERT OPINION ON PHARMACOTHERAPY. VOL. 8. ISSUE 14. P. 2381-2400 74 73% 18
10 CHIAPPINI, E , CONTI, C , GALLI, L , DE MARTINO, M , (2010) CLINICAL EFFICACY AND TOLERABILITY OF LINEZOLID IN PEDIATRIC PATIENTS: A SYSTEMATIC REVIEW.CLINICAL THERAPEUTICS. VOL. 32. ISSUE 1. P. 66-88 59 82% 24

Classes with closest relation at Level 1


Rank Class id link
1 11854 TELAVANCIN//CEFTAROLINE//LIPOGLYCOPEPTIDE
2 21421 STREPTOGRAMIN//QUINUPRISTIN DALFOPRISTIN//DALFOPRISTIN
3 2737 DAPTOMYCIN//HVISA//VANCOMYCIN
4 20372 CYTOXAZONE//2 OXAZOLIDINONE//5 ARYL 2 OXAZOLIDINONES
5 15552 TIGECYCLINE//GLYCYLCYCLINE//GAR 936
6 22341 AVIBACTAM//CEFTOLOZANE TAZOBACTAM//CEFTAZIDIME AVIBACTAM
7 35270 EVERNINOMICIN//EVERNIMICIN//ZIRACIN
8 176 ENTEROCOCCUS//ENTEROCOCCI//ENTEROCOCCUS FAECIUM
9 5145 VANCOMYCIN//TEICOPLANIN//RED MAN SYNDROME
10 8152 BURNS TRAUMA CRIT CARE//MEROPENEM//AUGMENTED RENAL CLEARANCE

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